Peringatan Keamanan

Oral, rat LD50: 5628 mg/kg. Symptoms and effects of overdose include nausea, vomiting, CNS depression, acute respiratory failure or death and with chronic use, severe health problems, such as liver and brain damage.

Ethanol

DB00898

small molecule approved

Deskripsi

A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.

Struktur Molekul 2D

Berat 46.0684
Wujud liquid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Rapidly absorbed.

Metabolisme

Hepatic. Metabolized by cytochrome P450 enzyme CYP2E1.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1534 Data
Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Ethanol.
Deferasirox The serum concentration of Ethanol can be increased when it is combined with Deferasirox.
Peginterferon alfa-2b The serum concentration of Ethanol can be increased when it is combined with Peginterferon alfa-2b.
Leflunomide The serum concentration of Ethanol can be decreased when it is combined with Leflunomide.
Teriflunomide The serum concentration of Ethanol can be decreased when it is combined with Teriflunomide.
Metyrosine Ethanol may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Pramipexole Ethanol may increase the sedative activities of Pramipexole.
Ropinirole Ethanol may increase the sedative activities of Ropinirole.
Thalidomide The risk or severity of somnolence and peripheral neuropathy can be increased when Thalidomide is combined with Ethanol.
Eliglustat The metabolism of Eliglustat can be decreased when combined with Ethanol.
Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Ethanol.
Colchicine The metabolism of Colchicine can be decreased when combined with Ethanol.
Fentanyl Fentanyl may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Retapamulin The metabolism of Retapamulin can be decreased when combined with Ethanol.
Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Ethanol.
Vardenafil The metabolism of Vardenafil can be decreased when combined with Ethanol.
Lovastatin The metabolism of Lovastatin can be decreased when combined with Ethanol.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Ethanol.
Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Ethanol.
Memantine The risk or severity of adverse effects can be increased when Ethanol is combined with Memantine.
Ifosfamide The metabolism of Ifosfamide can be increased when combined with Ethanol.
Warfarin The serum concentration of Warfarin can be increased when it is combined with Ethanol.
Acenocoumarol The serum concentration of Acenocoumarol can be increased when it is combined with Ethanol.
(R)-warfarin The serum concentration of (R)-warfarin can be increased when it is combined with Ethanol.
R,S-Warfarin alcohol The serum concentration of R,S-Warfarin alcohol can be increased when it is combined with Ethanol.
S,R-Warfarin alcohol The serum concentration of S,R-Warfarin alcohol can be increased when it is combined with Ethanol.
(S)-Warfarin The serum concentration of (S)-Warfarin can be increased when it is combined with Ethanol.
Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Ethanol.
Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Ethanol.
Abiraterone The serum concentration of Ethanol can be increased when it is combined with Abiraterone.
Lithium citrate The risk or severity of adverse effects can be increased when Ethanol is combined with Lithium citrate.
Pimavanserin The metabolism of Pimavanserin can be increased when combined with Ethanol.
Botulinum toxin type B Botulinum toxin type B may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Botulinum toxin type A Botulinum toxin type A may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Tryptophan Tryptophan may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Fluvoxamine Fluvoxamine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Lorazepam Lorazepam may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Ethchlorvynol Ethchlorvynol may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Tramadol Tramadol may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Succinylcholine Succinylcholine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Reserpine Reserpine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Citalopram Citalopram may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Eletriptan Eletriptan may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Enflurane Enflurane may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Pregabalin Pregabalin may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Temazepam Temazepam may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Reboxetine Reboxetine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Butabarbital Butabarbital may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Butalbital Butalbital may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Ziprasidone Ziprasidone may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Methysergide Methysergide may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Cabergoline Cabergoline may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Phenytoin Phenytoin may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Clemastine Clemastine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Venlafaxine Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Etomidate Etomidate may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Morphine Morphine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Talbutal Talbutal may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Pentobarbital Pentobarbital may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Valproic acid Valproic acid may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Zolmitriptan Zolmitriptan may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Dihydroergotamine Dihydroergotamine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Amitriptyline Amitriptyline may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Tolcapone Tolcapone may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Hydromorphone Hydromorphone may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Olanzapine Olanzapine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Cetirizine Cetirizine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Protriptyline Protriptyline may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Trimethadione Trimethadione may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Ethanol.
Chlorzoxazone Chlorzoxazone may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Clozapine Clozapine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Meprobamate Meprobamate may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Thiethylperazine Thiethylperazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Palonosetron Palonosetron may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Sulpiride Sulpiride may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Carisoprodol Carisoprodol may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Eszopiclone Eszopiclone may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Alprazolam Alprazolam may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Dexbrompheniramine Dexbrompheniramine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Loxapine Loxapine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Remoxipride Remoxipride may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Metocurine iodide Metocurine iodide may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Secobarbital Secobarbital may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Promazine Promazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Methocarbamol Methocarbamol may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Zolpidem Zolpidem may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Triprolidine Triprolidine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Prochlorperazine Prochlorperazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Cyproheptadine Cyproheptadine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Meperidine Meperidine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Imipramine Imipramine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Metharbital Metharbital may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Quinine Quinine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Fluoxetine Fluoxetine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Methohexital Methohexital may increase the central nervous system depressant (CNS depressant) activities of Ethanol.

Target Protein

Gamma-aminobutyric acid receptor subunit alpha-1 GABRA1
Glutamate receptor ionotropic, NMDA 3A GRIN3A
Glycine receptor subunit alpha-1 GLRA1
Glycine receptor subunit alpha-2 GLRA2
Voltage-dependent L-type calcium channel subunit beta-1 CACNB1
5-hydroxytryptamine receptor 3A HTR3A
Gamma-aminobutyric acid receptor subunit alpha-2 GABRA2
Neuronal acetylcholine receptor subunit alpha-10 CHRNA10
Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C
Gamma-aminobutyric acid receptor subunit alpha-5 GABRA5
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4
Gamma-aminobutyric acid receptor subunit alpha-3 GABRA3
Glutamate receptor 1 GRIA1
Voltage-dependent calcium channel gamma-1 subunit CACNG1
Neuronal acetylcholine receptor subunit alpha-2 CHRNA2
Gamma-aminobutyric acid receptor subunit alpha-6 GABRA6
Glutamate receptor 2 GRIA2
Glutamate receptor 4 GRIA4
Glutamate receptor 3 GRIA3
Neuronal acetylcholine receptor subunit alpha-4 CHRNA4
Neuronal acetylcholine receptor subunit beta-2 CHRNB2
G protein-activated inward rectifier potassium channel 1 KCNJ3
G protein-activated inward rectifier potassium channel 2 KCNJ6
Vascular cell adhesion protein 1 VCAM1
Equilibrative nucleoside transporter 1 SLC29A1
G protein-activated inward rectifier potassium channel 4 KCNJ5
Neuronal acetylcholine receptor subunit alpha-7 CHRNA7
Neuronal acetylcholine receptor subunit alpha-9 CHRNA9
Gamma-aminobutyric acid receptor subunit beta-1 GABRB1
Gamma-aminobutyric acid receptor subunit beta-3 GABRB3
Gamma-aminobutyric acid receptor subunit beta-2 GABRB2
Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S
Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D
Neuronal acetylcholine receptor subunit beta-4 CHRNB4
Neuronal acetylcholine receptor subunit alpha-3 CHRNA3
Neuronal acetylcholine receptor subunit alpha-5 CHRNA5
Neuronal acetylcholine receptor subunit alpha-6 CHRNA6
Neuronal acetylcholine receptor subunit beta-3 CHRNB3
Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1
Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3
Gamma-aminobutyric acid receptor subunit epsilon GABRE
Gamma-aminobutyric acid receptor subunit pi GABRP
Gamma-aminobutyric acid receptor subunit theta GABRQ
Gamma-aminobutyric acid receptor subunit delta GABRD
Equilibrative nucleoside transporter 2 SLC29A2
5-hydroxytryptamine receptor 3E HTR3E
5-hydroxytryptamine receptor 3B HTR3B
5-hydroxytryptamine receptor 3D HTR3D
5-hydroxytryptamine receptor 3C HTR3C
Voltage-dependent calcium channel gamma-2 subunit CACNG2
G protein-activated inward rectifier potassium channel 3 KCNJ9
Neural cell adhesion molecule L1 L1CAM
Acetylcholinesterase ACHE
All-trans-retinol dehydrogenase [NAD(+)] ADH7 ADH7

Referensi & Sumber

Synthesis reference: William S. Hedrick, "Process for ethanol production from cellulosic materials." U.S. Patent US4650689, issued June, 1917.
Artikel (PubMed)
  • PMID: 7945890
    Snyder R, Kalf GF: A perspective on benzene leukemogenesis. Crit Rev Toxicol. 1994;24(3):177-209.
  • PMID: 17128954
    Chastain G: Alcohol, neurotransmitter systems, and behavior. J Gen Psychol. 2006 Oct;133(4):329-35.
  • PMID: 9880479
    McDonnell G, Russell AD: Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev. 1999 Jan;12(1):147-79.
  • PMID: 12216995
    Barceloux DG, Bond GR, Krenzelok EP, Cooper H, Vale JA: American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning. J Toxicol Clin Toxicol. 2002;40(4):415-46.
  • PMID: 15301401
    Hingson R, Winter M: Epidemiology and consequences of drinking and driving. Alcohol Res Health. 2003;27(1):63-78.

Contoh Produk & Brand

Produk: 22343 • International brands: 1
Produk
  • (Biotemed) Instant Hand Sanitizer
    Gel • 70 mL/100mL • Topical • US • OTC
  • (CPL) Hand Sanitiser
    Liquid • 80 mL/100mL • Topical • US • OTC
  • (ETHANOL62%) Dr keeps gel (ETHANOL)
    Gel • 62 mL/100mL • Topical • US • OTC
  • (ETHANOL70%) Dr keeps one gel (ETHANOL)
    Gel • 70 mL/100mL • Topical • US • OTC
  • (ETHANOL72%) Dr keeps 72 gel (ETHANOL)
    Gel • 72 mL/100mL • Topical • US • OTC
  • (ETHANOL72%) Dr keeps one gel (ETHANOL)
    Gel • 72 mL/100mL • Topical • US • OTC
  • (EZ-CARE) Hand Sanitizer
    Gel • 75 mL/100mL • Topical • US • OTC
  • (Fruli) 75% Alcohol Disinfectant
    Liquid • 80 mL/100mL • Topical • US • OTC
Menampilkan 8 dari 22343 produk.
International Brands
  • Dehydrated ethanol

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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