Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium is maintained by ion pumps in the cell membrane. The cell membrane potential created by potassium and sodium ions allows the cell generate an action potential—a "spike" of electrical discharge. The ability of cells to produce electrical discharge is critical for body functions such as neurotransmission, muscle contraction, and heart function. Potassium is also an essential mineral needed to regulate water balance, blood pressure and levels of acidity.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Ramipril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Ramipril. |
| Fosinopril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Fosinopril. |
| Trandolapril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Trandolapril. |
| Benazepril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Benazepril. |
| Enalapril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Enalapril. |
| Moexipril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Moexipril. |
| Lisinopril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Lisinopril. |
| Perindopril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Perindopril. |
| Quinapril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Quinapril. |
| Omapatrilat | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Omapatrilat. |
| Rescinnamine | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Rescinnamine. |
| Captopril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Captopril. |
| Cilazapril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Cilazapril. |
| Spirapril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Spirapril. |
| Temocapril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Temocapril. |
| Enalaprilat | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Enalaprilat. |
| Imidapril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Imidapril. |
| Zofenopril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Zofenopril. |
| Delapril | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Delapril. |
| Benazeprilat | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Benazeprilat. |
| Fosinoprilat | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Fosinoprilat. |
| Ramiprilat | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Ramiprilat. |
| Trandolaprilat | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Trandolaprilat. |
| Moexiprilat | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Moexiprilat. |
| Perindoprilat | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Perindoprilat. |
| Quinaprilat | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Quinaprilat. |
| Cilazaprilat | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Cilazaprilat. |
| Sodium phosphate, monobasic | Potassium cation may increase the nephrotoxic activities of Sodium phosphate, monobasic. |
| Acemetacin | The therapeutic efficacy of Potassium cation can be decreased when used in combination with Acemetacin. |
| Triamterene | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Triamterene. |
| Spironolactone | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Spironolactone. |
| Amiloride | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Amiloride. |
| Eplerenone | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Eplerenone. |
| Canrenoic acid | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Canrenoic acid. |
| Canrenone | The risk or severity of hyperkalemia can be increased when Potassium cation is combined with Canrenone. |
| Magnesium sulfate | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium sulfate. |
| Mannitol | The risk or severity of dehydration can be increased when Potassium cation is combined with Mannitol. |
| Lactulose | The risk or severity of dehydration can be increased when Potassium cation is combined with Lactulose. |
| Lubiprostone | The risk or severity of dehydration can be increased when Potassium cation is combined with Lubiprostone. |
| Tegaserod | The risk or severity of dehydration can be increased when Potassium cation is combined with Tegaserod. |
| Magnesium oxide | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium oxide. |
| Magnesium cation | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium cation. |
| Sorbitol | The risk or severity of dehydration can be increased when Potassium cation is combined with Sorbitol. |
| Dantron | The risk or severity of dehydration can be increased when Potassium cation is combined with Dantron. |
| Oxyphenisatin | The risk or severity of dehydration can be increased when Potassium cation is combined with Oxyphenisatin. |
| Phenolphthalein | The risk or severity of dehydration can be increased when Potassium cation is combined with Phenolphthalein. |
| Prucalopride | The risk or severity of dehydration can be increased when Potassium cation is combined with Prucalopride. |
| Emodin | The risk or severity of dehydration can be increased when Potassium cation is combined with Emodin. |
| Linaclotide | The risk or severity of dehydration can be increased when Potassium cation is combined with Linaclotide. |
| Bisacodyl | The risk or severity of dehydration can be increased when Potassium cation is combined with Bisacodyl. |
| Magnesium hydroxide | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium hydroxide. |
| Bisoxatin | The risk or severity of dehydration can be increased when Potassium cation is combined with Bisoxatin. |
| Picosulfuric acid | The risk or severity of dehydration can be increased when Potassium cation is combined with Picosulfuric acid. |
| Magnesium trisilicate | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium trisilicate. |
| Polyethylene glycol | The risk or severity of dehydration can be increased when Potassium cation is combined with Polyethylene glycol. |
| Polycarbophil | The risk or severity of dehydration can be increased when Potassium cation is combined with Polycarbophil. |
| Magnesium acetate tetrahydrate | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium acetate tetrahydrate. |
| Monopotassium phosphate | The risk or severity of dehydration can be increased when Potassium cation is combined with Monopotassium phosphate. |
| Dipotassium phosphate | The risk or severity of dehydration can be increased when Potassium cation is combined with Dipotassium phosphate. |
| Glycerin | The risk or severity of dehydration can be increased when Potassium cation is combined with Glycerin. |
| Sodium sulfate | The risk or severity of dehydration can be increased when Potassium cation is combined with Sodium sulfate. |
| Magnesium carbonate | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium carbonate. |
| Potassium lactate | The risk or severity of dehydration can be increased when Potassium cation is combined with Potassium lactate. |
| Sodium fluorophosphate | The risk or severity of dehydration can be increased when Potassium cation is combined with Sodium fluorophosphate. |
| Mineral oil | The risk or severity of dehydration can be increased when Potassium cation is combined with Mineral oil. |
| Carboxymethylcellulose | The risk or severity of dehydration can be increased when Potassium cation is combined with Carboxymethylcellulose. |
| Docusate | The risk or severity of dehydration can be increased when Potassium cation is combined with Docusate. |
| Plantago seed | The risk or severity of dehydration can be increased when Potassium cation is combined with Plantago seed. |
| Magnesium citrate | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium citrate. |
| Castor oil | The risk or severity of dehydration can be increased when Potassium cation is combined with Castor oil. |
| Magnesium glycinate | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium glycinate. |
| Methylcellulose | The risk or severity of dehydration can be increased when Potassium cation is combined with Methylcellulose. |
| Sennosides | The risk or severity of dehydration can be increased when Potassium cation is combined with Sennosides. |
| Dehydrocholic acid | The risk or severity of dehydration can be increased when Potassium cation is combined with Dehydrocholic acid. |
| Lactitol | The risk or severity of dehydration can be increased when Potassium cation is combined with Lactitol. |
| Plecanatide | The risk or severity of dehydration can be increased when Potassium cation is combined with Plecanatide. |
| Gluconic Acid | The risk or severity of dehydration can be increased when Potassium cation is combined with Gluconic Acid. |
| Magnesium peroxide | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium peroxide. |
| Pentaerithrityl | The risk or severity of dehydration can be increased when Potassium cation is combined with Pentaerithrityl. |
| Sodium tartrate | The risk or severity of dehydration can be increased when Potassium cation is combined with Sodium tartrate. |
| Magnesium acetate | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium acetate. |
| Deacetylbisacodyl | The risk or severity of dehydration can be increased when Potassium cation is combined with Deacetylbisacodyl. |
| Sodium ascorbate | The risk or severity of dehydration can be increased when Potassium cation is combined with Sodium ascorbate. |
| Potassium sulfate | The risk or severity of dehydration can be increased when Potassium cation is combined with Potassium sulfate. |
| Sodium phosphate, dibasic | The risk or severity of dehydration can be increased when Potassium cation is combined with Sodium phosphate, dibasic. |
| Sodium phosphate, monobasic, unspecified form | The risk or severity of dehydration can be increased when Potassium cation is combined with Sodium phosphate, monobasic, unspecified form. |
| Sodium phosphate, dibasic, unspecified form | The risk or severity of dehydration can be increased when Potassium cation is combined with Sodium phosphate, dibasic, unspecified form. |
| Magnesium | The risk or severity of dehydration can be increased when Potassium cation is combined with Magnesium. |
| Sulfate ion | The risk or severity of dehydration can be increased when Potassium cation is combined with Sulfate ion. |
| Plantago ovata seed | The risk or severity of dehydration can be increased when Potassium cation is combined with Plantago ovata seed. |
| Oxyphenisatin acetate | The risk or severity of dehydration can be increased when Potassium cation is combined with Oxyphenisatin acetate. |
| Calcium polycarbophil | The risk or severity of dehydration can be increased when Potassium cation is combined with Calcium polycarbophil. |
| Konjac mannan | The risk or severity of dehydration can be increased when Potassium cation is combined with Konjac mannan. |
| Alloin | The risk or severity of dehydration can be increased when Potassium cation is combined with Alloin. |
| Frangula purshiana bark | The risk or severity of dehydration can be increased when Potassium cation is combined with Frangula purshiana bark. |
| Cefotiam | Cefotiam may decrease the excretion rate of Potassium cation which could result in a higher serum level. |
| Cefmenoxime | Cefmenoxime may decrease the excretion rate of Potassium cation which could result in a higher serum level. |
| Cefmetazole | Cefmetazole may decrease the excretion rate of Potassium cation which could result in a higher serum level. |
| Pamidronic acid | Pamidronic acid may decrease the excretion rate of Potassium cation which could result in a higher serum level. |
| Cefpiramide | Cefpiramide may decrease the excretion rate of Potassium cation which could result in a higher serum level. |