Azlocillin

DB01061

small molecule approved

Deskripsi

Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin.

Struktur Molekul 2D

Berat 461.492
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) Mean elimination half-life is 1.3 to 1.5 hours. Longer in neonates, and 2 to 6 hours in patients with renal impairment.
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Not significantly absorbed from the gastrointestinal tract.

Metabolisme

Eliminated predominantly by renal mechanisms, but also undergoes biotransformation within body tissues and intraintestinal degradation by bowel bacteria, with high concentrations found in bile.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

284 Data
Methotrexate The excretion of Methotrexate can be decreased when combined with Azlocillin.
Probenecid The excretion of Azlocillin can be decreased when combined with Probenecid.
Doxycycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Doxycycline.
Lymecycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Lymecycline.
Clomocycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Clomocycline.
Tigecycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Tigecycline.
Oxytetracycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Oxytetracycline.
Demeclocycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Demeclocycline.
Tetracycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Tetracycline.
Metacycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Metacycline.
Minocycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Minocycline.
Rolitetracycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Rolitetracycline.
Sarecycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Sarecycline.
Eravacycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Eravacycline.
Omadacycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Omadacycline.
Penimepicycline The therapeutic efficacy of Azlocillin can be decreased when used in combination with Penimepicycline.
Mycophenolate mofetil The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Azlocillin.
Mycophenolic acid The serum concentration of Mycophenolic acid can be decreased when it is combined with Azlocillin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Azlocillin.
Dicoumarol Azlocillin may increase the anticoagulant activities of Dicoumarol.
Phenindione Azlocillin may increase the anticoagulant activities of Phenindione.
Warfarin Azlocillin may increase the anticoagulant activities of Warfarin.
Phenprocoumon Azlocillin may increase the anticoagulant activities of Phenprocoumon.
Acenocoumarol Azlocillin may increase the anticoagulant activities of Acenocoumarol.
4-hydroxycoumarin Azlocillin may increase the anticoagulant activities of 4-hydroxycoumarin.
Coumarin Azlocillin may increase the anticoagulant activities of Coumarin.
(R)-warfarin Azlocillin may increase the anticoagulant activities of (R)-warfarin.
Ethyl biscoumacetate Azlocillin may increase the anticoagulant activities of Ethyl biscoumacetate.
Fluindione Azlocillin may increase the anticoagulant activities of Fluindione.
Clorindione Azlocillin may increase the anticoagulant activities of Clorindione.
Diphenadione Azlocillin may increase the anticoagulant activities of Diphenadione.
Tioclomarol Azlocillin may increase the anticoagulant activities of Tioclomarol.
(S)-Warfarin Azlocillin may increase the anticoagulant activities of (S)-Warfarin.
Diethylstilbestrol The therapeutic efficacy of Diethylstilbestrol can be decreased when used in combination with Azlocillin.
Etonogestrel The therapeutic efficacy of Etonogestrel can be decreased when used in combination with Azlocillin.
Desogestrel The therapeutic efficacy of Desogestrel can be decreased when used in combination with Azlocillin.
Megestrol acetate The therapeutic efficacy of Megestrol acetate can be decreased when used in combination with Azlocillin.
Levonorgestrel The therapeutic efficacy of Levonorgestrel can be decreased when used in combination with Azlocillin.
Progesterone The therapeutic efficacy of Progesterone can be decreased when used in combination with Azlocillin.
Medroxyprogesterone acetate The therapeutic efficacy of Medroxyprogesterone acetate can be decreased when used in combination with Azlocillin.
Norethisterone The therapeutic efficacy of Norethisterone can be decreased when used in combination with Azlocillin.
Estradiol The therapeutic efficacy of Estradiol can be decreased when used in combination with Azlocillin.
Ethynodiol diacetate The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Azlocillin.
Mifepristone The therapeutic efficacy of Mifepristone can be decreased when used in combination with Azlocillin.
Norgestimate The therapeutic efficacy of Norgestimate can be decreased when used in combination with Azlocillin.
Ethinylestradiol The therapeutic efficacy of Ethinylestradiol can be decreased when used in combination with Azlocillin.
Mestranol The therapeutic efficacy of Mestranol can be decreased when used in combination with Azlocillin.
Drospirenone The therapeutic efficacy of Drospirenone can be decreased when used in combination with Azlocillin.
Estrone sulfate The therapeutic efficacy of Estrone sulfate can be decreased when used in combination with Azlocillin.
Octylphenoxy polyethoxyethanol The therapeutic efficacy of Octylphenoxy polyethoxyethanol can be decreased when used in combination with Azlocillin.
Cyproterone acetate The therapeutic efficacy of Cyproterone acetate can be decreased when used in combination with Azlocillin.
Trestolone The therapeutic efficacy of Trestolone can be decreased when used in combination with Azlocillin.
Norelgestromin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Azlocillin.
Gestodene The therapeutic efficacy of Gestodene can be decreased when used in combination with Azlocillin.
Hydroxyprogesterone caproate The therapeutic efficacy of Hydroxyprogesterone caproate can be decreased when used in combination with Azlocillin.
Ulipristal The therapeutic efficacy of Ulipristal can be decreased when used in combination with Azlocillin.
Dienogest The therapeutic efficacy of Dienogest can be decreased when used in combination with Azlocillin.
Norethynodrel The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Azlocillin.
Norgestrel The therapeutic efficacy of Norgestrel can be decreased when used in combination with Azlocillin.
Cloprostenol The therapeutic efficacy of Cloprostenol can be decreased when used in combination with Azlocillin.
Gestrinone The therapeutic efficacy of Gestrinone can be decreased when used in combination with Azlocillin.
Nomegestrol The therapeutic efficacy of Nomegestrol can be decreased when used in combination with Azlocillin.
Lynestrenol The therapeutic efficacy of Lynestrenol can be decreased when used in combination with Azlocillin.
Gossypol The therapeutic efficacy of Gossypol can be decreased when used in combination with Azlocillin.
Ormeloxifene The therapeutic efficacy of Ormeloxifene can be decreased when used in combination with Azlocillin.
Chlormadinone The therapeutic efficacy of Chlormadinone can be decreased when used in combination with Azlocillin.
Norgestrienone The therapeutic efficacy of Norgestrienone can be decreased when used in combination with Azlocillin.
Quingestanol The therapeutic efficacy of Quingestanol can be decreased when used in combination with Azlocillin.
Demegestone The therapeutic efficacy of Demegestone can be decreased when used in combination with Azlocillin.
Etynodiol The therapeutic efficacy of Etynodiol can be decreased when used in combination with Azlocillin.
Testosterone enanthate The therapeutic efficacy of Testosterone enanthate can be decreased when used in combination with Azlocillin.
Estradiol benzoate The therapeutic efficacy of Estradiol benzoate can be decreased when used in combination with Azlocillin.
Estradiol cypionate The therapeutic efficacy of Estradiol cypionate can be decreased when used in combination with Azlocillin.
Estradiol valerate The therapeutic efficacy of Estradiol valerate can be decreased when used in combination with Azlocillin.
Nomegestrol acetate The therapeutic efficacy of Nomegestrol acetate can be decreased when used in combination with Azlocillin.
Norethindrone enanthate The therapeutic efficacy of Norethindrone enanthate can be decreased when used in combination with Azlocillin.
Capreomycin The serum concentration of Capreomycin can be decreased when it is combined with Azlocillin.
Framycetin The serum concentration of Framycetin can be decreased when it is combined with Azlocillin.
Amikacin The serum concentration of Amikacin can be decreased when it is combined with Azlocillin.
Tobramycin The serum concentration of Tobramycin can be decreased when it is combined with Azlocillin.
Gentamicin The serum concentration of Gentamicin can be decreased when it is combined with Azlocillin.
Netilmicin The serum concentration of Netilmicin can be decreased when it is combined with Azlocillin.
Neomycin The serum concentration of Neomycin can be decreased when it is combined with Azlocillin.
Streptomycin The serum concentration of Streptomycin can be decreased when it is combined with Azlocillin.
Kanamycin The serum concentration of Kanamycin can be decreased when it is combined with Azlocillin.
Paromomycin The serum concentration of Paromomycin can be decreased when it is combined with Azlocillin.
Ribostamycin The serum concentration of Ribostamycin can be decreased when it is combined with Azlocillin.
Geneticin The serum concentration of Geneticin can be decreased when it is combined with Azlocillin.
Apramycin The serum concentration of Apramycin can be decreased when it is combined with Azlocillin.
Gentamicin C1a The serum concentration of Gentamicin C1a can be decreased when it is combined with Azlocillin.
Neamine The serum concentration of Neamine can be decreased when it is combined with Azlocillin.
Arbekacin The serum concentration of Arbekacin can be decreased when it is combined with Azlocillin.
Puromycin The serum concentration of Puromycin can be decreased when it is combined with Azlocillin.
Dihydrostreptomycin The serum concentration of Dihydrostreptomycin can be decreased when it is combined with Azlocillin.
Hygromycin B The serum concentration of Hygromycin B can be decreased when it is combined with Azlocillin.
Sisomicin The serum concentration of Sisomicin can be decreased when it is combined with Azlocillin.
Plazomicin The serum concentration of Plazomicin can be decreased when it is combined with Azlocillin.
Isepamicin The serum concentration of Isepamicin can be decreased when it is combined with Azlocillin.
Colistin The serum concentration of Colistin can be decreased when it is combined with Azlocillin.
BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Azlocillin.

Target Protein

Penicillin-binding protein 1A pbpA

Referensi & Sumber

Artikel (PubMed)
  • PMID: 10090000
    Wright AJ: The penicillins. Mayo Clin Proc. 1999 Mar;74(3):290-307.

Contoh Produk & Brand

Produk: 0 • International brands: 2
International Brands
  • Azlin
  • Securopen

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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