Candicidin

DB01152

small molecule approved withdrawn

Deskripsi

Candicidin is an antibiotic obtained from a streptomyces (Streptomyces griseus) and active against some fungi of the genus Candida (C. albicans). Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis.

Struktur Molekul 2D

Berat 1109.317
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

315 Data
Eliglustat The metabolism of Eliglustat can be decreased when combined with Candicidin.
Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Candicidin.
Alfentanil The serum concentration of Alfentanil can be increased when it is combined with Candicidin.
Buspirone The metabolism of Buspirone can be decreased when combined with Candicidin.
Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Candicidin.
Cisapride The serum concentration of Cisapride can be increased when it is combined with Candicidin.
Disopyramide Candicidin may increase the QTc-prolonging activities of Disopyramide.
Estazolam The serum concentration of Estazolam can be increased when it is combined with Candicidin.
Quinine The serum concentration of Quinine can be increased when it is combined with Candicidin.
Quinidine The serum concentration of Quinidine can be increased when it is combined with Candicidin.
Repaglinide The serum concentration of Repaglinide can be increased when it is combined with Candicidin.
Sirolimus The metabolism of Sirolimus can be decreased when combined with Candicidin.
Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Candicidin.
Terfenadine The serum concentration of Terfenadine can be increased when it is combined with Candicidin.
Triazolam The serum concentration of Triazolam can be increased when it is combined with Candicidin.
Cilostazol The metabolism of Cilostazol can be decreased when combined with Candicidin.
Colchicine The metabolism of Colchicine can be decreased when combined with Candicidin.
Iloperidone The metabolism of Iloperidone can be decreased when combined with Candicidin.
Retapamulin The metabolism of Retapamulin can be decreased when combined with Candicidin.
Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Candicidin.
Vardenafil The metabolism of Vardenafil can be decreased when combined with Candicidin.
Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Candicidin.
Zopiclone The metabolism of Zopiclone can be decreased when combined with Candicidin.
Lovastatin The metabolism of Lovastatin can be decreased when combined with Candicidin.
Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Candicidin.
Alprazolam The serum concentration of Alprazolam can be increased when it is combined with Candicidin.
Warfarin The serum concentration of Warfarin can be increased when it is combined with Candicidin.
Acenocoumarol The serum concentration of Acenocoumarol can be increased when it is combined with Candicidin.
(R)-warfarin The serum concentration of (R)-warfarin can be increased when it is combined with Candicidin.
R,S-Warfarin alcohol The serum concentration of R,S-Warfarin alcohol can be increased when it is combined with Candicidin.
S,R-Warfarin alcohol The serum concentration of S,R-Warfarin alcohol can be increased when it is combined with Candicidin.
(S)-Warfarin The serum concentration of (S)-Warfarin can be increased when it is combined with Candicidin.
Midazolam The serum concentration of Midazolam can be increased when it is combined with Candicidin.
Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Candicidin.
Telaprevir The serum concentration of Telaprevir can be increased when it is combined with Candicidin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Candicidin.
Vintafolide The serum concentration of Vintafolide can be increased when it is combined with Candicidin.
Vincamine The serum concentration of Vincamine can be increased when it is combined with Candicidin.
Acetyldigitoxin The serum concentration of Acetyldigitoxin can be increased when it is combined with Candicidin.
Deslanoside The serum concentration of Deslanoside can be increased when it is combined with Candicidin.
Ouabain The serum concentration of Ouabain can be increased when it is combined with Candicidin.
Oleandrin The serum concentration of Oleandrin can be increased when it is combined with Candicidin.
Cymarin The serum concentration of Cymarin can be increased when it is combined with Candicidin.
Proscillaridin The serum concentration of Proscillaridin can be increased when it is combined with Candicidin.
Metildigoxin The serum concentration of Metildigoxin can be increased when it is combined with Candicidin.
Lanatoside C The serum concentration of Lanatoside C can be increased when it is combined with Candicidin.
Gitoformate The serum concentration of Gitoformate can be increased when it is combined with Candicidin.
Acetyldigoxin The serum concentration of Acetyldigoxin can be increased when it is combined with Candicidin.
Peruvoside The serum concentration of Peruvoside can be increased when it is combined with Candicidin.
Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Candicidin.
Oxtriphylline The metabolism of Oxtriphylline can be decreased when combined with Candicidin.
Doxofylline The metabolism of Doxofylline can be decreased when combined with Candicidin.
Bamifylline The metabolism of Bamifylline can be decreased when combined with Candicidin.
Acefylline The metabolism of Acefylline can be decreased when combined with Candicidin.
Bufylline The metabolism of Bufylline can be decreased when combined with Candicidin.
Fenethylline The metabolism of Fenethylline can be decreased when combined with Candicidin.
Proxyphylline The metabolism of Proxyphylline can be decreased when combined with Candicidin.
Bromotheophylline The metabolism of Bromotheophylline can be decreased when combined with Candicidin.
Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Candicidin.
8-azaguanine The metabolism of 8-azaguanine can be decreased when combined with Candicidin.
7,9-Dimethylguanine The metabolism of 7,9-Dimethylguanine can be decreased when combined with Candicidin.
Xanthine The metabolism of Xanthine can be decreased when combined with Candicidin.
7-Deazaguanine The metabolism of 7-Deazaguanine can be decreased when combined with Candicidin.
Guanine The metabolism of Guanine can be decreased when combined with Candicidin.
9-Methylguanine The metabolism of 9-Methylguanine can be decreased when combined with Candicidin.
Peldesine The metabolism of Peldesine can be decreased when combined with Candicidin.
Hypoxanthine The metabolism of Hypoxanthine can be decreased when combined with Candicidin.
9-Deazaguanine The metabolism of 9-Deazaguanine can be decreased when combined with Candicidin.
Valomaciclovir The metabolism of Valomaciclovir can be decreased when combined with Candicidin.
3-isobutyl-1-methyl-7H-xanthine The metabolism of 3-isobutyl-1-methyl-7H-xanthine can be decreased when combined with Candicidin.
Uric acid The metabolism of Uric acid can be decreased when combined with Candicidin.
6-O-benzylguanine The metabolism of 6-O-benzylguanine can be decreased when combined with Candicidin.
Lisofylline The metabolism of Lisofylline can be decreased when combined with Candicidin.
Lobucavir The metabolism of Lobucavir can be decreased when combined with Candicidin.
Cafedrine The metabolism of Cafedrine can be decreased when combined with Candicidin.
Theodrenaline The metabolism of Theodrenaline can be decreased when combined with Candicidin.
Etamiphylline The metabolism of Etamiphylline can be decreased when combined with Candicidin.
Pentifylline The metabolism of Pentifylline can be decreased when combined with Candicidin.
Furafylline The metabolism of Furafylline can be decreased when combined with Candicidin.
Theobromine The metabolism of Theobromine can be decreased when combined with Candicidin.
Propentofylline The metabolism of Propentofylline can be decreased when combined with Candicidin.
Caffeine The metabolism of Caffeine can be decreased when combined with Candicidin.
8-chlorotheophylline The metabolism of 8-chlorotheophylline can be decreased when combined with Candicidin.
Mercaptopurine The metabolism of Mercaptopurine can be decreased when combined with Candicidin.
PCS-499 The metabolism of PCS-499 can be decreased when combined with Candicidin.
Methylergometrine The serum concentration of Methylergometrine can be increased when it is combined with Candicidin.
Lisuride The serum concentration of Lisuride can be increased when it is combined with Candicidin.
Nicergoline The serum concentration of Nicergoline can be increased when it is combined with Candicidin.
Ergoloid mesylate The serum concentration of Ergoloid mesylate can be increased when it is combined with Candicidin.
Pergolide The serum concentration of Pergolide can be increased when it is combined with Candicidin.
Ergometrine The serum concentration of Ergometrine can be increased when it is combined with Candicidin.
Lysergic acid diethylamide The serum concentration of Lysergic acid diethylamide can be increased when it is combined with Candicidin.
Dihydroergocornine The serum concentration of Dihydroergocornine can be increased when it is combined with Candicidin.
Dihydroergocristine The serum concentration of Dihydroergocristine can be increased when it is combined with Candicidin.
Dihydroergocryptine The serum concentration of Dihydroergocryptine can be increased when it is combined with Candicidin.
Terguride The serum concentration of Terguride can be increased when it is combined with Candicidin.
Metergoline The serum concentration of Metergoline can be increased when it is combined with Candicidin.
Methysergide The serum concentration of Methysergide can be increased when it is combined with Candicidin.
Bromocriptine The serum concentration of Bromocriptine can be increased when it is combined with Candicidin.
BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Candicidin.

Target Protein

Ergosterol

Referensi & Sumber

Synthesis reference: Siminoff, P.; U.S. Patent 2,872,373; February 3,1959; assigned to S.B. Penick & Company, Inc. Waksman, S.A. and Lechevalier, H.A.; U.S. Patent 2,992,162; July 11,1961; assigned to Rutgers Research and Educational Foundation.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Vanobid

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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