Mitiglinide

DB01252

small molecule investigational

Deskripsi

Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.

Struktur Molekul 2D

Berat 315.413
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

615 Data
Pegvisomant The risk or severity of hypoglycemia can be increased when Pegvisomant is combined with Mitiglinide.
Lipoic acid The risk or severity of hypoglycemia can be increased when Lipoic acid is combined with Mitiglinide.
Moxifloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Moxifloxacin.
Grepafloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Grepafloxacin.
Enoxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Enoxacin.
Pefloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Pefloxacin.
Ciprofloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Ciprofloxacin.
Trovafloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Trovafloxacin.
Nalidixic acid The therapeutic efficacy of Mitiglinide can be increased when used in combination with Nalidixic acid.
Rosoxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Rosoxacin.
Cinoxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Cinoxacin.
Lomefloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Lomefloxacin.
Gatifloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Gatifloxacin.
Norfloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Norfloxacin.
Levofloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Levofloxacin.
Gemifloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Gemifloxacin.
Ofloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Ofloxacin.
Sparfloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Sparfloxacin.
Temafloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Temafloxacin.
Fleroxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Fleroxacin.
Technetium Tc-99m ciprofloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Garenoxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Garenoxacin.
Nemonoxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Nemonoxacin.
Flumequine The therapeutic efficacy of Mitiglinide can be increased when used in combination with Flumequine.
Enrofloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Enrofloxacin.
Orbifloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Orbifloxacin.
Sarafloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Sarafloxacin.
Difloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Difloxacin.
Pazufloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Pazufloxacin.
Prulifloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Prulifloxacin.
Delafloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Delafloxacin.
Sitafloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Sitafloxacin.
Oxolinic acid The therapeutic efficacy of Mitiglinide can be increased when used in combination with Oxolinic acid.
Rufloxacin The therapeutic efficacy of Mitiglinide can be increased when used in combination with Rufloxacin.
Pipemidic acid The therapeutic efficacy of Mitiglinide can be increased when used in combination with Pipemidic acid.
Methyclothiazide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Methyclothiazide.
Chlorthalidone The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Chlorthalidone.
Bendroflumethiazide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Bendroflumethiazide.
Metolazone The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Metolazone.
Benzthiazide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Benzthiazide.
Hydroflumethiazide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Hydroflumethiazide.
Indapamide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Indapamide.
Chlorothiazide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Chlorothiazide.
Hydrochlorothiazide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Hydrochlorothiazide.
Trichlormethiazide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Trichlormethiazide.
Polythiazide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Polythiazide.
Quinethazone The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Quinethazone.
Cyclopenthiazide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Cyclopenthiazide.
Epitizide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Epitizide.
Amitriptyline Amitriptyline may decrease the hypoglycemic activities of Mitiglinide.
Protriptyline Protriptyline may decrease the hypoglycemic activities of Mitiglinide.
Imipramine Imipramine may decrease the hypoglycemic activities of Mitiglinide.
Nortriptyline Nortriptyline may decrease the hypoglycemic activities of Mitiglinide.
Amoxapine Amoxapine may decrease the hypoglycemic activities of Mitiglinide.
Trimipramine Trimipramine may decrease the hypoglycemic activities of Mitiglinide.
Doxepin Doxepin may decrease the hypoglycemic activities of Mitiglinide.
Desipramine Desipramine may decrease the hypoglycemic activities of Mitiglinide.
Clomipramine Clomipramine may decrease the hypoglycemic activities of Mitiglinide.
Amineptine Amineptine may decrease the hypoglycemic activities of Mitiglinide.
Dimetacrine Dimetacrine may decrease the hypoglycemic activities of Mitiglinide.
Butriptyline Butriptyline may decrease the hypoglycemic activities of Mitiglinide.
Dosulepin Dosulepin may decrease the hypoglycemic activities of Mitiglinide.
Tianeptine Tianeptine may decrease the hypoglycemic activities of Mitiglinide.
Oxaprotiline Oxaprotiline may decrease the hypoglycemic activities of Mitiglinide.
Opipramol Opipramol may decrease the hypoglycemic activities of Mitiglinide.
Amitriptylinoxide Amitriptylinoxide may decrease the hypoglycemic activities of Mitiglinide.
Dibenzepin Dibenzepin may decrease the hypoglycemic activities of Mitiglinide.
Quinupramine Quinupramine may decrease the hypoglycemic activities of Mitiglinide.
Melitracen Melitracen may decrease the hypoglycemic activities of Mitiglinide.
Lofepramine Lofepramine may decrease the hypoglycemic activities of Mitiglinide.
Iprindole Iprindole may decrease the hypoglycemic activities of Mitiglinide.
Imipramine oxide Imipramine oxide may decrease the hypoglycemic activities of Mitiglinide.
Dapagliflozin Dapagliflozin may increase the hypoglycemic activities of Mitiglinide.
Canagliflozin Canagliflozin may increase the hypoglycemic activities of Mitiglinide.
Leuprolide The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Leuprolide.
Goserelin The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Goserelin.
Nelfinavir The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Nelfinavir.
Indinavir The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Indinavir.
Ziprasidone The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Ziprasidone.
Etonogestrel The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Etonogestrel.
Desogestrel The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Desogestrel.
Olanzapine The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Olanzapine.
Megestrol acetate The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Megestrol acetate.
Clozapine The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Clozapine.
Levonorgestrel The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Levonorgestrel.
Progesterone The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Progesterone.
Chlorpromazine The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Chlorpromazine.
Haloperidol The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Haloperidol.
Ritonavir The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Ritonavir.
Piperazine The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Piperazine.
Medroxyprogesterone acetate The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Medroxyprogesterone acetate.
Niacin The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Niacin.
Epinephrine The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Epinephrine.
Norethisterone The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Norethisterone.
Risperidone The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Risperidone.
Pentamidine The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Pentamidine.
Ethynodiol diacetate The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Ethynodiol diacetate.
Pseudoephedrine The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Pseudoephedrine.
Tacrolimus The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Tacrolimus.
Sirolimus The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Sirolimus.

Target Protein

ATP-binding cassette sub-family C member 8 ABCC8
ATP-sensitive inward rectifier potassium channel 10 KCNJ10
Peroxisome proliferator-activated receptor gamma PPARG

Referensi & Sumber

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Contoh Produk & Brand

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International Brands
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Sekuens Gen/Protein (FASTA)

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