Gliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Pegvisomant | The risk or severity of hypoglycemia can be increased when Pegvisomant is combined with Gliquidone. |
| Carbocisteine | The risk or severity of adverse effects can be increased when Gliquidone is combined with Carbocisteine. |
| Chloramphenicol | The metabolism of Gliquidone can be decreased when combined with Chloramphenicol. |
| Cimetidine | The serum concentration of Gliquidone can be increased when it is combined with Cimetidine. |
| Fluconazole | The serum concentration of Gliquidone can be increased when it is combined with Fluconazole. |
| Metreleptin | Metreleptin may increase the hypoglycemic activities of Gliquidone. |
| Probenecid | The protein binding of Gliquidone can be decreased when combined with Probenecid. |
| Ranitidine | The serum concentration of Gliquidone can be increased when it is combined with Ranitidine. |
| Voriconazole | The serum concentration of Gliquidone can be increased when it is combined with Voriconazole. |
| Clarithromycin | The serum concentration of Gliquidone can be increased when it is combined with Clarithromycin. |
| Lipoic acid | The risk or severity of hypoglycemia can be increased when Lipoic acid is combined with Gliquidone. |
| Rifampin | The serum concentration of Gliquidone can be decreased when it is combined with Rifampicin. |
| Moxifloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Moxifloxacin. |
| Grepafloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Grepafloxacin. |
| Enoxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Enoxacin. |
| Pefloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Pefloxacin. |
| Ciprofloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Ciprofloxacin. |
| Trovafloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Trovafloxacin. |
| Nalidixic acid | The therapeutic efficacy of Gliquidone can be increased when used in combination with Nalidixic acid. |
| Rosoxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Rosoxacin. |
| Cinoxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Cinoxacin. |
| Lomefloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Lomefloxacin. |
| Gatifloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Gatifloxacin. |
| Norfloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Norfloxacin. |
| Levofloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Levofloxacin. |
| Gemifloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Gemifloxacin. |
| Ofloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Ofloxacin. |
| Sparfloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Sparfloxacin. |
| Temafloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Temafloxacin. |
| Fleroxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Fleroxacin. |
| Technetium Tc-99m ciprofloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Technetium Tc-99m ciprofloxacin. |
| Garenoxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Garenoxacin. |
| Nemonoxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Nemonoxacin. |
| Flumequine | The therapeutic efficacy of Gliquidone can be increased when used in combination with Flumequine. |
| Enrofloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Enrofloxacin. |
| Orbifloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Orbifloxacin. |
| Sarafloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Sarafloxacin. |
| Difloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Difloxacin. |
| Pazufloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Pazufloxacin. |
| Prulifloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Prulifloxacin. |
| Delafloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Delafloxacin. |
| Sitafloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Sitafloxacin. |
| Oxolinic acid | The therapeutic efficacy of Gliquidone can be increased when used in combination with Oxolinic acid. |
| Rufloxacin | The therapeutic efficacy of Gliquidone can be increased when used in combination with Rufloxacin. |
| Pipemidic acid | The therapeutic efficacy of Gliquidone can be increased when used in combination with Pipemidic acid. |
| Methyclothiazide | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Methyclothiazide. |
| Chlorthalidone | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Chlorthalidone. |
| Bendroflumethiazide | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Bendroflumethiazide. |
| Metolazone | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Metolazone. |
| Benzthiazide | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Benzthiazide. |
| Hydroflumethiazide | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Hydroflumethiazide. |
| Indapamide | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Indapamide. |
| Chlorothiazide | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Chlorothiazide. |
| Hydrochlorothiazide | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Hydrochlorothiazide. |
| Trichlormethiazide | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Trichlormethiazide. |
| Polythiazide | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Polythiazide. |
| Quinethazone | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Quinethazone. |
| Cyclopenthiazide | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Cyclopenthiazide. |
| Epitizide | The therapeutic efficacy of Gliquidone can be decreased when used in combination with Epitizide. |
| Esmolol | Esmolol may increase the hypoglycemic activities of Gliquidone. |
| Landiolol | Landiolol may increase the hypoglycemic activities of Gliquidone. |
| Ethanol | The risk or severity of adverse effects can be increased when Gliquidone is combined with Ethanol. |
| Amitriptyline | Amitriptyline may decrease the hypoglycemic activities of Gliquidone. |
| Protriptyline | Protriptyline may decrease the hypoglycemic activities of Gliquidone. |
| Imipramine | Imipramine may decrease the hypoglycemic activities of Gliquidone. |
| Nortriptyline | Nortriptyline may decrease the hypoglycemic activities of Gliquidone. |
| Amoxapine | Amoxapine may decrease the hypoglycemic activities of Gliquidone. |
| Desipramine | Desipramine may decrease the hypoglycemic activities of Gliquidone. |
| Clomipramine | Clomipramine may decrease the hypoglycemic activities of Gliquidone. |
| Amineptine | Amineptine may decrease the hypoglycemic activities of Gliquidone. |
| Dimetacrine | Dimetacrine may decrease the hypoglycemic activities of Gliquidone. |
| Butriptyline | Butriptyline may decrease the hypoglycemic activities of Gliquidone. |
| Dosulepin | Dosulepin may decrease the hypoglycemic activities of Gliquidone. |
| Tianeptine | Tianeptine may decrease the hypoglycemic activities of Gliquidone. |
| Oxaprotiline | Oxaprotiline may decrease the hypoglycemic activities of Gliquidone. |
| Opipramol | Opipramol may decrease the hypoglycemic activities of Gliquidone. |
| Amitriptylinoxide | Amitriptylinoxide may decrease the hypoglycemic activities of Gliquidone. |
| Dibenzepin | Dibenzepin may decrease the hypoglycemic activities of Gliquidone. |
| Quinupramine | Quinupramine may decrease the hypoglycemic activities of Gliquidone. |
| Melitracen | Melitracen may decrease the hypoglycemic activities of Gliquidone. |
| Lofepramine | Lofepramine may decrease the hypoglycemic activities of Gliquidone. |
| Iprindole | Iprindole may decrease the hypoglycemic activities of Gliquidone. |
| Imipramine oxide | Imipramine oxide may decrease the hypoglycemic activities of Gliquidone. |
| Doxepin | Doxepin may decrease the hypoglycemic activities of Gliquidone. |
| Clofibrate | The risk or severity of hypoglycemia can be increased when Clofibrate is combined with Gliquidone. |
| Fenofibrate | The risk or severity of hypoglycemia can be increased when Fenofibrate is combined with Gliquidone. |
| Bezafibrate | The risk or severity of hypoglycemia can be increased when Bezafibrate is combined with Gliquidone. |
| Etofibrate | The risk or severity of hypoglycemia can be increased when Etofibrate is combined with Gliquidone. |
| Ciprofibrate | The risk or severity of hypoglycemia can be increased when Ciprofibrate is combined with Gliquidone. |
| Simfibrate | The risk or severity of hypoglycemia can be increased when Simfibrate is combined with Gliquidone. |
| Ronifibrate | The risk or severity of hypoglycemia can be increased when Ronifibrate is combined with Gliquidone. |
| Aluminium clofibrate | The risk or severity of hypoglycemia can be increased when Aluminium clofibrate is combined with Gliquidone. |
| Clofibride | The risk or severity of hypoglycemia can be increased when Clofibride is combined with Gliquidone. |
| Fenofibric acid | The risk or severity of hypoglycemia can be increased when Fenofibric acid is combined with Gliquidone. |
| Miconazole | The serum concentration of Gliquidone can be increased when it is combined with Miconazole. |
| Phenindione | Gliquidone may increase the anticoagulant activities of Phenindione. |
| Coumarin | Gliquidone may increase the anticoagulant activities of Coumarin. |
| (R)-warfarin | Gliquidone may increase the anticoagulant activities of (R)-warfarin. |
| Clorindione | Gliquidone may increase the anticoagulant activities of Clorindione. |
| Diphenadione | Gliquidone may increase the anticoagulant activities of Diphenadione. |