Symptoms of overdose include stupor or coma, and children may have convulsive seizures. Signs of arousal may not occur for 48 hours. Oral LD50=318 mg/kg (rat); IPR LD50=64 mg/kg (mouse)
An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Deferasirox | The serum concentration of Perphenazine can be increased when it is combined with Deferasirox. |
| Peginterferon alfa-2b | The serum concentration of Perphenazine can be increased when it is combined with Peginterferon alfa-2b. |
| Leflunomide | The serum concentration of Perphenazine can be decreased when it is combined with Leflunomide. |
| Teriflunomide | The serum concentration of Perphenazine can be decreased when it is combined with Teriflunomide. |
| Buprenorphine | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Perphenazine. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Perphenazine. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Perphenazine. |
| Hydrocodone | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Perphenazine. |
| Magnesium sulfate | The therapeutic efficacy of Perphenazine can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Perphenazine. |
| Mirtazapine | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Perphenazine. |
| Orphenadrine | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Perphenazine. |
| Rotigotine | Perphenazine may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Perphenazine. |
| Sodium oxybate | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Suvorexant | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Perphenazine. |
| Thalidomide | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Amisulpride | Perphenazine may increase the antipsychotic activities of Amisulpride. |
| Methylphenidate | The risk or severity of adverse effects can be increased when Perphenazine is combined with Methylphenidate. |
| Dexmethylphenidate | The risk or severity of adverse effects can be increased when Perphenazine is combined with Dexmethylphenidate. |
| Metoclopramide | The risk or severity of adverse effects can be increased when Metoclopramide is combined with Perphenazine. |
| Quinagolide | The therapeutic efficacy of Quinagolide can be decreased when used in combination with Perphenazine. |
| Sulpiride | Perphenazine may increase the antipsychotic activities of Sulpiride. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Perphenazine. |
| Lithium citrate | Lithium citrate may increase the neurotoxic activities of Perphenazine. |
| Lithium hydroxide | Lithium hydroxide may increase the neurotoxic activities of Perphenazine. |
| Mequitazine | Perphenazine may increase the arrhythmogenic activities of Mequitazine. |
| Thiopental | The risk or severity of adverse effects can be increased when Perphenazine is combined with Thiopental. |
| Atomoxetine | The metabolism of Atomoxetine can be decreased when combined with Perphenazine. |
| Metyrosine | The risk or severity of extrapyramidal symptoms and CNS depression can be increased when Metyrosine is combined with Perphenazine. |
| Mirabegron | The serum concentration of Perphenazine can be increased when it is combined with Mirabegron. |
| Abiraterone | The serum concentration of Perphenazine can be increased when it is combined with Abiraterone. |
| Cyproterone acetate | The metabolism of Perphenazine can be increased when combined with Cyproterone acetate. |
| Ethanol | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Ethanol. |
| Azelastine | Perphenazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine. |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Perphenazine. |
| Zimelidine | The risk or severity of adverse effects can be increased when Perphenazine is combined with Zimelidine. |
| Dapoxetine | The risk or severity of adverse effects can be increased when Perphenazine is combined with Dapoxetine. |
| Seproxetine | The risk or severity of adverse effects can be increased when Perphenazine is combined with Seproxetine. |
| Citalopram | The risk or severity of adverse effects can be increased when Perphenazine is combined with Citalopram. |
| Trazodone | The risk or severity of adverse effects can be increased when Perphenazine is combined with Trazodone. |
| Sertraline | The risk or severity of adverse effects can be increased when Perphenazine is combined with Sertraline. |
| Sibutramine | The risk or severity of adverse effects can be increased when Perphenazine is combined with Sibutramine. |
| Nefazodone | The risk or severity of adverse effects can be increased when Perphenazine is combined with Nefazodone. |
| Milnacipran | The risk or severity of adverse effects can be increased when Perphenazine is combined with Milnacipran. |
| Desvenlafaxine | The serum concentration of Perphenazine can be increased when it is combined with Desvenlafaxine. |
| Levomilnacipran | The risk or severity of adverse effects can be increased when Levomilnacipran is combined with Perphenazine. |
| Indalpine | The risk or severity of adverse effects can be increased when Perphenazine is combined with Indalpine. |
| Alaproclate | The risk or severity of adverse effects can be increased when Perphenazine is combined with Alaproclate. |
| Esmolol | The serum concentration of Esmolol can be increased when it is combined with Perphenazine. |
| Betaxolol | The serum concentration of Betaxolol can be increased when it is combined with Perphenazine. |
| Atenolol | The serum concentration of Atenolol can be increased when it is combined with Perphenazine. |
| Propranolol | The serum concentration of Propranolol can be increased when it is combined with Perphenazine. |
| Labetalol | The serum concentration of Labetalol can be increased when it is combined with Perphenazine. |
| Bisoprolol | The serum concentration of Bisoprolol can be increased when it is combined with Perphenazine. |
| Alprenolol | The serum concentration of Alprenolol can be increased when it is combined with Perphenazine. |
| Pindolol | The serum concentration of Pindolol can be increased when it is combined with Perphenazine. |
| Carvedilol | The serum concentration of Carvedilol can be increased when it is combined with Perphenazine. |
| Acebutolol | The serum concentration of Acebutolol can be increased when it is combined with Perphenazine. |
| Nadolol | The serum concentration of Nadolol can be increased when it is combined with Perphenazine. |
| Bevantolol | The serum concentration of Bevantolol can be increased when it is combined with Perphenazine. |
| Practolol | The serum concentration of Practolol can be increased when it is combined with Perphenazine. |
| Penbutolol | The serum concentration of Penbutolol can be increased when it is combined with Perphenazine. |
| Oxprenolol | The serum concentration of Oxprenolol can be increased when it is combined with Perphenazine. |
| Dexpropranolol | The serum concentration of Dexpropranolol can be increased when it is combined with Perphenazine. |
| Celiprolol | The serum concentration of Celiprolol can be increased when it is combined with Perphenazine. |
| Nebivolol | The serum concentration of Nebivolol can be increased when it is combined with Perphenazine. |
| Bufuralol | The serum concentration of Bufuralol can be increased when it is combined with Perphenazine. |
| Bopindolol | The serum concentration of Bopindolol can be increased when it is combined with Perphenazine. |
| Bupranolol | The serum concentration of Bupranolol can be increased when it is combined with Perphenazine. |
| Indenolol | The serum concentration of Indenolol can be increased when it is combined with Perphenazine. |
| Arotinolol | The serum concentration of Arotinolol can be increased when it is combined with Perphenazine. |
| Levobetaxolol | The serum concentration of Levobetaxolol can be increased when it is combined with Perphenazine. |
| Talinolol | The serum concentration of Talinolol can be increased when it is combined with Perphenazine. |
| Anisodamine | The serum concentration of Anisodamine can be increased when it is combined with Perphenazine. |
| Bucindolol | The serum concentration of Bucindolol can be increased when it is combined with Perphenazine. |
| Esatenolol | The serum concentration of Esatenolol can be increased when it is combined with Perphenazine. |
| Cloranolol | The serum concentration of Cloranolol can be increased when it is combined with Perphenazine. |
| Mepindolol | The serum concentration of Mepindolol can be increased when it is combined with Perphenazine. |
| Epanolol | The serum concentration of Epanolol can be increased when it is combined with Perphenazine. |
| Tertatolol | The serum concentration of Tertatolol can be increased when it is combined with Perphenazine. |
| Morphine | The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Morphine. |
| Codeine | The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Codeine. |
| Hydromorphone | The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Hydromorphone. |
| Oxycodone | The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Oxycodone. |
| Butorphanol | The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Butorphanol. |
| Dextropropoxyphene | The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Dextropropoxyphene. |
| Pentazocine | The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Pentazocine. |
| Naltrexone | The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Naltrexone. |
| Sufentanil | The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Sufentanil. |
| Nalbuphine | The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Nalbuphine. |
| Levorphanol | The risk or severity of hypotension and CNS depression can be increased when Perphenazine is combined with Levorphanol. |