Peringatan Keamanan

LD50=160 mg/kg (orally in rats). Acute overdosage may result in restlessness, tremor, tachypnea, confusion, assaultiveness, and panic states.

Benzphetamine

DB00865

small molecule approved illicit

Deskripsi

A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)

Struktur Molekul 2D

Berat 239.3553
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 16 to 31 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Readily absorbed from the gastro-intestinal tract and buccal mucosa. It Is resistant to metabolism by monoamine oxidase.

Metabolisme

Hepatic. Benzphetamine's metabolites include amphetamine and methamphetamine.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Limit caffeine intake. Excess caffeine intake may increase the CNS stimulation caused by benzphetamine hydrochloride.

Interaksi Obat

1463 Data
Valsartan Benzphetamine may decrease the antihypertensive activities of Valsartan.
Ramipril Benzphetamine may decrease the antihypertensive activities of Ramipril.
Remikiren Benzphetamine may decrease the antihypertensive activities of Remikiren.
Torasemide Benzphetamine may decrease the antihypertensive activities of Torasemide.
Olmesartan Benzphetamine may decrease the antihypertensive activities of Olmesartan.
Chlorthalidone Benzphetamine may decrease the antihypertensive activities of Chlorthalidone.
Nitroprusside Benzphetamine may decrease the antihypertensive activities of Nitroprusside.
Minoxidil Benzphetamine may decrease the antihypertensive activities of Minoxidil.
Treprostinil Benzphetamine may decrease the antihypertensive activities of Treprostinil.
Bendroflumethiazide Benzphetamine may decrease the antihypertensive activities of Bendroflumethiazide.
Fosinopril Benzphetamine may decrease the antihypertensive activities of Fosinopril.
Trandolapril Benzphetamine may decrease the antihypertensive activities of Trandolapril.
Metolazone Benzphetamine may decrease the antihypertensive activities of Metolazone.
Benazepril Benzphetamine may decrease the antihypertensive activities of Benazepril.
Cyclothiazide Benzphetamine may decrease the antihypertensive activities of Cyclothiazide.
Candoxatril Benzphetamine may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Benzphetamine may decrease the antihypertensive activities of Mecamylamine.
Moexipril Benzphetamine may decrease the antihypertensive activities of Moexipril.
Lisinopril Benzphetamine may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Benzphetamine may decrease the antihypertensive activities of Nitroglycerin.
Hydroflumethiazide Benzphetamine may decrease the antihypertensive activities of Hydroflumethiazide.
Cryptenamine Benzphetamine may decrease the antihypertensive activities of Cryptenamine.
Perindopril Benzphetamine may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Benzphetamine may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Benzphetamine may decrease the antihypertensive activities of Fenoldopam.
Eprosartan Benzphetamine may decrease the antihypertensive activities of Eprosartan.
Chlorothiazide Benzphetamine may decrease the antihypertensive activities of Chlorothiazide.
Quinapril Benzphetamine may decrease the antihypertensive activities of Quinapril.
Telmisartan Benzphetamine may decrease the antihypertensive activities of Telmisartan.
Methyldopa Benzphetamine may decrease the antihypertensive activities of Methyldopa.
Hydrochlorothiazide Benzphetamine may decrease the antihypertensive activities of Hydrochlorothiazide.
Trichlormethiazide Benzphetamine may decrease the antihypertensive activities of Trichlormethiazide.
Deserpidine Benzphetamine may decrease the antihypertensive activities of Deserpidine.
Pentolinium Benzphetamine may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Benzphetamine may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Benzphetamine may decrease the antihypertensive activities of Diazoxide.
Captopril Benzphetamine may decrease the antihypertensive activities of Captopril.
Epoprostenol Benzphetamine may decrease the antihypertensive activities of Epoprostenol.
Polythiazide Benzphetamine may decrease the antihypertensive activities of Polythiazide.
Cilazapril Benzphetamine may decrease the antihypertensive activities of Cilazapril.
Saprisartan Benzphetamine may decrease the antihypertensive activities of Saprisartan.
Spirapril Benzphetamine may decrease the antihypertensive activities of Spirapril.
Tienilic acid Benzphetamine may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Benzphetamine may decrease the antihypertensive activities of Debrisoquine.
Diethylnorspermine Benzphetamine may decrease the antihypertensive activities of Diethylnorspermine.
Temocapril Benzphetamine may decrease the antihypertensive activities of Temocapril.
Nicorandil Benzphetamine may decrease the antihypertensive activities of Nicorandil.
Rauwolfia serpentina root Benzphetamine may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Benzphetamine may decrease the antihypertensive activities of Enalaprilat.
Angiotensin 1-7 Benzphetamine may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Benzphetamine may decrease the antihypertensive activities of Imidapril.
BQ-123 Benzphetamine may decrease the antihypertensive activities of BQ-123.
Cicletanine Benzphetamine may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Benzphetamine may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Benzphetamine may decrease the antihypertensive activities of Zofenopril.
Guanoxan Benzphetamine may decrease the antihypertensive activities of Guanoxan.
Delapril Benzphetamine may decrease the antihypertensive activities of Delapril.
Vincamine Benzphetamine may decrease the antihypertensive activities of Vincamine.
Linsidomine Benzphetamine may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Benzphetamine may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Benzphetamine may decrease the antihypertensive activities of Tolonidine.
Endralazine Benzphetamine may decrease the antihypertensive activities of Endralazine.
Cadralazine Benzphetamine may decrease the antihypertensive activities of Cadralazine.
Cyclopenthiazide Benzphetamine may decrease the antihypertensive activities of Cyclopenthiazide.
Bietaserpine Benzphetamine may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Benzphetamine may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Benzphetamine may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Benzphetamine may decrease the antihypertensive activities of Guanoclor.
Muzolimine Benzphetamine may decrease the antihypertensive activities of Muzolimine.
Xipamide Benzphetamine may decrease the antihypertensive activities of Xipamide.
Candesartan Benzphetamine may decrease the antihypertensive activities of Candesartan.
Tocopherylquinone Benzphetamine may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Benzphetamine may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Benzphetamine may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Benzphetamine may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Benzphetamine may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Benzphetamine may decrease the antihypertensive activities of Quinaprilat.
Furosemide Benzphetamine may decrease the antihypertensive activities of Furosemide.
Enalapril Benzphetamine may decrease the antihypertensive activities of Enalapril.
Nimodipine Benzphetamine may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Benzphetamine may decrease the antihypertensive activities of Nisoldipine.
Lercanidipine Benzphetamine may decrease the antihypertensive activities of Lercanidipine.
Bosentan Benzphetamine may decrease the antihypertensive activities of Bosentan.
Losartan Benzphetamine may decrease the antihypertensive activities of Losartan.
Eplerenone Benzphetamine may decrease the antihypertensive activities of Eplerenone.
Indapamide Benzphetamine may decrease the antihypertensive activities of Indapamide.
Tadalafil Benzphetamine may decrease the antihypertensive activities of Tadalafil.
Felodipine Benzphetamine may decrease the antihypertensive activities of Felodipine.
Irbesartan Benzphetamine may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Benzphetamine may decrease the antihypertensive activities of Nitrendipine.
Bepridil Benzphetamine may decrease the antihypertensive activities of Bepridil.
Hydralazine Benzphetamine may decrease the antihypertensive activities of Hydralazine.
Mibefradil Benzphetamine may decrease the antihypertensive activities of Mibefradil.
Sitaxentan Benzphetamine may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Benzphetamine may decrease the antihypertensive activities of Ambrisentan.
Pinacidil Benzphetamine may decrease the antihypertensive activities of Pinacidil.
Riociguat Benzphetamine may decrease the antihypertensive activities of Riociguat.
Macitentan Benzphetamine may decrease the antihypertensive activities of Macitentan.
Aliskiren Benzphetamine may decrease the antihypertensive activities of Aliskiren.
Efonidipine Benzphetamine may decrease the antihypertensive activities of Efonidipine.

Target Protein

Synaptic vesicular amine transporter SLC18A2
Alpha-2A adrenergic receptor ADRA2A
Alpha-1A adrenergic receptor ADRA1A
Sodium-dependent dopamine transporter SLC6A3

Referensi & Sumber

Synthesis reference: Dennis J. Kalota, Keith G. Tomazi, "Crystallization Method for Benzphetamine." U.S. Patent US20080262268, issued October 23, 2008.

Contoh Produk & Brand

Produk: 35 • International brands: 0
Produk
  • Benzphetamine
    Tablet • 25 mg/1 • Oral • US • Generic • Approved
  • Benzphetamine Hydrochloride
    Tablet • 50 mg/1 • Oral • US • Generic • Approved
  • Benzphetamine Hydrochloride
    Tablet • 50 mg/1 • Oral • US • Generic • Approved
  • Benzphetamine Hydrochloride
    Tablet, coated • 50 mg/1 • Oral • US • Generic • Approved
  • Benzphetamine Hydrochloride
    Tablet • 50 mg/1 • Oral • US • Generic • Approved
  • Benzphetamine Hydrochloride
    Tablet, coated • 50 mg/1 • Oral • US • Generic • Approved
  • Benzphetamine Hydrochloride
    Tablet • 50 mg/1 • Oral • US • Generic • Approved
  • Benzphetamine Hydrochloride
    Tablet • 25 mg/1 • Oral • US • Generic • Approved
Menampilkan 8 dari 35 produk.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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