Peringatan Keamanan

Symptoms of overdose include angina, hypertension or hypotension, arrhythmias, nervousness, headache, tremor, dry mouth, palpitation, nausea, dizziness, fatigue, malaise and insomnia. LD50=42 mg/kg (orally in rat).

Orciprenaline

DB00816

small molecule approved

Deskripsi

A beta-adrenergic agonist used in the treatment of asthma and bronchospasms. PubChem

Struktur Molekul 2D

Berat 211.2576
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) 6 hours
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

3% (oral bioavailability of 40%)

Metabolisme

Hepatic and gastric. The major metabolite, orciprenaline-3-0-sulfate, is produced in the gastrointestinal tract. Orciprenaline is not metabolized by catechol-0-methyltransferase nor have glucuronide conjugates been isolated to date.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

2 Data
  • 1. Limit caffeine intake.
  • 2. Take with or without food. The absorption is unaffected by food.

Interaksi Obat

819 Data
Loxapine The therapeutic efficacy of Orciprenaline can be decreased when used in combination with Loxapine.
Valsartan Orciprenaline may decrease the antihypertensive activities of Valsartan.
Ramipril Orciprenaline may decrease the antihypertensive activities of Ramipril.
Reserpine Orciprenaline may decrease the antihypertensive activities of Reserpine.
Remikiren Orciprenaline may decrease the antihypertensive activities of Remikiren.
Isradipine Orciprenaline may decrease the antihypertensive activities of Isradipine.
Olmesartan Orciprenaline may decrease the antihypertensive activities of Olmesartan.
Nitroprusside Orciprenaline may decrease the antihypertensive activities of Nitroprusside.
Diltiazem Orciprenaline may decrease the antihypertensive activities of Diltiazem.
Minoxidil Orciprenaline may decrease the antihypertensive activities of Minoxidil.
Treprostinil Orciprenaline may decrease the antihypertensive activities of Treprostinil.
Amlodipine Orciprenaline may decrease the antihypertensive activities of Amlodipine.
Nimodipine Orciprenaline may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Orciprenaline may decrease the antihypertensive activities of Nisoldipine.
Fosinopril Orciprenaline may decrease the antihypertensive activities of Fosinopril.
Trandolapril Orciprenaline may decrease the antihypertensive activities of Trandolapril.
Lercanidipine Orciprenaline may decrease the antihypertensive activities of Lercanidipine.
Benazepril Orciprenaline may decrease the antihypertensive activities of Benazepril.
Bosentan Orciprenaline may decrease the antihypertensive activities of Bosentan.
Enalapril Orciprenaline may decrease the antihypertensive activities of Enalapril.
Candoxatril Orciprenaline may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Orciprenaline may decrease the antihypertensive activities of Mecamylamine.
Losartan Orciprenaline may decrease the antihypertensive activities of Losartan.
Moexipril Orciprenaline may decrease the antihypertensive activities of Moexipril.
Eplerenone Orciprenaline may decrease the antihypertensive activities of Eplerenone.
Lisinopril Orciprenaline may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Orciprenaline may decrease the antihypertensive activities of Nitroglycerin.
Metyrosine Orciprenaline may decrease the antihypertensive activities of Metyrosine.
Cryptenamine Orciprenaline may decrease the antihypertensive activities of Cryptenamine.
Perindopril Orciprenaline may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Orciprenaline may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Orciprenaline may decrease the antihypertensive activities of Fenoldopam.
Tadalafil Orciprenaline may decrease the antihypertensive activities of Tadalafil.
Eprosartan Orciprenaline may decrease the antihypertensive activities of Eprosartan.
Quinapril Orciprenaline may decrease the antihypertensive activities of Quinapril.
Telmisartan Orciprenaline may decrease the antihypertensive activities of Telmisartan.
Methyldopa Orciprenaline may decrease the antihypertensive activities of Methyldopa.
Irbesartan Orciprenaline may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Orciprenaline may decrease the antihypertensive activities of Nitrendipine.
Deserpidine Orciprenaline may decrease the antihypertensive activities of Deserpidine.
Pentolinium Orciprenaline may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Orciprenaline may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Orciprenaline may decrease the antihypertensive activities of Diazoxide.
Captopril Orciprenaline may decrease the antihypertensive activities of Captopril.
Epoprostenol Orciprenaline may decrease the antihypertensive activities of Epoprostenol.
Bepridil Orciprenaline may decrease the antihypertensive activities of Bepridil.
Hydralazine Orciprenaline may decrease the antihypertensive activities of Hydralazine.
Cilazapril Orciprenaline may decrease the antihypertensive activities of Cilazapril.
Saprisartan Orciprenaline may decrease the antihypertensive activities of Saprisartan.
Spirapril Orciprenaline may decrease the antihypertensive activities of Spirapril.
Mibefradil Orciprenaline may decrease the antihypertensive activities of Mibefradil.
Tienilic acid Orciprenaline may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Orciprenaline may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Orciprenaline may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Orciprenaline may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Orciprenaline may decrease the antihypertensive activities of Diethylnorspermine.
Nilvadipine Orciprenaline may decrease the antihypertensive activities of Nilvadipine.
Pinacidil Orciprenaline may decrease the antihypertensive activities of Pinacidil.
Temocapril Orciprenaline may decrease the antihypertensive activities of Temocapril.
Riociguat Orciprenaline may decrease the antihypertensive activities of Riociguat.
Macitentan Orciprenaline may decrease the antihypertensive activities of Macitentan.
Hexamethonium Orciprenaline may decrease the antihypertensive activities of Hexamethonium.
Aliskiren Orciprenaline may decrease the antihypertensive activities of Aliskiren.
Nicorandil Orciprenaline may decrease the antihypertensive activities of Nicorandil.
Efonidipine Orciprenaline may decrease the antihypertensive activities of Efonidipine.
Lacidipine Orciprenaline may decrease the antihypertensive activities of Lacidipine.
Manidipine Orciprenaline may decrease the antihypertensive activities of Manidipine.
Rauwolfia serpentina root Orciprenaline may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Orciprenaline may decrease the antihypertensive activities of Enalaprilat.
Selexipag Orciprenaline may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Orciprenaline may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Orciprenaline may decrease the antihypertensive activities of Imidapril.
BQ-123 Orciprenaline may decrease the antihypertensive activities of BQ-123.
Tetrahydropalmatine Orciprenaline may decrease the antihypertensive activities of Tetrahydropalmatine.
Cicletanine Orciprenaline may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Orciprenaline may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Orciprenaline may decrease the antihypertensive activities of Zofenopril.
Guanoxan Orciprenaline may decrease the antihypertensive activities of Guanoxan.
Delapril Orciprenaline may decrease the antihypertensive activities of Delapril.
Vincamine Orciprenaline may decrease the antihypertensive activities of Vincamine.
Linsidomine Orciprenaline may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Orciprenaline may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Orciprenaline may decrease the antihypertensive activities of Tolonidine.
Endralazine Orciprenaline may decrease the antihypertensive activities of Endralazine.
Cadralazine Orciprenaline may decrease the antihypertensive activities of Cadralazine.
Bietaserpine Orciprenaline may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Orciprenaline may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Orciprenaline may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Orciprenaline may decrease the antihypertensive activities of Guanoclor.
Muzolimine Orciprenaline may decrease the antihypertensive activities of Muzolimine.
Xipamide Orciprenaline may decrease the antihypertensive activities of Xipamide.
Candesartan Orciprenaline may decrease the antihypertensive activities of Candesartan.
Dexniguldipine Orciprenaline may decrease the antihypertensive activities of Dexniguldipine.
Tocopherylquinone Orciprenaline may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Orciprenaline may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Orciprenaline may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Orciprenaline may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Orciprenaline may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Orciprenaline may decrease the antihypertensive activities of Quinaprilat.
Felodipine Orciprenaline may decrease the antihypertensive activities of Felodipine.

Target Protein

Beta-2 adrenergic receptor ADRB2

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 20 • International brands: 1
Produk
  • Alupent
    Aerosol, metered • 0.650 mg/1 • Respiratory (inhalation) • US • Approved
  • Alupent
    Aerosol, metered • 0.650 mg/1 • Respiratory (inhalation) • US • Approved
  • Alupent Aer
    Aerosol • .75 mg • Respiratory (inhalation) • Canada • Approved
  • Alupent Liq 50mg/ml
    Liquid • 50 mg / mL • Respiratory (inhalation) • Canada • Approved
  • Alupent Syr 10mg/5.0ml
    Syrup • 10 mg / 5 mL • Oral • Canada • Approved
  • Alupent Tab 20mg
    Tablet • 20 mg • Oral • Canada • Approved
  • Metaproterenol Sulfate
    Solution • 15 mg/2.5mL • Respiratory (inhalation) • US • Generic • Approved
  • Metaproterenol Sulfate
    Solution • 10 mg/2.5mL • Respiratory (inhalation) • US • Generic • Approved
Menampilkan 8 dari 20 produk.
International Brands
  • Metaprel

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul