St. John's Wort

DB01323

biotech approved investigational nutraceutical

Deskripsi

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1504 Data
Aripiprazole The metabolism of Aripiprazole can be increased when combined with St. John's Wort.
Buprenorphine St. John's Wort may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of St. John's Wort.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of St. John's Wort.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of St. John's Wort.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of St. John's Wort.
Magnesium sulfate The therapeutic efficacy of St. John's Wort can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine St. John's Wort may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine St. John's Wort may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of St. John's Wort.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of St. John's Wort.
Orphenadrine St. John's Wort may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde St. John's Wort may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Pramipexole St. John's Wort may increase the sedative activities of Pramipexole.
Ropinirole St. John's Wort may increase the sedative activities of Ropinirole.
Rotigotine St. John's Wort may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with St. John's Wort.
Sodium oxybate St. John's Wort may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant St. John's Wort may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of St. John's Wort.
Thalidomide St. John's Wort may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem St. John's Wort may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Dabrafenib The serum concentration of St. John's Wort can be decreased when it is combined with Dabrafenib.
Luliconazole The serum concentration of St. John's Wort can be increased when it is combined with Luliconazole.
Afatinib The serum concentration of Afatinib can be decreased when it is combined with St. John's Wort.
Brentuximab vedotin The serum concentration of Brentuximab vedotin can be decreased when it is combined with St. John's Wort.
Dabigatran etexilate The serum concentration of Dabigatran etexilate can be decreased when it is combined with St. John's Wort.
Linagliptin The serum concentration of Linagliptin can be decreased when it is combined with St. John's Wort.
Sofosbuvir The serum concentration of Sofosbuvir can be decreased when it is combined with St. John's Wort.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with St. John's Wort.
Atomoxetine The metabolism of Atomoxetine can be decreased when combined with St. John's Wort.
Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with St. John's Wort.
Ifosfamide The metabolism of Ifosfamide can be increased when combined with St. John's Wort.
Ledipasvir The serum concentration of Ledipasvir can be decreased when it is combined with St. John's Wort.
Perampanel The metabolism of Perampanel can be increased when combined with St. John's Wort.
Warfarin The metabolism of Warfarin can be increased when combined with St. John's Wort.
Acenocoumarol The metabolism of Acenocoumarol can be increased when combined with St. John's Wort.
(R)-warfarin The metabolism of (R)-warfarin can be increased when combined with St. John's Wort.
R,S-Warfarin alcohol The metabolism of R,S-Warfarin alcohol can be increased when combined with St. John's Wort.
S,R-Warfarin alcohol The metabolism of S,R-Warfarin alcohol can be increased when combined with St. John's Wort.
(S)-Warfarin The metabolism of (S)-Warfarin can be increased when combined with St. John's Wort.
Dicoumarol The risk or severity of adverse effects can be increased when St. John's Wort is combined with Dicoumarol.
Phenindione The risk or severity of adverse effects can be increased when St. John's Wort is combined with Phenindione.
Coumarin The risk or severity of adverse effects can be increased when St. John's Wort is combined with Coumarin.
Tioclomarol The risk or severity of adverse effects can be increased when St. John's Wort is combined with Tioclomarol.
4-hydroxycoumarin The risk or severity of adverse effects can be increased when St. John's Wort is combined with 4-hydroxycoumarin.
Fluindione The risk or severity of adverse effects can be increased when St. John's Wort is combined with Fluindione.
Clorindione The risk or severity of adverse effects can be increased when St. John's Wort is combined with Clorindione.
Mirtazapine St. John's Wort may increase the serotonergic activities of Mirtazapine.
Ethanol St. John's Wort may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine St. John's Wort may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of St. John's Wort.
Zimelidine The risk or severity of adverse effects can be increased when St. John's Wort is combined with Zimelidine.
Seproxetine The risk or severity of adverse effects can be increased when St. John's Wort is combined with Seproxetine.
Ritanserin The risk or severity of adverse effects can be increased when St. John's Wort is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when St. John's Wort is combined with Alaproclate.
Duloxetine The risk or severity of adverse effects can be increased when St. John's Wort is combined with Duloxetine.
Lumacaftor The serum concentration of St. John's Wort can be decreased when it is combined with Lumacaftor.
Lovastatin The serum concentration of Lovastatin can be decreased when it is combined with St. John's Wort.
Simvastatin The serum concentration of Simvastatin can be decreased when it is combined with St. John's Wort.
Atorvastatin The serum concentration of Atorvastatin can be decreased when it is combined with St. John's Wort.
Fluvastatin The serum concentration of Fluvastatin can be decreased when it is combined with St. John's Wort.
Rosuvastatin The serum concentration of Rosuvastatin can be decreased when it is combined with St. John's Wort.
Ranolazine The serum concentration of Ranolazine can be decreased when it is combined with St. John's Wort.
Doxorubicin The serum concentration of Doxorubicin can be decreased when it is combined with St. John's Wort.
Vincristine The serum concentration of Vincristine can be decreased when it is combined with St. John's Wort.
Methylene blue St. John's Wort may increase the serotonergic activities of Methylene blue.
Erlotinib The metabolism of Erlotinib can be increased when combined with St. John's Wort.
Voriconazole The serum concentration of Voriconazole can be decreased when it is combined with St. John's Wort.
Efavirenz The serum concentration of Efavirenz can be decreased when it is combined with St. John's Wort.
Guanfacine The serum concentration of Guanfacine can be decreased when it is combined with St. John's Wort.
Benzatropine The metabolism of Benzatropine can be decreased when combined with St. John's Wort.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with St. John's Wort.
Lamotrigine The risk or severity of CNS depression can be increased when Lamotrigine is combined with St. John's Wort.
Flupentixol The risk or severity of CNS depression can be increased when Flupentixol is combined with St. John's Wort.
Umeclidinium The metabolism of Umeclidinium can be decreased when combined with St. John's Wort.
Revefenacin The metabolism of Revefenacin can be decreased when combined with St. John's Wort.
Brompheniramine The risk or severity of CNS depression can be increased when Brompheniramine is combined with St. John's Wort.
Cocaine The risk or severity of serotonin syndrome can be increased when Cocaine is combined with St. John's Wort.
Atazanavir The serum concentration of Atazanavir can be decreased when it is combined with St. John's Wort.
Nifedipine The serum concentration of Nifedipine can be decreased when it is combined with St. John's Wort.
Propafenone The serum concentration of Propafenone can be decreased when it is combined with St. John's Wort.
Quetiapine The serum concentration of Quetiapine can be decreased when it is combined with St. John's Wort.
Lapatinib The serum concentration of Lapatinib can be decreased when it is combined with St. John's Wort.
Paliperidone The serum concentration of Paliperidone can be decreased when it is combined with St. John's Wort.
Telaprevir The serum concentration of Telaprevir can be decreased when it is combined with St. John's Wort.
Isavuconazonium The serum concentration of Isavuconazonium can be decreased when it is combined with St. John's Wort.
Lurasidone The serum concentration of Lurasidone can be decreased when it is combined with St. John's Wort.
Cobicistat The serum concentration of Cobicistat can be decreased when it is combined with St. John's Wort.
Daclatasvir The serum concentration of Daclatasvir can be decreased when it is combined with St. John's Wort.
Artemether The serum concentration of dihydroartemisinin, an active metabolite of Artemether, can be decreased when used in combination with St. John's Wort.
Lumefantrine The serum concentration of Lumefantrine can be decreased when it is combined with St. John's Wort.
Insulin human The therapeutic efficacy of Insulin human can be decreased when used in combination with St. John's Wort.
Insulin lispro The therapeutic efficacy of Insulin lispro can be decreased when used in combination with St. John's Wort.
Insulin glargine The therapeutic efficacy of Insulin glargine can be decreased when used in combination with St. John's Wort.
Insulin pork The therapeutic efficacy of Insulin pork can be decreased when used in combination with St. John's Wort.
Troglitazone The therapeutic efficacy of Troglitazone can be decreased when used in combination with St. John's Wort.
Glimepiride The therapeutic efficacy of Glimepiride can be decreased when used in combination with St. John's Wort.
Sulfisoxazole The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with St. John's Wort.
Acarbose The therapeutic efficacy of Acarbose can be decreased when used in combination with St. John's Wort.

Referensi & Sumber

Synthesis reference: Trevor Percival Castor, Theodore Abraham Tyler, Richard Joseph Student, "Methods for making Hypericum fractions and St. John's Wort products." U.S. Patent US6291241, issued December, 1998.
Artikel (PubMed)
  • PMID: 12153829
    Lecrubier Y, Clerc G, Didi R, Kieser M: Efficacy of St. John's wort extract WS 5570 in major depression: a double-blind, placebo-controlled trial. Am J Psychiatry. 2002 Aug;159(8):1361-6.
  • PMID: 16423519
    Randlov C, Mehlsen J, Thomsen CF, Hedman C, von Fircks H, Winther K: The efficacy of St. John's Wort in patients with minor depressive symptoms or dysthymia--a double-blind placebo-controlled study. Phytomedicine. 2006 Mar;13(4):215-21. Epub 2006 Jan 19.
  • PMID: 11939866
    Authors unspecified: Effect of Hypericum perforatum (St John's wort) in major depressive disorder: a randomized controlled trial. JAMA. 2002 Apr 10;287(14):1807-14.

Contoh Produk & Brand

Produk: 29 • International brands: 0
Produk
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    Liquid • - • Topical • US • OTC
  • Dynamiclear Rapid
    Liquid • - • Topical • US • OTC
  • Ethical Herbal's ST. John's Wort
    Tablet • 900 mg / tab • Oral • Canada • Approved
  • Ethical Herbals ST. John's Wort
    Tablet • 150 mg/1 • Oral • Canada • OTC • Approved
  • Ethical Herbals ST. John's Wort
    Tablet • 300 mg/1 • Oral • Canada • OTC • Approved
  • Ethical Herbals ST.john's Wort
    Tablet • 300 mg • Oral • Canada • Approved
  • Felis Forte Capsules 425mg
    Capsule • 425 mg / cap • Oral • Canada • OTC • Approved
  • Felis Tablets 250mg
    Tablet • 250 mg / tab • Oral • Canada • OTC • Approved
Menampilkan 8 dari 29 produk.

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