Peringatan Keamanan

Nausea, vomiting, diarrhoea, allergic rashes may occur

Cefadroxil

DB01140

small molecule approved vet_approved withdrawn

Deskripsi

Long-acting, broad-spectrum, water-soluble, cephalexin derivative.

Struktur Molekul 2D

Berat 363.388
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 1.5 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Cefadroxil is well absorbed on oral administration; food does not interfere with its absorption.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Over 90% of the drug is excreted unchanged in the urine within 24 hours. Cefadroxil was detected in the placenta and breast milk.

Interaksi Makanan

1 Data
  • 1. Take with or without food. Administration with food may be helpful in diminishing potential gastrointestinal complaints occasionally associated with oral cephalosporin therapy.

Interaksi Obat

886 Data
Probenecid The serum concentration of Cefadroxil can be increased when it is combined with Probenecid.
Foscarnet The risk or severity of nephrotoxicity can be increased when Cefadroxil is combined with Foscarnet.
Mannitol The risk or severity of nephrotoxicity can be increased when Mannitol is combined with Cefadroxil.
Tenofovir disoproxil Cefadroxil may increase the nephrotoxic activities of Tenofovir disoproxil.
Tenofovir alafenamide The serum concentration of Tenofovir alafenamide can be increased when it is combined with Cefadroxil.
Tenofovir Cefadroxil may increase the nephrotoxic activities of Tenofovir.
Succinic acid The excretion of Succinic acid can be decreased when combined with Cefadroxil.
Citrulline The excretion of Citrulline can be decreased when combined with Cefadroxil.
Pravastatin The excretion of Pravastatin can be decreased when combined with Cefadroxil.
Aminohippuric acid The excretion of Aminohippuric acid can be decreased when combined with Cefadroxil.
Zidovudine The excretion of Zidovudine can be decreased when combined with Cefadroxil.
Cefdinir The excretion of Cefdinir can be decreased when combined with Cefadroxil.
Leucovorin The excretion of Leucovorin can be decreased when combined with Cefadroxil.
Fluorescein The excretion of Fluorescein can be decreased when combined with Cefadroxil.
Hydrocortisone The excretion of Hydrocortisone can be decreased when combined with Cefadroxil.
Quinapril The excretion of Quinapril can be decreased when combined with Cefadroxil.
Dinoprostone The excretion of Dinoprostone can be decreased when combined with Cefadroxil.
Famotidine The excretion of Famotidine can be decreased when combined with Cefadroxil.
Fexofenadine The excretion of Fexofenadine can be decreased when combined with Cefadroxil.
Benzylpenicillin The excretion of Benzylpenicillin can be decreased when combined with Cefadroxil.
Rosuvastatin The excretion of Rosuvastatin can be decreased when combined with Cefadroxil.
Captopril The excretion of Captopril can be decreased when combined with Cefadroxil.
Tazobactam The excretion of Tazobactam can be decreased when combined with Cefadroxil.
Cyclic adenosine monophosphate The excretion of Cyclic adenosine monophosphate can be decreased when combined with Cefadroxil.
Cholic Acid The excretion of Cholic Acid can be decreased when combined with Cefadroxil.
Glutaric Acid The excretion of Glutaric Acid can be decreased when combined with Cefadroxil.
Oxalic Acid The excretion of Oxalic Acid can be decreased when combined with Cefadroxil.
Taurocholic acid The excretion of Taurocholic acid can be decreased when combined with Cefadroxil.
Ellagic acid The excretion of Ellagic acid can be decreased when combined with Cefadroxil.
Avibactam The excretion of Avibactam can be decreased when combined with Cefadroxil.
Eluxadoline The excretion of Eluxadoline can be decreased when combined with Cefadroxil.
Silibinin The excretion of Silibinin can be decreased when combined with Cefadroxil.
Relebactam The excretion of Relebactam can be decreased when combined with Cefadroxil.
Cefotiam The excretion of Cefotiam can be decreased when combined with Cefadroxil.
Indomethacin The excretion of Indomethacin can be decreased when combined with Cefadroxil.
Methotrexate The excretion of Methotrexate can be decreased when combined with Cefadroxil.
Cephalexin The excretion of Cephalexin can be decreased when combined with Cefadroxil.
Valaciclovir The excretion of Valaciclovir can be decreased when combined with Cefadroxil.
Acyclovir The excretion of Acyclovir can be decreased when combined with Cefadroxil.
Cefaclor The excretion of Cefaclor can be decreased when combined with Cefadroxil.
Bumetanide The excretion of Bumetanide can be decreased when combined with Cefadroxil.
Oseltamivir The excretion of Oseltamivir can be decreased when combined with Cefadroxil.
Conjugated estrogens The excretion of Conjugated estrogens can be decreased when combined with Cefadroxil.
Piperacillin The excretion of Piperacillin can be decreased when combined with Cefadroxil.
Trifluridine The excretion of Trifluridine can be decreased when combined with Cefadroxil.
Allopurinol The excretion of Allopurinol can be decreased when combined with Cefadroxil.
Cimetidine The excretion of Cimetidine can be decreased when combined with Cefadroxil.
Levocarnitine The excretion of Levocarnitine can be decreased when combined with Cefadroxil.
Tetracycline The excretion of Tetracycline can be decreased when combined with Cefadroxil.
Estradiol The excretion of Estradiol can be decreased when combined with Cefadroxil.
Ranitidine The excretion of Ranitidine can be decreased when combined with Cefadroxil.
Sitagliptin The excretion of Sitagliptin can be decreased when combined with Cefadroxil.
Ceftibuten The excretion of Ceftibuten can be decreased when combined with Cefadroxil.
Doripenem The excretion of Doripenem can be decreased when combined with Cefadroxil.
Saxagliptin The excretion of Saxagliptin can be decreased when combined with Cefadroxil.
Baricitinib The serum concentration of Baricitinib can be increased when it is combined with Cefadroxil.
Cefazolin The excretion of Cefazolin can be decreased when combined with Cefadroxil.
Ceftizoxime The excretion of Ceftizoxime can be decreased when combined with Cefadroxil.
Cefacetrile The excretion of Cefacetrile can be decreased when combined with Cefadroxil.
Cefaloridine The excretion of Cefaloridine can be decreased when combined with Cefadroxil.
Dexamethasone The excretion of Dexamethasone can be decreased when combined with Cefadroxil.
Oxytetracycline The excretion of Oxytetracycline can be decreased when combined with Cefadroxil.
Prednisolone phosphate The excretion of Prednisolone phosphate can be decreased when combined with Cefadroxil.
Dexamethasone acetate The excretion of Dexamethasone acetate can be decreased when combined with Cefadroxil.
Acamprosate The excretion of Acamprosate can be decreased when combined with Cefadroxil.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Cefadroxil.
Triamterene The risk or severity of nephrotoxicity can be increased when Triamterene is combined with Cefadroxil.
Etacrynic acid The risk or severity of nephrotoxicity can be increased when Etacrynic acid is combined with Cefadroxil.
Hydrochlorothiazide The excretion of Hydrochlorothiazide can be decreased when combined with Cefadroxil.
Cyclosporine The risk or severity of nephrotoxicity can be increased when Cyclosporine is combined with Cefadroxil.
Icosapent The risk or severity of nephrotoxicity can be increased when Icosapent is combined with Cefadroxil.
Mesalazine The risk or severity of nephrotoxicity can be increased when Mesalazine is combined with Cefadroxil.
Cefmenoxime The risk or severity of nephrotoxicity can be increased when Cefmenoxime is combined with Cefadroxil.
Cefmetazole The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cefadroxil.
Cidofovir The risk or severity of nephrotoxicity can be increased when Cidofovir is combined with Cefadroxil.
Cefpiramide The risk or severity of nephrotoxicity can be increased when Cefpiramide is combined with Cefadroxil.
Ceftazidime The risk or severity of nephrotoxicity can be increased when Ceftazidime is combined with Cefadroxil.
Loracarbef The risk or severity of nephrotoxicity can be increased when Loracarbef is combined with Cefadroxil.
Cefalotin The risk or severity of nephrotoxicity can be increased when Cefalotin is combined with Cefadroxil.
Nabumetone The risk or severity of nephrotoxicity can be increased when Nabumetone is combined with Cefadroxil.
Ketorolac The risk or severity of nephrotoxicity can be increased when Ketorolac is combined with Cefadroxil.
Tenoxicam The risk or severity of nephrotoxicity can be increased when Tenoxicam is combined with Cefadroxil.
Celecoxib The risk or severity of nephrotoxicity can be increased when Celecoxib is combined with Cefadroxil.
Cefotaxime The risk or severity of nephrotoxicity can be increased when Cefotaxime is combined with Cefadroxil.
Tolmetin The risk or severity of nephrotoxicity can be increased when Tolmetin is combined with Cefadroxil.
Rofecoxib The risk or severity of nephrotoxicity can be increased when Rofecoxib is combined with Cefadroxil.
Piroxicam The risk or severity of nephrotoxicity can be increased when Piroxicam is combined with Cefadroxil.
Fenoprofen The risk or severity of nephrotoxicity can be increased when Fenoprofen is combined with Cefadroxil.
Valdecoxib The risk or severity of nephrotoxicity can be increased when Valdecoxib is combined with Cefadroxil.
Diclofenac The risk or severity of nephrotoxicity can be increased when Diclofenac is combined with Cefadroxil.
Sulindac The risk or severity of nephrotoxicity can be increased when Sulindac is combined with Cefadroxil.
Bacitracin The risk or severity of nephrotoxicity can be increased when Bacitracin is combined with Cefadroxil.
Amphotericin B The risk or severity of nephrotoxicity can be increased when Amphotericin B is combined with Cefadroxil.
Cephaloglycin The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefadroxil.
Flurbiprofen The risk or severity of nephrotoxicity can be increased when Flurbiprofen is combined with Cefadroxil.
Adefovir dipivoxil The risk or severity of nephrotoxicity can be increased when Adefovir dipivoxil is combined with Cefadroxil.
Pentamidine The risk or severity of nephrotoxicity can be increased when Pentamidine is combined with Cefadroxil.
Etodolac The risk or severity of nephrotoxicity can be increased when Etodolac is combined with Cefadroxil.
Mefenamic acid The risk or severity of nephrotoxicity can be increased when Mefenamic acid is combined with Cefadroxil.
Naproxen The risk or severity of nephrotoxicity can be increased when Naproxen is combined with Cefadroxil.

Target Protein

Penicillin-binding protein 3 pbp3
Penicillin-binding protein 1A pbpA
Penicillin-binding protein 1b pbp1b
Penicillin-binding protein 2B penA

Referensi & Sumber

Synthesis reference: Leonardo Marsili, "Substantially anhydrous crystalline cefadroxil and method for producing it." U.S. Patent US5329001, issued April, 1978.

Contoh Produk & Brand

Produk: 111 • International brands: 5
Produk
  • Apo-cefadroxil
    Capsule • 500 mg • Oral • Canada • Generic • Approved
  • Cefadroxil
    Tablet, film coated • 1 g/1 • Oral • US • Approved
  • Cefadroxil
    Capsule • 500 mg/1 • Oral • US • Generic • Approved
  • Cefadroxil
    Capsule • 500 mg/1 • Oral • US • Generic • Approved
  • Cefadroxil
    Powder, for suspension • 250 mg/5mL • Oral • US • Generic • Approved
  • Cefadroxil
    Powder, for suspension • 500 mg/5mL • Oral • US • Generic • Approved
  • Cefadroxil
    Capsule • 500 mg/1 • Oral • US • Generic • Approved
  • Cefadroxil
    Capsule • 500 mg/1 • Oral • US • Generic • Approved
Menampilkan 8 dari 111 produk.
International Brands
  • Baxan — Bristol-Myers Squibb
  • Bidocef — Bristol-Myers Squibb
  • Cefamox — Bristol-Myers Squibb
  • Duracef — Bristol-Myers Squibb
  • Oracefal — Bristol-Myers Squibb

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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