Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Aripiprazole | The metabolism of Aripiprazole can be increased when combined with Rifapentine. |
| Aripiprazole lauroxil | The serum concentration of aripiprazole, an active metabolite of Rifapentine, can be decreased when used in combination with Aripiprazole lauroxil. |
| Clopidogrel | The therapeutic efficacy of Clopidogrel can be increased when used in combination with Rifapentine. |
| Ifosfamide | The metabolism of Ifosfamide can be increased when combined with Rifapentine. |
| Isoniazid | Rifapentine may increase the hepatotoxic activities of Isoniazid. |
| Perampanel | The metabolism of Perampanel can be increased when combined with Rifapentine. |
| Warfarin | The metabolism of Warfarin can be increased when combined with Rifapentine. |
| Acenocoumarol | The metabolism of Acenocoumarol can be increased when combined with Rifapentine. |
| (R)-warfarin | The metabolism of (R)-warfarin can be increased when combined with Rifapentine. |
| R,S-Warfarin alcohol | The metabolism of R,S-Warfarin alcohol can be increased when combined with Rifapentine. |
| S,R-Warfarin alcohol | The metabolism of S,R-Warfarin alcohol can be increased when combined with Rifapentine. |
| (S)-Warfarin | The metabolism of (S)-Warfarin can be increased when combined with Rifapentine. |
| Mycophenolate mofetil | The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Rifapentine. |
| Mycophenolic acid | The serum concentration of Mycophenolic acid can be decreased when it is combined with Rifapentine. |
| Picosulfuric acid | The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Rifapentine. |
| Erlotinib | The metabolism of Erlotinib can be increased when combined with Rifapentine. |
| BCG vaccine | The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Rifapentine. |
| Typhoid vaccine | The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Rifapentine. |
| Esmolol | The metabolism of Esmolol can be increased when combined with Rifapentine. |
| Betaxolol | The metabolism of Betaxolol can be increased when combined with Rifapentine. |
| Metoprolol | The metabolism of Metoprolol can be increased when combined with Rifapentine. |
| Atenolol | The metabolism of Atenolol can be increased when combined with Rifapentine. |
| Timolol | The metabolism of Timolol can be increased when combined with Rifapentine. |
| Sotalol | The metabolism of Sotalol can be increased when combined with Rifapentine. |
| Labetalol | The metabolism of Labetalol can be increased when combined with Rifapentine. |
| Bisoprolol | The metabolism of Bisoprolol can be increased when combined with Rifapentine. |
| Alprenolol | The metabolism of Alprenolol can be increased when combined with Rifapentine. |
| Pindolol | The metabolism of Pindolol can be increased when combined with Rifapentine. |
| Carvedilol | The metabolism of Carvedilol can be increased when combined with Rifapentine. |
| Propafenone | The metabolism of Propafenone can be increased when combined with Rifapentine. |
| Acebutolol | The metabolism of Acebutolol can be increased when combined with Rifapentine. |
| Nadolol | The metabolism of Nadolol can be increased when combined with Rifapentine. |
| Bevantolol | The metabolism of Bevantolol can be increased when combined with Rifapentine. |
| Practolol | The metabolism of Practolol can be increased when combined with Rifapentine. |
| Penbutolol | The metabolism of Penbutolol can be increased when combined with Rifapentine. |
| Oxprenolol | The metabolism of Oxprenolol can be increased when combined with Rifapentine. |
| Dexpropranolol | The metabolism of Dexpropranolol can be increased when combined with Rifapentine. |
| Celiprolol | The metabolism of Celiprolol can be increased when combined with Rifapentine. |
| Nebivolol | The metabolism of Nebivolol can be increased when combined with Rifapentine. |
| Bufuralol | The metabolism of Bufuralol can be increased when combined with Rifapentine. |
| Bopindolol | The metabolism of Bopindolol can be increased when combined with Rifapentine. |
| Bupranolol | The metabolism of Bupranolol can be increased when combined with Rifapentine. |
| Indenolol | The metabolism of Indenolol can be increased when combined with Rifapentine. |
| Arotinolol | The metabolism of Arotinolol can be increased when combined with Rifapentine. |
| Levobetaxolol | The metabolism of Levobetaxolol can be increased when combined with Rifapentine. |
| Talinolol | The metabolism of Talinolol can be increased when combined with Rifapentine. |
| Anisodamine | The metabolism of Anisodamine can be increased when combined with Rifapentine. |
| Bucindolol | The metabolism of Bucindolol can be increased when combined with Rifapentine. |
| Esatenolol | The metabolism of Esatenolol can be increased when combined with Rifapentine. |
| Cloranolol | The metabolism of Cloranolol can be increased when combined with Rifapentine. |
| Mepindolol | The metabolism of Mepindolol can be increased when combined with Rifapentine. |
| Epanolol | The metabolism of Epanolol can be increased when combined with Rifapentine. |
| Tertatolol | The metabolism of Tertatolol can be increased when combined with Rifapentine. |
| Landiolol | The metabolism of Landiolol can be increased when combined with Rifapentine. |
| Pitolisant | The metabolism of Pitolisant can be increased when combined with Rifapentine. |
| Segesterone acetate | The metabolism of Segesterone acetate can be increased when combined with Rifapentine. |
| Metreleptin | The metabolism of Rifapentine can be increased when combined with Metreleptin. |
| Diethylstilbestrol | The metabolism of Diethylstilbestrol can be increased when combined with Rifapentine. |
| Etonogestrel | The metabolism of Etonogestrel can be increased when combined with Rifapentine. |
| Megestrol acetate | The metabolism of Megestrol acetate can be increased when combined with Rifapentine. |
| Levonorgestrel | The metabolism of Levonorgestrel can be increased when combined with Rifapentine. |
| Medroxyprogesterone acetate | The metabolism of Medroxyprogesterone acetate can be increased when combined with Rifapentine. |
| Norethisterone | The metabolism of Norethisterone can be increased when combined with Rifapentine. |
| Ethynodiol diacetate | The metabolism of Ethynodiol diacetate can be increased when combined with Rifapentine. |
| Mifepristone | The metabolism of Mifepristone can be increased when combined with Rifapentine. |
| Norgestimate | The metabolism of Norgestimate can be increased when combined with Rifapentine. |
| Ethinylestradiol | The metabolism of Ethinylestradiol can be increased when combined with Rifapentine. |
| Drospirenone | The metabolism of Drospirenone can be increased when combined with Rifapentine. |
| Octylphenoxy polyethoxyethanol | The metabolism of Octylphenoxy polyethoxyethanol can be increased when combined with Rifapentine. |
| Cyproterone acetate | The metabolism of Cyproterone acetate can be increased when combined with Rifapentine. |
| Trestolone | The metabolism of Trestolone can be increased when combined with Rifapentine. |
| Norelgestromin | The metabolism of Norelgestromin can be increased when combined with Rifapentine. |
| Gestodene | The metabolism of Gestodene can be increased when combined with Rifapentine. |
| Hydroxyprogesterone caproate | The metabolism of Hydroxyprogesterone caproate can be increased when combined with Rifapentine. |
| Dienogest | The metabolism of Dienogest can be increased when combined with Rifapentine. |
| Norethynodrel | The metabolism of Norethynodrel can be increased when combined with Rifapentine. |
| Norgestrel | The metabolism of Norgestrel can be increased when combined with Rifapentine. |
| Cloprostenol | The metabolism of Cloprostenol can be increased when combined with Rifapentine. |
| Gestrinone | The metabolism of Gestrinone can be increased when combined with Rifapentine. |
| Nomegestrol | The metabolism of Nomegestrol can be increased when combined with Rifapentine. |
| Gossypol | The metabolism of Gossypol can be increased when combined with Rifapentine. |
| Ormeloxifene | The metabolism of Ormeloxifene can be increased when combined with Rifapentine. |
| Chlormadinone | The metabolism of Chlormadinone can be increased when combined with Rifapentine. |
| Norgestrienone | The metabolism of Norgestrienone can be increased when combined with Rifapentine. |
| Quingestanol | The metabolism of Quingestanol can be increased when combined with Rifapentine. |
| Demegestone | The metabolism of Demegestone can be increased when combined with Rifapentine. |
| Etynodiol | The metabolism of Etynodiol can be increased when combined with Rifapentine. |
| Nomegestrol acetate | The metabolism of Nomegestrol acetate can be increased when combined with Rifapentine. |
| Norethindrone enanthate | The metabolism of Norethindrone enanthate can be increased when combined with Rifapentine. |
| Desogestrel | The metabolism of Desogestrel can be increased when combined with Rifapentine. |
| Mestranol | The metabolism of Mestranol can be increased when combined with Rifapentine. |
| Estrone sulfate | The metabolism of Estrone sulfate can be increased when combined with Rifapentine. |
| Ulipristal | The metabolism of Ulipristal can be increased when combined with Rifapentine. |
| Testosterone enanthate | The metabolism of Testosterone enanthate can be increased when combined with Rifapentine. |
| Estradiol benzoate | The metabolism of Estradiol benzoate can be increased when combined with Rifapentine. |
| Estradiol cypionate | The metabolism of Estradiol cypionate can be increased when combined with Rifapentine. |
| Estradiol valerate | The metabolism of Estradiol valerate can be increased when combined with Rifapentine. |
| Phenindione | The risk or severity of bleeding can be increased when Rifapentine is combined with Phenindione. |
| Coumarin | The risk or severity of bleeding can be increased when Rifapentine is combined with Coumarin. |
| Tioclomarol | The risk or severity of bleeding can be increased when Rifapentine is combined with Tioclomarol. |