Peringatan Keamanan

Signs of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, swelling of face, lips, tongue, or throat.

Bromodiphenhydramine

DB01237

small molecule approved

Deskripsi

Bromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.

Struktur Molekul 2D

Berat 334.251
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 1 to 4 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Well absorbed in the digestive tract.

Metabolisme

Hepatic (cytochrome P-450 system); some renal.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

36 Data
Hyoscyamine Bromodiphenhydramine may increase the anticholinergic activities of Hyoscyamine.
Benzylpenicilloyl polylysine Bromodiphenhydramine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent.
Betahistine The therapeutic efficacy of Betahistine can be decreased when used in combination with Bromodiphenhydramine.
Amphetamine Amphetamine may decrease the sedative activities of Bromodiphenhydramine.
Phentermine Phentermine may decrease the sedative activities of Bromodiphenhydramine.
Pseudoephedrine Pseudoephedrine may decrease the sedative activities of Bromodiphenhydramine.
Benzphetamine Benzphetamine may decrease the sedative activities of Bromodiphenhydramine.
Diethylpropion Diethylpropion may decrease the sedative activities of Bromodiphenhydramine.
Lisdexamfetamine Lisdexamfetamine may decrease the sedative activities of Bromodiphenhydramine.
Mephentermine Mephentermine may decrease the sedative activities of Bromodiphenhydramine.
MMDA MMDA may decrease the sedative activities of Bromodiphenhydramine.
Midomafetamine Midomafetamine may decrease the sedative activities of Bromodiphenhydramine.
2,5-Dimethoxy-4-ethylamphetamine 2,5-Dimethoxy-4-ethylamphetamine may decrease the sedative activities of Bromodiphenhydramine.
4-Bromo-2,5-dimethoxyamphetamine 4-Bromo-2,5-dimethoxyamphetamine may decrease the sedative activities of Bromodiphenhydramine.
Tenamfetamine Tenamfetamine may decrease the sedative activities of Bromodiphenhydramine.
Chlorphentermine Chlorphentermine may decrease the sedative activities of Bromodiphenhydramine.
Methylenedioxyethamphetamine Methylenedioxyethamphetamine may decrease the sedative activities of Bromodiphenhydramine.
Dextroamphetamine Dextroamphetamine may decrease the sedative activities of Bromodiphenhydramine.
Metamfetamine Metamfetamine may decrease the sedative activities of Bromodiphenhydramine.
Phendimetrazine Phendimetrazine may decrease the sedative activities of Bromodiphenhydramine.
Iofetamine I-123 Iofetamine I-123 may decrease the sedative activities of Bromodiphenhydramine.
Ritobegron Ritobegron may decrease the sedative activities of Bromodiphenhydramine.
Mephedrone Mephedrone may decrease the sedative activities of Bromodiphenhydramine.
Methoxyphenamine Methoxyphenamine may decrease the sedative activities of Bromodiphenhydramine.
Gepefrine Gepefrine may decrease the sedative activities of Bromodiphenhydramine.
2,5-Dimethoxy-4-ethylthioamphetamine 2,5-Dimethoxy-4-ethylthioamphetamine may decrease the sedative activities of Bromodiphenhydramine.
Pitolisant The therapeutic efficacy of Pitolisant can be decreased when used in combination with Bromodiphenhydramine.
Norepinephrine The therapeutic efficacy of Norepinephrine can be increased when used in combination with Bromodiphenhydramine.
Epinephrine The therapeutic efficacy of Epinephrine can be increased when used in combination with Bromodiphenhydramine.
Ephedrine The therapeutic efficacy of Ephedrine can be increased when used in combination with Bromodiphenhydramine.
Droxidopa The therapeutic efficacy of Droxidopa can be increased when used in combination with Bromodiphenhydramine.
Levonordefrin The therapeutic efficacy of Levonordefrin can be increased when used in combination with Bromodiphenhydramine.
Protokylol The therapeutic efficacy of Protokylol can be increased when used in combination with Bromodiphenhydramine.
Racepinephrine The therapeutic efficacy of Racepinephrine can be increased when used in combination with Bromodiphenhydramine.
Theodrenaline The therapeutic efficacy of Theodrenaline can be increased when used in combination with Bromodiphenhydramine.
Deoxyepinephrine The therapeutic efficacy of Deoxyepinephrine can be increased when used in combination with Bromodiphenhydramine.

Target Protein

Histamine H1 receptor HRH1

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 2 • International brands: 0
Produk
  • Ambenyl Cough Syrup
    Liquid • - • Oral • Canada • Approved
  • Diphenhydramine HCI and Zinc Acetate
    Aerosol, spray • - • Topical • US • OTC

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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