Peringatan Keamanan

Symptoms of overdose include abdominal irritation, central nervous system depression, coma, extremely slow heartbeat, heart failure, lethargy, low blood pressure, and wheezing.

Practolol

DB01297

small molecule approved

Deskripsi

A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.

Struktur Molekul 2D

Berat 266.3361
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

2 Data
  • 1. Avoid alcohol.
  • 2. Avoid natural licorice.

Interaksi Obat

1302 Data
Ceritinib Practolol may increase the bradycardic activities of Ceritinib.
Ivabradine Practolol may increase the bradycardic activities of Ivabradine.
Ruxolitinib Ruxolitinib may increase the bradycardic activities of Practolol.
Alfuzosin Alfuzosin may increase the hypotensive activities of Practolol.
Amifostine Practolol may increase the hypotensive activities of Amifostine.
Diazoxide Diazoxide may increase the hypotensive activities of Practolol.
Methylphenidate Methylphenidate may decrease the antihypertensive activities of Practolol.
Dexmethylphenidate Dexmethylphenidate may decrease the antihypertensive activities of Practolol.
Obinutuzumab Practolol may increase the hypotensive activities of Obinutuzumab.
Pentoxifylline Pentoxifylline may increase the hypotensive activities of Practolol.
Rituximab Practolol may increase the hypotensive activities of Rituximab.
Desmopressin Desmopressin may decrease the antihypertensive activities of Practolol.
Zolmitriptan Zolmitriptan may decrease the antihypertensive activities of Practolol.
Doxapram Doxapram may decrease the antihypertensive activities of Practolol.
Sumatriptan Sumatriptan may decrease the antihypertensive activities of Practolol.
Phenmetrazine Phenmetrazine may decrease the antihypertensive activities of Practolol.
Naratriptan Naratriptan may decrease the antihypertensive activities of Practolol.
Rizatriptan Rizatriptan may decrease the antihypertensive activities of Practolol.
Dopamine Dopamine may decrease the antihypertensive activities of Practolol.
Frovatriptan Frovatriptan may decrease the antihypertensive activities of Practolol.
Dutasteride Dutasteride may decrease the antihypertensive activities of Practolol.
Finasteride Finasteride may decrease the antihypertensive activities of Practolol.
Yohimbine Yohimbine may decrease the antihypertensive activities of Practolol.
Solifenacin Solifenacin may decrease the antihypertensive activities of Practolol.
Epicaptopril Epicaptopril may decrease the antihypertensive activities of Practolol.
1-benzylimidazole 1-benzylimidazole may decrease the antihypertensive activities of Practolol.
Amineptine Amineptine may decrease the antihypertensive activities of Practolol.
Flibanserin Flibanserin may decrease the antihypertensive activities of Practolol.
Naluzotan Naluzotan may decrease the antihypertensive activities of Practolol.
Nitrous oxide Nitrous oxide may decrease the antihypertensive activities of Practolol.
Cinitapride Cinitapride may decrease the antihypertensive activities of Practolol.
Lurasidone Lurasidone may decrease the antihypertensive activities of Practolol.
Tyramine Tyramine may decrease the antihypertensive activities of Practolol.
Ifenprodil Ifenprodil may decrease the antihypertensive activities of Practolol.
Dimetacrine Dimetacrine may decrease the antihypertensive activities of Practolol.
Butriptyline Butriptyline may decrease the antihypertensive activities of Practolol.
Moxisylyte Moxisylyte may decrease the antihypertensive activities of Practolol.
Tianeptine Tianeptine may decrease the antihypertensive activities of Practolol.
Oxaprotiline Oxaprotiline may decrease the antihypertensive activities of Practolol.
Atipamezole Atipamezole may decrease the antihypertensive activities of Practolol.
Tetrahydrocannabivarin Tetrahydrocannabivarin may decrease the antihypertensive activities of Practolol.
Piclozotan Piclozotan may decrease the antihypertensive activities of Practolol.
Siponimod Siponimod may decrease the antihypertensive activities of Practolol.
Idazoxan Idazoxan may decrease the antihypertensive activities of Practolol.
Tramazoline Tramazoline may decrease the antihypertensive activities of Practolol.
Amitriptylinoxide Amitriptylinoxide may decrease the antihypertensive activities of Practolol.
Dibenzepin Dibenzepin may decrease the antihypertensive activities of Practolol.
Quinupramine Quinupramine may decrease the antihypertensive activities of Practolol.
Trichloroethylene Trichloroethylene may decrease the antihypertensive activities of Practolol.
Fenozolone Fenozolone may decrease the antihypertensive activities of Practolol.
Melitracen Melitracen may decrease the antihypertensive activities of Practolol.
Lofepramine Lofepramine may decrease the antihypertensive activities of Practolol.
Xenon Xenon may decrease the antihypertensive activities of Practolol.
Iprindole Iprindole may decrease the antihypertensive activities of Practolol.
Buflomedil Buflomedil may decrease the antihypertensive activities of Practolol.
Diethyl ether Diethyl ether may decrease the antihypertensive activities of Practolol.
Imipramine oxide Imipramine oxide may decrease the antihypertensive activities of Practolol.
Mefenorex Mefenorex may decrease the antihypertensive activities of Practolol.
5-methoxy-N,N-dimethyltryptamine 5-methoxy-N,N-dimethyltryptamine may decrease the antihypertensive activities of Practolol.
Quinoline Yellow WS Quinoline Yellow WS may decrease the antihypertensive activities of Practolol.
Solriamfetol Solriamfetol may decrease the antihypertensive activities of Practolol.
Sufentanil Sufentanil may decrease the antihypertensive activities of Practolol.
Isoflurane Isoflurane may decrease the antihypertensive activities of Practolol.
Propofol Propofol may decrease the antihypertensive activities of Practolol.
Remifentanil Remifentanil may decrease the antihypertensive activities of Practolol.
Halothane Halothane may decrease the antihypertensive activities of Practolol.
Desflurane Desflurane may decrease the antihypertensive activities of Practolol.
Sevoflurane Sevoflurane may decrease the antihypertensive activities of Practolol.
Protriptyline Protriptyline may decrease the antihypertensive activities of Practolol.
Opipramol Opipramol may decrease the antihypertensive activities of Practolol.
Selpercatinib Selpercatinib may decrease the antihypertensive activities of Practolol.
Naxitamab Naxitamab may decrease the antihypertensive activities of Practolol.
Cannabidiol The metabolism of Practolol can be decreased when combined with Cannabidiol.
Amiodarone The therapeutic efficacy of Practolol can be increased when used in combination with Amiodarone.
Bupivacaine The serum concentration of Bupivacaine can be increased when it is combined with Practolol.
Dipyridamole Dipyridamole may increase the bradycardic activities of Practolol.
Disopyramide Disopyramide may increase the bradycardic activities of Practolol.
Dronedarone Dronedarone may increase the bradycardic activities of Practolol.
Fingolimod Practolol may increase the bradycardic activities of Fingolimod.
Floctafenine The risk or severity of adverse effects can be increased when Practolol is combined with Floctafenine.
Mepivacaine The serum concentration of Mepivacaine can be increased when it is combined with Practolol.
Methacholine Practolol may increase the bronchoconstrictory activities of Methacholine.
Midodrine The therapeutic efficacy of Midodrine can be decreased when used in combination with Practolol.
Nifedipine The risk or severity of congestive heart failure and hypotension can be increased when Nifedipine is combined with Practolol.
Propafenone The risk or severity of adverse effects can be increased when Propafenone is combined with Practolol.
Regorafenib Regorafenib may increase the bradycardic activities of Practolol.
Reserpine Reserpine may increase the hypotensive activities of Practolol.
Deserpidine Deserpidine may increase the hypotensive activities of Practolol.
Guanethidine Guanethidine may increase the hypotensive activities of Practolol.
Rivastigmine Practolol may increase the bradycardic activities of Rivastigmine.
Mirabegron The serum concentration of Practolol can be increased when it is combined with Mirabegron.
Molsidomine Molsidomine may increase the hypotensive activities of Practolol.
Insulin argine Practolol may increase the hypoglycemic activities of Insulin argine.
Remikiren Remikiren may increase the hypotensive activities of Practolol.
Guanadrel Guanadrel may increase the hypotensive activities of Practolol.
Bosentan Bosentan may increase the hypotensive activities of Practolol.
Candoxatril Candoxatril may increase the hypotensive activities of Practolol.
Metyrosine Metyrosine may increase the hypotensive activities of Practolol.
Cryptenamine Cryptenamine may increase the hypotensive activities of Practolol.
Dorzolamide Dorzolamide may increase the hypotensive activities of Practolol.

Target Protein

Beta-1 adrenergic receptor ADRB1

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 0 • International brands: 0
Belum ada data produk/brand untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field produk/brand.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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