Rosoxacin

DB00817

small molecule approved investigational

Deskripsi

Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with penicillin, especially anaphylactic shock.

Struktur Molekul 2D

Berat 294.3047
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

935 Data
Didanosine Didanosine can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Probenecid Probenecid may decrease the excretion rate of Rosoxacin which could result in a higher serum level.
Quinapril Quinapril can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium acetate Calcium acetate can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sevelamer Sevelamer can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron Dextran Iron Dextran can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium Calcium can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium carbonate Calcium carbonate can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum carbonate Lanthanum carbonate can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric carboxymaltose Ferric carboxymaltose can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron sucrose Iron sucrose can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric pyrophosphate Ferric pyrophosphate can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium citrate Calcium citrate can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium gluconate Calcium gluconate can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric sulfate Ferric sulfate can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric cation Ferric cation can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Tetraferric tricitrate decahydrate Tetraferric tricitrate decahydrate can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum III cation Lanthanum III cation can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium polycarbophil Calcium polycarbophil can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric oxyhydroxide Ferric oxyhydroxide can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sucralfate Sucralfate can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Rosoxacin.
Nitrofurantoin The therapeutic efficacy of Rosoxacin can be decreased when used in combination with Nitrofurantoin.
Mycophenolate mofetil The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Rosoxacin.
Mycophenolic acid The serum concentration of Mycophenolic acid can be decreased when it is combined with Rosoxacin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Rosoxacin.
Insulin human The therapeutic efficacy of Insulin human can be increased when used in combination with Rosoxacin.
Insulin lispro The therapeutic efficacy of Insulin lispro can be increased when used in combination with Rosoxacin.
Insulin pork The therapeutic efficacy of Insulin pork can be increased when used in combination with Rosoxacin.
Troglitazone The therapeutic efficacy of Troglitazone can be increased when used in combination with Rosoxacin.
Glimepiride The therapeutic efficacy of Glimepiride can be increased when used in combination with Rosoxacin.
Sulfisoxazole The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Rosoxacin.
Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Rosoxacin.
Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Rosoxacin.
Sulfadiazine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Rosoxacin.
Rosiglitazone The therapeutic efficacy of Rosiglitazone can be increased when used in combination with Rosoxacin.
Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Rosoxacin.
Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Rosoxacin.
Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Rosoxacin.
Nateglinide The therapeutic efficacy of Nateglinide can be increased when used in combination with Rosoxacin.
Pentamidine The therapeutic efficacy of Pentamidine can be increased when used in combination with Rosoxacin.
Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Rosoxacin.
Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Rosoxacin.
Phenformin The therapeutic efficacy of Phenformin can be increased when used in combination with Rosoxacin.
Sulfamethoxazole The therapeutic efficacy of Sulfamethoxazole can be increased when used in combination with Rosoxacin.
Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Rosoxacin.
Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Rosoxacin.
Gliclazide The therapeutic efficacy of Gliclazide can be increased when used in combination with Rosoxacin.
Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Rosoxacin.
Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Rosoxacin.
Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Rosoxacin.
Gliquidone The therapeutic efficacy of Gliquidone can be increased when used in combination with Rosoxacin.
Mitiglinide The therapeutic efficacy of Mitiglinide can be increased when used in combination with Rosoxacin.
Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Rosoxacin.
Sunitinib The therapeutic efficacy of Sunitinib can be increased when used in combination with Rosoxacin.
Exenatide The therapeutic efficacy of Exenatide can be increased when used in combination with Rosoxacin.
Mecasermin The therapeutic efficacy of Mecasermin can be increased when used in combination with Rosoxacin.
Pramlintide The therapeutic efficacy of Pramlintide can be increased when used in combination with Rosoxacin.
Glisoxepide The therapeutic efficacy of Glisoxepide can be increased when used in combination with Rosoxacin.
Insulin aspart The therapeutic efficacy of Insulin aspart can be increased when used in combination with Rosoxacin.
Insulin glulisine The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Rosoxacin.
Glymidine The therapeutic efficacy of Glymidine can be increased when used in combination with Rosoxacin.
AICA ribonucleotide The therapeutic efficacy of AICA ribonucleotide can be increased when used in combination with Rosoxacin.
Buformin The therapeutic efficacy of Buformin can be increased when used in combination with Rosoxacin.
Vildagliptin The therapeutic efficacy of Vildagliptin can be increased when used in combination with Rosoxacin.
Voglibose The therapeutic efficacy of Voglibose can be increased when used in combination with Rosoxacin.
NN344 The therapeutic efficacy of NN344 can be increased when used in combination with Rosoxacin.
AMG-222 The therapeutic efficacy of AMG-222 can be increased when used in combination with Rosoxacin.
Bisegliptin The therapeutic efficacy of Bisegliptin can be increased when used in combination with Rosoxacin.
Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Rosoxacin.
Dapagliflozin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Rosoxacin.
Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Rosoxacin.
Liraglutide The therapeutic efficacy of Liraglutide can be increased when used in combination with Rosoxacin.
Gosogliptin The therapeutic efficacy of Gosogliptin can be increased when used in combination with Rosoxacin.
Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Rosoxacin.
Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Rosoxacin.
Glibornuride The therapeutic efficacy of Glibornuride can be increased when used in combination with Rosoxacin.
Benfluorex The therapeutic efficacy of Benfluorex can be increased when used in combination with Rosoxacin.
Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Rosoxacin.
Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Rosoxacin.
Dulaglutide The therapeutic efficacy of Dulaglutide can be increased when used in combination with Rosoxacin.
Lobeglitazone The therapeutic efficacy of Lobeglitazone can be increased when used in combination with Rosoxacin.
Netoglitazone The therapeutic efficacy of Netoglitazone can be increased when used in combination with Rosoxacin.
Rivoglitazone The therapeutic efficacy of Rivoglitazone can be increased when used in combination with Rosoxacin.
Ciglitazone The therapeutic efficacy of Ciglitazone can be increased when used in combination with Rosoxacin.
Lixisenatide The therapeutic efficacy of Lixisenatide can be increased when used in combination with Rosoxacin.
Insulin beef The therapeutic efficacy of Insulin beef can be increased when used in combination with Rosoxacin.
Insulin degludec The therapeutic efficacy of Insulin degludec can be increased when used in combination with Rosoxacin.
Insulin peglispro The therapeutic efficacy of Insulin peglispro can be increased when used in combination with Rosoxacin.
Insulin tregopil The therapeutic efficacy of Insulin tregopil can be increased when used in combination with Rosoxacin.
Ipragliflozin The therapeutic efficacy of Ipragliflozin can be increased when used in combination with Rosoxacin.
Dutogliptin The therapeutic efficacy of Dutogliptin can be increased when used in combination with Rosoxacin.
Allicin The therapeutic efficacy of Allicin can be increased when used in combination with Rosoxacin.
Tofogliflozin The therapeutic efficacy of Tofogliflozin can be increased when used in combination with Rosoxacin.
Ertugliflozin The therapeutic efficacy of Ertugliflozin can be increased when used in combination with Rosoxacin.
2,4-thiazolidinedione The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Rosoxacin.
Teneligliptin The therapeutic efficacy of Teneligliptin can be increased when used in combination with Rosoxacin.
Omarigliptin The therapeutic efficacy of Omarigliptin can be increased when used in combination with Rosoxacin.
Carmegliptin The therapeutic efficacy of Carmegliptin can be increased when used in combination with Rosoxacin.
Gemigliptin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Rosoxacin.

Target Protein

DNA topoisomerase 2-alpha TOP2A
DNA topoisomerase 2-beta TOP2B
DNA gyrase subunit B gyrB
DNA topoisomerase 4 subunit A parC

Referensi & Sumber

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Contoh Produk & Brand

Produk: 0 • International brands: 2
International Brands
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Sekuens Gen/Protein (FASTA)

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