A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Duloxetine | The risk or severity of orthostatic hypotension and syncope can be increased when Tolazoline is combined with Duloxetine. |
| Levodopa | The risk or severity of hypotension and orthostatic hypotension can be increased when Tolazoline is combined with Levodopa. |
| Risperidone | Tolazoline may increase the hypotensive activities of Risperidone. |
| Amifostine | Tolazoline may increase the hypotensive activities of Amifostine. |
| Diazoxide | Diazoxide may increase the hypotensive activities of Tolazoline. |
| Methylphenidate | Methylphenidate may decrease the antihypertensive activities of Tolazoline. |
| Dexmethylphenidate | Dexmethylphenidate may decrease the antihypertensive activities of Tolazoline. |
| Obinutuzumab | Tolazoline may increase the hypotensive activities of Obinutuzumab. |
| Pentoxifylline | Pentoxifylline may increase the hypotensive activities of Tolazoline. |
| Rituximab | Tolazoline may increase the hypotensive activities of Rituximab. |
| Yohimbine | Yohimbine may decrease the antihypertensive activities of Tolazoline. |
| Epicaptopril | Epicaptopril may decrease the antihypertensive activities of Tolazoline. |
| Siponimod | Siponimod may decrease the antihypertensive activities of Tolazoline. |
| Valsartan | Tolazoline may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Tolazoline may decrease the antihypertensive activities of Ramipril. |
| Reserpine | Tolazoline may decrease the antihypertensive activities of Reserpine. |
| Torasemide | Tolazoline may decrease the antihypertensive activities of Torasemide. |
| Olmesartan | Tolazoline may decrease the antihypertensive activities of Olmesartan. |
| Chlorthalidone | Tolazoline may decrease the antihypertensive activities of Chlorthalidone. |
| Nitroprusside | Tolazoline may decrease the antihypertensive activities of Nitroprusside. |
| Minoxidil | Tolazoline may decrease the antihypertensive activities of Minoxidil. |
| Fosinopril | Tolazoline may decrease the antihypertensive activities of Fosinopril. |
| Trandolapril | Tolazoline may decrease the antihypertensive activities of Trandolapril. |
| Metolazone | Tolazoline may decrease the antihypertensive activities of Metolazone. |
| Benazepril | Tolazoline may decrease the antihypertensive activities of Benazepril. |
| Enalapril | Tolazoline may decrease the antihypertensive activities of Enalapril. |
| Mecamylamine | Tolazoline may decrease the antihypertensive activities of Mecamylamine. |
| Losartan | Tolazoline may decrease the antihypertensive activities of Losartan. |
| Moexipril | Tolazoline may decrease the antihypertensive activities of Moexipril. |
| Furosemide | Tolazoline may decrease the antihypertensive activities of Furosemide. |
| Eplerenone | Tolazoline may decrease the antihypertensive activities of Eplerenone. |
| Sufentanil | Sufentanil may decrease the antihypertensive activities of Tolazoline. |
| Lisinopril | Tolazoline may decrease the antihypertensive activities of Lisinopril. |
| Nitroglycerin | Tolazoline may decrease the antihypertensive activities of Nitroglycerin. |
| Isoflurane | Isoflurane may decrease the antihypertensive activities of Tolazoline. |
| Perindopril | Tolazoline may decrease the antihypertensive activities of Perindopril. |
| Candesartan cilexetil | Tolazoline may decrease the antihypertensive activities of Candesartan cilexetil. |
| Remikiren | Tolazoline may decrease the antihypertensive activities of Remikiren. |
| Guanadrel | Tolazoline may decrease the antihypertensive activities of Guanadrel. |
| Bosentan | Tolazoline may decrease the antihypertensive activities of Bosentan. |
| Candoxatril | Tolazoline may decrease the antihypertensive activities of Candoxatril. |
| Metyrosine | Tolazoline may decrease the antihypertensive activities of Metyrosine. |
| Cryptenamine | Tolazoline may decrease the antihypertensive activities of Cryptenamine. |
| Fenoldopam | Tolazoline may decrease the antihypertensive activities of Fenoldopam. |
| Eprosartan | Tolazoline may decrease the antihypertensive activities of Eprosartan. |
| Quinapril | Tolazoline may decrease the antihypertensive activities of Quinapril. |
| Omapatrilat | Tolazoline may decrease the antihypertensive activities of Omapatrilat. |
| Telmisartan | Tolazoline may decrease the antihypertensive activities of Telmisartan. |
| Irbesartan | Tolazoline may decrease the antihypertensive activities of Irbesartan. |
| Deserpidine | Tolazoline may decrease the antihypertensive activities of Deserpidine. |
| Pentolinium | Tolazoline may decrease the antihypertensive activities of Pentolinium. |
| Trimethaphan | Tolazoline may decrease the antihypertensive activities of Trimethaphan. |
| Bretylium | Tolazoline may decrease the antihypertensive activities of Bretylium. |
| Guanethidine | Tolazoline may decrease the antihypertensive activities of Guanethidine. |
| Rescinnamine | Tolazoline may decrease the antihypertensive activities of Rescinnamine. |
| Captopril | Tolazoline may decrease the antihypertensive activities of Captopril. |
| Hydralazine | Tolazoline may decrease the antihypertensive activities of Hydralazine. |
| Cilazapril | Tolazoline may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Tolazoline may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Tolazoline may decrease the antihypertensive activities of Spirapril. |
| Tienilic acid | Tolazoline may decrease the antihypertensive activities of Tienilic acid. |
| Debrisoquine | Tolazoline may decrease the antihypertensive activities of Debrisoquine. |
| Sitaxentan | Tolazoline may decrease the antihypertensive activities of Sitaxentan. |
| Ambrisentan | Tolazoline may decrease the antihypertensive activities of Ambrisentan. |
| Diethylnorspermine | Tolazoline may decrease the antihypertensive activities of Diethylnorspermine. |
| Pinacidil | Tolazoline may decrease the antihypertensive activities of Pinacidil. |
| Temocapril | Tolazoline may decrease the antihypertensive activities of Temocapril. |
| Riociguat | Tolazoline may decrease the antihypertensive activities of Riociguat. |
| Macitentan | Tolazoline may decrease the antihypertensive activities of Macitentan. |
| Hexamethonium | Tolazoline may decrease the antihypertensive activities of Hexamethonium. |
| Aliskiren | Tolazoline may decrease the antihypertensive activities of Aliskiren. |
| Rauwolfia serpentina root | Tolazoline may decrease the antihypertensive activities of Rauwolfia serpentina root. |
| Enalaprilat | Tolazoline may decrease the antihypertensive activities of Enalaprilat. |
| Selexipag | Tolazoline may decrease the antihypertensive activities of Selexipag. |
| Angiotensin 1-7 | Tolazoline may decrease the antihypertensive activities of Angiotensin 1-7. |
| Imidapril | Tolazoline may decrease the antihypertensive activities of Imidapril. |
| BQ-123 | Tolazoline may decrease the antihypertensive activities of BQ-123. |
| Cicletanine | Tolazoline may decrease the antihypertensive activities of Cicletanine. |
| Dihydralazine | Tolazoline may decrease the antihypertensive activities of Dihydralazine. |
| Zofenopril | Tolazoline may decrease the antihypertensive activities of Zofenopril. |
| Guanoxan | Tolazoline may decrease the antihypertensive activities of Guanoxan. |
| Delapril | Tolazoline may decrease the antihypertensive activities of Delapril. |
| Vincamine | Tolazoline may decrease the antihypertensive activities of Vincamine. |
| Linsidomine | Tolazoline may decrease the antihypertensive activities of Linsidomine. |
| Guanoxabenz | Tolazoline may decrease the antihypertensive activities of Guanoxabenz. |
| Tolonidine | Tolazoline may decrease the antihypertensive activities of Tolonidine. |
| Endralazine | Tolazoline may decrease the antihypertensive activities of Endralazine. |
| Cadralazine | Tolazoline may decrease the antihypertensive activities of Cadralazine. |
| Bietaserpine | Tolazoline may decrease the antihypertensive activities of Bietaserpine. |
| Guanazodine | Tolazoline may decrease the antihypertensive activities of Guanazodine. |
| Methoserpidine | Tolazoline may decrease the antihypertensive activities of Methoserpidine. |
| Guanoclor | Tolazoline may decrease the antihypertensive activities of Guanoclor. |
| Muzolimine | Tolazoline may decrease the antihypertensive activities of Muzolimine. |
| Xipamide | Tolazoline may decrease the antihypertensive activities of Xipamide. |
| Candesartan | Tolazoline may decrease the antihypertensive activities of Candesartan. |
| Tocopherylquinone | Tolazoline may decrease the antihypertensive activities of Tocopherylquinone. |
| Benazeprilat | Tolazoline may decrease the antihypertensive activities of Benazeprilat. |
| Fosinoprilat | Tolazoline may decrease the antihypertensive activities of Fosinoprilat. |
| Ramiprilat | Tolazoline may decrease the antihypertensive activities of Ramiprilat. |
| Perindoprilat | Tolazoline may decrease the antihypertensive activities of Perindoprilat. |