Encainide

DB01228

small molecule approved investigational withdrawn

Deskripsi

All drug products containing encainide hydrochloride. Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.

Struktur Molekul 2D

Berat 352.4699
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 1-2 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

A radiolabeled dose of encainide is excreted in approximately equal amounts in the urine and feces.

Interaksi Obat

656 Data
Mirabegron The serum concentration of Encainide can be increased when it is combined with Mirabegron.
Nisoldipine Nisoldipine may increase the arrhythmogenic activities of Encainide.
Acetyldigitoxin Acetyldigitoxin may increase the arrhythmogenic activities of Encainide.
Magnesium sulfate Magnesium sulfate may increase the arrhythmogenic activities of Encainide.
Tocainide Tocainide may increase the arrhythmogenic activities of Encainide.
Deslanoside Deslanoside may increase the arrhythmogenic activities of Encainide.
Carteolol Encainide may increase the arrhythmogenic activities of Carteolol.
Metipranolol Encainide may increase the arrhythmogenic activities of Metipranolol.
Dexpropranolol Encainide may increase the arrhythmogenic activities of Dexpropranolol.
Nimesulide Encainide may increase the arrhythmogenic activities of Nimesulide.
Cyclandelate Encainide may increase the arrhythmogenic activities of Cyclandelate.
Seletracetam Encainide may increase the arrhythmogenic activities of Seletracetam.
Nylidrin Encainide may increase the arrhythmogenic activities of Nylidrin.
Dotarizine Encainide may increase the arrhythmogenic activities of Dotarizine.
Xylometazoline Encainide may increase the arrhythmogenic activities of Xylometazoline.
Tranilast Encainide may increase the arrhythmogenic activities of Tranilast.
Fasudil Encainide may increase the arrhythmogenic activities of Fasudil.
Agmatine Encainide may increase the arrhythmogenic activities of Agmatine.
Nicorandil Encainide may increase the arrhythmogenic activities of Nicorandil.
Barnidipine Encainide may increase the arrhythmogenic activities of Barnidipine.
Azelnidipine Encainide may increase the arrhythmogenic activities of Azelnidipine.
Cilnidipine Encainide may increase the arrhythmogenic activities of Cilnidipine.
Darodipine Encainide may increase the arrhythmogenic activities of Darodipine.
Niludipine Encainide may increase the arrhythmogenic activities of Niludipine.
Tropisetron Encainide may increase the arrhythmogenic activities of Tropisetron.
Carboxyamidotriazole Encainide may increase the arrhythmogenic activities of Carboxyamidotriazole.
Naftopidil Encainide may increase the arrhythmogenic activities of Naftopidil.
Vinpocetine Encainide may increase the arrhythmogenic activities of Vinpocetine.
Spiradoline Encainide may increase the arrhythmogenic activities of Spiradoline.
Cymarin Encainide may increase the arrhythmogenic activities of Cymarin.
Metildigoxin Encainide may increase the arrhythmogenic activities of Metildigoxin.
Tiracizine Encainide may increase the arrhythmogenic activities of Tiracizine.
Ethacizine Encainide may increase the arrhythmogenic activities of Ethacizine.
Hydroquinine Encainide may increase the arrhythmogenic activities of Hydroquinine.
Bioallethrin Encainide may increase the arrhythmogenic activities of Bioallethrin.
Caroverine Encainide may increase the arrhythmogenic activities of Caroverine.
Fosfructose Encainide may increase the arrhythmogenic activities of Fosfructose.
WIN 55212-2 Encainide may increase the arrhythmogenic activities of WIN 55212-2.
Fish oil Encainide may increase the arrhythmogenic activities of Fish oil.
Emopamil Encainide may increase the arrhythmogenic activities of Emopamil.
Lomerizine Encainide may increase the arrhythmogenic activities of Lomerizine.
Tetrandrine Encainide may increase the arrhythmogenic activities of Tetrandrine.
Dexniguldipine Encainide may increase the arrhythmogenic activities of Dexniguldipine.
Fosinoprilat Encainide may increase the arrhythmogenic activities of Fosinoprilat.
Hydroquinidine Encainide may increase the arrhythmogenic activities of Hydroquinidine.
SOR-C13 Encainide may increase the arrhythmogenic activities of SOR-C13.
Betaxolol Betaxolol may increase the arrhythmogenic activities of Encainide.
Diltiazem Diltiazem may increase the arrhythmogenic activities of Encainide.
Nimodipine Nimodipine may increase the arrhythmogenic activities of Encainide.
Cinnarizine Cinnarizine may increase the arrhythmogenic activities of Encainide.
Propranolol Propranolol may increase the arrhythmogenic activities of Encainide.
Atropine Atropine may increase the arrhythmogenic activities of Encainide.
Adenosine Adenosine may increase the arrhythmogenic activities of Encainide.
Loperamide Loperamide may increase the arrhythmogenic activities of Encainide.
Levosimendan Levosimendan may increase the arrhythmogenic activities of Encainide.
Nifedipine Nifedipine may increase the arrhythmogenic activities of Encainide.
Acebutolol Acebutolol may increase the arrhythmogenic activities of Encainide.
Mibefradil Encainide may increase the arrhythmogenic activities of Mibefradil.
Oxprenolol Encainide may increase the arrhythmogenic activities of Oxprenolol.
Prenylamine Encainide may increase the arrhythmogenic activities of Prenylamine.
Fluspirilene Encainide may increase the arrhythmogenic activities of Fluspirilene.
Azimilide Encainide may increase the arrhythmogenic activities of Azimilide.
Tedisamil Encainide may increase the arrhythmogenic activities of Tedisamil.
Nilvadipine Encainide may increase the arrhythmogenic activities of Nilvadipine.
Indenolol Encainide may increase the arrhythmogenic activities of Indenolol.
Fendiline Encainide may increase the arrhythmogenic activities of Fendiline.
Eperisone Encainide may increase the arrhythmogenic activities of Eperisone.
Melperone Encainide may increase the arrhythmogenic activities of Melperone.
Benidipine Encainide may increase the arrhythmogenic activities of Benidipine.
Simendan Encainide may increase the arrhythmogenic activities of Simendan.
Otilonium Encainide may increase the arrhythmogenic activities of Otilonium.
Nizofenone Encainide may increase the arrhythmogenic activities of Nizofenone.
Bunaftine Encainide may increase the arrhythmogenic activities of Bunaftine.
Lorcainide Encainide may increase the arrhythmogenic activities of Lorcainide.
Penfluridol Encainide may increase the arrhythmogenic activities of Penfluridol.
Dexverapamil Encainide may increase the arrhythmogenic activities of Dexverapamil.
Dofetilide Dofetilide may increase the arrhythmogenic activities of Encainide.
Disopyramide Disopyramide may increase the arrhythmogenic activities of Encainide.
Ibutilide Ibutilide may increase the arrhythmogenic activities of Encainide.
Quinidine Quinidine may increase the arrhythmogenic activities of Encainide.
Bepridil Encainide may increase the arrhythmogenic activities of Bepridil.
Terodiline Encainide may increase the arrhythmogenic activities of Terodiline.
Esmolol Esmolol may increase the arrhythmogenic activities of Encainide.
Isradipine Isradipine may increase the arrhythmogenic activities of Encainide.
Trimethadione Trimethadione may increase the arrhythmogenic activities of Encainide.
Timolol Timolol may increase the arrhythmogenic activities of Encainide.
Amlodipine Amlodipine may increase the arrhythmogenic activities of Encainide.
Digoxin Digoxin may increase the arrhythmogenic activities of Encainide.
Hyoscyamine Hyoscyamine may increase the arrhythmogenic activities of Encainide.
Lamotrigine Lamotrigine may increase the arrhythmogenic activities of Encainide.
Ethosuximide Ethosuximide may increase the arrhythmogenic activities of Encainide.
Verapamil Verapamil may increase the arrhythmogenic activities of Encainide.
Losartan Losartan may increase the arrhythmogenic activities of Encainide.
Moricizine Moricizine may increase the arrhythmogenic activities of Encainide.
Levomenthol Levomenthol may increase the arrhythmogenic activities of Encainide.
Zonisamide Zonisamide may increase the arrhythmogenic activities of Encainide.
Felodipine Felodipine may increase the arrhythmogenic activities of Encainide.
Nitrendipine Nitrendipine may increase the arrhythmogenic activities of Encainide.
Bretylium Bretylium may increase the arrhythmogenic activities of Encainide.
Digitoxin Encainide may increase the arrhythmogenic activities of Digitoxin.

Target Protein

Sodium channel protein type 5 subunit alpha SCN5A

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 2 • International brands: 0
Produk
  • Enkaid
    Capsule, gelatin coated • 25 mg/1 • Oral • US • Approved
  • Enkaid
    Capsule, gelatin coated • 35 mg/1 • Oral • US • Approved

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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