Oral, mouse: LD50 = 987 mg/kg; Oral, rabbit: LD50 = 2500 mg/kg; Oral, rat: LD50 = 1600 mg/kg
Phenacemide is used to control certain seizures in the treatment of epilepsy. This medicine acts on the central nervous system (CNS) to reduce the number and severity of seizures.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Buprenorphine | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Phenacemide. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Phenacemide. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Phenacemide. |
| Hydrocodone | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Phenacemide. |
| Magnesium sulfate | The therapeutic efficacy of Phenacemide can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Metyrosine | Phenacemide may increase the sedative activities of Metyrosine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Phenacemide. |
| Mirtazapine | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Phenacemide. |
| Orphenadrine | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Phenacemide. |
| Pramipexole | Phenacemide may increase the sedative activities of Pramipexole. |
| Ropinirole | Phenacemide may increase the sedative activities of Ropinirole. |
| Rotigotine | Phenacemide may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Phenacemide. |
| Sodium oxybate | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Suvorexant | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Phenacemide. |
| Thalidomide | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Mefloquine | The therapeutic efficacy of Phenacemide can be decreased when used in combination with Mefloquine. |
| Mianserin | The therapeutic efficacy of Phenacemide can be decreased when used in combination with Mianserin. |
| Orlistat | Orlistat can cause a decrease in the absorption of Phenacemide resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Topotecan | Phenacemide may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Phenacemide. |
| Tetracosactide | The risk or severity of liver damage can be increased when Tetracosactide is combined with Phenacemide. |
| Ethanol | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Phenacemide may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Phenacemide. |
| Fluvoxamine | The risk or severity of adverse effects can be increased when Phenacemide is combined with Fluvoxamine. |
| Citalopram | The risk or severity of adverse effects can be increased when Phenacemide is combined with Citalopram. |
| Duloxetine | The risk or severity of adverse effects can be increased when Phenacemide is combined with Duloxetine. |
| Trazodone | The risk or severity of adverse effects can be increased when Phenacemide is combined with Trazodone. |
| Paroxetine | The risk or severity of adverse effects can be increased when Phenacemide is combined with Paroxetine. |
| Sertraline | The risk or severity of adverse effects can be increased when Phenacemide is combined with Sertraline. |
| Sibutramine | The risk or severity of adverse effects can be increased when Phenacemide is combined with Sibutramine. |
| Nefazodone | The risk or severity of adverse effects can be increased when Phenacemide is combined with Nefazodone. |
| Escitalopram | The risk or severity of adverse effects can be increased when Phenacemide is combined with Escitalopram. |
| Zimelidine | The risk or severity of adverse effects can be increased when Phenacemide is combined with Zimelidine. |
| Dapoxetine | The risk or severity of adverse effects can be increased when Phenacemide is combined with Dapoxetine. |
| Milnacipran | The risk or severity of adverse effects can be increased when Phenacemide is combined with Milnacipran. |
| Desvenlafaxine | The risk or severity of adverse effects can be increased when Phenacemide is combined with Desvenlafaxine. |
| Seproxetine | The risk or severity of adverse effects can be increased when Phenacemide is combined with Seproxetine. |
| Indalpine | The risk or severity of adverse effects can be increased when Phenacemide is combined with Indalpine. |
| Ritanserin | The risk or severity of adverse effects can be increased when Phenacemide is combined with Ritanserin. |
| Alaproclate | The risk or severity of adverse effects can be increased when Phenacemide is combined with Alaproclate. |
| Amitriptyline | The risk or severity of CNS depression can be increased when Amitriptyline is combined with Phenacemide. |
| Cyproheptadine | The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Phenacemide. |
| Imipramine | The risk or severity of CNS depression can be increased when Imipramine is combined with Phenacemide. |
| Nortriptyline | The risk or severity of CNS depression can be increased when Nortriptyline is combined with Phenacemide. |
| Amoxapine | The risk or severity of CNS depression can be increased when Amoxapine is combined with Phenacemide. |
| Propiomazine | The risk or severity of CNS depression can be increased when Propiomazine is combined with Phenacemide. |
| Cocaine | The risk or severity of methemoglobinemia can be increased when Phenacemide is combined with Cocaine. |
| Quinidine | The therapeutic efficacy of Phenacemide can be decreased when used in combination with Quinidine. |
| Maprotiline | The risk or severity of CNS depression can be increased when Maprotiline is combined with Phenacemide. |
| Doxepin | The risk or severity of CNS depression can be increased when Phenacemide is combined with Doxepin. |
| Desipramine | The risk or severity of CNS depression can be increased when Phenacemide is combined with Desipramine. |
| Pizotifen | The risk or severity of CNS depression can be increased when Phenacemide is combined with Pizotifen. |
| Dosulepin | The risk or severity of CNS depression can be increased when Phenacemide is combined with Dosulepin. |
| Zopiclone | The risk or severity of adverse effects can be increased when Phenacemide is combined with Zopiclone. |
| Botulinum toxin type B | The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Phenacemide. |
| Botulinum toxin type A | The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Phenacemide. |
| Tryptophan | The risk or severity of CNS depression can be increased when Tryptophan is combined with Phenacemide. |
| Baclofen | Baclofen may increase the central nervous system depressant (CNS depressant) activities of Phenacemide. |
| Lorazepam | The risk or severity of CNS depression can be increased when Lorazepam is combined with Phenacemide. |
| Ethchlorvynol | The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Phenacemide. |
| Succinylcholine | The risk or severity of CNS depression can be increased when Succinylcholine is combined with Phenacemide. |
| Reserpine | The risk or severity of CNS depression can be increased when Reserpine is combined with Phenacemide. |
| Eletriptan | The risk or severity of CNS depression can be increased when Eletriptan is combined with Phenacemide. |
| Enflurane | The risk or severity of CNS depression can be increased when Enflurane is combined with Phenacemide. |
| Temazepam | The risk or severity of CNS depression can be increased when Temazepam is combined with Phenacemide. |
| Reboxetine | The risk or severity of CNS depression can be increased when Reboxetine is combined with Phenacemide. |
| Butabarbital | The risk or severity of CNS depression can be increased when Butabarbital is combined with Phenacemide. |
| Butalbital | The risk or severity of CNS depression can be increased when Butalbital is combined with Phenacemide. |
| Methysergide | The risk or severity of CNS depression can be increased when Methysergide is combined with Phenacemide. |
| Cabergoline | The risk or severity of CNS depression can be increased when Cabergoline is combined with Phenacemide. |
| Phenytoin | The risk or severity of CNS depression can be increased when Phenytoin is combined with Phenacemide. |
| Topiramate | The risk or severity of CNS depression can be increased when Topiramate is combined with Phenacemide. |
| Clemastine | The risk or severity of CNS depression can be increased when Clemastine is combined with Phenacemide. |
| Venlafaxine | The risk or severity of CNS depression can be increased when Venlafaxine is combined with Phenacemide. |
| Etomidate | The risk or severity of CNS depression can be increased when Etomidate is combined with Phenacemide. |
| Morphine | The risk or severity of CNS depression can be increased when Morphine is combined with Phenacemide. |
| Talbutal | The risk or severity of CNS depression can be increased when Talbutal is combined with Phenacemide. |
| Pentobarbital | The risk or severity of CNS depression can be increased when Pentobarbital is combined with Phenacemide. |
| Valproic acid | The risk or severity of CNS depression can be increased when Valproic acid is combined with Phenacemide. |
| Zolmitriptan | The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Phenacemide. |
| Codeine | The risk or severity of CNS depression can be increased when Codeine is combined with Phenacemide. |
| Dihydroergotamine | The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Phenacemide. |
| Tolcapone | The risk or severity of CNS depression can be increased when Tolcapone is combined with Phenacemide. |
| Hydromorphone | The risk or severity of CNS depression can be increased when Hydromorphone is combined with Phenacemide. |
| Olanzapine | The risk or severity of CNS depression can be increased when Olanzapine is combined with Phenacemide. |
| Cetirizine | The risk or severity of CNS depression can be increased when Cetirizine is combined with Phenacemide. |
| Protriptyline | The risk or severity of CNS depression can be increased when Protriptyline is combined with Phenacemide. |
| Trimethadione | The risk or severity of CNS depression can be increased when Trimethadione is combined with Phenacemide. |
| Clobazam | The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Phenacemide. |
| Chlorzoxazone | The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Phenacemide. |