Vecuronium

DB01339

small molecule approved investigational

Deskripsi

Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents.

Struktur Molekul 2D

Berat 557.8274
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 51–80 minutes
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

100%

Rute Eliminasi

Fecal (40-75%) and renal (30% as unchanged drug and metabolites)

Interaksi Obat

1114 Data
Buprenorphine Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Vecuronium.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Vecuronium.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Vecuronium.
Hydrocodone Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Vecuronium.
Magnesium sulfate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Vecuronium may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Vecuronium.
Mirtazapine Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Vecuronium.
Orphenadrine Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Vecuronium.
Pramipexole Vecuronium may increase the sedative activities of Pramipexole.
Ropinirole Vecuronium may increase the sedative activities of Ropinirole.
Rotigotine Vecuronium may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Vecuronium.
Sodium oxybate Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Vecuronium.
Thalidomide Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Capreomycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Capreomycin.
Cyclosporine The therapeutic efficacy of Vecuronium can be increased when used in combination with Cyclosporine.
Doxycycline The therapeutic efficacy of Vecuronium can be increased when used in combination with Doxycycline.
Lymecycline The therapeutic efficacy of Vecuronium can be increased when used in combination with Lymecycline.
Piperacillin The therapeutic efficacy of Vecuronium can be increased when used in combination with Piperacillin.
Framycetin The therapeutic efficacy of Vecuronium can be increased when used in combination with Framycetin.
Clomocycline The therapeutic efficacy of Vecuronium can be increased when used in combination with Clomocycline.
Quinine The therapeutic efficacy of Vecuronium can be increased when used in combination with Quinine.
Vancomycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Vancomycin.
Tigecycline The therapeutic efficacy of Vecuronium can be increased when used in combination with Tigecycline.
Oxytetracycline The therapeutic efficacy of Vecuronium can be increased when used in combination with Oxytetracycline.
Chloroquine The therapeutic efficacy of Vecuronium can be increased when used in combination with Chloroquine.
Demeclocycline The therapeutic efficacy of Vecuronium can be increased when used in combination with Demeclocycline.
Mecamylamine The therapeutic efficacy of Vecuronium can be increased when used in combination with Mecamylamine.
Tobramycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Tobramycin.
Tetracycline The therapeutic efficacy of Vecuronium can be increased when used in combination with Tetracycline.
Gentamicin The therapeutic efficacy of Vecuronium can be increased when used in combination with Gentamicin.
Etacrynic acid The therapeutic efficacy of Vecuronium can be increased when used in combination with Etacrynic acid.
Quinidine The therapeutic efficacy of Vecuronium can be increased when used in combination with Quinidine.
Metacycline The therapeutic efficacy of Vecuronium can be increased when used in combination with Metacycline.
Netilmicin The therapeutic efficacy of Vecuronium can be increased when used in combination with Netilmicin.
Neomycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Neomycin.
Streptomycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Streptomycin.
Colistimethate The therapeutic efficacy of Vecuronium can be increased when used in combination with Colistimethate.
Kanamycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Kanamycin.
Dantrolene The therapeutic efficacy of Vecuronium can be increased when used in combination with Dantrolene.
Rolitetracycline The therapeutic efficacy of Vecuronium can be increased when used in combination with Rolitetracycline.
Magnesium oxide The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium oxide.
Magnesium cation The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium cation.
Paromomycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Paromomycin.
Lincomycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Lincomycin.
Ribostamycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Ribostamycin.
Geneticin The therapeutic efficacy of Vecuronium can be increased when used in combination with Geneticin.
Apramycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Apramycin.
Gentamicin C1a The therapeutic efficacy of Vecuronium can be increased when used in combination with Gentamicin C1a.
Neamine The therapeutic efficacy of Vecuronium can be increased when used in combination with Neamine.
Arbekacin The therapeutic efficacy of Vecuronium can be increased when used in combination with Arbekacin.
Viomycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Viomycin.
Puromycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Puromycin.
Magnesium hydroxide The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium hydroxide.
Magnesium trisilicate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium trisilicate.
Magnesium chloride The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium chloride.
Magnesium acetate tetrahydrate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium acetate tetrahydrate.
Magnesium carbonate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium carbonate.
Magnesium citrate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium citrate.
Magnesium glycinate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium glycinate.
Magnesium Aluminum Silicate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium Aluminum Silicate.
Dihydrostreptomycin The therapeutic efficacy of Vecuronium can be increased when used in combination with Dihydrostreptomycin.
Hygromycin B The therapeutic efficacy of Vecuronium can be increased when used in combination with Hygromycin B.
Sisomicin The therapeutic efficacy of Vecuronium can be increased when used in combination with Sisomicin.
Plazomicin The therapeutic efficacy of Vecuronium can be increased when used in combination with Plazomicin.
Magnesium silicate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium silicate.
Penimepicycline The therapeutic efficacy of Vecuronium can be increased when used in combination with Penimepicycline.
Magnesium aspartate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium aspartate.
Isepamicin The therapeutic efficacy of Vecuronium can be increased when used in combination with Isepamicin.
Magnesium gluconate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium gluconate.
Magnesium orotate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium orotate.
Magnesium phosphate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium phosphate.
Magnesium acetate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium acetate.
Procainamide The therapeutic efficacy of Vecuronium can be increased when used in combination with Procainamide.
Magnesium stearate The therapeutic efficacy of Vecuronium can be increased when used in combination with Magnesium stearate.
Colistin The therapeutic efficacy of Vecuronium can be increased when used in combination with Colistin.
Secretin porcine The therapeutic efficacy of Secretin porcine can be decreased when used in combination with Vecuronium.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Vecuronium.
Carbamazepine The serum concentration of Vecuronium can be decreased when it is combined with Carbamazepine.
Spironolactone Spironolactone may increase the neuromuscular blocking activities of Vecuronium.
Botulinum toxin type A The risk or severity of adverse effects can be increased when Vecuronium is combined with Botulinum toxin type A.
Botulinum toxin type B The risk or severity of adverse effects can be increased when Vecuronium is combined with Botulinum toxin type B.
Ethanol Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Vecuronium may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Vecuronium.
Fluvoxamine The risk or severity of adverse effects can be increased when Vecuronium is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Vecuronium is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Vecuronium is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Vecuronium is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Vecuronium is combined with Paroxetine.

Target Protein

Neuronal acetylcholine receptor subunit alpha-2 CHRNA2

Referensi & Sumber

Synthesis reference: Frans Herwig Jan Jansen, "Process to prepare pharmaceutical compositions containing vecuronium bromide and compositions produced thereby." U.S. Patent US5681573, issued January, 1969.

Contoh Produk & Brand

Produk: 44 • International brands: 0
Produk
  • Norcuron
    Injection, powder, lyophilized, for solution • 10 mg/1 • Intravenous • US • Approved
  • Norcuron Inj 10mg/vial
    Powder, for solution • 10 mg / vial • Intravenous • Canada • Approved
  • Vecuronium Bromide
    Injection, powder, lyophilized, for solution • 10 mg/1 • Intravenous • US • Approved
  • Vecuronium bromide
    Injection, powder, lyophilized, for solution • 1 mg/1mL • Intravenous • US • Generic • Approved
  • Vecuronium Bromide
    Injection, powder, lyophilized, for solution • 5 mg/1mL • Intravenous • US • Generic • Approved
  • Vecuronium Bromide
    Injection, powder, lyophilized, for solution • 5 mg/1mL • Intravenous • US • Generic • Approved
  • Vecuronium Bromide
    Injection, powder, lyophilized, for solution • 5 mg/1mL • Intravenous • US • Generic • Approved
  • Vecuronium Bromide
    Injection, powder, lyophilized, for solution • 5 mg/1mL • Intravenous • US • Generic • Approved
Menampilkan 8 dari 44 produk.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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