Patients experiencing an overdose have presented with metabolic acidosis, hyperlactatemia, anxiety, palpitations, chest pain, sinus tachycardia, ST depression, hypokalemia, hypophosphatemia.A190450 Though patients may also present with seizures, angina, hypertension or hypotension, arrhythmia, headache, tremor, muscle cramps, dry mouth, nausea, dizziness, fatigue, malaise, insomnia, and hyperglycemia.L11548 Patients should be given symptomatic and supportive treatment which may include intravenous fluids, potassium supplementation, a cardioselective beta-blocker, and cardiac monitoring.A190450,L11548
Data regarding the LD50 of salmeterol is not readily available.L11569
Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.L11545,L11548,L11551,L11554,L11557 It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol.A190459 Salmeterol was first described in the literature in 1988.A190477 Salmeterol's structure is similar to salbutamol's with an aralkyloxy-alkyl substitution on the amine.A183737
Salmeterol was granted FDA approval on 4 February 1994.L11542
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Loxapine | The therapeutic efficacy of Salmeterol can be decreased when used in combination with Loxapine. |
| Valsartan | Salmeterol may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Salmeterol may decrease the antihypertensive activities of Ramipril. |
| Remikiren | Salmeterol may decrease the antihypertensive activities of Remikiren. |
| Olmesartan | Salmeterol may decrease the antihypertensive activities of Olmesartan. |
| Nitroprusside | Salmeterol may decrease the antihypertensive activities of Nitroprusside. |
| Minoxidil | Salmeterol may decrease the antihypertensive activities of Minoxidil. |
| Fosinopril | Salmeterol may decrease the antihypertensive activities of Fosinopril. |
| Trandolapril | Salmeterol may decrease the antihypertensive activities of Trandolapril. |
| Benazepril | Salmeterol may decrease the antihypertensive activities of Benazepril. |
| Candoxatril | Salmeterol may decrease the antihypertensive activities of Candoxatril. |
| Mecamylamine | Salmeterol may decrease the antihypertensive activities of Mecamylamine. |
| Lisinopril | Salmeterol may decrease the antihypertensive activities of Lisinopril. |
| Nitroglycerin | Salmeterol may decrease the antihypertensive activities of Nitroglycerin. |
| Metyrosine | Salmeterol may decrease the antihypertensive activities of Metyrosine. |
| Cryptenamine | Salmeterol may decrease the antihypertensive activities of Cryptenamine. |
| Perindopril | Salmeterol may decrease the antihypertensive activities of Perindopril. |
| Candesartan cilexetil | Salmeterol may decrease the antihypertensive activities of Candesartan cilexetil. |
| Fenoldopam | Salmeterol may decrease the antihypertensive activities of Fenoldopam. |
| Quinapril | Salmeterol may decrease the antihypertensive activities of Quinapril. |
| Telmisartan | Salmeterol may decrease the antihypertensive activities of Telmisartan. |
| Deserpidine | Salmeterol may decrease the antihypertensive activities of Deserpidine. |
| Pentolinium | Salmeterol may decrease the antihypertensive activities of Pentolinium. |
| Trimethaphan | Salmeterol may decrease the antihypertensive activities of Trimethaphan. |
| Diazoxide | Salmeterol may decrease the antihypertensive activities of Diazoxide. |
| Epoprostenol | Salmeterol may decrease the antihypertensive activities of Epoprostenol. |
| Cilazapril | Salmeterol may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Salmeterol may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Salmeterol may decrease the antihypertensive activities of Spirapril. |
| Tienilic acid | Salmeterol may decrease the antihypertensive activities of Tienilic acid. |
| Debrisoquine | Salmeterol may decrease the antihypertensive activities of Debrisoquine. |
| Diethylnorspermine | Salmeterol may decrease the antihypertensive activities of Diethylnorspermine. |
| Temocapril | Salmeterol may decrease the antihypertensive activities of Temocapril. |
| Hexamethonium | Salmeterol may decrease the antihypertensive activities of Hexamethonium. |
| Nicorandil | Salmeterol may decrease the antihypertensive activities of Nicorandil. |
| Rauwolfia serpentina root | Salmeterol may decrease the antihypertensive activities of Rauwolfia serpentina root. |
| Enalaprilat | Salmeterol may decrease the antihypertensive activities of Enalaprilat. |
| Angiotensin 1-7 | Salmeterol may decrease the antihypertensive activities of Angiotensin 1-7. |
| Imidapril | Salmeterol may decrease the antihypertensive activities of Imidapril. |
| BQ-123 | Salmeterol may decrease the antihypertensive activities of BQ-123. |
| Dihydralazine | Salmeterol may decrease the antihypertensive activities of Dihydralazine. |
| Zofenopril | Salmeterol may decrease the antihypertensive activities of Zofenopril. |
| Guanoxan | Salmeterol may decrease the antihypertensive activities of Guanoxan. |
| Delapril | Salmeterol may decrease the antihypertensive activities of Delapril. |
| Vincamine | Salmeterol may decrease the antihypertensive activities of Vincamine. |
| Linsidomine | Salmeterol may decrease the antihypertensive activities of Linsidomine. |
| Guanoxabenz | Salmeterol may decrease the antihypertensive activities of Guanoxabenz. |
| Tolonidine | Salmeterol may decrease the antihypertensive activities of Tolonidine. |
| Endralazine | Salmeterol may decrease the antihypertensive activities of Endralazine. |
| Cadralazine | Salmeterol may decrease the antihypertensive activities of Cadralazine. |
| Bietaserpine | Salmeterol may decrease the antihypertensive activities of Bietaserpine. |
| Guanazodine | Salmeterol may decrease the antihypertensive activities of Guanazodine. |
| Methoserpidine | Salmeterol may decrease the antihypertensive activities of Methoserpidine. |
| Guanoclor | Salmeterol may decrease the antihypertensive activities of Guanoclor. |
| Muzolimine | Salmeterol may decrease the antihypertensive activities of Muzolimine. |
| Xipamide | Salmeterol may decrease the antihypertensive activities of Xipamide. |
| Candesartan | Salmeterol may decrease the antihypertensive activities of Candesartan. |
| Tocopherylquinone | Salmeterol may decrease the antihypertensive activities of Tocopherylquinone. |
| Benazeprilat | Salmeterol may decrease the antihypertensive activities of Benazeprilat. |
| Fosinoprilat | Salmeterol may decrease the antihypertensive activities of Fosinoprilat. |
| Ramiprilat | Salmeterol may decrease the antihypertensive activities of Ramiprilat. |
| Perindoprilat | Salmeterol may decrease the antihypertensive activities of Perindoprilat. |
| Quinaprilat | Salmeterol may decrease the antihypertensive activities of Quinaprilat. |
| Bosentan | Salmeterol may decrease the antihypertensive activities of Bosentan. |
| Hydralazine | Salmeterol may decrease the antihypertensive activities of Hydralazine. |
| Sitaxentan | Salmeterol may decrease the antihypertensive activities of Sitaxentan. |
| Pinacidil | Salmeterol may decrease the antihypertensive activities of Pinacidil. |
| Macitentan | Salmeterol may decrease the antihypertensive activities of Macitentan. |
| Aliskiren | Salmeterol may decrease the antihypertensive activities of Aliskiren. |
| Manidipine | Salmeterol may decrease the antihypertensive activities of Manidipine. |
| Naftopidil | Salmeterol may decrease the antihypertensive activities of Naftopidil. |
| Dexniguldipine | Salmeterol may decrease the antihypertensive activities of Dexniguldipine. |
| Amlodipine | Salmeterol may decrease the antihypertensive activities of Amlodipine. |
| Azilsartan medoxomil | Salmeterol may decrease the antihypertensive activities of Azilsartan medoxomil. |
| Desmopressin | The risk or severity of hypertension can be increased when Desmopressin is combined with Salmeterol. |
| Icosapent | The risk or severity of hypertension can be increased when Icosapent is combined with Salmeterol. |
| Amphetamine | The risk or severity of hypertension can be increased when Amphetamine is combined with Salmeterol. |
| Midodrine | The risk or severity of hypertension can be increased when Midodrine is combined with Salmeterol. |
| Bethanidine | Salmeterol may decrease the antihypertensive activities of Bethanidine. |
| Mesalazine | The risk or severity of hypertension can be increased when Mesalazine is combined with Salmeterol. |
| Etomidate | The risk or severity of hypertension can be increased when Etomidate is combined with Salmeterol. |
| Zolmitriptan | The risk or severity of hypertension can be increased when Zolmitriptan is combined with Salmeterol. |
| Indomethacin | The risk or severity of hypertension can be increased when Indomethacin is combined with Salmeterol. |
| Phenylephrine | The risk or severity of hypertension can be increased when Phenylephrine is combined with Salmeterol. |
| Methylphenidate | The risk or severity of hypertension can be increased when Methylphenidate is combined with Salmeterol. |
| Nabumetone | The risk or severity of hypertension can be increased when Nabumetone is combined with Salmeterol. |
| Tenoxicam | The risk or severity of hypertension can be increased when Tenoxicam is combined with Salmeterol. |
| Tolmetin | The risk or severity of hypertension can be increased when Tolmetin is combined with Salmeterol. |
| Doxapram | The risk or severity of hypertension can be increased when Doxapram is combined with Salmeterol. |
| Fenoprofen | The risk or severity of hypertension can be increased when Fenoprofen is combined with Salmeterol. |
| Sulindac | The risk or severity of hypertension can be increased when Sulindac is combined with Salmeterol. |
| Metaraminol | The risk or severity of hypertension can be increased when Metaraminol is combined with Salmeterol. |
| Guanabenz | Salmeterol may decrease the antihypertensive activities of Guanabenz. |
| Dexmedetomidine | The risk or severity of hypertension can be increased when Dexmedetomidine is combined with Salmeterol. |
| Sumatriptan | The risk or severity of hypertension can be increased when Sumatriptan is combined with Salmeterol. |
| Flurbiprofen | The risk or severity of hypertension can be increased when Flurbiprofen is combined with Salmeterol. |
| Methoxamine | The risk or severity of hypertension can be increased when Methoxamine is combined with Salmeterol. |
| Etodolac | The risk or severity of hypertension can be increased when Etodolac is combined with Salmeterol. |
| Sulfasalazine | The risk or severity of hypertension can be increased when Sulfasalazine is combined with Salmeterol. |
| Carprofen | The risk or severity of hypertension can be increased when Carprofen is combined with Salmeterol. |