A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Aripiprazole | The metabolism of Aripiprazole can be increased when combined with Methylphenobarbital. |
| Aripiprazole lauroxil | The metabolism of Aripiprazole lauroxil can be increased when combined with Methylphenobarbital. |
| Buprenorphine | Methylphenobarbital may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Methylphenobarbital. |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Methylphenobarbital. |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Methylphenobarbital. |
| Hydrocodone | Methylphenobarbital may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Methylphenobarbital. |
| Magnesium sulfate | The therapeutic efficacy of Methylphenobarbital can be increased when used in combination with Magnesium sulfate. |
| Methotrimeprazine | Methylphenobarbital may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. |
| Metyrosine | Methylphenobarbital may increase the sedative activities of Metyrosine. |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Methylphenobarbital. |
| Mirtazapine | Methylphenobarbital may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Methylphenobarbital. |
| Orphenadrine | Methylphenobarbital may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. |
| Paraldehyde | Methylphenobarbital may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. |
| Pramipexole | Methylphenobarbital may increase the sedative activities of Pramipexole. |
| Ropinirole | Methylphenobarbital may increase the sedative activities of Ropinirole. |
| Rotigotine | Methylphenobarbital may increase the sedative activities of Rotigotine. |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Methylphenobarbital. |
| Suvorexant | Methylphenobarbital may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Methylphenobarbital. |
| Thalidomide | Methylphenobarbital may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. |
| Zolpidem | Methylphenobarbital may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. |
| Amphetamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Amphetamine. |
| Phentermine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Phentermine. |
| Pseudoephedrine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Pseudoephedrine. |
| Benzphetamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Benzphetamine. |
| Diethylpropion | The serum concentration of Methylphenobarbital can be decreased when it is combined with Diethylpropion. |
| Lisdexamfetamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Lisdexamfetamine. |
| Mephentermine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Mephentermine. |
| MMDA | The serum concentration of Methylphenobarbital can be decreased when it is combined with MMDA. |
| Midomafetamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Midomafetamine. |
| 2,5-Dimethoxy-4-ethylamphetamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with 2,5-Dimethoxy-4-ethylamphetamine. |
| 4-Bromo-2,5-dimethoxyamphetamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with 4-Bromo-2,5-dimethoxyamphetamine. |
| Tenamfetamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Tenamfetamine. |
| Chlorphentermine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Chlorphentermine. |
| Methylenedioxyethamphetamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Methylenedioxyethamphetamine. |
| Dextroamphetamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Dextroamphetamine. |
| Metamfetamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Metamfetamine. |
| Iofetamine I-123 | The serum concentration of Methylphenobarbital can be decreased when it is combined with Iofetamine I-123. |
| Ritobegron | The serum concentration of Methylphenobarbital can be decreased when it is combined with Ritobegron. |
| Mephedrone | The serum concentration of Methylphenobarbital can be decreased when it is combined with Mephedrone. |
| Methoxyphenamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Methoxyphenamine. |
| Gepefrine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Gepefrine. |
| 2,5-Dimethoxy-4-ethylthioamphetamine | The serum concentration of Methylphenobarbital can be decreased when it is combined with 2,5-Dimethoxy-4-ethylthioamphetamine. |
| Phendimetrazine | The serum concentration of Methylphenobarbital can be decreased when it is combined with Phendimetrazine. |
| Dabrafenib | The serum concentration of Methylphenobarbital can be decreased when it is combined with Dabrafenib. |
| Secretin porcine | The therapeutic efficacy of Secretin porcine can be decreased when used in combination with Methylphenobarbital. |
| Luliconazole | The serum concentration of Methylphenobarbital can be increased when it is combined with Luliconazole. |
| Mefloquine | The therapeutic efficacy of Methylphenobarbital can be decreased when used in combination with Mefloquine. |
| Orlistat | Orlistat can cause a decrease in the absorption of Methylphenobarbital resulting in a reduced serum concentration and potentially a decrease in efficacy. |
| Acetaminophen | The metabolism of Acetaminophen can be increased when combined with Methylphenobarbital. |
| Propacetamol | The metabolism of Propacetamol can be increased when combined with Methylphenobarbital. |
| Chloramphenicol | The metabolism of Methylphenobarbital can be decreased when combined with Chloramphenicol. |
| Doxycycline | The serum concentration of Doxycycline can be decreased when it is combined with Methylphenobarbital. |
| Griseofulvin | The serum concentration of Griseofulvin can be decreased when it is combined with Methylphenobarbital. |
| Mianserin | The therapeutic efficacy of Methylphenobarbital can be decreased when used in combination with Mianserin. |
| Butalbital | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Butalbital. |
| Pentobarbital | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Pentobarbital. |
| Secobarbital | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Secobarbital. |
| Methohexital | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Methohexital. |
| Thiopental | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Thiopental. |
| Thiamylal | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Thiamylal. |
| Amobarbital | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Amobarbital. |
| Hexobarbital | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Hexobarbital. |
| Barbital | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Barbital. |
| Barbexaclone | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Barbexaclone. |
| Pyridoxine | The metabolism of Methylphenobarbital can be increased when combined with Pyridoxine. |
| Teniposide | The serum concentration of Teniposide can be decreased when it is combined with Methylphenobarbital. |
| Ulipristal | The serum concentration of Ulipristal can be decreased when it is combined with Methylphenobarbital. |
| Voriconazole | The serum concentration of Voriconazole can be decreased when it is combined with Methylphenobarbital. |
| Metyrapone | The serum concentration of Metyrapone can be decreased when it is combined with Methylphenobarbital. |
| Topotecan | Methylphenobarbital may increase the excretion rate of Topotecan which could result in a lower serum level and potentially a reduction in efficacy. |
| Acetazolamide | The serum concentration of Methylphenobarbital can be decreased when it is combined with Acetazolamide. |
| Valproic acid | The serum concentration of Phenobarbital, an active metabolite of Methylphenobarbital, can be increased when used in combination with Valproic acid. |
| Methadone | The risk or severity of adverse effects can be increased when Methadone is combined with Methylphenobarbital. |
| Sodium oxybate | Methylphenobarbital may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate. |
| Methylphenidate | The serum concentration of Methylphenobarbital can be increased when it is combined with Methylphenidate. |
| Dexmethylphenidate | The serum concentration of Methylphenobarbital can be increased when it is combined with Dexmethylphenidate. |
| Quinine | The serum concentration of Methylphenobarbital can be increased when it is combined with Quinine. |
| Quinidine | The serum concentration of Methylphenobarbital can be increased when it is combined with Quinidine. |
| Lamotrigine | Methylphenobarbital may increase the excretion rate of Lamotrigine which could result in a lower serum level and potentially a reduction in efficacy. |
| Ifosfamide | The metabolism of Ifosfamide can be increased when combined with Methylphenobarbital. |
| Perampanel | The metabolism of Perampanel can be increased when combined with Methylphenobarbital. |
| Warfarin | The metabolism of Warfarin can be increased when combined with Methylphenobarbital. |
| Acenocoumarol | The metabolism of Acenocoumarol can be increased when combined with Methylphenobarbital. |
| (R)-warfarin | The metabolism of (R)-warfarin can be increased when combined with Methylphenobarbital. |
| R,S-Warfarin alcohol | The metabolism of R,S-Warfarin alcohol can be increased when combined with Methylphenobarbital. |
| S,R-Warfarin alcohol | The metabolism of S,R-Warfarin alcohol can be increased when combined with Methylphenobarbital. |
| (S)-Warfarin | The metabolism of (S)-Warfarin can be increased when combined with Methylphenobarbital. |
| Cobicistat | The serum concentration of Cobicistat can be decreased when it is combined with Methylphenobarbital. |
| Tetracosactide | The risk or severity of liver damage can be increased when Tetracosactide is combined with Methylphenobarbital. |
| Etravirine | The metabolism of Etravirine can be increased when combined with Methylphenobarbital. |
| Felbamate | The serum concentration of Phenobarbital, an active metabolite of Methylphenobarbital, can be increased when used in combination with Felbamate. |
| Boceprevir | The serum concentration of Boceprevir can be decreased when it is combined with Methylphenobarbital. |
| Canagliflozin | The serum concentration of Canagliflozin can be decreased when it is combined with Methylphenobarbital. |
| Deferasirox | The serum concentration of Deferasirox can be decreased when it is combined with Methylphenobarbital. |
| Lacosamide | The metabolism of Lacosamide can be increased when combined with Methylphenobarbital. |
| Stiripentol | The serum concentration of Stiripentol can be decreased when it is combined with Methylphenobarbital. |