Peringatan Keamanan

Symptoms of overdose include dizziness or drowsiness (severe), flushing of skin, pinpoint pupils of eyes and slowed pulse.

Deserpidine

DB01089

small molecule approved

Deskripsi

Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.

Struktur Molekul 2D

Berat 578.6527
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

632 Data
Alfuzosin Alfuzosin may increase the hypotensive activities of Deserpidine.
Amifostine Deserpidine may increase the hypotensive activities of Amifostine.
Diazoxide Diazoxide may increase the hypotensive activities of Deserpidine.
Methylphenidate Methylphenidate may decrease the antihypertensive activities of Deserpidine.
Dexmethylphenidate Dexmethylphenidate may decrease the antihypertensive activities of Deserpidine.
Obinutuzumab Deserpidine may increase the hypotensive activities of Obinutuzumab.
Pentoxifylline Pentoxifylline may increase the hypotensive activities of Deserpidine.
Rituximab Deserpidine may increase the hypotensive activities of Rituximab.
Desmopressin Desmopressin may decrease the antihypertensive activities of Deserpidine.
Cyclosporine Cyclosporine may decrease the antihypertensive activities of Deserpidine.
Phentermine Phentermine may decrease the antihypertensive activities of Deserpidine.
Midodrine Midodrine may decrease the antihypertensive activities of Deserpidine.
Eletriptan Eletriptan may decrease the antihypertensive activities of Deserpidine.
Isoetharine Isoetharine may decrease the antihypertensive activities of Deserpidine.
Methysergide Methysergide may decrease the antihypertensive activities of Deserpidine.
Cabergoline Cabergoline may decrease the antihypertensive activities of Deserpidine.
Atomoxetine Atomoxetine may decrease the antihypertensive activities of Deserpidine.
Etomidate Etomidate may decrease the antihypertensive activities of Deserpidine.
Zolmitriptan Zolmitriptan may decrease the antihypertensive activities of Deserpidine.
Dihydroergotamine Dihydroergotamine may decrease the antihypertensive activities of Deserpidine.
Amitriptyline Amitriptyline may decrease the antihypertensive activities of Deserpidine.
Protriptyline Protriptyline may decrease the antihypertensive activities of Deserpidine.
Methylergometrine Methylergometrine may decrease the antihypertensive activities of Deserpidine.
Norepinephrine Norepinephrine may decrease the antihypertensive activities of Deserpidine.
Mirtazapine Mirtazapine may decrease the antihypertensive activities of Deserpidine.
Phenylephrine Phenylephrine may decrease the antihypertensive activities of Deserpidine.
Phenylpropanolamine Phenylpropanolamine may decrease the antihypertensive activities of Deserpidine.
Promazine Promazine may decrease the antihypertensive activities of Deserpidine.
Droperidol Droperidol may decrease the antihypertensive activities of Deserpidine.
Buspirone Buspirone may decrease the antihypertensive activities of Deserpidine.
Nortriptyline Nortriptyline may decrease the antihypertensive activities of Deserpidine.
Amoxapine Amoxapine may decrease the antihypertensive activities of Deserpidine.
Doxapram Doxapram may decrease the antihypertensive activities of Deserpidine.
Atropine Atropine may decrease the antihypertensive activities of Deserpidine.
Lisuride Lisuride may decrease the antihypertensive activities of Deserpidine.
Metaraminol Metaraminol may decrease the antihypertensive activities of Deserpidine.
Trazodone Trazodone may decrease the antihypertensive activities of Deserpidine.
Epinephrine Epinephrine may decrease the antihypertensive activities of Deserpidine.
Sumatriptan Sumatriptan may decrease the antihypertensive activities of Deserpidine.
Ergotamine Ergotamine may decrease the antihypertensive activities of Deserpidine.
Nicergoline Nicergoline may decrease the antihypertensive activities of Deserpidine.
Methoxamine Methoxamine may decrease the antihypertensive activities of Deserpidine.
Trimipramine Trimipramine may decrease the antihypertensive activities of Deserpidine.
Risperidone Risperidone may decrease the antihypertensive activities of Deserpidine.
Propiomazine Propiomazine may decrease the antihypertensive activities of Deserpidine.
Alfentanil Alfentanil may decrease the antihypertensive activities of Deserpidine.
Fentanyl Fentanyl may decrease the antihypertensive activities of Deserpidine.
Orciprenaline Orciprenaline may decrease the antihypertensive activities of Deserpidine.
Phenmetrazine Phenmetrazine may decrease the antihypertensive activities of Deserpidine.
Trifluoperazine Trifluoperazine may decrease the antihypertensive activities of Deserpidine.
Dobutamine Dobutamine may decrease the antihypertensive activities of Deserpidine.
Pseudoephedrine Pseudoephedrine may decrease the antihypertensive activities of Deserpidine.
Benzphetamine Benzphetamine may decrease the antihypertensive activities of Deserpidine.
Ritodrine Ritodrine may decrease the antihypertensive activities of Deserpidine.
Terbutaline Terbutaline may decrease the antihypertensive activities of Deserpidine.
Flupentixol Flupentixol may decrease the antihypertensive activities of Deserpidine.
Bitolterol Bitolterol may decrease the antihypertensive activities of Deserpidine.
Quinidine Quinidine may decrease the antihypertensive activities of Deserpidine.
Almotriptan Almotriptan may decrease the antihypertensive activities of Deserpidine.
Diethylpropion Diethylpropion may decrease the antihypertensive activities of Deserpidine.
Salmeterol Salmeterol may decrease the antihypertensive activities of Deserpidine.
Naratriptan Naratriptan may decrease the antihypertensive activities of Deserpidine.
Rizatriptan Rizatriptan may decrease the antihypertensive activities of Deserpidine.
Formoterol Formoterol may decrease the antihypertensive activities of Deserpidine.
Dopamine Dopamine may decrease the antihypertensive activities of Deserpidine.
Frovatriptan Frovatriptan may decrease the antihypertensive activities of Deserpidine.
Albuterol Salbutamol may decrease the antihypertensive activities of Deserpidine.
Methoxyflurane Methoxyflurane may decrease the antihypertensive activities of Deserpidine.
Ergoloid mesylate Ergoloid mesylate may decrease the antihypertensive activities of Deserpidine.
Isoprenaline Isoprenaline may decrease the antihypertensive activities of Deserpidine.
Arbutamine Arbutamine may decrease the antihypertensive activities of Deserpidine.
Dutasteride Dutasteride may decrease the antihypertensive activities of Deserpidine.
Doxepin Doxepin may decrease the antihypertensive activities of Deserpidine.
Nefazodone Nefazodone may decrease the antihypertensive activities of Deserpidine.
Desipramine Desipramine may decrease the antihypertensive activities of Deserpidine.
Pergolide Pergolide may decrease the antihypertensive activities of Deserpidine.
Finasteride Finasteride may decrease the antihypertensive activities of Deserpidine.
Ergometrine Ergometrine may decrease the antihypertensive activities of Deserpidine.
Lisdexamfetamine Lisdexamfetamine may decrease the antihypertensive activities of Deserpidine.
Paliperidone Paliperidone may decrease the antihypertensive activities of Deserpidine.
Arformoterol Arformoterol may decrease the antihypertensive activities of Deserpidine.
Fenoterol Fenoterol may decrease the antihypertensive activities of Deserpidine.
Pirbuterol Pirbuterol may decrease the antihypertensive activities of Deserpidine.
Ephedra sinica root Ephedra sinica root may decrease the antihypertensive activities of Deserpidine.
Ephedrine Ephedrine may decrease the antihypertensive activities of Deserpidine.
Mephentermine Mephentermine may decrease the antihypertensive activities of Deserpidine.
Procaterol Procaterol may decrease the antihypertensive activities of Deserpidine.
Yohimbine Yohimbine may decrease the antihypertensive activities of Deserpidine.
Methotrimeprazine Methotrimeprazine may decrease the antihypertensive activities of Deserpidine.
Clenbuterol Clenbuterol may decrease the antihypertensive activities of Deserpidine.
Bambuterol Bambuterol may decrease the antihypertensive activities of Deserpidine.
MMDA MMDA may decrease the antihypertensive activities of Deserpidine.
Midomafetamine Midomafetamine may decrease the antihypertensive activities of Deserpidine.
2,5-Dimethoxy-4-ethylamphetamine 2,5-Dimethoxy-4-ethylamphetamine may decrease the antihypertensive activities of Deserpidine.
4-Methoxyamphetamine 4-Methoxyamphetamine may decrease the antihypertensive activities of Deserpidine.
4-Bromo-2,5-dimethoxyamphetamine 4-Bromo-2,5-dimethoxyamphetamine may decrease the antihypertensive activities of Deserpidine.
Tenamfetamine Tenamfetamine may decrease the antihypertensive activities of Deserpidine.
Chlorphentermine Chlorphentermine may decrease the antihypertensive activities of Deserpidine.
Dextroamphetamine Dextroamphetamine may decrease the antihypertensive activities of Deserpidine.
Metamfetamine Metamfetamine may decrease the antihypertensive activities of Deserpidine.

Target Protein

Synaptic vesicular amine transporter SLC18A2
Angiotensin-converting enzyme ACE

Referensi & Sumber

Synthesis reference: Gabriele Fontana, Ezio Bombardelli, Cristian Samori, Eleonora Baldelli, Andrea Guerrini, Arturo Battaglia, Bruno Danieli, "Process for the Semisynthesis of Deserpidine." U.S. Patent US20080242864, issued October 02, 2008.

Contoh Produk & Brand

Produk: 3 • International brands: 2
Produk
  • Enduronyl
    Tablet • - • Oral • US • Approved
  • Enduronyl
    Tablet • - • Oral • US • Approved
  • Enduronyl Forte
    Tablet • - • Oral • US • Approved
International Brands
  • Halmonyl
  • Harmonyl — Abbott

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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