A single oral dose of balsalazide disodium at 5 grams/kg or 4-aminobenzoyl-(beta)-alanine, a metabolite of balsalazide disodium, at 1 gram/kg was non-lethal in mice and rats. No symptoms of acute toxicity were seen at these doses.
Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK.
The chemical name is (E)-5-[-4-(2-carboxyethyl) aminocarbonyl phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt.
Balsalazide works by deliverying mesalazine to the large intestine to act directly on ulcerative colitis. Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Amlodipine | Balsalazide may decrease the antihypertensive activities of Amlodipine. |
| Phentermine | The risk or severity of hypertension can be increased when Phentermine is combined with Balsalazide. |
| Midodrine | The risk or severity of hypertension can be increased when Midodrine is combined with Balsalazide. |
| Eletriptan | The risk or severity of hypertension can be increased when Eletriptan is combined with Balsalazide. |
| Isoetharine | The risk or severity of hypertension can be increased when Isoetharine is combined with Balsalazide. |
| Ziprasidone | The risk or severity of hypertension can be increased when Ziprasidone is combined with Balsalazide. |
| Methysergide | The risk or severity of hypertension can be increased when Methysergide is combined with Balsalazide. |
| Cabergoline | The risk or severity of hypertension can be increased when Cabergoline is combined with Balsalazide. |
| Zolmitriptan | The risk or severity of hypertension can be increased when Zolmitriptan is combined with Balsalazide. |
| Dihydroergotamine | The risk or severity of hypertension can be increased when Dihydroergotamine is combined with Balsalazide. |
| Methylergometrine | The risk or severity of hypertension can be increased when Methylergometrine is combined with Balsalazide. |
| Norepinephrine | The risk or severity of hypertension can be increased when Norepinephrine is combined with Balsalazide. |
| Mirtazapine | The risk or severity of hypertension can be increased when Mirtazapine is combined with Balsalazide. |
| Phenylephrine | The risk or severity of hypertension can be increased when Phenylephrine is combined with Balsalazide. |
| Phenylpropanolamine | The risk or severity of hypertension can be increased when Phenylpropanolamine is combined with Balsalazide. |
| Promazine | The risk or severity of hypertension can be increased when Promazine is combined with Balsalazide. |
| Droperidol | The risk or severity of hypertension can be increased when Droperidol is combined with Balsalazide. |
| Doxapram | The risk or severity of hypertension can be increased when Doxapram is combined with Balsalazide. |
| Atropine | The risk or severity of hypertension can be increased when Atropine is combined with Balsalazide. |
| Lisuride | The risk or severity of hypertension can be increased when Lisuride is combined with Balsalazide. |
| Linezolid | The risk or severity of hypertension can be increased when Linezolid is combined with Balsalazide. |
| Metaraminol | The risk or severity of hypertension can be increased when Metaraminol is combined with Balsalazide. |
| Furazolidone | The risk or severity of hypertension can be increased when Furazolidone is combined with Balsalazide. |
| Epinephrine | The risk or severity of hypertension can be increased when Epinephrine is combined with Balsalazide. |
| Thioridazine | The risk or severity of hypertension can be increased when Thioridazine is combined with Balsalazide. |
| Ergotamine | The risk or severity of hypertension can be increased when Ergotamine is combined with Balsalazide. |
| Nicergoline | The risk or severity of hypertension can be increased when Nicergoline is combined with Balsalazide. |
| Sufentanil | The risk or severity of hypertension can be increased when Sufentanil is combined with Balsalazide. |
| Methoxamine | The risk or severity of hypertension can be increased when Methoxamine is combined with Balsalazide. |
| Risperidone | The risk or severity of hypertension can be increased when Risperidone is combined with Balsalazide. |
| Tranylcypromine | The risk or severity of hypertension can be increased when Tranylcypromine is combined with Balsalazide. |
| Isoflurane | The risk or severity of hypertension can be increased when Isoflurane is combined with Balsalazide. |
| Propiomazine | The risk or severity of hypertension can be increased when Propiomazine is combined with Balsalazide. |
| Alfentanil | The risk or severity of hypertension can be increased when Alfentanil is combined with Balsalazide. |
| Minaprine | The risk or severity of hypertension can be increased when Minaprine is combined with Balsalazide. |
| Orciprenaline | The risk or severity of hypertension can be increased when Orciprenaline is combined with Balsalazide. |
| Propofol | The risk or severity of hypertension can be increased when Propofol is combined with Balsalazide. |
| Phenmetrazine | The risk or severity of hypertension can be increased when Phenmetrazine is combined with Balsalazide. |
| Trifluoperazine | The risk or severity of hypertension can be increased when Trifluoperazine is combined with Balsalazide. |
| Pseudoephedrine | The risk or severity of hypertension can be increased when Pseudoephedrine is combined with Balsalazide. |
| Benzphetamine | The risk or severity of hypertension can be increased when Benzphetamine is combined with Balsalazide. |
| Ritodrine | The risk or severity of hypertension can be increased when Ritodrine is combined with Balsalazide. |
| Flupentixol | The risk or severity of hypertension can be increased when Flupentixol is combined with Balsalazide. |
| Remifentanil | The risk or severity of hypertension can be increased when Remifentanil is combined with Balsalazide. |
| Bitolterol | The risk or severity of hypertension can be increased when Bitolterol is combined with Balsalazide. |
| Oxymetazoline | The risk or severity of hypertension can be increased when Oxymetazoline is combined with Balsalazide. |
| Diethylpropion | The risk or severity of hypertension can be increased when Diethylpropion is combined with Balsalazide. |
| Salmeterol | The risk or severity of hypertension can be increased when Salmeterol is combined with Balsalazide. |
| Naratriptan | The risk or severity of hypertension can be increased when Naratriptan is combined with Balsalazide. |
| Formoterol | The risk or severity of hypertension can be increased when Formoterol is combined with Balsalazide. |
| Frovatriptan | The risk or severity of hypertension can be increased when Frovatriptan is combined with Balsalazide. |
| Methoxyflurane | The risk or severity of hypertension can be increased when Balsalazide is combined with Methoxyflurane. |
| Selegiline | The risk or severity of hypertension can be increased when Balsalazide is combined with Selegiline. |
| Ergoloid mesylate | The risk or severity of hypertension can be increased when Balsalazide is combined with Ergoloid mesylate. |
| Isoprenaline | The risk or severity of hypertension can be increased when Balsalazide is combined with Isoprenaline. |
| Arbutamine | The risk or severity of hypertension can be increased when Balsalazide is combined with Arbutamine. |
| Dutasteride | The risk or severity of hypertension can be increased when Balsalazide is combined with Dutasteride. |
| Halothane | The risk or severity of hypertension can be increased when Balsalazide is combined with Halothane. |
| Moclobemide | The risk or severity of hypertension can be increased when Balsalazide is combined with Moclobemide. |
| Pergolide | The risk or severity of hypertension can be increased when Balsalazide is combined with Pergolide. |
| Desflurane | The risk or severity of hypertension can be increased when Balsalazide is combined with Desflurane. |
| Finasteride | The risk or severity of hypertension can be increased when Balsalazide is combined with Finasteride. |
| Aripiprazole | The risk or severity of hypertension can be increased when Balsalazide is combined with Aripiprazole. |
| Isocarboxazid | The risk or severity of hypertension can be increased when Balsalazide is combined with Isocarboxazid. |
| Ergometrine | The risk or severity of hypertension can be increased when Balsalazide is combined with Ergometrine. |
| Lisdexamfetamine | The risk or severity of hypertension can be increased when Balsalazide is combined with Lisdexamfetamine. |
| Fenoterol | The risk or severity of hypertension can be increased when Balsalazide is combined with Fenoterol. |
| Pirbuterol | The risk or severity of hypertension can be increased when Balsalazide is combined with Pirbuterol. |
| Ephedra sinica root | The risk or severity of hypertension can be increased when Balsalazide is combined with Ephedra sinica root. |
| Ephedrine | The risk or severity of hypertension can be increased when Balsalazide is combined with Ephedrine. |
| Mephentermine | The risk or severity of hypertension can be increased when Balsalazide is combined with Mephentermine. |
| Procaterol | The risk or severity of hypertension can be increased when Balsalazide is combined with Procaterol. |
| Yohimbine | The risk or severity of hypertension can be increased when Balsalazide is combined with Yohimbine. |
| Methotrimeprazine | The risk or severity of hypertension can be increased when Balsalazide is combined with Methotrimeprazine. |
| Clenbuterol | The risk or severity of hypertension can be increased when Balsalazide is combined with Clenbuterol. |
| Bambuterol | The risk or severity of hypertension can be increased when Balsalazide is combined with Bambuterol. |
| MMDA | The risk or severity of hypertension can be increased when Balsalazide is combined with MMDA. |
| Midomafetamine | The risk or severity of hypertension can be increased when Balsalazide is combined with Midomafetamine. |
| 2,5-Dimethoxy-4-ethylamphetamine | The risk or severity of hypertension can be increased when Balsalazide is combined with 2,5-Dimethoxy-4-ethylamphetamine. |
| 4-Methoxyamphetamine | The risk or severity of hypertension can be increased when Balsalazide is combined with 4-Methoxyamphetamine. |
| 4-Bromo-2,5-dimethoxyamphetamine | The risk or severity of hypertension can be increased when Balsalazide is combined with 4-Bromo-2,5-dimethoxyamphetamine. |
| Tenamfetamine | The risk or severity of hypertension can be increased when Balsalazide is combined with Tenamfetamine. |
| Chlorphentermine | The risk or severity of hypertension can be increased when Balsalazide is combined with Chlorphentermine. |
| Dextroamphetamine | The risk or severity of hypertension can be increased when Balsalazide is combined with Dextroamphetamine. |
| Phendimetrazine | The risk or severity of hypertension can be increased when Balsalazide is combined with Phendimetrazine. |
| Solifenacin | The risk or severity of hypertension can be increased when Balsalazide is combined with Solifenacin. |
| Periciazine | The risk or severity of hypertension can be increased when Balsalazide is combined with Periciazine. |
| Acepromazine | The risk or severity of hypertension can be increased when Balsalazide is combined with Acepromazine. |
| Thioproperazine | The risk or severity of hypertension can be increased when Balsalazide is combined with Thioproperazine. |
| Zuclopenthixol | The risk or severity of hypertension can be increased when Balsalazide is combined with Zuclopenthixol. |
| Epicaptopril | The risk or severity of hypertension can be increased when Balsalazide is combined with Epicaptopril. |
| Clorgiline | The risk or severity of hypertension can be increased when Balsalazide is combined with Clorgiline. |
| 1-benzylimidazole | The risk or severity of hypertension can be increased when Balsalazide is combined with 1-benzylimidazole. |
| Iproniazid | The risk or severity of hypertension can be increased when Balsalazide is combined with Iproniazid. |
| Nialamide | The risk or severity of hypertension can be increased when Balsalazide is combined with Nialamide. |
| Lysergic acid diethylamide | The risk or severity of hypertension can be increased when Balsalazide is combined with Lysergic acid diethylamide. |
| Dronedarone | The risk or severity of hypertension can be increased when Balsalazide is combined with Dronedarone. |
| Flibanserin | The risk or severity of hypertension can be increased when Balsalazide is combined with Flibanserin. |
| Iloperidone | The risk or severity of hypertension can be increased when Balsalazide is combined with Iloperidone. |
| Indacaterol | The risk or severity of hypertension can be increased when Balsalazide is combined with Indacaterol. |