Oral Rat LD50 = 5600 mg/kg, oral Mouse LD50 = 2600 mg/kg
A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Alfuzosin | Alfuzosin may increase the hypotensive activities of Trichlormethiazide. |
| Amifostine | Trichlormethiazide may increase the hypotensive activities of Amifostine. |
| Diazoxide | Diazoxide may increase the hypotensive activities of Trichlormethiazide. |
| Forasartan | Trichlormethiazide may increase the hypotensive and Electrolyte Disturbance activities of Forasartan. |
| Tasosartan | Trichlormethiazide may increase the hypotensive and Electrolyte Disturbance activities of Tasosartan. |
| Saralasin | Trichlormethiazide may increase the hypotensive and Electrolyte Disturbance activities of Saralasin. |
| Fimasartan | Trichlormethiazide may increase the hypotensive and Electrolyte Disturbance activities of Fimasartan. |
| Methylphenidate | Methylphenidate may decrease the antihypertensive activities of Trichlormethiazide. |
| Dexmethylphenidate | Dexmethylphenidate may decrease the antihypertensive activities of Trichlormethiazide. |
| Obinutuzumab | Trichlormethiazide may increase the hypotensive activities of Obinutuzumab. |
| Pentoxifylline | Pentoxifylline may increase the hypotensive activities of Trichlormethiazide. |
| Rituximab | Trichlormethiazide may increase the hypotensive activities of Rituximab. |
| Phentermine | Phentermine may decrease the antihypertensive activities of Trichlormethiazide. |
| Midodrine | Midodrine may decrease the antihypertensive activities of Trichlormethiazide. |
| Eletriptan | Eletriptan may decrease the antihypertensive activities of Trichlormethiazide. |
| Methysergide | Methysergide may decrease the antihypertensive activities of Trichlormethiazide. |
| Cabergoline | Cabergoline may decrease the antihypertensive activities of Trichlormethiazide. |
| Zolmitriptan | Zolmitriptan may decrease the antihypertensive activities of Trichlormethiazide. |
| Dihydroergotamine | Dihydroergotamine may decrease the antihypertensive activities of Trichlormethiazide. |
| Protriptyline | Protriptyline may decrease the antihypertensive activities of Trichlormethiazide. |
| Methylergometrine | Methylergometrine may decrease the antihypertensive activities of Trichlormethiazide. |
| Mirtazapine | Mirtazapine may decrease the antihypertensive activities of Trichlormethiazide. |
| Phenylephrine | Phenylephrine may decrease the antihypertensive activities of Trichlormethiazide. |
| Droperidol | Droperidol may decrease the antihypertensive activities of Trichlormethiazide. |
| Doxapram | Doxapram may decrease the antihypertensive activities of Trichlormethiazide. |
| Lisuride | Lisuride may decrease the antihypertensive activities of Trichlormethiazide. |
| Metaraminol | Metaraminol may decrease the antihypertensive activities of Trichlormethiazide. |
| Ergotamine | Ergotamine may decrease the antihypertensive activities of Trichlormethiazide. |
| Nicergoline | Nicergoline may decrease the antihypertensive activities of Trichlormethiazide. |
| Methoxamine | Methoxamine may decrease the antihypertensive activities of Trichlormethiazide. |
| Trimipramine | Trimipramine may decrease the antihypertensive activities of Trichlormethiazide. |
| Risperidone | Risperidone may decrease the antihypertensive activities of Trichlormethiazide. |
| Phenmetrazine | Phenmetrazine may decrease the antihypertensive activities of Trichlormethiazide. |
| Trifluoperazine | Trifluoperazine may decrease the antihypertensive activities of Trichlormethiazide. |
| Pseudoephedrine | Pseudoephedrine may decrease the antihypertensive activities of Trichlormethiazide. |
| Benzphetamine | Benzphetamine may decrease the antihypertensive activities of Trichlormethiazide. |
| Diethylpropion | Diethylpropion may decrease the antihypertensive activities of Trichlormethiazide. |
| Naratriptan | Naratriptan may decrease the antihypertensive activities of Trichlormethiazide. |
| Frovatriptan | Frovatriptan may decrease the antihypertensive activities of Trichlormethiazide. |
| Methoxyflurane | Methoxyflurane may decrease the antihypertensive activities of Trichlormethiazide. |
| Ergoloid mesylate | Ergoloid mesylate may decrease the antihypertensive activities of Trichlormethiazide. |
| Dutasteride | Dutasteride may decrease the antihypertensive activities of Trichlormethiazide. |
| Propafenone | Propafenone may decrease the antihypertensive activities of Trichlormethiazide. |
| Pergolide | Pergolide may decrease the antihypertensive activities of Trichlormethiazide. |
| Finasteride | Finasteride may decrease the antihypertensive activities of Trichlormethiazide. |
| Ergometrine | Ergometrine may decrease the antihypertensive activities of Trichlormethiazide. |
| Lisdexamfetamine | Lisdexamfetamine may decrease the antihypertensive activities of Trichlormethiazide. |
| Mephentermine | Mephentermine may decrease the antihypertensive activities of Trichlormethiazide. |
| Yohimbine | Yohimbine may decrease the antihypertensive activities of Trichlormethiazide. |
| MMDA | MMDA may decrease the antihypertensive activities of Trichlormethiazide. |
| Midomafetamine | Midomafetamine may decrease the antihypertensive activities of Trichlormethiazide. |
| 2,5-Dimethoxy-4-ethylamphetamine | 2,5-Dimethoxy-4-ethylamphetamine may decrease the antihypertensive activities of Trichlormethiazide. |
| 4-Methoxyamphetamine | 4-Methoxyamphetamine may decrease the antihypertensive activities of Trichlormethiazide. |
| 4-Bromo-2,5-dimethoxyamphetamine | 4-Bromo-2,5-dimethoxyamphetamine may decrease the antihypertensive activities of Trichlormethiazide. |
| Tenamfetamine | Tenamfetamine may decrease the antihypertensive activities of Trichlormethiazide. |
| Chlorphentermine | Chlorphentermine may decrease the antihypertensive activities of Trichlormethiazide. |
| Dextroamphetamine | Dextroamphetamine may decrease the antihypertensive activities of Trichlormethiazide. |
| Phendimetrazine | Phendimetrazine may decrease the antihypertensive activities of Trichlormethiazide. |
| Periciazine | Periciazine may decrease the antihypertensive activities of Trichlormethiazide. |
| Acepromazine | Acepromazine may decrease the antihypertensive activities of Trichlormethiazide. |
| Thioproperazine | Thioproperazine may decrease the antihypertensive activities of Trichlormethiazide. |
| Zuclopenthixol | Zuclopenthixol may decrease the antihypertensive activities of Trichlormethiazide. |
| Epicaptopril | Epicaptopril may decrease the antihypertensive activities of Trichlormethiazide. |
| 1-benzylimidazole | 1-benzylimidazole may decrease the antihypertensive activities of Trichlormethiazide. |
| Lysergic acid diethylamide | Lysergic acid diethylamide may decrease the antihypertensive activities of Trichlormethiazide. |
| Amineptine | Amineptine may decrease the antihypertensive activities of Trichlormethiazide. |
| Dronedarone | Dronedarone may decrease the antihypertensive activities of Trichlormethiazide. |
| Flibanserin | Flibanserin may decrease the antihypertensive activities of Trichlormethiazide. |
| Iloperidone | Iloperidone may decrease the antihypertensive activities of Trichlormethiazide. |
| Amibegron | Amibegron may decrease the antihypertensive activities of Trichlormethiazide. |
| Naluzotan | Naluzotan may decrease the antihypertensive activities of Trichlormethiazide. |
| Cariprazine | Cariprazine may decrease the antihypertensive activities of Trichlormethiazide. |
| Mianserin | Mianserin may decrease the antihypertensive activities of Trichlormethiazide. |
| Nylidrin | Nylidrin may decrease the antihypertensive activities of Trichlormethiazide. |
| Solabegron | Solabegron may decrease the antihypertensive activities of Trichlormethiazide. |
| Asenapine | Asenapine may decrease the antihypertensive activities of Trichlormethiazide. |
| Esmirtazapine | Esmirtazapine may decrease the antihypertensive activities of Trichlormethiazide. |
| Vilazodone | Vilazodone may decrease the antihypertensive activities of Trichlormethiazide. |
| Nitrous oxide | Nitrous oxide may decrease the antihypertensive activities of Trichlormethiazide. |
| Xylometazoline | Xylometazoline may decrease the antihypertensive activities of Trichlormethiazide. |
| Isometheptene | Isometheptene may decrease the antihypertensive activities of Trichlormethiazide. |
| Naphazoline | Naphazoline may decrease the antihypertensive activities of Trichlormethiazide. |
| Tetryzoline | Tetryzoline may decrease the antihypertensive activities of Trichlormethiazide. |
| Cinitapride | Cinitapride may decrease the antihypertensive activities of Trichlormethiazide. |
| Lurasidone | Lurasidone may decrease the antihypertensive activities of Trichlormethiazide. |
| Tyramine | Tyramine may decrease the antihypertensive activities of Trichlormethiazide. |
| Adrafinil | Adrafinil may decrease the antihypertensive activities of Trichlormethiazide. |
| Ifenprodil | Ifenprodil may decrease the antihypertensive activities of Trichlormethiazide. |
| Etilefrine | Etilefrine may decrease the antihypertensive activities of Trichlormethiazide. |
| Butriptyline | Butriptyline may decrease the antihypertensive activities of Trichlormethiazide. |
| Cannabidiol | Cannabidiol may decrease the antihypertensive activities of Trichlormethiazide. |
| Brexpiprazole | Brexpiprazole may decrease the antihypertensive activities of Trichlormethiazide. |
| Cirazoline | Cirazoline may decrease the antihypertensive activities of Trichlormethiazide. |
| Synephrine | Synephrine may decrease the antihypertensive activities of Trichlormethiazide. |
| Tianeptine | Tianeptine may decrease the antihypertensive activities of Trichlormethiazide. |
| Oxaprotiline | Oxaprotiline may decrease the antihypertensive activities of Trichlormethiazide. |
| Iofetamine I-123 | Iofetamine I-123 may decrease the antihypertensive activities of Trichlormethiazide. |
| Dihydroergocornine | Dihydroergocornine may decrease the antihypertensive activities of Trichlormethiazide. |
| Amitraz | Amitraz may decrease the antihypertensive activities of Trichlormethiazide. |
| Medetomidine | Medetomidine may decrease the antihypertensive activities of Trichlormethiazide. |