Side effects include drowsiness, dizziness, tiredness or confusion. LD50=1000 mg/kg (mouse, oral)
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. PubChem
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Alfuzosin | Alfuzosin may increase the hypotensive activities of Guanethidine. |
| Amifostine | Guanethidine may increase the hypotensive activities of Amifostine. |
| Diazoxide | Diazoxide may increase the hypotensive activities of Guanethidine. |
| Methylphenidate | Methylphenidate may decrease the antihypertensive activities of Guanethidine. |
| Dexmethylphenidate | Dexmethylphenidate may decrease the antihypertensive activities of Guanethidine. |
| Obinutuzumab | Guanethidine may increase the hypotensive activities of Obinutuzumab. |
| Pentoxifylline | Pentoxifylline may increase the hypotensive activities of Guanethidine. |
| Rituximab | Guanethidine may increase the hypotensive activities of Rituximab. |
| Zolmitriptan | Zolmitriptan may decrease the antihypertensive activities of Guanethidine. |
| Protriptyline | Protriptyline may decrease the antihypertensive activities of Guanethidine. |
| Droperidol | Droperidol may decrease the antihypertensive activities of Guanethidine. |
| Amoxapine | Amoxapine may decrease the antihypertensive activities of Guanethidine. |
| Doxapram | Doxapram may decrease the antihypertensive activities of Guanethidine. |
| Atropine | Atropine may decrease the antihypertensive activities of Guanethidine. |
| Nicergoline | Nicergoline may decrease the antihypertensive activities of Guanethidine. |
| Propiomazine | Propiomazine may decrease the antihypertensive activities of Guanethidine. |
| Phenmetrazine | Phenmetrazine may decrease the antihypertensive activities of Guanethidine. |
| Trifluoperazine | Trifluoperazine may decrease the antihypertensive activities of Guanethidine. |
| Naratriptan | Naratriptan may decrease the antihypertensive activities of Guanethidine. |
| Frovatriptan | Frovatriptan may decrease the antihypertensive activities of Guanethidine. |
| Methotrimeprazine | Methotrimeprazine may decrease the antihypertensive activities of Guanethidine. |
| Periciazine | Periciazine may decrease the antihypertensive activities of Guanethidine. |
| Acepromazine | Acepromazine may decrease the antihypertensive activities of Guanethidine. |
| Thioproperazine | Thioproperazine may decrease the antihypertensive activities of Guanethidine. |
| Epicaptopril | Epicaptopril may decrease the antihypertensive activities of Guanethidine. |
| 1-benzylimidazole | 1-benzylimidazole may decrease the antihypertensive activities of Guanethidine. |
| Amineptine | Amineptine may decrease the antihypertensive activities of Guanethidine. |
| Naluzotan | Naluzotan may decrease the antihypertensive activities of Guanethidine. |
| Pizotifen | Pizotifen may decrease the antihypertensive activities of Guanethidine. |
| Esmirtazapine | Esmirtazapine may decrease the antihypertensive activities of Guanethidine. |
| Nitrous oxide | Nitrous oxide may decrease the antihypertensive activities of Guanethidine. |
| Saralasin | Saralasin may decrease the antihypertensive activities of Guanethidine. |
| Cinitapride | Cinitapride may decrease the antihypertensive activities of Guanethidine. |
| Tyramine | Tyramine may decrease the antihypertensive activities of Guanethidine. |
| Ifenprodil | Ifenprodil may decrease the antihypertensive activities of Guanethidine. |
| Butriptyline | Butriptyline may decrease the antihypertensive activities of Guanethidine. |
| Dosulepin | Dosulepin may decrease the antihypertensive activities of Guanethidine. |
| Oxaprotiline | Oxaprotiline may decrease the antihypertensive activities of Guanethidine. |
| Atipamezole | Atipamezole may decrease the antihypertensive activities of Guanethidine. |
| Tetrahydrocannabivarin | Tetrahydrocannabivarin may decrease the antihypertensive activities of Guanethidine. |
| Piclozotan | Piclozotan may decrease the antihypertensive activities of Guanethidine. |
| Idazoxan | Idazoxan may decrease the antihypertensive activities of Guanethidine. |
| Theodrenaline | Theodrenaline may decrease the antihypertensive activities of Guanethidine. |
| Opipramol | Opipramol may decrease the antihypertensive activities of Guanethidine. |
| Tramazoline | Tramazoline may decrease the antihypertensive activities of Guanethidine. |
| Amitriptylinoxide | Amitriptylinoxide may decrease the antihypertensive activities of Guanethidine. |
| Dibenzepin | Dibenzepin may decrease the antihypertensive activities of Guanethidine. |
| Quinupramine | Quinupramine may decrease the antihypertensive activities of Guanethidine. |
| Trichloroethylene | Trichloroethylene may decrease the antihypertensive activities of Guanethidine. |
| Fenozolone | Fenozolone may decrease the antihypertensive activities of Guanethidine. |
| Melitracen | Melitracen may decrease the antihypertensive activities of Guanethidine. |
| Lofepramine | Lofepramine may decrease the antihypertensive activities of Guanethidine. |
| Xenon | Xenon may decrease the antihypertensive activities of Guanethidine. |
| Iprindole | Iprindole may decrease the antihypertensive activities of Guanethidine. |
| Buflomedil | Buflomedil may decrease the antihypertensive activities of Guanethidine. |
| Metergoline | Metergoline may decrease the antihypertensive activities of Guanethidine. |
| Diethyl ether | Diethyl ether may decrease the antihypertensive activities of Guanethidine. |
| Imipramine oxide | Imipramine oxide may decrease the antihypertensive activities of Guanethidine. |
| Mefenorex | Mefenorex may decrease the antihypertensive activities of Guanethidine. |
| Deoxyepinephrine | Deoxyepinephrine may decrease the antihypertensive activities of Guanethidine. |
| 5-methoxy-N,N-dimethyltryptamine | 5-methoxy-N,N-dimethyltryptamine may decrease the antihypertensive activities of Guanethidine. |
| Quinoline Yellow WS | Quinoline Yellow WS may decrease the antihypertensive activities of Guanethidine. |
| Thioridazine | Thioridazine may decrease the antihypertensive activities of Guanethidine. |
| Isoflurane | Isoflurane may decrease the antihypertensive activities of Guanethidine. |
| Tolazoline | Tolazoline may decrease the antihypertensive activities of Guanethidine. |
| Propofol | Propofol may decrease the antihypertensive activities of Guanethidine. |
| Remifentanil | Remifentanil may decrease the antihypertensive activities of Guanethidine. |
| Phenoxybenzamine | Phenoxybenzamine may decrease the antihypertensive activities of Guanethidine. |
| Desflurane | Desflurane may decrease the antihypertensive activities of Guanethidine. |
| Isoxsuprine | Isoxsuprine may decrease the antihypertensive activities of Guanethidine. |
| Indoramin | Indoramin may decrease the antihypertensive activities of Guanethidine. |
| Moxonidine | Moxonidine may decrease the antihypertensive activities of Guanethidine. |
| Trimipramine | Trimipramine may decrease the antihypertensive activities of Guanethidine. |
| Dutasteride | Dutasteride may decrease the antihypertensive activities of Guanethidine. |
| Sufentanil | Sufentanil may decrease the antihypertensive activities of Guanethidine. |
| Halothane | Halothane may decrease the antihypertensive activities of Guanethidine. |
| Bromocriptine | Bromocriptine may decrease the antihypertensive activities of Guanethidine. |
| Sevoflurane | Sevoflurane may decrease the antihypertensive activities of Guanethidine. |
| Rotigotine | Rotigotine may decrease the antihypertensive activities of Guanethidine. |
| Eletriptan | Eletriptan may decrease the antihypertensive activities of Guanethidine. |
| Methysergide | Methysergide may decrease the antihypertensive activities of Guanethidine. |
| Cabergoline | Cabergoline may decrease the antihypertensive activities of Guanethidine. |
| Dihydroergotamine | Dihydroergotamine may decrease the antihypertensive activities of Guanethidine. |
| Methylergometrine | Methylergometrine may decrease the antihypertensive activities of Guanethidine. |
| Mirtazapine | Mirtazapine may decrease the antihypertensive activities of Guanethidine. |
| Promazine | Promazine may decrease the antihypertensive activities of Guanethidine. |
| Nortriptyline | Nortriptyline may decrease the antihypertensive activities of Guanethidine. |
| Lisuride | Lisuride may decrease the antihypertensive activities of Guanethidine. |
| Trazodone | Trazodone may decrease the antihypertensive activities of Guanethidine. |
| Ergotamine | Ergotamine may decrease the antihypertensive activities of Guanethidine. |
| Risperidone | Risperidone may decrease the antihypertensive activities of Guanethidine. |
| Alfentanil | Alfentanil may decrease the antihypertensive activities of Guanethidine. |
| Methoxyflurane | Methoxyflurane may decrease the antihypertensive activities of Guanethidine. |
| Ergoloid mesylate | Ergoloid mesylate may decrease the antihypertensive activities of Guanethidine. |
| Finasteride | Finasteride may decrease the antihypertensive activities of Guanethidine. |
| Yohimbine | Yohimbine may decrease the antihypertensive activities of Guanethidine. |
| Solifenacin | Solifenacin may decrease the antihypertensive activities of Guanethidine. |
| Zuclopenthixol | Zuclopenthixol may decrease the antihypertensive activities of Guanethidine. |
| Lysergic acid diethylamide | Lysergic acid diethylamide may decrease the antihypertensive activities of Guanethidine. |
| Dronedarone | Dronedarone may decrease the antihypertensive activities of Guanethidine. |