Oral LD50 is 560 ± 62.5 mg/kg and 644 ± 48 mg/kg in mouse and rat, respectively. Symptoms of overdose may include emesis, muscle tremors, decreased food intake and death associated with aspiration of oral-gastric contents into the respiratory system.
A phenothiazine antipsychotic with effects similar to chlorpromazine.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Ivabradine | Ivabradine may increase the QTc-prolonging activities of Mesoridazine. |
| Buprenorphine | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Mesoridazine. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Mesoridazine. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Mesoridazine. |
| Hydrocodone | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Magnesium sulfate | The therapeutic efficacy of Mesoridazine can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Mesoridazine. |
| Mirtazapine | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Mesoridazine. |
| Orphenadrine | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Mesoridazine. |
| Rotigotine | Mesoridazine may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Mesoridazine. |
| Sodium oxybate | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Suvorexant | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Mesoridazine. |
| Thalidomide | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Amisulpride | Mesoridazine may increase the antipsychotic activities of Amisulpride. |
| Methylphenidate | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Methylphenidate. |
| Dexmethylphenidate | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Dexmethylphenidate. |
| Metoclopramide | The risk or severity of adverse effects can be increased when Metoclopramide is combined with Mesoridazine. |
| Quinagolide | The therapeutic efficacy of Quinagolide can be decreased when used in combination with Mesoridazine. |
| Sulpiride | Mesoridazine may increase the antipsychotic activities of Sulpiride. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Mesoridazine. |
| Lithium citrate | Lithium citrate may increase the neurotoxic activities of Mesoridazine. |
| Lithium hydroxide | Lithium hydroxide may increase the neurotoxic activities of Mesoridazine. |
| Mequitazine | Mesoridazine may increase the arrhythmogenic activities of Mequitazine. |
| Thiopental | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Thiopental. |
| Dicoumarol | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Dicoumarol. |
| Phenindione | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Phenindione. |
| Warfarin | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Warfarin. |
| Phenprocoumon | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Phenprocoumon. |
| Acenocoumarol | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Acenocoumarol. |
| 4-hydroxycoumarin | The risk or severity of adverse effects can be increased when Mesoridazine is combined with 4-hydroxycoumarin. |
| Coumarin | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Coumarin. |
| (R)-warfarin | The risk or severity of adverse effects can be increased when Mesoridazine is combined with (R)-warfarin. |
| Ethyl biscoumacetate | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Ethyl biscoumacetate. |
| Fluindione | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Fluindione. |
| Clorindione | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Clorindione. |
| Diphenadione | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Diphenadione. |
| Tioclomarol | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Tioclomarol. |
| (S)-Warfarin | The risk or severity of adverse effects can be increased when Mesoridazine is combined with (S)-Warfarin. |
| Metyrosine | The risk or severity of extrapyramidal symptoms and CNS depression can be increased when Metyrosine is combined with Mesoridazine. |
| Mirabegron | The serum concentration of Mesoridazine can be increased when it is combined with Mirabegron. |
| Ethanol | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Mesoridazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Mesoridazine. |
| Zimelidine | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Zimelidine. |
| Dapoxetine | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Dapoxetine. |
| Seproxetine | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Seproxetine. |
| Sertraline | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Sertraline. |
| Sibutramine | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Sibutramine. |
| Nefazodone | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Nefazodone. |
| Milnacipran | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Milnacipran. |
| Desvenlafaxine | The serum concentration of Mesoridazine can be increased when it is combined with Desvenlafaxine. |
| Levomilnacipran | The risk or severity of adverse effects can be increased when Levomilnacipran is combined with Mesoridazine. |
| Indalpine | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Indalpine. |
| Alaproclate | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Alaproclate. |
| Esmolol | The serum concentration of Esmolol can be increased when it is combined with Mesoridazine. |
| Betaxolol | The serum concentration of Betaxolol can be increased when it is combined with Mesoridazine. |
| Atenolol | The serum concentration of Atenolol can be increased when it is combined with Mesoridazine. |
| Timolol | The serum concentration of Timolol can be increased when it is combined with Mesoridazine. |
| Propranolol | The serum concentration of Propranolol can be increased when it is combined with Mesoridazine. |
| Labetalol | The serum concentration of Labetalol can be increased when it is combined with Mesoridazine. |
| Bisoprolol | The serum concentration of Bisoprolol can be increased when it is combined with Mesoridazine. |
| Alprenolol | The serum concentration of Alprenolol can be increased when it is combined with Mesoridazine. |
| Pindolol | The serum concentration of Pindolol can be increased when it is combined with Mesoridazine. |
| Carvedilol | The serum concentration of Carvedilol can be increased when it is combined with Mesoridazine. |
| Acebutolol | The serum concentration of Acebutolol can be increased when it is combined with Mesoridazine. |
| Nadolol | The serum concentration of Nadolol can be increased when it is combined with Mesoridazine. |
| Bevantolol | The serum concentration of Bevantolol can be increased when it is combined with Mesoridazine. |
| Practolol | The serum concentration of Practolol can be increased when it is combined with Mesoridazine. |
| Penbutolol | The serum concentration of Penbutolol can be increased when it is combined with Mesoridazine. |
| Oxprenolol | The serum concentration of Oxprenolol can be increased when it is combined with Mesoridazine. |
| Dexpropranolol | The serum concentration of Dexpropranolol can be increased when it is combined with Mesoridazine. |
| Celiprolol | The serum concentration of Celiprolol can be increased when it is combined with Mesoridazine. |
| Nebivolol | The serum concentration of Nebivolol can be increased when it is combined with Mesoridazine. |
| Bufuralol | The serum concentration of Bufuralol can be increased when it is combined with Mesoridazine. |
| Bopindolol | The serum concentration of Bopindolol can be increased when it is combined with Mesoridazine. |
| Bupranolol | The serum concentration of Bupranolol can be increased when it is combined with Mesoridazine. |
| Indenolol | The serum concentration of Indenolol can be increased when it is combined with Mesoridazine. |
| Arotinolol | The serum concentration of Arotinolol can be increased when it is combined with Mesoridazine. |
| Levobetaxolol | The serum concentration of Levobetaxolol can be increased when it is combined with Mesoridazine. |
| Talinolol | The serum concentration of Talinolol can be increased when it is combined with Mesoridazine. |
| Anisodamine | The serum concentration of Anisodamine can be increased when it is combined with Mesoridazine. |
| Bucindolol | The serum concentration of Bucindolol can be increased when it is combined with Mesoridazine. |
| Esatenolol | The serum concentration of Esatenolol can be increased when it is combined with Mesoridazine. |
| Cloranolol | The serum concentration of Cloranolol can be increased when it is combined with Mesoridazine. |
| Mepindolol | The serum concentration of Mepindolol can be increased when it is combined with Mesoridazine. |
| Epanolol | The serum concentration of Epanolol can be increased when it is combined with Mesoridazine. |
| Tertatolol | The serum concentration of Tertatolol can be increased when it is combined with Mesoridazine. |
| Landiolol | The serum concentration of Landiolol can be increased when it is combined with Mesoridazine. |
| Morphine | The risk or severity of hypotension and CNS depression can be increased when Mesoridazine is combined with Morphine. |
| Codeine | The risk or severity of hypotension and CNS depression can be increased when Mesoridazine is combined with Codeine. |
| Hydromorphone | The risk or severity of hypotension and CNS depression can be increased when Mesoridazine is combined with Hydromorphone. |
| Oxycodone | The risk or severity of hypotension and CNS depression can be increased when Mesoridazine is combined with Oxycodone. |