Oral, mouse: LD50 = 512 mg/kg; Oral, rat: LD50 = 890 mg/kg.
Pentolinium is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Alfuzosin | Alfuzosin may increase the hypotensive activities of Pentolinium. |
| Amifostine | Pentolinium may increase the hypotensive activities of Amifostine. |
| Diazoxide | Diazoxide may increase the hypotensive activities of Pentolinium. |
| Methylphenidate | Methylphenidate may decrease the antihypertensive activities of Pentolinium. |
| Dexmethylphenidate | Dexmethylphenidate may decrease the antihypertensive activities of Pentolinium. |
| Obinutuzumab | Pentolinium may increase the hypotensive activities of Obinutuzumab. |
| Pentoxifylline | Pentoxifylline may increase the hypotensive activities of Pentolinium. |
| Rituximab | Pentolinium may increase the hypotensive activities of Rituximab. |
| Desmopressin | Desmopressin may decrease the antihypertensive activities of Pentolinium. |
| Phentermine | Phentermine may decrease the antihypertensive activities of Pentolinium. |
| Midodrine | Midodrine may decrease the antihypertensive activities of Pentolinium. |
| Eletriptan | Eletriptan may decrease the antihypertensive activities of Pentolinium. |
| Isoetharine | Isoetharine may decrease the antihypertensive activities of Pentolinium. |
| Methysergide | Methysergide may decrease the antihypertensive activities of Pentolinium. |
| Cabergoline | Cabergoline may decrease the antihypertensive activities of Pentolinium. |
| Atomoxetine | Atomoxetine may decrease the antihypertensive activities of Pentolinium. |
| Etomidate | Etomidate may decrease the antihypertensive activities of Pentolinium. |
| Zolmitriptan | Zolmitriptan may decrease the antihypertensive activities of Pentolinium. |
| Dihydroergotamine | Dihydroergotamine may decrease the antihypertensive activities of Pentolinium. |
| Methylergometrine | Methylergometrine may decrease the antihypertensive activities of Pentolinium. |
| Norepinephrine | Norepinephrine may decrease the antihypertensive activities of Pentolinium. |
| Mirtazapine | Mirtazapine may decrease the antihypertensive activities of Pentolinium. |
| Phenylephrine | Phenylephrine may decrease the antihypertensive activities of Pentolinium. |
| Phenylpropanolamine | Phenylpropanolamine may decrease the antihypertensive activities of Pentolinium. |
| Promazine | Promazine may decrease the antihypertensive activities of Pentolinium. |
| Droperidol | Droperidol may decrease the antihypertensive activities of Pentolinium. |
| Buspirone | Buspirone may decrease the antihypertensive activities of Pentolinium. |
| Doxapram | Doxapram may decrease the antihypertensive activities of Pentolinium. |
| Atropine | Atropine may decrease the antihypertensive activities of Pentolinium. |
| Lisuride | Lisuride may decrease the antihypertensive activities of Pentolinium. |
| Metaraminol | Metaraminol may decrease the antihypertensive activities of Pentolinium. |
| Trazodone | Trazodone may decrease the antihypertensive activities of Pentolinium. |
| Epinephrine | Epinephrine may decrease the antihypertensive activities of Pentolinium. |
| Ergotamine | Ergotamine may decrease the antihypertensive activities of Pentolinium. |
| Nicergoline | Nicergoline may decrease the antihypertensive activities of Pentolinium. |
| Methoxamine | Methoxamine may decrease the antihypertensive activities of Pentolinium. |
| Risperidone | Risperidone may decrease the antihypertensive activities of Pentolinium. |
| Propiomazine | Propiomazine may decrease the antihypertensive activities of Pentolinium. |
| Orciprenaline | Orciprenaline may decrease the antihypertensive activities of Pentolinium. |
| Phenmetrazine | Phenmetrazine may decrease the antihypertensive activities of Pentolinium. |
| Trifluoperazine | Trifluoperazine may decrease the antihypertensive activities of Pentolinium. |
| Dobutamine | Dobutamine may decrease the antihypertensive activities of Pentolinium. |
| Pseudoephedrine | Pseudoephedrine may decrease the antihypertensive activities of Pentolinium. |
| Benzphetamine | Benzphetamine may decrease the antihypertensive activities of Pentolinium. |
| Ritodrine | Ritodrine may decrease the antihypertensive activities of Pentolinium. |
| Flupentixol | Flupentixol may decrease the antihypertensive activities of Pentolinium. |
| Bitolterol | Bitolterol may decrease the antihypertensive activities of Pentolinium. |
| Almotriptan | Almotriptan may decrease the antihypertensive activities of Pentolinium. |
| Diethylpropion | Diethylpropion may decrease the antihypertensive activities of Pentolinium. |
| Salmeterol | Salmeterol may decrease the antihypertensive activities of Pentolinium. |
| Naratriptan | Naratriptan may decrease the antihypertensive activities of Pentolinium. |
| Rizatriptan | Rizatriptan may decrease the antihypertensive activities of Pentolinium. |
| Formoterol | Formoterol may decrease the antihypertensive activities of Pentolinium. |
| Dopamine | Dopamine may decrease the antihypertensive activities of Pentolinium. |
| Frovatriptan | Frovatriptan may decrease the antihypertensive activities of Pentolinium. |
| Albuterol | Salbutamol may decrease the antihypertensive activities of Pentolinium. |
| Methoxyflurane | Methoxyflurane may decrease the antihypertensive activities of Pentolinium. |
| Ergoloid mesylate | Ergoloid mesylate may decrease the antihypertensive activities of Pentolinium. |
| Isoprenaline | Isoprenaline may decrease the antihypertensive activities of Pentolinium. |
| Arbutamine | Arbutamine may decrease the antihypertensive activities of Pentolinium. |
| Dutasteride | Dutasteride may decrease the antihypertensive activities of Pentolinium. |
| Nefazodone | Nefazodone may decrease the antihypertensive activities of Pentolinium. |
| Propafenone | Propafenone may decrease the antihypertensive activities of Pentolinium. |
| Pergolide | Pergolide may decrease the antihypertensive activities of Pentolinium. |
| Finasteride | Finasteride may decrease the antihypertensive activities of Pentolinium. |
| Ergometrine | Ergometrine may decrease the antihypertensive activities of Pentolinium. |
| Lisdexamfetamine | Lisdexamfetamine may decrease the antihypertensive activities of Pentolinium. |
| Paliperidone | Paliperidone may decrease the antihypertensive activities of Pentolinium. |
| Arformoterol | Arformoterol may decrease the antihypertensive activities of Pentolinium. |
| Fenoterol | Fenoterol may decrease the antihypertensive activities of Pentolinium. |
| Pirbuterol | Pirbuterol may decrease the antihypertensive activities of Pentolinium. |
| Ephedra sinica root | Ephedra sinica root may decrease the antihypertensive activities of Pentolinium. |
| Ephedrine | Ephedrine may decrease the antihypertensive activities of Pentolinium. |
| Mephentermine | Mephentermine may decrease the antihypertensive activities of Pentolinium. |
| Procaterol | Procaterol may decrease the antihypertensive activities of Pentolinium. |
| Yohimbine | Yohimbine may decrease the antihypertensive activities of Pentolinium. |
| Methotrimeprazine | Methotrimeprazine may decrease the antihypertensive activities of Pentolinium. |
| Clenbuterol | Clenbuterol may decrease the antihypertensive activities of Pentolinium. |
| MMDA | MMDA may decrease the antihypertensive activities of Pentolinium. |
| Midomafetamine | Midomafetamine may decrease the antihypertensive activities of Pentolinium. |
| 2,5-Dimethoxy-4-ethylamphetamine | 2,5-Dimethoxy-4-ethylamphetamine may decrease the antihypertensive activities of Pentolinium. |
| 4-Methoxyamphetamine | 4-Methoxyamphetamine may decrease the antihypertensive activities of Pentolinium. |
| 4-Bromo-2,5-dimethoxyamphetamine | 4-Bromo-2,5-dimethoxyamphetamine may decrease the antihypertensive activities of Pentolinium. |
| Tenamfetamine | Tenamfetamine may decrease the antihypertensive activities of Pentolinium. |
| Chlorphentermine | Chlorphentermine may decrease the antihypertensive activities of Pentolinium. |
| Dextroamphetamine | Dextroamphetamine may decrease the antihypertensive activities of Pentolinium. |
| Metamfetamine | Metamfetamine may decrease the antihypertensive activities of Pentolinium. |
| Phendimetrazine | Phendimetrazine may decrease the antihypertensive activities of Pentolinium. |
| Solifenacin | Solifenacin may decrease the antihypertensive activities of Pentolinium. |
| Periciazine | Periciazine may decrease the antihypertensive activities of Pentolinium. |
| Acepromazine | Acepromazine may decrease the antihypertensive activities of Pentolinium. |
| Thioproperazine | Thioproperazine may decrease the antihypertensive activities of Pentolinium. |
| Zuclopenthixol | Zuclopenthixol may decrease the antihypertensive activities of Pentolinium. |
| Epicaptopril | Epicaptopril may decrease the antihypertensive activities of Pentolinium. |
| 1-benzylimidazole | 1-benzylimidazole may decrease the antihypertensive activities of Pentolinium. |
| Lysergic acid diethylamide | Lysergic acid diethylamide may decrease the antihypertensive activities of Pentolinium. |
| Dronedarone | Dronedarone may decrease the antihypertensive activities of Pentolinium. |
| Flibanserin | Flibanserin may decrease the antihypertensive activities of Pentolinium. |
| Iloperidone | Iloperidone may decrease the antihypertensive activities of Pentolinium. |
| Indacaterol | Indacaterol may decrease the antihypertensive activities of Pentolinium. |