A biguanide hypoglycemic agent with actions and uses similar to those of metformin. Although it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often fatal, it is still available in some countries. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Pegvisomant | The risk or severity of hypoglycemia can be increased when Pegvisomant is combined with Phenformin. |
| Mirabegron | The serum concentration of Phenformin can be increased when it is combined with Mirabegron. |
| Lipoic acid | The risk or severity of hypoglycemia can be increased when Lipoic acid is combined with Phenformin. |
| Moxifloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Moxifloxacin. |
| Grepafloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Grepafloxacin. |
| Enoxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Enoxacin. |
| Pefloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Pefloxacin. |
| Ciprofloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Ciprofloxacin. |
| Trovafloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Trovafloxacin. |
| Nalidixic acid | The therapeutic efficacy of Phenformin can be increased when used in combination with Nalidixic acid. |
| Rosoxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Rosoxacin. |
| Cinoxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Cinoxacin. |
| Lomefloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Lomefloxacin. |
| Gatifloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Gatifloxacin. |
| Norfloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Norfloxacin. |
| Levofloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Levofloxacin. |
| Gemifloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Gemifloxacin. |
| Ofloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Ofloxacin. |
| Sparfloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Sparfloxacin. |
| Temafloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Temafloxacin. |
| Fleroxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Fleroxacin. |
| Technetium Tc-99m ciprofloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Technetium Tc-99m ciprofloxacin. |
| Garenoxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Garenoxacin. |
| Nemonoxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Nemonoxacin. |
| Flumequine | The therapeutic efficacy of Phenformin can be increased when used in combination with Flumequine. |
| Enrofloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Enrofloxacin. |
| Orbifloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Orbifloxacin. |
| Sarafloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Sarafloxacin. |
| Difloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Difloxacin. |
| Pazufloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Pazufloxacin. |
| Prulifloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Prulifloxacin. |
| Delafloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Delafloxacin. |
| Sitafloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Sitafloxacin. |
| Oxolinic acid | The therapeutic efficacy of Phenformin can be increased when used in combination with Oxolinic acid. |
| Rufloxacin | The therapeutic efficacy of Phenformin can be increased when used in combination with Rufloxacin. |
| Pipemidic acid | The therapeutic efficacy of Phenformin can be increased when used in combination with Pipemidic acid. |
| Methyclothiazide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Methyclothiazide. |
| Chlorthalidone | The therapeutic efficacy of Phenformin can be decreased when used in combination with Chlorthalidone. |
| Bendroflumethiazide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Bendroflumethiazide. |
| Metolazone | The therapeutic efficacy of Phenformin can be decreased when used in combination with Metolazone. |
| Benzthiazide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Benzthiazide. |
| Hydroflumethiazide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Hydroflumethiazide. |
| Indapamide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Indapamide. |
| Chlorothiazide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Chlorothiazide. |
| Hydrochlorothiazide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Hydrochlorothiazide. |
| Trichlormethiazide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Trichlormethiazide. |
| Polythiazide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Polythiazide. |
| Quinethazone | The therapeutic efficacy of Phenformin can be decreased when used in combination with Quinethazone. |
| Cyclopenthiazide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Cyclopenthiazide. |
| Epitizide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Epitizide. |
| Amineptine | Amineptine may decrease the hypoglycemic activities of Phenformin. |
| Dimetacrine | Dimetacrine may decrease the hypoglycemic activities of Phenformin. |
| Butriptyline | Butriptyline may decrease the hypoglycemic activities of Phenformin. |
| Tianeptine | Tianeptine may decrease the hypoglycemic activities of Phenformin. |
| Oxaprotiline | Oxaprotiline may decrease the hypoglycemic activities of Phenformin. |
| Amitriptylinoxide | Amitriptylinoxide may decrease the hypoglycemic activities of Phenformin. |
| Dibenzepin | Dibenzepin may decrease the hypoglycemic activities of Phenformin. |
| Quinupramine | Quinupramine may decrease the hypoglycemic activities of Phenformin. |
| Melitracen | Melitracen may decrease the hypoglycemic activities of Phenformin. |
| Lofepramine | Lofepramine may decrease the hypoglycemic activities of Phenformin. |
| Iprindole | Iprindole may decrease the hypoglycemic activities of Phenformin. |
| Imipramine oxide | Imipramine oxide may decrease the hypoglycemic activities of Phenformin. |
| Protriptyline | Protriptyline may decrease the hypoglycemic activities of Phenformin. |
| Opipramol | Opipramol may decrease the hypoglycemic activities of Phenformin. |
| Doxepin | Doxepin may decrease the hypoglycemic activities of Phenformin. |
| Dapagliflozin | Dapagliflozin may increase the hypoglycemic activities of Phenformin. |
| Canagliflozin | Canagliflozin may increase the hypoglycemic activities of Phenformin. |
| Leuprolide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Leuprolide. |
| Goserelin | The therapeutic efficacy of Phenformin can be decreased when used in combination with Goserelin. |
| Indinavir | The therapeutic efficacy of Phenformin can be decreased when used in combination with Indinavir. |
| Ziprasidone | The therapeutic efficacy of Phenformin can be decreased when used in combination with Ziprasidone. |
| Etonogestrel | The therapeutic efficacy of Phenformin can be decreased when used in combination with Etonogestrel. |
| Desogestrel | The therapeutic efficacy of Phenformin can be decreased when used in combination with Desogestrel. |
| Olanzapine | The therapeutic efficacy of Phenformin can be decreased when used in combination with Olanzapine. |
| Megestrol acetate | The therapeutic efficacy of Phenformin can be decreased when used in combination with Megestrol acetate. |
| Levonorgestrel | The therapeutic efficacy of Phenformin can be decreased when used in combination with Levonorgestrel. |
| Progesterone | The therapeutic efficacy of Phenformin can be decreased when used in combination with Progesterone. |
| Piperazine | The therapeutic efficacy of Phenformin can be decreased when used in combination with Piperazine. |
| Medroxyprogesterone acetate | The therapeutic efficacy of Phenformin can be decreased when used in combination with Medroxyprogesterone acetate. |
| Niacin | The therapeutic efficacy of Phenformin can be decreased when used in combination with Niacin. |
| Norethisterone | The therapeutic efficacy of Phenformin can be decreased when used in combination with Norethisterone. |
| Risperidone | The therapeutic efficacy of Phenformin can be decreased when used in combination with Risperidone. |
| Pentamidine | The therapeutic efficacy of Phenformin can be decreased when used in combination with Pentamidine. |
| Ethynodiol diacetate | The therapeutic efficacy of Phenformin can be decreased when used in combination with Ethynodiol diacetate. |
| Pseudoephedrine | The therapeutic efficacy of Phenformin can be decreased when used in combination with Pseudoephedrine. |
| Tacrolimus | The therapeutic efficacy of Phenformin can be decreased when used in combination with Tacrolimus. |
| Sirolimus | The therapeutic efficacy of Phenformin can be decreased when used in combination with Sirolimus. |
| Etacrynic acid | The therapeutic efficacy of Phenformin can be decreased when used in combination with Etacrynic acid. |
| Norgestimate | The therapeutic efficacy of Phenformin can be decreased when used in combination with Norgestimate. |
| Ethinylestradiol | The therapeutic efficacy of Phenformin can be decreased when used in combination with Ethinylestradiol. |
| Atazanavir | The therapeutic efficacy of Phenformin can be decreased when used in combination with Atazanavir. |
| Arsenic trioxide | The therapeutic efficacy of Phenformin can be decreased when used in combination with Arsenic trioxide. |
| Quetiapine | The therapeutic efficacy of Phenformin can be decreased when used in combination with Quetiapine. |
| Saquinavir | The therapeutic efficacy of Phenformin can be decreased when used in combination with Saquinavir. |
| Aripiprazole | The therapeutic efficacy of Phenformin can be decreased when used in combination with Aripiprazole. |
| Paliperidone | The therapeutic efficacy of Phenformin can be decreased when used in combination with Paliperidone. |
| Fosamprenavir | The therapeutic efficacy of Phenformin can be decreased when used in combination with Fosamprenavir. |
| St. John's Wort | The therapeutic efficacy of Phenformin can be decreased when used in combination with St. John's Wort. |
| Mestranol | The therapeutic efficacy of Phenformin can be decreased when used in combination with Mestranol. |
| Ephedra sinica root | The therapeutic efficacy of Phenformin can be decreased when used in combination with Ephedra sinica root. |