Peringatan Keamanan

Symptoms of overdose include bleeding in the eye or redness or swelling of the eye or the eyelid, blurred vision or other change in vision, fever or chills, itching or tearing, nausea or vomiting, pain, sensitivity to light, shortness of breath, sticky or matted eyelashes, swelling of face, throbbing pain, tightness in chest, troubled breathing, and wheezing.

Suprofen

DB00870

small molecule approved withdrawn

Deskripsi

An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.

Struktur Molekul 2D

Berat 260.308
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Primarily hepatic (mainly via cytochrome P450 isozyme 2C9).

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

166 Data
Aminosalicylic acid The therapeutic efficacy of Aminosalicylic acid can be decreased when used in combination with Suprofen.
Mesalazine The risk or severity of nephrotoxicity can be increased when Mesalazine is combined with Suprofen.
Sulfasalazine The therapeutic efficacy of Sulfasalazine can be decreased when used in combination with Suprofen.
Diflunisal The therapeutic efficacy of Diflunisal can be decreased when used in combination with Suprofen.
Acetylsalicylic acid The therapeutic efficacy of Acetylsalicylic acid can be decreased when used in combination with Suprofen.
Balsalazide The therapeutic efficacy of Balsalazide can be decreased when used in combination with Suprofen.
Olsalazine The risk or severity of nephrotoxicity can be increased when Suprofen is combined with Olsalazine.
Bismuth subsalicylate The therapeutic efficacy of Bismuth subsalicylate can be decreased when used in combination with Suprofen.
Dersalazine The therapeutic efficacy of Dersalazine can be decreased when used in combination with Suprofen.
Phenyl aminosalicylate The therapeutic efficacy of Phenyl aminosalicylate can be decreased when used in combination with Suprofen.
Methyl salicylate The therapeutic efficacy of Methyl salicylate can be decreased when used in combination with Suprofen.
Trolamine salicylate The therapeutic efficacy of Trolamine salicylate can be decreased when used in combination with Suprofen.
Nitroaspirin The therapeutic efficacy of Nitroaspirin can be decreased when used in combination with Suprofen.
Aloxiprin The therapeutic efficacy of Aloxiprin can be decreased when used in combination with Suprofen.
Guacetisal The therapeutic efficacy of Guacetisal can be decreased when used in combination with Suprofen.
Carbaspirin calcium The therapeutic efficacy of Carbaspirin calcium can be decreased when used in combination with Suprofen.
Choline salicylate The therapeutic efficacy of Choline salicylate can be decreased when used in combination with Suprofen.
Thiosalicylic acid The therapeutic efficacy of Thiosalicylic acid can be decreased when used in combination with Suprofen.
Diclofenac The risk or severity of adverse effects can be increased when Diclofenac is combined with Suprofen.
Flurbiprofen The risk or severity of adverse effects can be increased when Flurbiprofen is combined with Suprofen.
Bromfenac The risk or severity of adverse effects can be increased when Suprofen is combined with Bromfenac.
Nepafenac The risk or severity of adverse effects can be increased when Suprofen is combined with Nepafenac.
Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Suprofen.
Nabumetone The risk or severity of adverse effects can be increased when Nabumetone is combined with Suprofen.
Tenoxicam The risk or severity of adverse effects can be increased when Tenoxicam is combined with Suprofen.
Celecoxib The risk or severity of adverse effects can be increased when Celecoxib is combined with Suprofen.
Tolmetin The risk or severity of adverse effects can be increased when Tolmetin is combined with Suprofen.
Rofecoxib The risk or severity of adverse effects can be increased when Rofecoxib is combined with Suprofen.
Piroxicam The risk or severity of adverse effects can be increased when Piroxicam is combined with Suprofen.
Fenoprofen The risk or severity of adverse effects can be increased when Fenoprofen is combined with Suprofen.
Valdecoxib The risk or severity of adverse effects can be increased when Valdecoxib is combined with Suprofen.
Sulindac The risk or severity of adverse effects can be increased when Sulindac is combined with Suprofen.
Etodolac The risk or severity of adverse effects can be increased when Etodolac is combined with Suprofen.
Mefenamic acid The risk or severity of adverse effects can be increased when Mefenamic acid is combined with Suprofen.
Naproxen The risk or severity of adverse effects can be increased when Naproxen is combined with Suprofen.
Phenylbutazone The risk or severity of adverse effects can be increased when Phenylbutazone is combined with Suprofen.
Meloxicam The risk or severity of adverse effects can be increased when Meloxicam is combined with Suprofen.
Carprofen The risk or severity of adverse effects can be increased when Carprofen is combined with Suprofen.
Salicylic acid The risk or severity of adverse effects can be increased when Suprofen is combined with Salicylic acid.
Meclofenamic acid The risk or severity of adverse effects can be increased when Suprofen is combined with Meclofenamic acid.
Oxaprozin The risk or severity of adverse effects can be increased when Suprofen is combined with Oxaprozin.
Ketoprofen The risk or severity of adverse effects can be increased when Suprofen is combined with Ketoprofen.
Ibuprofen The risk or severity of adverse effects can be increased when Suprofen is combined with Ibuprofen.
Lumiracoxib The risk or severity of adverse effects can be increased when Suprofen is combined with Lumiracoxib.
Magnesium salicylate The risk or severity of adverse effects can be increased when Suprofen is combined with Magnesium salicylate.
Salsalate The risk or severity of adverse effects can be increased when Suprofen is combined with Salsalate.
Choline magnesium trisalicylate The risk or severity of adverse effects can be increased when Suprofen is combined with Choline magnesium trisalicylate.
Antipyrine The risk or severity of adverse effects can be increased when Suprofen is combined with Antipyrine.
Tiaprofenic acid The risk or severity of adverse effects can be increased when Suprofen is combined with Tiaprofenic acid.
Etoricoxib The risk or severity of adverse effects can be increased when Suprofen is combined with Etoricoxib.
Oxyphenbutazone The risk or severity of adverse effects can be increased when Suprofen is combined with Oxyphenbutazone.
Niflumic acid The risk or severity of adverse effects can be increased when Suprofen is combined with Niflumic acid.
Nimesulide The risk or severity of adverse effects can be increased when Suprofen is combined with Nimesulide.
Benoxaprofen The risk or severity of adverse effects can be increased when Suprofen is combined with Benoxaprofen.
Zomepirac The risk or severity of adverse effects can be increased when Suprofen is combined with Zomepirac.
Lornoxicam The risk or severity of adverse effects can be increased when Suprofen is combined with Lornoxicam.
Aceclofenac The risk or severity of adverse effects can be increased when Suprofen is combined with Aceclofenac.
Zaltoprofen The risk or severity of adverse effects can be increased when Suprofen is combined with Zaltoprofen.
Azapropazone The risk or severity of adverse effects can be increased when Suprofen is combined with Azapropazone.
Felbinac The risk or severity of adverse effects can be increased when Suprofen is combined with Felbinac.
Parecoxib The risk or severity of adverse effects can be increased when Suprofen is combined with Parecoxib.
Salicylamide The risk or severity of adverse effects can be increased when Suprofen is combined with Salicylamide.
Kebuzone The risk or severity of adverse effects can be increased when Suprofen is combined with Kebuzone.
Isoxicam The risk or severity of adverse effects can be increased when Suprofen is combined with Isoxicam.
Indoprofen The risk or severity of adverse effects can be increased when Suprofen is combined with Indoprofen.
Ibuproxam The risk or severity of adverse effects can be increased when Suprofen is combined with Ibuproxam.
Floctafenine The risk or severity of adverse effects can be increased when Suprofen is combined with Floctafenine.
Fenbufen The risk or severity of adverse effects can be increased when Suprofen is combined with Fenbufen.
Etofenamate The risk or severity of adverse effects can be increased when Suprofen is combined with Etofenamate.
Epirizole The risk or severity of adverse effects can be increased when Suprofen is combined with Epirizole.
Loxoprofen The risk or severity of adverse effects can be increased when Suprofen is combined with Loxoprofen.
Droxicam The risk or severity of adverse effects can be increased when Suprofen is combined with Droxicam.
Tolfenamic acid The risk or severity of adverse effects can be increased when Suprofen is combined with Tolfenamic acid.
Clonixin The risk or severity of adverse effects can be increased when Suprofen is combined with Clonixin.
Propacetamol The risk or severity of adverse effects can be increased when Suprofen is combined with Propacetamol.
Tepoxalin The risk or severity of adverse effects can be increased when Suprofen is combined with Tepoxalin.
Flunixin The risk or severity of adverse effects can be increased when Suprofen is combined with Flunixin.
Indobufen The risk or severity of adverse effects can be increased when Suprofen is combined with Indobufen.
Tinoridine The risk or severity of adverse effects can be increased when Suprofen is combined with Tinoridine.
Alclofenac The risk or severity of adverse effects can be increased when Suprofen is combined with Alclofenac.
Fentiazac The risk or severity of adverse effects can be increased when Suprofen is combined with Fentiazac.
Suxibuzone The risk or severity of adverse effects can be increased when Suprofen is combined with Suxibuzone.
Bumadizone The risk or severity of adverse effects can be increased when Suprofen is combined with Bumadizone.
Alminoprofen The risk or severity of adverse effects can be increased when Suprofen is combined with Alminoprofen.
Bufexamac The risk or severity of adverse effects can be increased when Suprofen is combined with Bufexamac.
Feprazone The risk or severity of adverse effects can be increased when Suprofen is combined with Feprazone.
Difenpiramide The risk or severity of adverse effects can be increased when Suprofen is combined with Difenpiramide.
Nifenazone The risk or severity of adverse effects can be increased when Suprofen is combined with Nifenazone.
Lonazolac The risk or severity of adverse effects can be increased when Suprofen is combined with Lonazolac.
Tenidap The risk or severity of adverse effects can be increased when Suprofen is combined with Tenidap.
Bendazac The risk or severity of adverse effects can be increased when Suprofen is combined with Bendazac.
Pranoprofen The risk or severity of adverse effects can be increased when Suprofen is combined with Pranoprofen.
Propyphenazone The risk or severity of adverse effects can be increased when Suprofen is combined with Propyphenazone.
Proglumetacin The risk or severity of adverse effects can be increased when Suprofen is combined with Proglumetacin.
Ethenzamide The risk or severity of adverse effects can be increased when Suprofen is combined with Ethenzamide.
Mofebutazone The risk or severity of adverse effects can be increased when Suprofen is combined with Mofebutazone.
Proquazone The risk or severity of adverse effects can be increased when Suprofen is combined with Proquazone.
Benorilate The risk or severity of adverse effects can be increased when Suprofen is combined with Benorilate.
Pirprofen The risk or severity of adverse effects can be increased when Suprofen is combined with Pirprofen.
Acemetacin The risk or severity of adverse effects can be increased when Suprofen is combined with Acemetacin.

Target Protein

Prostaglandin G/H synthase 1 PTGS1
Prostaglandin G/H synthase 2 PTGS2

Referensi & Sumber

Contoh Produk & Brand

Produk: 1 • International brands: 3
Produk
  • Profenal
    Solution • 10 mg/1 • Ophthalmic • US • Approved
International Brands
  • Srendam — Pola Pharma
  • Sulprotin — Taiyo Pharmaceutical
  • Topalgic — Alfresa Pharma

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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