Propantheline

DB00782

small molecule approved

Deskripsi

A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.

Struktur Molekul 2D

Berat 368.4892
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Approximately 70% of the dose is excreted in the urine, mostly as metabolites.

Interaksi Makanan

1 Data
  • 1. Take before a meal. Take before a meal. Propantheline bromide should be taken 15 to 30 minutes before meals.

Interaksi Obat

1147 Data
Aclidinium The risk or severity of adverse effects can be increased when Propantheline is combined with Aclidinium.
Mianserin Mianserin may increase the anticholinergic activities of Propantheline.
Mirabegron The risk or severity of urinary retention can be increased when Propantheline is combined with Mirabegron.
Pramlintide The risk or severity of reduced gastrointestinal motility can be increased when Pramlintide is combined with Propantheline.
Secretin porcine The therapeutic efficacy of Secretin porcine can be decreased when used in combination with Propantheline.
Tiotropium The risk or severity of adverse effects can be increased when Propantheline is combined with Tiotropium.
Topiramate The risk or severity of hyperthermia and oligohydrosis can be increased when Propantheline is combined with Topiramate.
Umeclidinium The risk or severity of adverse effects can be increased when Propantheline is combined with Umeclidinium.
Glycopyrronium The risk or severity of adverse effects can be increased when Propantheline is combined with Glycopyrronium.
Botulinum toxin type A The risk or severity of adverse effects can be increased when Propantheline is combined with Botulinum toxin type A.
Glucagon Propantheline may increase the gastrointestinal motility reducing activities of Glucagon.
Sulpiride Propantheline may increase the anticholinergic activities of Sulpiride.
Botulinum toxin type B The risk or severity of adverse effects can be increased when Propantheline is combined with Botulinum toxin type B.
Eluxadoline The risk or severity of constipation can be increased when Propantheline is combined with Eluxadoline.
Ramosetron The risk or severity of constipation can be increased when Propantheline is combined with Ramosetron.
Naltrexone The risk or severity of adverse effects can be increased when Propantheline is combined with Naltrexone.
Bezitramide The risk or severity of adverse effects can be increased when Propantheline is combined with Bezitramide.
Tramadol The risk or severity of adverse effects can be increased when Propantheline is combined with Tramadol.
Morphine The risk or severity of adverse effects can be increased when Propantheline is combined with Morphine.
Hydromorphone The risk or severity of adverse effects can be increased when Propantheline is combined with Hydromorphone.
Methadone The risk or severity of adverse effects can be increased when Propantheline is combined with Methadone.
Oxycodone The risk or severity of adverse effects can be increased when Propantheline is combined with Oxycodone.
Butorphanol The risk or severity of adverse effects can be increased when Propantheline is combined with Butorphanol.
Dextropropoxyphene The risk or severity of adverse effects can be increased when Propantheline is combined with Dextropropoxyphene.
Pentazocine The risk or severity of adverse effects can be increased when Propantheline is combined with Pentazocine.
Sufentanil The risk or severity of adverse effects can be increased when Propantheline is combined with Sufentanil.
Alfentanil The risk or severity of adverse effects can be increased when Propantheline is combined with Alfentanil.
Nalbuphine The risk or severity of adverse effects can be increased when Propantheline is combined with Nalbuphine.
Levorphanol The risk or severity of adverse effects can be increased when Propantheline is combined with Levorphanol.
Remifentanil The risk or severity of adverse effects can be increased when Propantheline is combined with Remifentanil.
Buprenorphine The risk or severity of adverse effects can be increased when Propantheline is combined with Buprenorphine.
Hydrocodone The risk or severity of adverse effects can be increased when Propantheline is combined with Hydrocodone.
Diphenoxylate The risk or severity of adverse effects can be increased when Propantheline is combined with Diphenoxylate.
Oxymorphone The risk or severity of adverse effects can be increased when Propantheline is combined with Oxymorphone.
Dezocine The risk or severity of adverse effects can be increased when Propantheline is combined with Dezocine.
Levacetylmethadol The risk or severity of adverse effects can be increased when Propantheline is combined with Levacetylmethadol.
Methadyl acetate The risk or severity of adverse effects can be increased when Propantheline is combined with Methadyl acetate.
Dihydroetorphine The risk or severity of adverse effects can be increased when Propantheline is combined with Dihydroetorphine.
Diamorphine The risk or severity of adverse effects can be increased when Propantheline is combined with Diamorphine.
Ethylmorphine The risk or severity of adverse effects can be increased when Propantheline is combined with Ethylmorphine.
Etorphine The risk or severity of adverse effects can be increased when Propantheline is combined with Etorphine.
Dextromoramide The risk or severity of adverse effects can be increased when Propantheline is combined with Dextromoramide.
Desomorphine The risk or severity of adverse effects can be increased when Propantheline is combined with Desomorphine.
Carfentanil The risk or severity of adverse effects can be increased when Propantheline is combined with Carfentanil.
Dihydrocodeine The risk or severity of adverse effects can be increased when Propantheline is combined with Dihydrocodeine.
Alphacetylmethadol The risk or severity of adverse effects can be increased when Propantheline is combined with Alphacetylmethadol.
Dihydromorphine The risk or severity of adverse effects can be increased when Propantheline is combined with Dihydromorphine.
Tapentadol The risk or severity of urinary retention and constipation can be increased when Propantheline is combined with Tapentadol.
Ketobemidone The risk or severity of adverse effects can be increased when Propantheline is combined with Ketobemidone.
DPDPE The risk or severity of adverse effects can be increased when Propantheline is combined with DPDPE.
Lofentanil The risk or severity of adverse effects can be increased when Propantheline is combined with Lofentanil.
Opium The risk or severity of adverse effects can be increased when Propantheline is combined with Opium.
Normethadone The risk or severity of adverse effects can be increased when Propantheline is combined with Normethadone.
Piritramide The risk or severity of adverse effects can be increased when Propantheline is combined with Piritramide.
Alphaprodine The risk or severity of adverse effects can be increased when Propantheline is combined with Alphaprodine.
Nicomorphine The risk or severity of adverse effects can be increased when Propantheline is combined with Nicomorphine.
Meptazinol The risk or severity of adverse effects can be increased when Propantheline is combined with Meptazinol.
Phenoperidine The risk or severity of adverse effects can be increased when Propantheline is combined with Phenoperidine.
Phenazocine The risk or severity of adverse effects can be increased when Propantheline is combined with Phenazocine.
Tilidine The risk or severity of adverse effects can be increased when Propantheline is combined with Tilidine.
Carfentanil, C-11 The risk or severity of adverse effects can be increased when Propantheline is combined with Carfentanil, C-11.
Codeine The risk or severity of adverse effects can be increased when Propantheline is combined with Codeine.
Meperidine The risk or severity of adverse effects can be increased when Propantheline is combined with Meperidine.
Fentanyl The risk or severity of adverse effects can be increased when Propantheline is combined with Fentanyl.
Benzhydrocodone The risk or severity of adverse effects can be increased when Propantheline is combined with Benzhydrocodone.
Naloxegol The risk or severity of adverse effects can be increased when Propantheline is combined with Naloxegol.
Trospium The risk or severity of adverse effects can be increased when Trospium is combined with Propantheline.
Oxyphenonium The risk or severity of adverse effects can be increased when Oxyphenonium is combined with Propantheline.
Metixene The risk or severity of adverse effects can be increased when Metixene is combined with Propantheline.
Terfenadine The risk or severity of adverse effects can be increased when Terfenadine is combined with Propantheline.
Buclizine The risk or severity of adverse effects can be increased when Buclizine is combined with Propantheline.
Trihexyphenidyl The risk or severity of adverse effects can be increased when Trihexyphenidyl is combined with Propantheline.
Oxyphencyclimine The risk or severity of adverse effects can be increased when Oxyphencyclimine is combined with Propantheline.
Procyclidine The risk or severity of adverse effects can be increased when Procyclidine is combined with Propantheline.
Hyoscyamine The risk or severity of adverse effects can be increased when Hyoscyamine is combined with Propantheline.
Methscopolamine bromide The risk or severity of adverse effects can be increased when Methscopolamine bromide is combined with Propantheline.
Darifenacin The risk or severity of adverse effects can be increased when Darifenacin is combined with Propantheline.
Tridihexethyl The risk or severity of adverse effects can be increased when Tridihexethyl is combined with Propantheline.
Anisotropine methylbromide The risk or severity of adverse effects can be increased when Anisotropine methylbromide is combined with Propantheline.
Atropine The risk or severity of adverse effects can be increased when Atropine is combined with Propantheline.
Nicardipine The risk or severity of adverse effects can be increased when Nicardipine is combined with Propantheline.
Pirenzepine The risk or severity of adverse effects can be increased when Pirenzepine is combined with Propantheline.
Homatropine methylbromide The risk or severity of adverse effects can be increased when Homatropine methylbromide is combined with Propantheline.
Benzquinamide The risk or severity of adverse effects can be increased when Benzquinamide is combined with Propantheline.
Tropicamide The risk or severity of adverse effects can be increased when Propantheline is combined with Tropicamide.
Cocaine The risk or severity of adverse effects can be increased when Propantheline is combined with Cocaine.
Methantheline The risk or severity of adverse effects can be increased when Propantheline is combined with Methantheline.
Cycrimine The risk or severity of adverse effects can be increased when Propantheline is combined with Cycrimine.
Cyclopentolate The risk or severity of adverse effects can be increased when Propantheline is combined with Cyclopentolate.
Oxybutynin The risk or severity of adverse effects can be increased when Propantheline is combined with Oxybutynin.
Pentolinium The risk or severity of adverse effects can be increased when Propantheline is combined with Pentolinium.
Trimethaphan The risk or severity of adverse effects can be increased when Propantheline is combined with Trimethaphan.
Diphenidol The risk or severity of adverse effects can be increased when Propantheline is combined with Diphenidol.
Fenoterol The risk or severity of adverse effects can be increased when Propantheline is combined with Fenoterol.
Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione The risk or severity of adverse effects can be increased when Propantheline is combined with Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione.
Solifenacin The risk or severity of adverse effects can be increased when Propantheline is combined with Solifenacin.
Isopropamide The risk or severity of adverse effects can be increased when Propantheline is combined with Isopropamide.
Mepenzolate The risk or severity of adverse effects can be increased when Propantheline is combined with Mepenzolate.
Hexocyclium The risk or severity of adverse effects can be increased when Propantheline is combined with Hexocyclium.
Dimetindene The risk or severity of adverse effects can be increased when Propantheline is combined with Dimetindene.

Target Protein

Muscarinic acetylcholine receptor M1 CHRM1

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 6 • International brands: 7
Produk
  • Pro-Banthine
    Tablet • 15 mg/1 • Oral • US • Approved
  • Pro-Banthine
    Tablet • 7.5 mg/1 • Oral • US • Approved
  • Pro-banthine Tablets 15mg
    Tablet • 15 mg • Oral • Canada • Approved
  • Pro-banthine Tablets 7.5 mg
    Tablet • 7.5 mg • Oral • Canada • Approved
  • Propanthel Tab 15mg
    Tablet • 15 mg • Oral • Canada • Approved
  • Propantheline Bromide
    Tablet, film coated • 15 mg/1 • Oral • US • Generic • Approved
International Brands
  • Ercoril — Medic
  • Methaphyllin — Sannova
  • Pro Banthine — Pfizer
  • Prokind — Beacon
  • Propanline — Chin Teng
  • Propantheline — Shou Chan
  • Spastheline — Sun

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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