Peringatan Keamanan

The principal symptoms of overdose are convulsions and gangrene. Other symptoms include bradycardia, confusion, diarrhoea, dizziness, dyspnoea, drowsiness, fast and/or weak pulse, miosis, hypercoagulability, loss of consciousness, nausea and vomiting, numbness and coldness of the extremities, pain in the chest, peripheral vasoconstriction, respiratory depression, rise or fall in blood pressure, severe cramping of the uterus, tachycardia, tingling, and unusual thirst.

Ergometrine

DB01253

small molecule approved

Deskripsi

An ergot alkaloid with uterine and vascular smooth muscle contractile properties.

Struktur Molekul 2D

Berat 325.4048
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) t<sub>1/2 &alpha;</sub>=10 minutes; t<sub>1/2 &beta;</sub>=2 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Absorption is rapid and complete after oral or intramuscular administration.

Metabolisme

Hepatic.

Rute Eliminasi

Thought to be eliminated by non-renal mechanisms (i.e. hepatic metabolism, excretion in feces)

Interaksi Obat

1291 Data
Carboprost tromethamine Carboprost tromethamine may increase the uterotonic activities of Ergometrine.
Valsartan Ergometrine may decrease the antihypertensive activities of Valsartan.
Ramipril Ergometrine may decrease the antihypertensive activities of Ramipril.
Remikiren Ergometrine may decrease the antihypertensive activities of Remikiren.
Torasemide Ergometrine may decrease the antihypertensive activities of Torasemide.
Olmesartan Ergometrine may decrease the antihypertensive activities of Olmesartan.
Chlorthalidone Ergometrine may decrease the antihypertensive activities of Chlorthalidone.
Nitroprusside Ergometrine may decrease the antihypertensive activities of Nitroprusside.
Minoxidil Ergometrine may decrease the antihypertensive activities of Minoxidil.
Treprostinil Ergometrine may decrease the antihypertensive activities of Treprostinil.
Bendroflumethiazide Ergometrine may decrease the antihypertensive activities of Bendroflumethiazide.
Fosinopril Ergometrine may decrease the antihypertensive activities of Fosinopril.
Trandolapril Ergometrine may decrease the antihypertensive activities of Trandolapril.
Metolazone Ergometrine may decrease the antihypertensive activities of Metolazone.
Benazepril Ergometrine may decrease the antihypertensive activities of Benazepril.
Cyclothiazide Ergometrine may decrease the antihypertensive activities of Cyclothiazide.
Candoxatril Ergometrine may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Ergometrine may decrease the antihypertensive activities of Mecamylamine.
Moexipril Ergometrine may decrease the antihypertensive activities of Moexipril.
Lisinopril Ergometrine may decrease the antihypertensive activities of Lisinopril.
Hydroflumethiazide Ergometrine may decrease the antihypertensive activities of Hydroflumethiazide.
Cryptenamine Ergometrine may decrease the antihypertensive activities of Cryptenamine.
Perindopril Ergometrine may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Ergometrine may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Ergometrine may decrease the antihypertensive activities of Fenoldopam.
Eprosartan Ergometrine may decrease the antihypertensive activities of Eprosartan.
Chlorothiazide Ergometrine may decrease the antihypertensive activities of Chlorothiazide.
Quinapril Ergometrine may decrease the antihypertensive activities of Quinapril.
Telmisartan Ergometrine may decrease the antihypertensive activities of Telmisartan.
Hydrochlorothiazide Ergometrine may decrease the antihypertensive activities of Hydrochlorothiazide.
Trichlormethiazide Ergometrine may decrease the antihypertensive activities of Trichlormethiazide.
Deserpidine Ergometrine may decrease the antihypertensive activities of Deserpidine.
Pentolinium Ergometrine may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Ergometrine may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Ergometrine may decrease the antihypertensive activities of Diazoxide.
Captopril Ergometrine may decrease the antihypertensive activities of Captopril.
Epoprostenol Ergometrine may decrease the antihypertensive activities of Epoprostenol.
Polythiazide Ergometrine may decrease the antihypertensive activities of Polythiazide.
Cilazapril Ergometrine may decrease the antihypertensive activities of Cilazapril.
Saprisartan Ergometrine may decrease the antihypertensive activities of Saprisartan.
Spirapril Ergometrine may decrease the antihypertensive activities of Spirapril.
Tienilic acid Ergometrine may decrease the antihypertensive activities of Tienilic acid.
Diethylnorspermine Ergometrine may decrease the antihypertensive activities of Diethylnorspermine.
Temocapril Ergometrine may decrease the antihypertensive activities of Temocapril.
Nicorandil Ergometrine may decrease the antihypertensive activities of Nicorandil.
Rauwolfia serpentina root Ergometrine may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Ergometrine may decrease the antihypertensive activities of Enalaprilat.
Angiotensin 1-7 Ergometrine may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Ergometrine may decrease the antihypertensive activities of Imidapril.
BQ-123 Ergometrine may decrease the antihypertensive activities of BQ-123.
Cicletanine Ergometrine may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Ergometrine may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Ergometrine may decrease the antihypertensive activities of Zofenopril.
Guanoxan Ergometrine may decrease the antihypertensive activities of Guanoxan.
Delapril Ergometrine may decrease the antihypertensive activities of Delapril.
Vincamine Ergometrine may decrease the antihypertensive activities of Vincamine.
Linsidomine Ergometrine may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Ergometrine may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Ergometrine may decrease the antihypertensive activities of Tolonidine.
Endralazine Ergometrine may decrease the antihypertensive activities of Endralazine.
Cadralazine Ergometrine may decrease the antihypertensive activities of Cadralazine.
Cyclopenthiazide Ergometrine may decrease the antihypertensive activities of Cyclopenthiazide.
Bietaserpine Ergometrine may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Ergometrine may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Ergometrine may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Ergometrine may decrease the antihypertensive activities of Guanoclor.
Muzolimine Ergometrine may decrease the antihypertensive activities of Muzolimine.
Xipamide Ergometrine may decrease the antihypertensive activities of Xipamide.
Candesartan Ergometrine may decrease the antihypertensive activities of Candesartan.
Tocopherylquinone Ergometrine may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Ergometrine may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Ergometrine may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Ergometrine may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Ergometrine may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Ergometrine may decrease the antihypertensive activities of Quinaprilat.
Furosemide Ergometrine may decrease the antihypertensive activities of Furosemide.
Enalapril Ergometrine may decrease the antihypertensive activities of Enalapril.
Nimodipine Ergometrine may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Ergometrine may decrease the antihypertensive activities of Nisoldipine.
Lercanidipine Ergometrine may decrease the antihypertensive activities of Lercanidipine.
Bosentan Ergometrine may decrease the antihypertensive activities of Bosentan.
Eplerenone Ergometrine may decrease the antihypertensive activities of Eplerenone.
Indapamide Ergometrine may decrease the antihypertensive activities of Indapamide.
Tadalafil Ergometrine may decrease the antihypertensive activities of Tadalafil.
Felodipine Ergometrine may decrease the antihypertensive activities of Felodipine.
Irbesartan Ergometrine may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Ergometrine may decrease the antihypertensive activities of Nitrendipine.
Bepridil Ergometrine may decrease the antihypertensive activities of Bepridil.
Hydralazine Ergometrine may decrease the antihypertensive activities of Hydralazine.
Mibefradil Ergometrine may decrease the antihypertensive activities of Mibefradil.
Sitaxentan Ergometrine may decrease the antihypertensive activities of Sitaxentan.
Pinacidil Ergometrine may decrease the antihypertensive activities of Pinacidil.
Riociguat Ergometrine may decrease the antihypertensive activities of Riociguat.
Macitentan Ergometrine may decrease the antihypertensive activities of Macitentan.
Aliskiren Ergometrine may decrease the antihypertensive activities of Aliskiren.
Efonidipine Ergometrine may decrease the antihypertensive activities of Efonidipine.
Lacidipine Ergometrine may decrease the antihypertensive activities of Lacidipine.
Manidipine Ergometrine may decrease the antihypertensive activities of Manidipine.
Naftopidil Ergometrine may decrease the antihypertensive activities of Naftopidil.
Dexniguldipine Ergometrine may decrease the antihypertensive activities of Dexniguldipine.

Target Protein

Alpha-1A adrenergic receptor ADRA1A
D(2) dopamine receptor DRD2

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 7 • International brands: 1
Produk
  • Ergonovine Maleate
    Tablet • 0.2 mg/1 • Oral • US
  • Ergonovine Maleate Injection
    Solution • 0.25 mg / mL • Intramuscular; Intravenous • Canada • Approved
  • Ergonovine Maleate Injection USP
    Solution • .25 mg / mL • Intramuscular; Intravenous • Canada • Approved
  • Ergonovine Maleate Injection USP
    Solution • 0.25 mg / mL • Intramuscular; Intravenous • Canada • Approved
  • Ergonovine Maleate Injection USP, 0.25mg/ml
    Solution • 0.25 mg / mL • Intramuscular; Intravenous • Canada • Approved
  • Ergotrate Maleate
    Injection, solution • 0.2 mg/1mL • Intramuscular • US
  • Ergotrate Maleate Tablet 1572 0.2mg
    Tablet • .2 mg / tab • Oral • Canada • Approved
International Brands
  • Ergotrate

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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