Arbutamine

DB01102

small molecule approved

Deskripsi

Arbutamine, administered through a closed-loop, computer-controlled drug-delivery system, is indicated to elicit acute cardiovascular responses, similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease in patients who cannot exercise adequately .

Struktur Molekul 2D

Berat 317.3795
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) Elimination half-life is approximately 8 minutes.
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Primarily metabolized to methoxyarbutamine. Another possible metabolite is ketoarbutamine. The metabolites of arbutamine appear to have less pharmacological activity and a longer half-life and than the parental drug.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

786 Data
Valsartan Arbutamine may decrease the antihypertensive activities of Valsartan.
Ramipril Arbutamine may decrease the antihypertensive activities of Ramipril.
Reserpine Arbutamine may decrease the antihypertensive activities of Reserpine.
Remikiren Arbutamine may decrease the antihypertensive activities of Remikiren.
Isradipine Arbutamine may decrease the antihypertensive activities of Isradipine.
Olmesartan Arbutamine may decrease the antihypertensive activities of Olmesartan.
Nitroprusside Arbutamine may decrease the antihypertensive activities of Nitroprusside.
Diltiazem Arbutamine may decrease the antihypertensive activities of Diltiazem.
Minoxidil Arbutamine may decrease the antihypertensive activities of Minoxidil.
Treprostinil Arbutamine may decrease the antihypertensive activities of Treprostinil.
Amlodipine Arbutamine may decrease the antihypertensive activities of Amlodipine.
Nimodipine Arbutamine may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Arbutamine may decrease the antihypertensive activities of Nisoldipine.
Fosinopril Arbutamine may decrease the antihypertensive activities of Fosinopril.
Trandolapril Arbutamine may decrease the antihypertensive activities of Trandolapril.
Lercanidipine Arbutamine may decrease the antihypertensive activities of Lercanidipine.
Benazepril Arbutamine may decrease the antihypertensive activities of Benazepril.
Bosentan Arbutamine may decrease the antihypertensive activities of Bosentan.
Enalapril Arbutamine may decrease the antihypertensive activities of Enalapril.
Candoxatril Arbutamine may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Arbutamine may decrease the antihypertensive activities of Mecamylamine.
Losartan Arbutamine may decrease the antihypertensive activities of Losartan.
Moexipril Arbutamine may decrease the antihypertensive activities of Moexipril.
Eplerenone Arbutamine may decrease the antihypertensive activities of Eplerenone.
Lisinopril Arbutamine may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Arbutamine may decrease the antihypertensive activities of Nitroglycerin.
Metyrosine Arbutamine may decrease the antihypertensive activities of Metyrosine.
Cryptenamine Arbutamine may decrease the antihypertensive activities of Cryptenamine.
Perindopril Arbutamine may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Arbutamine may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Arbutamine may decrease the antihypertensive activities of Fenoldopam.
Tadalafil Arbutamine may decrease the antihypertensive activities of Tadalafil.
Eprosartan Arbutamine may decrease the antihypertensive activities of Eprosartan.
Quinapril Arbutamine may decrease the antihypertensive activities of Quinapril.
Telmisartan Arbutamine may decrease the antihypertensive activities of Telmisartan.
Methyldopa Arbutamine may decrease the antihypertensive activities of Methyldopa.
Irbesartan Arbutamine may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Arbutamine may decrease the antihypertensive activities of Nitrendipine.
Deserpidine Arbutamine may decrease the antihypertensive activities of Deserpidine.
Pentolinium Arbutamine may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Arbutamine may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Arbutamine may decrease the antihypertensive activities of Diazoxide.
Captopril Arbutamine may decrease the antihypertensive activities of Captopril.
Epoprostenol Arbutamine may decrease the antihypertensive activities of Epoprostenol.
Bepridil Arbutamine may decrease the antihypertensive activities of Bepridil.
Hydralazine Arbutamine may decrease the antihypertensive activities of Hydralazine.
Cilazapril Arbutamine may decrease the antihypertensive activities of Cilazapril.
Saprisartan Arbutamine may decrease the antihypertensive activities of Saprisartan.
Spirapril Arbutamine may decrease the antihypertensive activities of Spirapril.
Mibefradil Arbutamine may decrease the antihypertensive activities of Mibefradil.
Tienilic acid Arbutamine may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Arbutamine may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Arbutamine may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Arbutamine may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Arbutamine may decrease the antihypertensive activities of Diethylnorspermine.
Nilvadipine Arbutamine may decrease the antihypertensive activities of Nilvadipine.
Pinacidil Arbutamine may decrease the antihypertensive activities of Pinacidil.
Temocapril Arbutamine may decrease the antihypertensive activities of Temocapril.
Riociguat Arbutamine may decrease the antihypertensive activities of Riociguat.
Macitentan Arbutamine may decrease the antihypertensive activities of Macitentan.
Hexamethonium Arbutamine may decrease the antihypertensive activities of Hexamethonium.
Aliskiren Arbutamine may decrease the antihypertensive activities of Aliskiren.
Nicorandil Arbutamine may decrease the antihypertensive activities of Nicorandil.
Efonidipine Arbutamine may decrease the antihypertensive activities of Efonidipine.
Lacidipine Arbutamine may decrease the antihypertensive activities of Lacidipine.
Manidipine Arbutamine may decrease the antihypertensive activities of Manidipine.
Rauwolfia serpentina root Arbutamine may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Arbutamine may decrease the antihypertensive activities of Enalaprilat.
Selexipag Arbutamine may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Arbutamine may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Arbutamine may decrease the antihypertensive activities of Imidapril.
BQ-123 Arbutamine may decrease the antihypertensive activities of BQ-123.
Tetrahydropalmatine Arbutamine may decrease the antihypertensive activities of Tetrahydropalmatine.
Cicletanine Arbutamine may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Arbutamine may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Arbutamine may decrease the antihypertensive activities of Zofenopril.
Guanoxan Arbutamine may decrease the antihypertensive activities of Guanoxan.
Delapril Arbutamine may decrease the antihypertensive activities of Delapril.
Vincamine Arbutamine may decrease the antihypertensive activities of Vincamine.
Linsidomine Arbutamine may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Arbutamine may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Arbutamine may decrease the antihypertensive activities of Tolonidine.
Endralazine Arbutamine may decrease the antihypertensive activities of Endralazine.
Cadralazine Arbutamine may decrease the antihypertensive activities of Cadralazine.
Bietaserpine Arbutamine may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Arbutamine may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Arbutamine may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Arbutamine may decrease the antihypertensive activities of Guanoclor.
Muzolimine Arbutamine may decrease the antihypertensive activities of Muzolimine.
Xipamide Arbutamine may decrease the antihypertensive activities of Xipamide.
Candesartan Arbutamine may decrease the antihypertensive activities of Candesartan.
Dexniguldipine Arbutamine may decrease the antihypertensive activities of Dexniguldipine.
Tocopherylquinone Arbutamine may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Arbutamine may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Arbutamine may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Arbutamine may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Arbutamine may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Arbutamine may decrease the antihypertensive activities of Quinaprilat.
Felodipine Arbutamine may decrease the antihypertensive activities of Felodipine.
Levamlodipine Arbutamine may decrease the antihypertensive activities of Levamlodipine.

Target Protein

Beta-1 adrenergic receptor ADRB1
Beta-2 adrenergic receptor ADRB2
Beta-3 adrenergic receptor ADRB3

Referensi & Sumber

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