Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Duloxetine | The risk or severity of orthostatic hypotension and syncope can be increased when Nitrendipine is combined with Duloxetine. |
| Levodopa | The risk or severity of hypotension and orthostatic hypotension can be increased when Nitrendipine is combined with Levodopa. |
| Risperidone | Nitrendipine may increase the hypotensive activities of Risperidone. |
| Troglitazone | Troglitazone may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Reserpine | Reserpine may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Progesterone | Progesterone may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Chlorpromazine | Chlorpromazine may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Bosentan | Bosentan may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Ethinylestradiol | Ethinylestradiol may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Glyburide | Glyburide may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Cholic Acid | Cholic Acid may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Fusidic acid | Fusidic acid may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Simeprevir | Simeprevir may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Lenvatinib | Lenvatinib may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Letermovir | The metabolism of Nitrendipine can be decreased when combined with Letermovir. |
| Valinomycin | Valinomycin may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Olmesartan | Olmesartan may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Pralsetinib | Pralsetinib may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Ceritinib | Nitrendipine may increase the bradycardic activities of Ceritinib. |
| Ivabradine | Nitrendipine may increase the bradycardic activities of Ivabradine. |
| Ruxolitinib | Ruxolitinib may increase the bradycardic activities of Nitrendipine. |
| Alfuzosin | Alfuzosin may increase the hypotensive activities of Nitrendipine. |
| Amifostine | Nitrendipine may increase the hypotensive activities of Amifostine. |
| Diazoxide | Diazoxide may increase the hypotensive activities of Nitrendipine. |
| Methylphenidate | Methylphenidate may decrease the antihypertensive activities of Nitrendipine. |
| Dexmethylphenidate | Dexmethylphenidate may decrease the antihypertensive activities of Nitrendipine. |
| Obinutuzumab | Nitrendipine may increase the hypotensive activities of Obinutuzumab. |
| Pentoxifylline | Pentoxifylline may increase the hypotensive activities of Nitrendipine. |
| Rituximab | Nitrendipine may increase the hypotensive activities of Rituximab. |
| Desmopressin | Desmopressin may decrease the antihypertensive activities of Nitrendipine. |
| Isoetharine | Isoetharine may decrease the antihypertensive activities of Nitrendipine. |
| Etomidate | Etomidate may decrease the antihypertensive activities of Nitrendipine. |
| Zolmitriptan | Zolmitriptan may decrease the antihypertensive activities of Nitrendipine. |
| Norepinephrine | Norepinephrine may decrease the antihypertensive activities of Nitrendipine. |
| Phenylpropanolamine | Phenylpropanolamine may decrease the antihypertensive activities of Nitrendipine. |
| Doxapram | Doxapram may decrease the antihypertensive activities of Nitrendipine. |
| Metaraminol | Metaraminol may decrease the antihypertensive activities of Nitrendipine. |
| Methoxamine | Methoxamine may decrease the antihypertensive activities of Nitrendipine. |
| Orciprenaline | Orciprenaline may decrease the antihypertensive activities of Nitrendipine. |
| Phenmetrazine | Phenmetrazine may decrease the antihypertensive activities of Nitrendipine. |
| Dobutamine | Dobutamine may decrease the antihypertensive activities of Nitrendipine. |
| Pseudoephedrine | Pseudoephedrine may decrease the antihypertensive activities of Nitrendipine. |
| Ritodrine | Ritodrine may decrease the antihypertensive activities of Nitrendipine. |
| Bitolterol | Bitolterol may decrease the antihypertensive activities of Nitrendipine. |
| Diethylpropion | Diethylpropion may decrease the antihypertensive activities of Nitrendipine. |
| Naratriptan | Naratriptan may decrease the antihypertensive activities of Nitrendipine. |
| Rizatriptan | Rizatriptan may decrease the antihypertensive activities of Nitrendipine. |
| Dopamine | Dopamine may decrease the antihypertensive activities of Nitrendipine. |
| Frovatriptan | Frovatriptan may decrease the antihypertensive activities of Nitrendipine. |
| Isoprenaline | Isoprenaline may decrease the antihypertensive activities of Nitrendipine. |
| Arbutamine | Arbutamine may decrease the antihypertensive activities of Nitrendipine. |
| Lisdexamfetamine | Lisdexamfetamine may decrease the antihypertensive activities of Nitrendipine. |
| Fenoterol | Fenoterol may decrease the antihypertensive activities of Nitrendipine. |
| Pirbuterol | Pirbuterol may decrease the antihypertensive activities of Nitrendipine. |
| Ephedra sinica root | Ephedra sinica root may decrease the antihypertensive activities of Nitrendipine. |
| Ephedrine | Ephedrine may decrease the antihypertensive activities of Nitrendipine. |
| Mephentermine | Mephentermine may decrease the antihypertensive activities of Nitrendipine. |
| Procaterol | Procaterol may decrease the antihypertensive activities of Nitrendipine. |
| Clenbuterol | Clenbuterol may decrease the antihypertensive activities of Nitrendipine. |
| Bambuterol | Bambuterol may decrease the antihypertensive activities of Nitrendipine. |
| MMDA | MMDA may decrease the antihypertensive activities of Nitrendipine. |
| Midomafetamine | Midomafetamine may decrease the antihypertensive activities of Nitrendipine. |
| 2,5-Dimethoxy-4-ethylamphetamine | 2,5-Dimethoxy-4-ethylamphetamine may decrease the antihypertensive activities of Nitrendipine. |
| 4-Methoxyamphetamine | 4-Methoxyamphetamine may decrease the antihypertensive activities of Nitrendipine. |
| 4-Bromo-2,5-dimethoxyamphetamine | 4-Bromo-2,5-dimethoxyamphetamine may decrease the antihypertensive activities of Nitrendipine. |
| Tenamfetamine | Tenamfetamine may decrease the antihypertensive activities of Nitrendipine. |
| Chlorphentermine | Chlorphentermine may decrease the antihypertensive activities of Nitrendipine. |
| Dextroamphetamine | Dextroamphetamine may decrease the antihypertensive activities of Nitrendipine. |
| Metamfetamine | Metamfetamine may decrease the antihypertensive activities of Nitrendipine. |
| Phendimetrazine | Phendimetrazine may decrease the antihypertensive activities of Nitrendipine. |
| Epicaptopril | Epicaptopril may decrease the antihypertensive activities of Nitrendipine. |
| 1-benzylimidazole | 1-benzylimidazole may decrease the antihypertensive activities of Nitrendipine. |
| Amineptine | Amineptine may decrease the antihypertensive activities of Nitrendipine. |
| Amibegron | Amibegron may decrease the antihypertensive activities of Nitrendipine. |
| Naluzotan | Naluzotan may decrease the antihypertensive activities of Nitrendipine. |
| Solabegron | Solabegron may decrease the antihypertensive activities of Nitrendipine. |
| Droxidopa | Droxidopa may decrease the antihypertensive activities of Nitrendipine. |
| Esmirtazapine | Esmirtazapine may decrease the antihypertensive activities of Nitrendipine. |
| Nitrous oxide | Nitrous oxide may decrease the antihypertensive activities of Nitrendipine. |
| Isometheptene | Isometheptene may decrease the antihypertensive activities of Nitrendipine. |
| Levonordefrin | Levonordefrin may decrease the antihypertensive activities of Nitrendipine. |
| Naphazoline | Naphazoline may decrease the antihypertensive activities of Nitrendipine. |
| Tetryzoline | Tetryzoline may decrease the antihypertensive activities of Nitrendipine. |
| Cinitapride | Cinitapride may decrease the antihypertensive activities of Nitrendipine. |
| Tyramine | Tyramine may decrease the antihypertensive activities of Nitrendipine. |
| Adrafinil | Adrafinil may decrease the antihypertensive activities of Nitrendipine. |
| Ifenprodil | Ifenprodil may decrease the antihypertensive activities of Nitrendipine. |
| Hexoprenaline | Hexoprenaline may decrease the antihypertensive activities of Nitrendipine. |
| Etilefrine | Etilefrine may decrease the antihypertensive activities of Nitrendipine. |
| Dimetacrine | Dimetacrine may decrease the antihypertensive activities of Nitrendipine. |
| Cirazoline | Cirazoline may decrease the antihypertensive activities of Nitrendipine. |
| Synephrine | Synephrine may decrease the antihypertensive activities of Nitrendipine. |
| Moxisylyte | Moxisylyte may decrease the antihypertensive activities of Nitrendipine. |
| Oxaprotiline | Oxaprotiline may decrease the antihypertensive activities of Nitrendipine. |
| Iofetamine I-123 | Iofetamine I-123 may decrease the antihypertensive activities of Nitrendipine. |
| Racepinephrine | Racepinephrine may decrease the antihypertensive activities of Nitrendipine. |
| DL-Methylephedrine | DL-Methylephedrine may decrease the antihypertensive activities of Nitrendipine. |
| Amitraz | Amitraz may decrease the antihypertensive activities of Nitrendipine. |
| Medetomidine | Medetomidine may decrease the antihypertensive activities of Nitrendipine. |
| Xylazine | Xylazine may decrease the antihypertensive activities of Nitrendipine. |