Intravenous LD50 in rat is 51 mg/kg.
A barbiturate that is administered intravenously for the production of complete anesthesia of short duration, for the induction of general anesthesia, or for inducing a hypnotic state. (From Martindale, The Extra Pharmacopoeia, 30th ed, p919)
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Buprenorphine | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Thiamylal. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Thiamylal. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Thiamylal. |
| Hydrocodone | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Thiamylal. |
| Magnesium sulfate | The therapeutic efficacy of Thiamylal can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Metyrosine | Thiamylal may increase the sedative activities of Metyrosine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Thiamylal. |
| Mirtazapine | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Thiamylal. |
| Orphenadrine | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Thiamylal. |
| Pramipexole | Thiamylal may increase the sedative activities of Pramipexole. |
| Ropinirole | Thiamylal may increase the sedative activities of Ropinirole. |
| Rotigotine | Thiamylal may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Thiamylal. |
| Suvorexant | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Thiamylal. |
| Thalidomide | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Mefloquine | The therapeutic efficacy of Thiamylal can be decreased when used in combination with Mefloquine. |
| Orlistat | Orlistat can cause a decrease in the absorption of Thiamylal resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Acetaminophen | The metabolism of Acetaminophen can be increased when combined with Thiamylal. |
| Propacetamol | The metabolism of Propacetamol can be increased when combined with Thiamylal. |
| Chloramphenicol | The metabolism of Thiamylal can be decreased when combined with Chloramphenicol. |
| Doxycycline | The serum concentration of Doxycycline can be decreased when it is combined with Thiamylal. |
| Felbamate | The serum concentration of Thiamylal can be increased when it is combined with Felbamate. |
| Griseofulvin | The serum concentration of Griseofulvin can be decreased when it is combined with Thiamylal. |
| Lamotrigine | The serum concentration of Lamotrigine can be decreased when it is combined with Thiamylal. |
| Mianserin | The therapeutic efficacy of Thiamylal can be decreased when used in combination with Mianserin. |
| Methylphenobarbital | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Thiamylal. |
| Pyridoxine | The metabolism of Thiamylal can be increased when combined with Pyridoxine. |
| Teniposide | The serum concentration of Teniposide can be decreased when it is combined with Thiamylal. |
| Ulipristal | The serum concentration of Ulipristal can be decreased when it is combined with Thiamylal. |
| Voriconazole | The serum concentration of Voriconazole can be decreased when it is combined with Thiamylal. |
| Topotecan | Thiamylal may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Thiamylal. |
| Sodium oxybate | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Tetracosactide | The risk or severity of liver damage can be increased when Tetracosactide is combined with Thiamylal. |
| Aminophylline | The therapeutic efficacy of Thiamylal can be decreased when used in combination with Aminophylline. |
| Meperidine | Thiamylal may increase the hypotensive and central nervous system depressant (CNS depressant) activities of Meperidine. |
| Somatostatin | The risk or severity of adverse effects can be increased when Somatostatin is combined with Thiamylal. |
| Ethanol | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Thiamylal may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Thiamylal. |
| Fluvoxamine | The risk or severity of adverse effects can be increased when Thiamylal is combined with Fluvoxamine. |
| Citalopram | The risk or severity of adverse effects can be increased when Thiamylal is combined with Citalopram. |
| Duloxetine | The risk or severity of adverse effects can be increased when Thiamylal is combined with Duloxetine. |
| Trazodone | The risk or severity of adverse effects can be increased when Thiamylal is combined with Trazodone. |
| Paroxetine | The risk or severity of adverse effects can be increased when Thiamylal is combined with Paroxetine. |
| Sertraline | The risk or severity of adverse effects can be increased when Thiamylal is combined with Sertraline. |
| Sibutramine | The risk or severity of adverse effects can be increased when Thiamylal is combined with Sibutramine. |
| Escitalopram | The risk or severity of adverse effects can be increased when Thiamylal is combined with Escitalopram. |
| Zimelidine | The risk or severity of adverse effects can be increased when Thiamylal is combined with Zimelidine. |
| Dapoxetine | The risk or severity of adverse effects can be increased when Thiamylal is combined with Dapoxetine. |
| Desvenlafaxine | The risk or severity of adverse effects can be increased when Thiamylal is combined with Desvenlafaxine. |
| Seproxetine | The risk or severity of adverse effects can be increased when Thiamylal is combined with Seproxetine. |
| Indalpine | The risk or severity of adverse effects can be increased when Thiamylal is combined with Indalpine. |
| Ritanserin | The risk or severity of adverse effects can be increased when Thiamylal is combined with Ritanserin. |
| Alaproclate | The risk or severity of adverse effects can be increased when Thiamylal is combined with Alaproclate. |
| Milnacipran | The risk or severity of adverse effects can be increased when Thiamylal is combined with Milnacipran. |
| Cyclosporine | The metabolism of Cyclosporine can be increased when combined with Thiamylal. |
| Methyclothiazide | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Methyclothiazide. |
| Chlorthalidone | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Chlorthalidone. |
| Bendroflumethiazide | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Bendroflumethiazide. |
| Metolazone | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Metolazone. |
| Benzthiazide | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Benzthiazide. |
| Hydroflumethiazide | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Hydroflumethiazide. |
| Indapamide | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Indapamide. |
| Chlorothiazide | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Chlorothiazide. |
| Hydrochlorothiazide | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Hydrochlorothiazide. |
| Trichlormethiazide | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Trichlormethiazide. |
| Polythiazide | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Polythiazide. |
| Quinethazone | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Quinethazone. |
| Cyclopenthiazide | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Cyclopenthiazide. |
| Epitizide | The risk or severity of hypotension and orthostatic hypotension can be increased when Thiamylal is combined with Epitizide. |
| Protriptyline | The metabolism of Protriptyline can be increased when combined with Thiamylal. |
| Amoxapine | The metabolism of Amoxapine can be increased when combined with Thiamylal. |
| Desipramine | The metabolism of Desipramine can be increased when combined with Thiamylal. |
| Amineptine | The metabolism of Amineptine can be increased when combined with Thiamylal. |
| Dimetacrine | The metabolism of Dimetacrine can be increased when combined with Thiamylal. |
| Butriptyline | The metabolism of Butriptyline can be increased when combined with Thiamylal. |
| Dosulepin | The metabolism of Dosulepin can be increased when combined with Thiamylal. |
| Oxaprotiline | The metabolism of Oxaprotiline can be increased when combined with Thiamylal. |
| Opipramol | The metabolism of Opipramol can be increased when combined with Thiamylal. |
| Amitriptylinoxide | The metabolism of Amitriptylinoxide can be increased when combined with Thiamylal. |
| Dibenzepin | The metabolism of Dibenzepin can be increased when combined with Thiamylal. |
| Quinupramine | The metabolism of Quinupramine can be increased when combined with Thiamylal. |
| Melitracen | The metabolism of Melitracen can be increased when combined with Thiamylal. |
| Lofepramine | The metabolism of Lofepramine can be increased when combined with Thiamylal. |
| Iprindole | The metabolism of Iprindole can be increased when combined with Thiamylal. |
| Imipramine oxide | The metabolism of Imipramine oxide can be increased when combined with Thiamylal. |
| Phenindione | The metabolism of Phenindione can be increased when combined with Thiamylal. |
| Coumarin | The metabolism of Coumarin can be increased when combined with Thiamylal. |
| Tioclomarol | The metabolism of Tioclomarol can be increased when combined with Thiamylal. |
| (R)-warfarin | The metabolism of (R)-warfarin can be increased when combined with Thiamylal. |
| (S)-Warfarin | The metabolism of (S)-Warfarin can be increased when combined with Thiamylal. |