Dobutamine

DB00841

small molecule approved

Deskripsi

A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.

Struktur Molekul 2D

Berat 301.3801
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 2 minutes
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

In human urine, the major excretion products are the conjugates of dobutamine and 3-O-methyl dobutamine.

Interaksi Obat

1327 Data
Valsartan Dobutamine may decrease the antihypertensive activities of Valsartan.
Ramipril Dobutamine may decrease the antihypertensive activities of Ramipril.
Remikiren Dobutamine may decrease the antihypertensive activities of Remikiren.
Olmesartan Dobutamine may decrease the antihypertensive activities of Olmesartan.
Diltiazem Dobutamine may decrease the antihypertensive activities of Diltiazem.
Minoxidil Dobutamine may decrease the antihypertensive activities of Minoxidil.
Treprostinil Dobutamine may decrease the antihypertensive activities of Treprostinil.
Amlodipine Dobutamine may decrease the antihypertensive activities of Amlodipine.
Nimodipine Dobutamine may decrease the antihypertensive activities of Nimodipine.
Trandolapril Dobutamine may decrease the antihypertensive activities of Trandolapril.
Lercanidipine Dobutamine may decrease the antihypertensive activities of Lercanidipine.
Benazepril Dobutamine may decrease the antihypertensive activities of Benazepril.
Bosentan Dobutamine may decrease the antihypertensive activities of Bosentan.
Enalapril Dobutamine may decrease the antihypertensive activities of Enalapril.
Candoxatril Dobutamine may decrease the antihypertensive activities of Candoxatril.
Losartan Dobutamine may decrease the antihypertensive activities of Losartan.
Moexipril Dobutamine may decrease the antihypertensive activities of Moexipril.
Nitroglycerin Dobutamine may decrease the antihypertensive activities of Nitroglycerin.
Metyrosine Dobutamine may decrease the antihypertensive activities of Metyrosine.
Cryptenamine Dobutamine may decrease the antihypertensive activities of Cryptenamine.
Candesartan cilexetil Dobutamine may decrease the antihypertensive activities of Candesartan cilexetil.
Eprosartan Dobutamine may decrease the antihypertensive activities of Eprosartan.
Quinapril Dobutamine may decrease the antihypertensive activities of Quinapril.
Telmisartan Dobutamine may decrease the antihypertensive activities of Telmisartan.
Irbesartan Dobutamine may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Dobutamine may decrease the antihypertensive activities of Nitrendipine.
Deserpidine Dobutamine may decrease the antihypertensive activities of Deserpidine.
Pentolinium Dobutamine may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Dobutamine may decrease the antihypertensive activities of Trimethaphan.
Captopril Dobutamine may decrease the antihypertensive activities of Captopril.
Bepridil Dobutamine may decrease the antihypertensive activities of Bepridil.
Cilazapril Dobutamine may decrease the antihypertensive activities of Cilazapril.
Saprisartan Dobutamine may decrease the antihypertensive activities of Saprisartan.
Spirapril Dobutamine may decrease the antihypertensive activities of Spirapril.
Mibefradil Dobutamine may decrease the antihypertensive activities of Mibefradil.
Debrisoquine Dobutamine may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Dobutamine may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Dobutamine may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Dobutamine may decrease the antihypertensive activities of Diethylnorspermine.
Nilvadipine Dobutamine may decrease the antihypertensive activities of Nilvadipine.
Pinacidil Dobutamine may decrease the antihypertensive activities of Pinacidil.
Temocapril Dobutamine may decrease the antihypertensive activities of Temocapril.
Riociguat Dobutamine may decrease the antihypertensive activities of Riociguat.
Hexamethonium Dobutamine may decrease the antihypertensive activities of Hexamethonium.
Aliskiren Dobutamine may decrease the antihypertensive activities of Aliskiren.
Lacidipine Dobutamine may decrease the antihypertensive activities of Lacidipine.
Manidipine Dobutamine may decrease the antihypertensive activities of Manidipine.
Rauwolfia serpentina root Dobutamine may decrease the antihypertensive activities of Rauwolfia serpentina root.
Selexipag Dobutamine may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Dobutamine may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Dobutamine may decrease the antihypertensive activities of Imidapril.
BQ-123 Dobutamine may decrease the antihypertensive activities of BQ-123.
Tetrahydropalmatine Dobutamine may decrease the antihypertensive activities of Tetrahydropalmatine.
Dihydralazine Dobutamine may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Dobutamine may decrease the antihypertensive activities of Zofenopril.
Guanoxan Dobutamine may decrease the antihypertensive activities of Guanoxan.
Delapril Dobutamine may decrease the antihypertensive activities of Delapril.
Vincamine Dobutamine may decrease the antihypertensive activities of Vincamine.
Linsidomine Dobutamine may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Dobutamine may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Dobutamine may decrease the antihypertensive activities of Tolonidine.
Endralazine Dobutamine may decrease the antihypertensive activities of Endralazine.
Cadralazine Dobutamine may decrease the antihypertensive activities of Cadralazine.
Bietaserpine Dobutamine may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Dobutamine may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Dobutamine may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Dobutamine may decrease the antihypertensive activities of Guanoclor.
Candesartan Dobutamine may decrease the antihypertensive activities of Candesartan.
Dexniguldipine Dobutamine may decrease the antihypertensive activities of Dexniguldipine.
Tocopherylquinone Dobutamine may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Dobutamine may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Dobutamine may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Dobutamine may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Dobutamine may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Dobutamine may decrease the antihypertensive activities of Quinaprilat.
Felodipine Dobutamine may decrease the antihypertensive activities of Felodipine.
Levamlodipine Dobutamine may decrease the antihypertensive activities of Levamlodipine.
Azilsartan medoxomil Dobutamine may decrease the antihypertensive activities of Azilsartan medoxomil.
Diazoxide Dobutamine may decrease the antihypertensive activities of Diazoxide.
Linezolid The risk or severity of hypertension can be increased when Linezolid is combined with Dobutamine.
Benzylpenicilloyl polylysine Dobutamine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent.
Eletriptan The risk or severity of hypertension can be increased when Eletriptan is combined with Dobutamine.
Bethanidine Dobutamine may decrease the antihypertensive activities of Bethanidine.
Zolmitriptan The risk or severity of hypertension can be increased when Zolmitriptan is combined with Dobutamine.
Mirtazapine The risk or severity of hypertension can be increased when Mirtazapine is combined with Dobutamine.
Doxapram The risk or severity of hypertension can be increased when Doxapram is combined with Dobutamine.
Atropine The risk or severity of hypertension can be increased when Atropine is combined with Dobutamine.
Clonidine Dobutamine may decrease the antihypertensive activities of Clonidine.
Guanabenz Dobutamine may decrease the antihypertensive activities of Guanabenz.
Sufentanil The risk or severity of hypertension can be increased when Sufentanil is combined with Dobutamine.
Isoflurane The risk or severity of hypertension can be increased when Isoflurane is combined with Dobutamine.
Alfentanil The risk or severity of hypertension can be increased when Alfentanil is combined with Dobutamine.
Propofol The risk or severity of hypertension can be increased when Propofol is combined with Dobutamine.
Omapatrilat Dobutamine may decrease the antihypertensive activities of Omapatrilat.
Remifentanil The risk or severity of hypertension can be increased when Dobutamine is combined with Remifentanil.
Naratriptan The risk or severity of hypertension can be increased when Dobutamine is combined with Naratriptan.
Frovatriptan The risk or severity of hypertension can be increased when Dobutamine is combined with Frovatriptan.
Methoxyflurane The risk or severity of hypertension can be increased when Dobutamine is combined with Methoxyflurane.
Dutasteride The risk or severity of hypertension can be increased when Dobutamine is combined with Dutasteride.
Halothane The risk or severity of hypertension can be increased when Dobutamine is combined with Halothane.

Target Protein

Alpha-1 adrenergic receptors ADRA1A
Beta-1 adrenergic receptor ADRB1
Beta-2 adrenergic receptor ADRB2
Estrogen receptor ESR1

Referensi & Sumber

Synthesis reference: R. R. Tuttle, J. Mills, DE 2317710 (1973). J. Mills, R. R. Tuttle, U.S. Patent 3,987,200 (1976).

Contoh Produk & Brand

Produk: 33 • International brands: 8
Produk
  • Dobutamine
    Injection, solution • 12.5 mg/1mL • Intravenous • US • Generic • Approved
  • DOBUTamine
    Injection, solution, concentrate • 12.5 mg/1mL • Intravenous • US • Generic • Approved
  • Dobutamine
    Injection • 12.5 mg/1mL • Intravenous • US • Generic • Approved
  • Dobutamine
    Injection, solution • 12.5 mg/1mL • Intravenous • US • Generic • Approved
  • Dobutamine
    Injection, solution, concentrate • 12.5 mg/1mL • Intravenous • US • Generic • Approved
  • Dobutamine
    Injection, solution, concentrate • 12.5 mg/1mL • Intravenous • US • Generic • Approved
  • Dobutamine
    Injection, solution • 200 mg/100mL • Intravenous • US • Approved
  • Dobutamine
    Injection, solution • 12.5 mg/1mL • Intravenous • US • Generic • Approved
Menampilkan 8 dari 33 produk.
International Brands
  • Dobuject — Bayer
  • Dobusafe — Claris
  • Dobutamin — Sandoz
  • Dobutan — Demo
  • Dobutel — Novell
  • Dobutil — Meizler
  • Dopmin — Mylan Seiyaku
  • Inotrex — Lilly

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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