Peringatan Keamanan

LD50=64mg/kg (mice, IV); LD50=540 mg/kg (mice, oral); LD50=85 mg/kg (rat, IV)

Ritodrine

DB00867

small molecule approved investigational

Deskripsi

Adrenergic beta-agonist used to control premature labor.

Struktur Molekul 2D

Berat 287.359
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 1.7-2.6 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Hepatic, by both the mother and fetus

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

817 Data
Valsartan Ritodrine may decrease the antihypertensive activities of Valsartan.
Ramipril Ritodrine may decrease the antihypertensive activities of Ramipril.
Reserpine Ritodrine may decrease the antihypertensive activities of Reserpine.
Remikiren Ritodrine may decrease the antihypertensive activities of Remikiren.
Isradipine Ritodrine may decrease the antihypertensive activities of Isradipine.
Olmesartan Ritodrine may decrease the antihypertensive activities of Olmesartan.
Nitroprusside Ritodrine may decrease the antihypertensive activities of Nitroprusside.
Diltiazem Ritodrine may decrease the antihypertensive activities of Diltiazem.
Minoxidil Ritodrine may decrease the antihypertensive activities of Minoxidil.
Treprostinil Ritodrine may decrease the antihypertensive activities of Treprostinil.
Amlodipine Ritodrine may decrease the antihypertensive activities of Amlodipine.
Nimodipine Ritodrine may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Ritodrine may decrease the antihypertensive activities of Nisoldipine.
Fosinopril Ritodrine may decrease the antihypertensive activities of Fosinopril.
Trandolapril Ritodrine may decrease the antihypertensive activities of Trandolapril.
Lercanidipine Ritodrine may decrease the antihypertensive activities of Lercanidipine.
Benazepril Ritodrine may decrease the antihypertensive activities of Benazepril.
Bosentan Ritodrine may decrease the antihypertensive activities of Bosentan.
Enalapril Ritodrine may decrease the antihypertensive activities of Enalapril.
Candoxatril Ritodrine may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Ritodrine may decrease the antihypertensive activities of Mecamylamine.
Losartan Ritodrine may decrease the antihypertensive activities of Losartan.
Moexipril Ritodrine may decrease the antihypertensive activities of Moexipril.
Eplerenone Ritodrine may decrease the antihypertensive activities of Eplerenone.
Lisinopril Ritodrine may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Ritodrine may decrease the antihypertensive activities of Nitroglycerin.
Metyrosine Ritodrine may decrease the antihypertensive activities of Metyrosine.
Cryptenamine Ritodrine may decrease the antihypertensive activities of Cryptenamine.
Perindopril Ritodrine may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Ritodrine may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Ritodrine may decrease the antihypertensive activities of Fenoldopam.
Tadalafil Ritodrine may decrease the antihypertensive activities of Tadalafil.
Eprosartan Ritodrine may decrease the antihypertensive activities of Eprosartan.
Quinapril Ritodrine may decrease the antihypertensive activities of Quinapril.
Telmisartan Ritodrine may decrease the antihypertensive activities of Telmisartan.
Methyldopa Ritodrine may decrease the antihypertensive activities of Methyldopa.
Irbesartan Ritodrine may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Ritodrine may decrease the antihypertensive activities of Nitrendipine.
Deserpidine Ritodrine may decrease the antihypertensive activities of Deserpidine.
Pentolinium Ritodrine may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Ritodrine may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Ritodrine may decrease the antihypertensive activities of Diazoxide.
Captopril Ritodrine may decrease the antihypertensive activities of Captopril.
Epoprostenol Ritodrine may decrease the antihypertensive activities of Epoprostenol.
Bepridil Ritodrine may decrease the antihypertensive activities of Bepridil.
Hydralazine Ritodrine may decrease the antihypertensive activities of Hydralazine.
Cilazapril Ritodrine may decrease the antihypertensive activities of Cilazapril.
Saprisartan Ritodrine may decrease the antihypertensive activities of Saprisartan.
Spirapril Ritodrine may decrease the antihypertensive activities of Spirapril.
Mibefradil Ritodrine may decrease the antihypertensive activities of Mibefradil.
Tienilic acid Ritodrine may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Ritodrine may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Ritodrine may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Ritodrine may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Ritodrine may decrease the antihypertensive activities of Diethylnorspermine.
Nilvadipine Ritodrine may decrease the antihypertensive activities of Nilvadipine.
Pinacidil Ritodrine may decrease the antihypertensive activities of Pinacidil.
Temocapril Ritodrine may decrease the antihypertensive activities of Temocapril.
Riociguat Ritodrine may decrease the antihypertensive activities of Riociguat.
Macitentan Ritodrine may decrease the antihypertensive activities of Macitentan.
Hexamethonium Ritodrine may decrease the antihypertensive activities of Hexamethonium.
Aliskiren Ritodrine may decrease the antihypertensive activities of Aliskiren.
Nicorandil Ritodrine may decrease the antihypertensive activities of Nicorandil.
Efonidipine Ritodrine may decrease the antihypertensive activities of Efonidipine.
Lacidipine Ritodrine may decrease the antihypertensive activities of Lacidipine.
Manidipine Ritodrine may decrease the antihypertensive activities of Manidipine.
Rauwolfia serpentina root Ritodrine may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Ritodrine may decrease the antihypertensive activities of Enalaprilat.
Selexipag Ritodrine may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Ritodrine may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Ritodrine may decrease the antihypertensive activities of Imidapril.
BQ-123 Ritodrine may decrease the antihypertensive activities of BQ-123.
Tetrahydropalmatine Ritodrine may decrease the antihypertensive activities of Tetrahydropalmatine.
Cicletanine Ritodrine may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Ritodrine may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Ritodrine may decrease the antihypertensive activities of Zofenopril.
Guanoxan Ritodrine may decrease the antihypertensive activities of Guanoxan.
Delapril Ritodrine may decrease the antihypertensive activities of Delapril.
Vincamine Ritodrine may decrease the antihypertensive activities of Vincamine.
Linsidomine Ritodrine may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Ritodrine may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Ritodrine may decrease the antihypertensive activities of Tolonidine.
Endralazine Ritodrine may decrease the antihypertensive activities of Endralazine.
Cadralazine Ritodrine may decrease the antihypertensive activities of Cadralazine.
Bietaserpine Ritodrine may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Ritodrine may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Ritodrine may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Ritodrine may decrease the antihypertensive activities of Guanoclor.
Muzolimine Ritodrine may decrease the antihypertensive activities of Muzolimine.
Xipamide Ritodrine may decrease the antihypertensive activities of Xipamide.
Candesartan Ritodrine may decrease the antihypertensive activities of Candesartan.
Dexniguldipine Ritodrine may decrease the antihypertensive activities of Dexniguldipine.
Tocopherylquinone Ritodrine may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Ritodrine may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Ritodrine may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Ritodrine may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Ritodrine may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Ritodrine may decrease the antihypertensive activities of Quinaprilat.
Felodipine Ritodrine may decrease the antihypertensive activities of Felodipine.
Levamlodipine Ritodrine may decrease the antihypertensive activities of Levamlodipine.

Target Protein

Beta-2 adrenergic receptor ADRB2
Beta adrenergic receptor ADRB1
ATP-sensitive potassium channel KCNJ1
Calcium-activated potassium channel KCNMA1
Calcium transporting ATPases ATP2C1
Myosin light chain kinase, smooth muscle MYLK
Sulfotransferase 1C4 SULT1C4

Referensi & Sumber

Synthesis reference: Naoki Yamazaki, Yoshimasa Fukuda, Yoshiaki Shibazaki, Tetsutarou Niizato, Isao Kosugi, Shin Yoshioka, "(-)-ritodrine, therapeutic compositions and use, and method of preparation." U.S. Patent US5449694, issued July, 1992.

Contoh Produk & Brand

Produk: 2 • International brands: 1
Produk
  • Yutopar Inj 50mg/5ml
    Liquid • 10 mg / mL • Intravenous • Canada • Approved
  • Yutopar Tab 10mg
    Tablet • 10 mg / tab • Oral • Canada • Approved
International Brands
  • Yutopar

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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