Ethynodiol diacetate

DB00823

small molecule approved

Deskripsi

A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that has never been marketed, see DB13866).

Struktur Molekul 2D

Berat 384.5085
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

600 Data
Acitretin The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Acitretin.
Aprepitant The serum concentration of Ethynodiol diacetate can be decreased when it is combined with Aprepitant.
Atazanavir The serum concentration of Ethynodiol diacetate can be increased when it is combined with Atazanavir.
Boceprevir The serum concentration of Ethynodiol diacetate can be increased when it is combined with Boceprevir.
Prucalopride The serum concentration of Ethynodiol diacetate can be decreased when it is combined with Prucalopride.
Sugammadex The serum concentration of Ethynodiol diacetate can be decreased when it is combined with Sugammadex.
Thalidomide Ethynodiol diacetate may increase the thrombogenic activities of Thalidomide.
Ulipristal The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Ulipristal.
Ursodeoxycholic acid The therapeutic efficacy of Ursodeoxycholic acid can be decreased when used in combination with Ethynodiol diacetate.
Glycochenodeoxycholic Acid The therapeutic efficacy of Glycochenodeoxycholic Acid can be decreased when used in combination with Ethynodiol diacetate.
Cholic Acid The therapeutic efficacy of Cholic Acid can be decreased when used in combination with Ethynodiol diacetate.
Glycocholic acid The therapeutic efficacy of Glycocholic acid can be decreased when used in combination with Ethynodiol diacetate.
Deoxycholic acid The therapeutic efficacy of Deoxycholic acid can be decreased when used in combination with Ethynodiol diacetate.
Taurocholic acid The therapeutic efficacy of Taurocholic acid can be decreased when used in combination with Ethynodiol diacetate.
Obeticholic acid The therapeutic efficacy of Obeticholic acid can be decreased when used in combination with Ethynodiol diacetate.
Tauroursodeoxycholic acid The therapeutic efficacy of Tauroursodeoxycholic acid can be decreased when used in combination with Ethynodiol diacetate.
Bamet-UD2 The therapeutic efficacy of Bamet-UD2 can be decreased when used in combination with Ethynodiol diacetate.
cis-Diamminechlorocholylglycinateplatinum(II) The therapeutic efficacy of cis-Diamminechlorocholylglycinateplatinum(II) can be decreased when used in combination with Ethynodiol diacetate.
Dehydrocholic acid The therapeutic efficacy of Dehydrocholic acid can be decreased when used in combination with Ethynodiol diacetate.
Hyodeoxycholic Acid The therapeutic efficacy of Hyodeoxycholic Acid can be decreased when used in combination with Ethynodiol diacetate.
Aramchol The therapeutic efficacy of Aramchol can be decreased when used in combination with Ethynodiol diacetate.
Ox bile extract The therapeutic efficacy of Ox bile extract can be decreased when used in combination with Ethynodiol diacetate.
Chenodeoxycholic acid The therapeutic efficacy of Chenodeoxycholic acid can be decreased when used in combination with Ethynodiol diacetate.
Taurochenodeoxycholic acid The therapeutic efficacy of Taurochenodeoxycholic acid can be decreased when used in combination with Ethynodiol diacetate.
Tranexamic acid Ethynodiol diacetate may increase the thrombogenic activities of Tranexamic acid.
Clobazam The serum concentration of Ethynodiol diacetate can be decreased when it is combined with Clobazam.
Colestipol Colestipol can cause a decrease in the absorption of Ethynodiol diacetate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sevelamer Sevelamer can cause a decrease in the absorption of Ethynodiol diacetate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Colesevelam Colesevelam can cause a decrease in the absorption of Ethynodiol diacetate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cholestyramine Cholestyramine can cause a decrease in the absorption of Ethynodiol diacetate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Griseofulvin The metabolism of Ethynodiol diacetate can be increased when combined with Griseofulvin.
Tixocortol The serum concentration of Tixocortol can be increased when it is combined with Ethynodiol diacetate.
Fluocortin The serum concentration of Fluocortin can be increased when it is combined with Ethynodiol diacetate.
Fluperolone The serum concentration of Fluperolone can be increased when it is combined with Ethynodiol diacetate.
Fluclorolone The serum concentration of Fluclorolone can be increased when it is combined with Ethynodiol diacetate.
Flunisolide The serum concentration of Flunisolide can be increased when it is combined with Ethynodiol diacetate.
Beclomethasone dipropionate The serum concentration of Beclomethasone dipropionate can be increased when it is combined with Ethynodiol diacetate.
Betamethasone The serum concentration of Betamethasone can be increased when it is combined with Ethynodiol diacetate.
Fluocinolone acetonide The serum concentration of Fluocinolone acetonide can be increased when it is combined with Ethynodiol diacetate.
Triamcinolone The serum concentration of Triamcinolone can be increased when it is combined with Ethynodiol diacetate.
Prednisone The serum concentration of Prednisone can be increased when it is combined with Ethynodiol diacetate.
Hydrocortisone The serum concentration of Hydrocortisone can be increased when it is combined with Ethynodiol diacetate.
Prednisolone The serum concentration of Prednisolone can be increased when it is combined with Ethynodiol diacetate.
Methylprednisolone The serum concentration of Methylprednisolone can be increased when it is combined with Ethynodiol diacetate.
Corticotropin The serum concentration of Corticotropin can be increased when it is combined with Ethynodiol diacetate.
Cortisone acetate The serum concentration of Cortisone acetate can be increased when it is combined with Ethynodiol diacetate.
Fluprednidene The serum concentration of Fluprednidene can be increased when it is combined with Ethynodiol diacetate.
Meprednisone The serum concentration of Meprednisone can be increased when it is combined with Ethynodiol diacetate.
Dexamethasone isonicotinate The serum concentration of Dexamethasone isonicotinate can be increased when it is combined with Ethynodiol diacetate.
Deflazacort The serum concentration of Deflazacort can be increased when it is combined with Ethynodiol diacetate.
Cortivazol The serum concentration of Cortivazol can be increased when it is combined with Ethynodiol diacetate.
Prednylidene The serum concentration of Prednylidene can be increased when it is combined with Ethynodiol diacetate.
Cloprednol The serum concentration of Cloprednol can be increased when it is combined with Ethynodiol diacetate.
Mometasone furoate The serum concentration of Mometasone furoate can be increased when it is combined with Ethynodiol diacetate.
Hydrocortisone acetate The serum concentration of Hydrocortisone acetate can be increased when it is combined with Ethynodiol diacetate.
Hydrocortisone succinate The serum concentration of Hydrocortisone succinate can be increased when it is combined with Ethynodiol diacetate.
Prednisolone phosphate The serum concentration of Prednisolone phosphate can be increased when it is combined with Ethynodiol diacetate.
Prednisolone hemisuccinate The serum concentration of Prednisolone hemisuccinate can be increased when it is combined with Ethynodiol diacetate.
Methylprednisolone hemisuccinate The serum concentration of Methylprednisolone hemisuccinate can be increased when it is combined with Ethynodiol diacetate.
Prednisone acetate The serum concentration of Prednisone acetate can be increased when it is combined with Ethynodiol diacetate.
Clocortolone acetate The serum concentration of Clocortolone acetate can be increased when it is combined with Ethynodiol diacetate.
Melengestrol acetate The serum concentration of Melengestrol acetate can be increased when it is combined with Ethynodiol diacetate.
Betamethasone phosphate The serum concentration of Betamethasone phosphate can be increased when it is combined with Ethynodiol diacetate.
Cortisone The serum concentration of Cortisone can be increased when it is combined with Ethynodiol diacetate.
Fluticasone propionate The serum concentration of Fluticasone propionate can be increased when it is combined with Ethynodiol diacetate.
Fludrocortisone The serum concentration of Fludrocortisone can be increased when it is combined with Ethynodiol diacetate.
Trilostane The serum concentration of Trilostane can be increased when it is combined with Ethynodiol diacetate.
Budesonide The serum concentration of Budesonide can be increased when it is combined with Ethynodiol diacetate.
Dexamethasone The serum concentration of Dexamethasone can be increased when it is combined with Ethynodiol diacetate.
Paramethasone The serum concentration of Paramethasone can be increased when it is combined with Ethynodiol diacetate.
Ciclesonide The serum concentration of Ciclesonide can be increased when it is combined with Ethynodiol diacetate.
Aldosterone The serum concentration of Aldosterone can be increased when it is combined with Ethynodiol diacetate.
Fluticasone furoate The serum concentration of Fluticasone furoate can be increased when it is combined with Ethynodiol diacetate.
Fluprednisolone The serum concentration of Fluprednisolone can be increased when it is combined with Ethynodiol diacetate.
Melengestrol The serum concentration of Melengestrol can be increased when it is combined with Ethynodiol diacetate.
Fluticasone The serum concentration of Fluticasone can be increased when it is combined with Ethynodiol diacetate.
Hydrocortisone cypionate The serum concentration of Hydrocortisone cypionate can be increased when it is combined with Ethynodiol diacetate.
Clobetasol propionate The serum concentration of Clobetasol propionate can be increased when it is combined with Ethynodiol diacetate.
Fluocinonide The serum concentration of Fluocinonide can be increased when it is combined with Ethynodiol diacetate.
Hydrocortisone butyrate The serum concentration of Hydrocortisone butyrate can be increased when it is combined with Ethynodiol diacetate.
Desoximetasone The serum concentration of Desoximetasone can be increased when it is combined with Ethynodiol diacetate.
Mometasone The serum concentration of Mometasone can be increased when it is combined with Ethynodiol diacetate.
Fluocortolone The serum concentration of Fluocortolone can be increased when it is combined with Ethynodiol diacetate.
Prednisolone acetate The serum concentration of Prednisolone acetate can be increased when it is combined with Ethynodiol diacetate.
Fluorometholone The serum concentration of Fluorometholone can be increased when it is combined with Ethynodiol diacetate.
Difluocortolone The serum concentration of Difluocortolone can be increased when it is combined with Ethynodiol diacetate.
Flumethasone The serum concentration of Flumethasone can be increased when it is combined with Ethynodiol diacetate.
Methylprednisolone aceponate The serum concentration of Methylprednisolone aceponate can be increased when it is combined with Ethynodiol diacetate.
Vitamin A The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Vitamin A.
Bexarotene The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Bexarotene.
Alitretinoin The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Alitretinoin.
Tretinoin The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Tretinoin.
Tazarotene The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Tazarotene.
Etretinate The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Etretinate.
Isotretinoin The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Isotretinoin.
4-Oxoretinol The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with 4-Oxoretinol.
Fenretinide The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Fenretinide.
Ro 12-7310 The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Ro 12-7310.
Zuretinol acetate The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Zuretinol acetate.
Motretinide The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Motretinide.

Target Protein

Progesterone receptor PGR
Estrogen receptor ESR1

Referensi & Sumber

Synthesis reference: Klimstra, P.D.; U.S. Patent 3,176,013; March 30, 1965; assigned to G.D. Searle & Co.

Contoh Produk & Brand

Produk: 18 • International brands: 7
Produk
  • Demulen 30 (21 Day Pack)
    Tablet • - • Oral • Canada • Approved
  • Demulen 30 (28 Day Pack)
    Tablet • - • Oral • Canada • Approved
  • Demulen 50 (21 Day Pack)
    Tablet • - • Oral • Canada • Approved
  • Demulen 50 (28 Day Pack)
    Tablet • - • Oral • Canada • Approved
  • Ethynodiol Diacetate and Ethinyl Estradiol
    Kit • - • Oral • US • Generic • Approved
  • Ethynodiol Diacetate and Ethinyl Estradiol
    Kit • - • Oral • US • Generic • Approved
  • Kelnor 1/35
    Kit • - • Oral • US • Generic • Approved
  • Kelnor 1/35
    Kit; Tablet • - • Oral • US • Generic • Approved
Menampilkan 8 dari 18 produk.
International Brands
  • Conova — Searle
  • Continuin
  • Dernulen — Searle
  • Femulen — Pfizer
  • Luteonorm
  • Luto-Metrodiol
  • Metrodiol

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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