Cefonicid

DB01328

small molecule approved investigational

Deskripsi

A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.

Struktur Molekul 2D

Berat 542.566
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 4.5 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Not metabolized.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

795 Data
Probenecid The serum concentration of Cefonicid can be increased when it is combined with Probenecid.
Foscarnet The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Foscarnet.
Mannitol The risk or severity of nephrotoxicity can be increased when Mannitol is combined with Cefonicid.
Tenofovir disoproxil Cefonicid may increase the nephrotoxic activities of Tenofovir disoproxil.
Tenofovir alafenamide Cefonicid may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir Cefonicid may increase the nephrotoxic activities of Tenofovir.
Cyclosporine The risk or severity of nephrotoxicity can be increased when Cyclosporine is combined with Cefonicid.
Icosapent The risk or severity of nephrotoxicity can be increased when Icosapent is combined with Cefonicid.
Cefotiam The risk or severity of nephrotoxicity can be increased when Cefotiam is combined with Cefonicid.
Mesalazine The risk or severity of nephrotoxicity can be increased when Mesalazine is combined with Cefonicid.
Cefmenoxime The risk or severity of nephrotoxicity can be increased when Cefmenoxime is combined with Cefonicid.
Cefmetazole The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefonicid.
Indomethacin The risk or severity of nephrotoxicity can be increased when Indomethacin is combined with Cefonicid.
Triamterene The risk or severity of nephrotoxicity can be increased when Triamterene is combined with Cefonicid.
Cefpiramide The risk or severity of nephrotoxicity can be increased when Cefpiramide is combined with Cefonicid.
Loracarbef The risk or severity of nephrotoxicity can be increased when Loracarbef is combined with Cefonicid.
Cefalotin The risk or severity of nephrotoxicity can be increased when Cefalotin is combined with Cefonicid.
Nabumetone The risk or severity of nephrotoxicity can be increased when Nabumetone is combined with Cefonicid.
Ketorolac The risk or severity of nephrotoxicity can be increased when Ketorolac is combined with Cefonicid.
Tenoxicam The risk or severity of nephrotoxicity can be increased when Tenoxicam is combined with Cefonicid.
Celecoxib The risk or severity of nephrotoxicity can be increased when Celecoxib is combined with Cefonicid.
Cefotaxime The risk or severity of nephrotoxicity can be increased when Cefotaxime is combined with Cefonicid.
Tolmetin The risk or severity of nephrotoxicity can be increased when Tolmetin is combined with Cefonicid.
Rofecoxib The risk or severity of nephrotoxicity can be increased when Rofecoxib is combined with Cefonicid.
Fenoprofen The risk or severity of nephrotoxicity can be increased when Fenoprofen is combined with Cefonicid.
Valdecoxib The risk or severity of nephrotoxicity can be increased when Valdecoxib is combined with Cefonicid.
Diclofenac The risk or severity of nephrotoxicity can be increased when Diclofenac is combined with Cefonicid.
Sulindac The risk or severity of nephrotoxicity can be increased when Sulindac is combined with Cefonicid.
Bacitracin The risk or severity of nephrotoxicity can be increased when Bacitracin is combined with Cefonicid.
Amphotericin B The risk or severity of nephrotoxicity can be increased when Amphotericin B is combined with Cefonicid.
Cephaloglycin The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefonicid.
Adefovir dipivoxil The risk or severity of nephrotoxicity can be increased when Adefovir dipivoxil is combined with Cefonicid.
Pentamidine The risk or severity of nephrotoxicity can be increased when Pentamidine is combined with Cefonicid.
Mefenamic acid The risk or severity of nephrotoxicity can be increased when Mefenamic acid is combined with Cefonicid.
Naproxen The risk or severity of nephrotoxicity can be increased when Naproxen is combined with Cefonicid.
Sulfasalazine The risk or severity of nephrotoxicity can be increased when Sulfasalazine is combined with Cefonicid.
Phenylbutazone The risk or severity of nephrotoxicity can be increased when Phenylbutazone is combined with Cefonicid.
Meloxicam The risk or severity of methemoglobinemia can be increased when Cefonicid is combined with Meloxicam.
Carprofen The risk or severity of nephrotoxicity can be increased when Carprofen is combined with Cefonicid.
Tacrolimus The risk or severity of nephrotoxicity can be increased when Tacrolimus is combined with Cefonicid.
Etacrynic acid The risk or severity of nephrotoxicity can be increased when Etacrynic acid is combined with Cefonicid.
Ceforanide The risk or severity of nephrotoxicity can be increased when Ceforanide is combined with Cefonicid.
Salicylic acid The risk or severity of nephrotoxicity can be increased when Salicylic acid is combined with Cefonicid.
Acetylsalicylic acid The risk or severity of nephrotoxicity can be increased when Acetylsalicylic acid is combined with Cefonicid.
Hydrochlorothiazide The risk or severity of nephrotoxicity can be increased when Hydrochlorothiazide is combined with Cefonicid.
Balsalazide The risk or severity of nephrotoxicity can be increased when Balsalazide is combined with Cefonicid.
Cefditoren The risk or severity of nephrotoxicity can be increased when Cefditoren is combined with Cefonicid.
Atazanavir The risk or severity of nephrotoxicity can be increased when Atazanavir is combined with Cefonicid.
Colistimethate The risk or severity of nephrotoxicity can be increased when Colistimethate is combined with Cefonicid.
Cefuroxime The risk or severity of nephrotoxicity can be increased when Cefuroxime is combined with Cefonicid.
Cefapirin The risk or severity of nephrotoxicity can be increased when Cefapirin is combined with Cefonicid.
Cefprozil The risk or severity of nephrotoxicity can be increased when Cefprozil is combined with Cefonicid.
Olsalazine The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Olsalazine.
Lumiracoxib The risk or severity of nephrotoxicity can be increased when Lumiracoxib is combined with Cefonicid.
Cefamandole The risk or severity of nephrotoxicity can be increased when Cefamandole is combined with Cefonicid.
Cefazolin The risk or severity of nephrotoxicity can be increased when Cefazolin is combined with Cefonicid.
Cefoperazone The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Cefoperazone.
Cefoxitin The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Cefoxitin.
Ceftizoxime The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Ceftizoxime.
Magnesium salicylate The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Magnesium salicylate.
Salsalate The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Salsalate.
Choline magnesium trisalicylate The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Choline magnesium trisalicylate.
Cefepime The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Cefepime.
Cefacetrile The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Cefacetrile.
Cefpodoxime The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Cefpodoxime.
Antrafenine The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Antrafenine.
Aminophenazone The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Aminophenazone.
Antipyrine The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Antipyrine.
Tiaprofenic acid The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Tiaprofenic acid.
Lopinavir The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Lopinavir.
Etoricoxib The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Etoricoxib.
Hydrolyzed Cephalothin The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Hydrolyzed Cephalothin.
Cephalothin Group The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Cephalothin Group.
Oxyphenbutazone The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Oxyphenbutazone.
Latamoxef The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Latamoxef.
Nimesulide The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Nimesulide.
Benoxaprofen The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Benoxaprofen.
Metamizole The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Metamizole.
Zomepirac The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Zomepirac.
Ceftobiprole The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Ceftobiprole.
Cimicoxib The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Cimicoxib.
Ceftaroline fosamil The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Ceftaroline fosamil.
Lornoxicam The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Lornoxicam.
Zaltoprofen The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Zaltoprofen.
Azapropazone The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Azapropazone.
Parecoxib The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Parecoxib.
Salicylamide The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Salicylamide.
Kebuzone The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Kebuzone.
Isoxicam The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Isoxicam.
Indoprofen The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Indoprofen.
Ibuproxam The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Ibuproxam.
Floctafenine The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Floctafenine.
Fenbufen The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Fenbufen.
Etofenamate The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Etofenamate.
Epirizole The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Epirizole.
Cefaloridine The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Cefaloridine.
Cefminox The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Cefminox.
Dexibuprofen The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Dexibuprofen.
Droxicam The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Droxicam.
Tolfenamic acid The risk or severity of nephrotoxicity can be increased when Cefonicid is combined with Tolfenamic acid.

Target Protein

Penicillin-binding protein 1A mrcA
Peptidoglycan synthase FtsI ftsI
Penicillin-binding protein 1B mrcB
D-alanyl-D-alanine carboxypeptidase DacB dacB
Penicillin-binding protein 2 mrdA

Referensi & Sumber

Synthesis reference: Theodore John Polansky, "Crystalline benzathine salt of cefonicid and its preparation." U.S. Patent US5705496, issued October, 1992.

Contoh Produk & Brand

Produk: 0 • International brands: 2
International Brands
  • Monocid
  • Praticef

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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