There are no reported overdoses with tinidazole in humans. In acute studies with mice and rats, the LD 50 for mice was generally > 3,600 mg/kg for oral administration and was > 2,300 mg/kg for intraperitoneal administration. In rats, the LD 50 was > 2,000 mg/kg for both oral and intraperitoneal administration.
A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Troglitazone | Troglitazone may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Erythromycin | The serum concentration of Tinidazole can be increased when it is combined with Erythromycin. |
| Reserpine | Reserpine may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Progesterone | Progesterone may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Chlorpromazine | Chlorpromazine may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Cimetidine | Cimetidine may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Bosentan | Bosentan may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Tamoxifen | Tamoxifen may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Ethinylestradiol | Ethinylestradiol may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Glyburide | Glyburide may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Ursodeoxycholic acid | Ursodeoxycholic acid may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Cholic Acid | Cholic Acid may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Fusidic acid | Fusidic acid may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Simeprevir | Simeprevir may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Lenvatinib | Lenvatinib may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Valinomycin | Valinomycin may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Celecoxib | Celecoxib may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Nifedipine | Tinidazole may decrease the excretion rate of Nifedipine which could result in a higher serum level. |
| Cyclosporine | Cyclosporine may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Olmesartan | Olmesartan may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Pralsetinib | Pralsetinib may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Disulfiram | The risk or severity of adverse effects can be increased when Tinidazole is combined with Disulfiram. |
| Picosulfuric acid | The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Tinidazole. |
| Ethanol | The risk or severity of adverse effects can be increased when Tinidazole is combined with Ethanol. |
| BCG vaccine | The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Tinidazole. |
| Typhoid vaccine | The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Tinidazole. |
| Pitolisant | The serum concentration of Tinidazole can be decreased when it is combined with Pitolisant. |
| Deoxycholic acid | Deoxycholic acid may increase the excretion rate of Tinidazole which could result in a lower serum level and potentially a reduction in efficacy. |
| Taurocholic acid | Taurocholic acid may increase the excretion rate of Tinidazole which could result in a lower serum level and potentially a reduction in efficacy. |
| Dexamethasone acetate | Dexamethasone acetate may increase the excretion rate of Tinidazole which could result in a lower serum level and potentially a reduction in efficacy. |
| Pravastatin | Pravastatin may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Glimepiride | Glimepiride may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Atenolol | Atenolol may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Atropine | Atropine may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Fluorescein | Fluorescein may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Telmisartan | Tinidazole may decrease the excretion rate of Telmisartan which could result in a higher serum level. |
| Dipyridamole | Tinidazole may decrease the excretion rate of Dipyridamole which could result in a higher serum level. |
| Ofloxacin | Tinidazole may decrease the excretion rate of Ofloxacin which could result in a higher serum level. |
| Prasterone sulfate | Tinidazole may decrease the excretion rate of Prasterone sulfate which could result in a higher serum level. |
| Indocyanine green acid form | Tinidazole may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Benzbromarone | Tinidazole may decrease the excretion rate of Benzbromarone which could result in a higher serum level. |
| Pilsicainide | Tinidazole may decrease the excretion rate of Pilsicainide which could result in a higher serum level. |
| Glycyrrhizic acid | Tinidazole may decrease the excretion rate of Glycyrrhizic acid which could result in a higher serum level. |
| Indomethacin | Indomethacin may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Diclofenac | Diclofenac may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Naproxen | Naproxen may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Cefaclor | Cefaclor may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Fluvoxamine | The metabolism of Tinidazole can be decreased when combined with Fluvoxamine. |
| Ranolazine | Ranolazine may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Isradipine | The metabolism of Tinidazole can be decreased when combined with Isradipine. |
| Rosiglitazone | Rosiglitazone may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Nitrofurantoin | Nitrofurantoin may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Sulfamethoxazole | Tinidazole may decrease the excretion rate of Sulfamethoxazole which could result in a higher serum level. |
| Fenofibrate | Tinidazole may decrease the excretion rate of Fenofibrate which could result in a higher serum level. |
| Glipizide | Tinidazole may decrease the excretion rate of Glipizide which could result in a higher serum level. |
| Ezetimibe | Tinidazole may decrease the excretion rate of Ezetimibe which could result in a higher serum level. |
| Glycochenodeoxycholic Acid | Tinidazole may decrease the excretion rate of Glycochenodeoxycholic Acid which could result in a higher serum level. |
| Diethylstilbestrol | Diethylstilbestrol may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Flucloxacillin | Flucloxacillin may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Cerivastatin | Cerivastatin may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Loratadine | Loratadine may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Imatinib | Imatinib may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Nicardipine | The metabolism of Tinidazole can be decreased when combined with Nicardipine. |
| Simvastatin | Simvastatin may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Mifepristone | Mifepristone may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Repaglinide | Tinidazole may decrease the excretion rate of Repaglinide which could result in a higher serum level. |
| Felodipine | Tinidazole may decrease the excretion rate of Felodipine which could result in a higher serum level. |
| Nitrendipine | Tinidazole may decrease the excretion rate of Nitrendipine which could result in a higher serum level. |
| Atorvastatin | Tinidazole may decrease the excretion rate of Atorvastatin which could result in a higher serum level. |
| Rosuvastatin | Tinidazole may decrease the excretion rate of Rosuvastatin which could result in a higher serum level. |
| Sulfinpyrazone | Tinidazole may decrease the excretion rate of Sulfinpyrazone which could result in a higher serum level. |
| Budesonide | Tinidazole may decrease the excretion rate of Budesonide which could result in a higher serum level. |
| Dihydroergocristine | Tinidazole may decrease the excretion rate of Dihydroergocristine which could result in a higher serum level. |
| Belantamab mafodotin | Tinidazole may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level. |
| Vinblastine | Vinblastine may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Digoxin | Tinidazole may decrease the excretion rate of Digoxin which could result in a higher serum level. |
| Paclitaxel | Paclitaxel may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Vincristine | Vincristine may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Astemizole | Astemizole may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Doxorubicin | Tinidazole may decrease the excretion rate of Doxorubicin which could result in a higher serum level. |
| Icosapent | Icosapent may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Cefotiam | Cefotiam may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Mesalazine | Mesalazine may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Cefmenoxime | Cefmenoxime may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Cefmetazole | Cefmetazole may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Pamidronic acid | Pamidronic acid may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Tenofovir disoproxil | Tenofovir disoproxil may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Cidofovir | Cidofovir may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Cefpiramide | Cefpiramide may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Ceftazidime | Ceftazidime may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Loracarbef | Loracarbef may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Cefalotin | Cefalotin may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Nabumetone | Nabumetone may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Ketorolac | Ketorolac may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Tenoxicam | Tenoxicam may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Cefotaxime | Cefotaxime may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Tolmetin | Tolmetin may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Foscarnet | Foscarnet may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Rofecoxib | Rofecoxib may decrease the excretion rate of Tinidazole which could result in a higher serum level. |
| Piroxicam | Piroxicam may decrease the excretion rate of Tinidazole which could result in a higher serum level. |