Peringatan Keamanan

Symptoms of overdose include agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, and restlessness.

Trifluoperazine

DB00831

small molecule approved investigational

Deskripsi

A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.

Struktur Molekul 2D

Berat 407.496
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 10-20 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Hepatic.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Avoid excessive or chronic alcohol consumption. Ingesting alcohol may potentiate the sedative and CNS depressant effects of trifluoperazine.

Interaksi Obat

1451 Data
Deferasirox The serum concentration of Trifluoperazine can be increased when it is combined with Deferasirox.
Peginterferon alfa-2b The serum concentration of Trifluoperazine can be increased when it is combined with Peginterferon alfa-2b.
Leflunomide The serum concentration of Trifluoperazine can be decreased when it is combined with Leflunomide.
Teriflunomide The serum concentration of Trifluoperazine can be decreased when it is combined with Teriflunomide.
Valsartan Trifluoperazine may decrease the antihypertensive activities of Valsartan.
Ramipril Trifluoperazine may decrease the antihypertensive activities of Ramipril.
Remikiren Trifluoperazine may decrease the antihypertensive activities of Remikiren.
Torasemide Trifluoperazine may decrease the antihypertensive activities of Torasemide.
Guanadrel Trifluoperazine may decrease the antihypertensive activities of Guanadrel.
Olmesartan Trifluoperazine may decrease the antihypertensive activities of Olmesartan.
Chlorthalidone Trifluoperazine may decrease the antihypertensive activities of Chlorthalidone.
Nitroprusside Trifluoperazine may decrease the antihypertensive activities of Nitroprusside.
Minoxidil Trifluoperazine may decrease the antihypertensive activities of Minoxidil.
Treprostinil Trifluoperazine may decrease the antihypertensive activities of Treprostinil.
Bendroflumethiazide Trifluoperazine may decrease the antihypertensive activities of Bendroflumethiazide.
Fosinopril Trifluoperazine may decrease the antihypertensive activities of Fosinopril.
Trandolapril Trifluoperazine may decrease the antihypertensive activities of Trandolapril.
Metolazone Trifluoperazine may decrease the antihypertensive activities of Metolazone.
Benazepril Trifluoperazine may decrease the antihypertensive activities of Benazepril.
Bosentan Trifluoperazine may decrease the antihypertensive activities of Bosentan.
Cyclothiazide Trifluoperazine may decrease the antihypertensive activities of Cyclothiazide.
Candoxatril Trifluoperazine may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Trifluoperazine may decrease the antihypertensive activities of Mecamylamine.
Moexipril Trifluoperazine may decrease the antihypertensive activities of Moexipril.
Eplerenone Trifluoperazine may decrease the antihypertensive activities of Eplerenone.
Lisinopril Trifluoperazine may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Trifluoperazine may decrease the antihypertensive activities of Nitroglycerin.
Hydroflumethiazide Trifluoperazine may decrease the antihypertensive activities of Hydroflumethiazide.
Cryptenamine Trifluoperazine may decrease the antihypertensive activities of Cryptenamine.
Perindopril Trifluoperazine may decrease the antihypertensive activities of Perindopril.
Indapamide Trifluoperazine may decrease the antihypertensive activities of Indapamide.
Eprosartan Trifluoperazine may decrease the antihypertensive activities of Eprosartan.
Chlorothiazide Trifluoperazine may decrease the antihypertensive activities of Chlorothiazide.
Quinapril Trifluoperazine may decrease the antihypertensive activities of Quinapril.
Hydrochlorothiazide Trifluoperazine may decrease the antihypertensive activities of Hydrochlorothiazide.
Trichlormethiazide Trifluoperazine may decrease the antihypertensive activities of Trichlormethiazide.
Irbesartan Trifluoperazine may decrease the antihypertensive activities of Irbesartan.
Deserpidine Trifluoperazine may decrease the antihypertensive activities of Deserpidine.
Pentolinium Trifluoperazine may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Trifluoperazine may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Trifluoperazine may decrease the antihypertensive activities of Diazoxide.
Bretylium Trifluoperazine may decrease the antihypertensive activities of Bretylium.
Guanethidine Trifluoperazine may decrease the antihypertensive activities of Guanethidine.
Epoprostenol Trifluoperazine may decrease the antihypertensive activities of Epoprostenol.
Hydralazine Trifluoperazine may decrease the antihypertensive activities of Hydralazine.
Polythiazide Trifluoperazine may decrease the antihypertensive activities of Polythiazide.
Saprisartan Trifluoperazine may decrease the antihypertensive activities of Saprisartan.
Spirapril Trifluoperazine may decrease the antihypertensive activities of Spirapril.
Tienilic acid Trifluoperazine may decrease the antihypertensive activities of Tienilic acid.
Sitaxentan Trifluoperazine may decrease the antihypertensive activities of Sitaxentan.
Diethylnorspermine Trifluoperazine may decrease the antihypertensive activities of Diethylnorspermine.
Pinacidil Trifluoperazine may decrease the antihypertensive activities of Pinacidil.
Temocapril Trifluoperazine may decrease the antihypertensive activities of Temocapril.
Riociguat Trifluoperazine may decrease the antihypertensive activities of Riociguat.
Macitentan Trifluoperazine may decrease the antihypertensive activities of Macitentan.
Aliskiren Trifluoperazine may decrease the antihypertensive activities of Aliskiren.
Nicorandil Trifluoperazine may decrease the antihypertensive activities of Nicorandil.
Rauwolfia serpentina root Trifluoperazine may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Trifluoperazine may decrease the antihypertensive activities of Enalaprilat.
Angiotensin 1-7 Trifluoperazine may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Trifluoperazine may decrease the antihypertensive activities of Imidapril.
BQ-123 Trifluoperazine may decrease the antihypertensive activities of BQ-123.
Cicletanine Trifluoperazine may decrease the antihypertensive activities of Cicletanine.
Zofenopril Trifluoperazine may decrease the antihypertensive activities of Zofenopril.
Guanoxan Trifluoperazine may decrease the antihypertensive activities of Guanoxan.
Delapril Trifluoperazine may decrease the antihypertensive activities of Delapril.
Vincamine Trifluoperazine may decrease the antihypertensive activities of Vincamine.
Linsidomine Trifluoperazine may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Trifluoperazine may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Trifluoperazine may decrease the antihypertensive activities of Tolonidine.
Endralazine Trifluoperazine may decrease the antihypertensive activities of Endralazine.
Cadralazine Trifluoperazine may decrease the antihypertensive activities of Cadralazine.
Cyclopenthiazide Trifluoperazine may decrease the antihypertensive activities of Cyclopenthiazide.
Bietaserpine Trifluoperazine may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Trifluoperazine may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Trifluoperazine may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Trifluoperazine may decrease the antihypertensive activities of Guanoclor.
Muzolimine Trifluoperazine may decrease the antihypertensive activities of Muzolimine.
Xipamide Trifluoperazine may decrease the antihypertensive activities of Xipamide.
Tocopherylquinone Trifluoperazine may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Trifluoperazine may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Trifluoperazine may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Trifluoperazine may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Trifluoperazine may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Trifluoperazine may decrease the antihypertensive activities of Quinaprilat.
Furosemide Trifluoperazine may decrease the antihypertensive activities of Furosemide.
Enalapril Trifluoperazine may decrease the antihypertensive activities of Enalapril.
Losartan Trifluoperazine may decrease the antihypertensive activities of Losartan.
Candesartan cilexetil Trifluoperazine may decrease the antihypertensive activities of Candesartan cilexetil.
Telmisartan Trifluoperazine may decrease the antihypertensive activities of Telmisartan.
Captopril Trifluoperazine may decrease the antihypertensive activities of Captopril.
Cilazapril Trifluoperazine may decrease the antihypertensive activities of Cilazapril.
Debrisoquine Trifluoperazine may decrease the antihypertensive activities of Debrisoquine.
Ambrisentan Trifluoperazine may decrease the antihypertensive activities of Ambrisentan.
Selexipag Trifluoperazine may decrease the antihypertensive activities of Selexipag.
Candesartan Trifluoperazine may decrease the antihypertensive activities of Candesartan.
Levamlodipine Trifluoperazine may decrease the antihypertensive activities of Levamlodipine.
Buthiazide Trifluoperazine may decrease the antihypertensive activities of Buthiazide.
Azilsartan medoxomil Trifluoperazine may decrease the antihypertensive activities of Azilsartan medoxomil.
Buprenorphine Trifluoperazine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.

Target Protein

D(2) dopamine receptor DRD2
Calmodulin-1 CALM1
Calmodulin-3 CALM3
Calmodulin-2 CALM2
Neuron-specific vesicular protein calcyon CALY
Alpha-1A adrenergic receptor ADRA1A
Troponin C, slow skeletal and cardiac muscles TNNC1
Protein S100-A4 S100A4
Calmodulin CALM1

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 81 • International brands: 8
Produk
  • Novo-flurazine Tab 1mg
    Tablet • 1.18 mg / tab • Oral • Canada • Generic • Approved
  • Novo-flurazine Tab 20mg
    Tablet • 23.6 mg / tab • Oral • Canada • Generic • Approved
  • Novo-trifluzine - Tab 10mg
    Tablet • 11.8 mg • Oral • Canada • Generic • Approved
  • Novo-trifluzine - Tab 2mg
    Tablet • 2.36 mg • Oral • Canada • Generic • Approved
  • Novo-trifluzine - Tab 5mg
    Tablet • 5.9 mg • Oral • Canada • Generic • Approved
  • PMS Trifluoperazine HCl Syrup 11.8mg/ml
    Syrup • 10 mg / mL • Oral • Canada • Generic • Approved
  • PMS Trifluoperazine Tab 10mg
    Tablet • 10 mg • Oral • Canada • Generic • Approved
  • PMS Trifluoperazine Tab 1mg
    Tablet • 1 mg / tab • Oral • Canada • Generic • Approved
Menampilkan 8 dari 81 produk.
International Brands
  • Eskazine
  • Eskazinyl
  • Jatroneural
  • Modalina
  • Stelazine
  • Terfluzine
  • Trifluoperaz
  • Triftazin

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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