Oxamniquine

DB01096

small molecule approved

Deskripsi

An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. (From Martidale, The Extra Pharmacopoeia, 31st ed, p121)

Struktur Molekul 2D

Berat 279.3348
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 1-2.5 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Well absorbed orally

Metabolisme

Probably hepatic

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

248 Data
Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Oxamniquine.
Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Oxamniquine.
Aripiprazole lauroxil The metabolism of Aripiprazole lauroxil can be decreased when combined with Oxamniquine.
Fluvoxamine The metabolism of Fluvoxamine can be decreased when combined with Oxamniquine.
Amphetamine The metabolism of Amphetamine can be decreased when combined with Oxamniquine.
Cevimeline The metabolism of Cevimeline can be decreased when combined with Oxamniquine.
Esmolol The metabolism of Esmolol can be decreased when combined with Oxamniquine.
Bortezomib The metabolism of Bortezomib can be decreased when combined with Oxamniquine.
Betaxolol The metabolism of Betaxolol can be decreased when combined with Oxamniquine.
Sildenafil The metabolism of Sildenafil can be decreased when combined with Oxamniquine.
Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Oxamniquine.
Citalopram The metabolism of Citalopram can be decreased when combined with Oxamniquine.
Eletriptan The metabolism of Eletriptan can be decreased when combined with Oxamniquine.
Nevirapine The metabolism of Nevirapine can be decreased when combined with Oxamniquine.
Ranolazine The metabolism of Ranolazine can be decreased when combined with Oxamniquine.
Benzatropine The metabolism of Benzatropine can be decreased when combined with Oxamniquine.
Metoprolol The metabolism of Metoprolol can be decreased when combined with Oxamniquine.
Lidocaine The metabolism of Lidocaine can be decreased when combined with Oxamniquine.
Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Oxamniquine.
Bupivacaine The metabolism of Bupivacaine can be decreased when combined with Oxamniquine.
Acetaminophen The metabolism of Acetaminophen can be decreased when combined with Oxamniquine.
Gefitinib The metabolism of Gefitinib can be decreased when combined with Oxamniquine.
Codeine The metabolism of Codeine can be decreased when combined with Oxamniquine.
Methadone The metabolism of Methadone can be decreased when combined with Oxamniquine.
Olanzapine The metabolism of Olanzapine can be decreased when combined with Oxamniquine.
Atenolol The metabolism of Atenolol can be decreased when combined with Oxamniquine.
Terfenadine The metabolism of Terfenadine can be decreased when combined with Oxamniquine.
Diltiazem The metabolism of Diltiazem can be decreased when combined with Oxamniquine.
Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Oxamniquine.
Clozapine The serum concentration of Clozapine can be increased when it is combined with Oxamniquine.
Mirtazapine The metabolism of Mirtazapine can be decreased when combined with Oxamniquine.
Palonosetron The metabolism of Palonosetron can be decreased when combined with Oxamniquine.
Mexiletine The metabolism of Mexiletine can be decreased when combined with Oxamniquine.
Progesterone The metabolism of Progesterone can be decreased when combined with Oxamniquine.
Remoxipride The metabolism of Remoxipride can be decreased when combined with Oxamniquine.
Promazine The metabolism of Promazine can be decreased when combined with Oxamniquine.
Zolpidem The metabolism of Zolpidem can be decreased when combined with Oxamniquine.
Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Oxamniquine.
Quinine The metabolism of Quinine can be decreased when combined with Oxamniquine.
Fluoxetine The metabolism of Fluoxetine can be decreased when combined with Oxamniquine.
Duloxetine The metabolism of Duloxetine can be decreased when combined with Oxamniquine.
Chlorpromazine The metabolism of Chlorpromazine can be decreased when combined with Oxamniquine.
Celecoxib The metabolism of Celecoxib can be decreased when combined with Oxamniquine.
Buspirone The metabolism of Buspirone can be decreased when combined with Oxamniquine.
Darifenacin The metabolism of Darifenacin can be decreased when combined with Oxamniquine.
Oxycodone The metabolism of Oxycodone can be decreased when combined with Oxamniquine.
Ritonavir The metabolism of Ritonavir can be decreased when combined with Oxamniquine.
Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Oxamniquine.
Cinnarizine The metabolism of Cinnarizine can be decreased when combined with Oxamniquine.
Propranolol The metabolism of Propranolol can be decreased when combined with Oxamniquine.
Lisuride The metabolism of Lisuride can be decreased when combined with Oxamniquine.
Doxazosin The metabolism of Doxazosin can be decreased when combined with Oxamniquine.
Piperazine The metabolism of Piperazine can be decreased when combined with Oxamniquine.
Labetalol The metabolism of Labetalol can be decreased when combined with Oxamniquine.
Chloroquine The metabolism of Chloroquine can be decreased when combined with Oxamniquine.
Imatinib The metabolism of Imatinib can be decreased when combined with Oxamniquine.
Simvastatin The metabolism of Simvastatin can be decreased when combined with Oxamniquine.
Dextropropoxyphene The metabolism of Dextropropoxyphene can be decreased when combined with Oxamniquine.
Trazodone The metabolism of Trazodone can be decreased when combined with Oxamniquine.
Galantamine The metabolism of Galantamine can be decreased when combined with Oxamniquine.
Thioridazine The metabolism of Thioridazine can be decreased when combined with Oxamniquine.
Nicergoline The metabolism of Nicergoline can be decreased when combined with Oxamniquine.
Amprenavir The metabolism of Amprenavir can be decreased when combined with Oxamniquine.
Delavirdine The metabolism of Delavirdine can be decreased when combined with Oxamniquine.
Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Oxamniquine.
Paroxetine The metabolism of Paroxetine can be decreased when combined with Oxamniquine.
Nateglinide The metabolism of Nateglinide can be decreased when combined with Oxamniquine.
Risperidone The metabolism of Risperidone can be decreased when combined with Oxamniquine.
Meclizine The metabolism of Meclizine can be decreased when combined with Oxamniquine.
Pentamidine The metabolism of Pentamidine can be decreased when combined with Oxamniquine.
Dolasetron The metabolism of Dolasetron can be decreased when combined with Oxamniquine.
Minaprine The metabolism of Minaprine can be decreased when combined with Oxamniquine.
Donepezil The metabolism of Donepezil can be decreased when combined with Oxamniquine.
Perphenazine The metabolism of Perphenazine can be decreased when combined with Oxamniquine.
Alprenolol The metabolism of Alprenolol can be decreased when combined with Oxamniquine.
Ondansetron The metabolism of Ondansetron can be decreased when combined with Oxamniquine.
Phenformin The metabolism of Phenformin can be decreased when combined with Oxamniquine.
Almotriptan The metabolism of Almotriptan can be decreased when combined with Oxamniquine.
Buprenorphine The metabolism of Buprenorphine can be decreased when combined with Oxamniquine.
Tipranavir The metabolism of Tipranavir can be decreased when combined with Oxamniquine.
Mesoridazine The metabolism of Mesoridazine can be decreased when combined with Oxamniquine.
Maprotiline The metabolism of Maprotiline can be decreased when combined with Oxamniquine.
Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Oxamniquine.
Pindolol The metabolism of Pindolol can be decreased when combined with Oxamniquine.
Azelastine The metabolism of Azelastine can be decreased when combined with Oxamniquine.
Formoterol The metabolism of Formoterol can be decreased when combined with Oxamniquine.
Methoxyflurane The metabolism of Methoxyflurane can be decreased when combined with Oxamniquine.
Tolterodine The metabolism of Tolterodine can be decreased when combined with Oxamniquine.
Selegiline The metabolism of Selegiline can be decreased when combined with Oxamniquine.
Promethazine The metabolism of Promethazine can be decreased when combined with Oxamniquine.
Mequitazine The metabolism of Mequitazine can be decreased when combined with Oxamniquine.
Perhexiline The metabolism of Perhexiline can be decreased when combined with Oxamniquine.
Diphenhydramine The metabolism of Diphenhydramine can be decreased when combined with Oxamniquine.
Tegaserod The metabolism of Tegaserod can be decreased when combined with Oxamniquine.
Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Oxamniquine.
Sertraline The metabolism of Sertraline can be decreased when combined with Oxamniquine.
Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Oxamniquine.
Nifedipine The metabolism of Nifedipine can be decreased when combined with Oxamniquine.
Carvedilol The metabolism of Carvedilol can be decreased when combined with Oxamniquine.
Nefazodone The metabolism of Nefazodone can be decreased when combined with Oxamniquine.

Target Protein

DNA

Referensi & Sumber

Artikel (PubMed)
  • PMID: 17134907
    Filho RP, de Souza Menezes CM, Pinto PL, Paula GA, Brandt CA, da Silveira MA: Design, synthesis, and in vivo evaluation of oxamniquine methacrylate and acrylamide prodrugs. Bioorg Med Chem. 2007 Feb 1;15(3):1229-36. Epub 2006 Nov 16.

Contoh Produk & Brand

Produk: 0 • International brands: 2
International Brands
  • Mansil
  • Vansil

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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