Peringatan Keamanan

Side effects include burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, miliaria.

Hydrocortamate

DB00769

small molecule approved

Deskripsi

Hydrocortamate is a synthetic glucocorticoid used for its anti-inflammatory or immunosuppressive properties to treat inflammation due to corticosteroid-responsive dermatoses. Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger a variety of important cardiovascular, metabolic, immunologic and homeostatic effects.

Struktur Molekul 2D

Berat 475.6175
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Primarily hepatic via CYP3A4

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

215 Data
Aripiprazole The metabolism of Aripiprazole can be increased when combined with Hydrocortamate.
Aripiprazole lauroxil The metabolism of Aripiprazole lauroxil can be increased when combined with Hydrocortamate.
Ifosfamide The metabolism of Ifosfamide can be increased when combined with Hydrocortamate.
Perampanel The metabolism of Perampanel can be increased when combined with Hydrocortamate.
Warfarin The metabolism of Warfarin can be increased when combined with Hydrocortamate.
Acenocoumarol The metabolism of Acenocoumarol can be increased when combined with Hydrocortamate.
(R)-warfarin The metabolism of (R)-warfarin can be increased when combined with Hydrocortamate.
R,S-Warfarin alcohol The metabolism of R,S-Warfarin alcohol can be increased when combined with Hydrocortamate.
S,R-Warfarin alcohol The metabolism of S,R-Warfarin alcohol can be increased when combined with Hydrocortamate.
(S)-Warfarin The metabolism of (S)-Warfarin can be increased when combined with Hydrocortamate.
Erlotinib The serum concentration of Erlotinib can be decreased when it is combined with Hydrocortamate.
Segesterone acetate The metabolism of Segesterone acetate can be increased when combined with Hydrocortamate.
Diethylstilbestrol The metabolism of Diethylstilbestrol can be increased when combined with Hydrocortamate.
Etonogestrel The metabolism of Etonogestrel can be increased when combined with Hydrocortamate.
Desogestrel The metabolism of Desogestrel can be increased when combined with Hydrocortamate.
Megestrol acetate The metabolism of Megestrol acetate can be increased when combined with Hydrocortamate.
Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Hydrocortamate.
Progesterone The metabolism of Progesterone can be increased when combined with Hydrocortamate.
Medroxyprogesterone acetate The metabolism of Medroxyprogesterone acetate can be increased when combined with Hydrocortamate.
Norethisterone The metabolism of Norethisterone can be increased when combined with Hydrocortamate.
Estradiol The metabolism of Estradiol can be increased when combined with Hydrocortamate.
Ethynodiol diacetate The metabolism of Ethynodiol diacetate can be increased when combined with Hydrocortamate.
Mifepristone The metabolism of Mifepristone can be increased when combined with Hydrocortamate.
Norgestimate The metabolism of Norgestimate can be increased when combined with Hydrocortamate.
Ethinylestradiol The metabolism of Ethinylestradiol can be increased when combined with Hydrocortamate.
Mestranol The metabolism of Mestranol can be increased when combined with Hydrocortamate.
Drospirenone The metabolism of Drospirenone can be increased when combined with Hydrocortamate.
Estrone sulfate The metabolism of Estrone sulfate can be increased when combined with Hydrocortamate.
Octylphenoxy polyethoxyethanol The metabolism of Octylphenoxy polyethoxyethanol can be increased when combined with Hydrocortamate.
Cyproterone acetate The metabolism of Cyproterone acetate can be increased when combined with Hydrocortamate.
Trestolone The metabolism of Trestolone can be increased when combined with Hydrocortamate.
Norelgestromin The metabolism of Norelgestromin can be increased when combined with Hydrocortamate.
Gestodene The metabolism of Gestodene can be increased when combined with Hydrocortamate.
Hydroxyprogesterone caproate The metabolism of Hydroxyprogesterone caproate can be increased when combined with Hydrocortamate.
Dienogest The metabolism of Dienogest can be increased when combined with Hydrocortamate.
Norethynodrel The metabolism of Norethynodrel can be increased when combined with Hydrocortamate.
Norgestrel The metabolism of Norgestrel can be increased when combined with Hydrocortamate.
Cloprostenol The metabolism of Cloprostenol can be increased when combined with Hydrocortamate.
Gestrinone The metabolism of Gestrinone can be increased when combined with Hydrocortamate.
Nomegestrol The metabolism of Nomegestrol can be increased when combined with Hydrocortamate.
Lynestrenol The metabolism of Lynestrenol can be increased when combined with Hydrocortamate.
Gossypol The metabolism of Gossypol can be increased when combined with Hydrocortamate.
Ormeloxifene The metabolism of Ormeloxifene can be increased when combined with Hydrocortamate.
Chlormadinone The metabolism of Chlormadinone can be increased when combined with Hydrocortamate.
Norgestrienone The metabolism of Norgestrienone can be increased when combined with Hydrocortamate.
Quingestanol The metabolism of Quingestanol can be increased when combined with Hydrocortamate.
Demegestone The metabolism of Demegestone can be increased when combined with Hydrocortamate.
Etynodiol The metabolism of Etynodiol can be increased when combined with Hydrocortamate.
Testosterone enanthate The metabolism of Testosterone enanthate can be increased when combined with Hydrocortamate.
Estradiol benzoate The metabolism of Estradiol benzoate can be increased when combined with Hydrocortamate.
Estradiol cypionate The metabolism of Estradiol cypionate can be increased when combined with Hydrocortamate.
Estradiol valerate The metabolism of Estradiol valerate can be increased when combined with Hydrocortamate.
Nomegestrol acetate The metabolism of Nomegestrol acetate can be increased when combined with Hydrocortamate.
Norethindrone enanthate The metabolism of Norethindrone enanthate can be increased when combined with Hydrocortamate.
Ulipristal The metabolism of Ulipristal can be increased when combined with Hydrocortamate.
Azithromycin The metabolism of Azithromycin can be increased when combined with Hydrocortamate.
Ziprasidone The metabolism of Ziprasidone can be increased when combined with Hydrocortamate.
Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Hydrocortamate.
Albendazole The metabolism of Albendazole can be increased when combined with Hydrocortamate.
Cephalexin The metabolism of Cephalexin can be increased when combined with Hydrocortamate.
Doxazosin The metabolism of Doxazosin can be increased when combined with Hydrocortamate.
Fenofibrate The metabolism of Fenofibrate can be increased when combined with Hydrocortamate.
Atazanavir The metabolism of Atazanavir can be increased when combined with Hydrocortamate.
Rosuvastatin The metabolism of Rosuvastatin can be increased when combined with Hydrocortamate.
Allylestrenol The metabolism of Allylestrenol can be increased when combined with Hydrocortamate.
Zuclopenthixol The metabolism of Zuclopenthixol can be increased when combined with Hydrocortamate.
Roflumilast The metabolism of Roflumilast can be increased when combined with Hydrocortamate.
Lacosamide The metabolism of Lacosamide can be increased when combined with Hydrocortamate.
Linagliptin The metabolism of Linagliptin can be increased when combined with Hydrocortamate.
Vorapaxar The metabolism of Vorapaxar can be increased when combined with Hydrocortamate.
Suvorexant The metabolism of Suvorexant can be increased when combined with Hydrocortamate.
Netupitant The metabolism of Netupitant can be increased when combined with Hydrocortamate.
Tasimelteon The metabolism of Tasimelteon can be increased when combined with Hydrocortamate.
Nintedanib The metabolism of Nintedanib can be increased when combined with Hydrocortamate.
Tenofovir alafenamide The metabolism of Tenofovir alafenamide can be increased when combined with Hydrocortamate.
Dihydroergocornine The metabolism of Dihydroergocornine can be increased when combined with Hydrocortamate.
Duvelisib The metabolism of Duvelisib can be increased when combined with Hydrocortamate.
Gilteritinib The metabolism of Gilteritinib can be increased when combined with Hydrocortamate.
9-aminocamptothecin The metabolism of 9-aminocamptothecin can be increased when combined with Hydrocortamate.
Methylprednisone The metabolism of Methylprednisone can be increased when combined with Hydrocortamate.
Dihydroergocristine The metabolism of Dihydroergocristine can be increased when combined with Hydrocortamate.
Dihydroergocryptine The metabolism of Dihydroergocryptine can be increased when combined with Hydrocortamate.
Medical Cannabis The metabolism of Medical Cannabis can be increased when combined with Hydrocortamate.
Elexacaftor The metabolism of Elexacaftor can be increased when combined with Hydrocortamate.
Tazemetostat The metabolism of Tazemetostat can be increased when combined with Hydrocortamate.
Fosaprepitant The metabolism of Fosaprepitant can be increased when combined with Hydrocortamate.
Lefamulin The metabolism of Lefamulin can be increased when combined with Hydrocortamate.
Methysergide The metabolism of Methysergide can be increased when combined with Hydrocortamate.
Meperidine The metabolism of Meperidine can be increased when combined with Hydrocortamate.
Ebastine The metabolism of Ebastine can be increased when combined with Hydrocortamate.
Terfenadine The metabolism of Terfenadine can be increased when combined with Hydrocortamate.
Cisapride The metabolism of Cisapride can be increased when combined with Hydrocortamate.
Isavuconazole The metabolism of Isavuconazole can be increased when combined with Hydrocortamate.
Pretomanid The metabolism of Pretomanid can be increased when combined with Hydrocortamate.
Pimavanserin The metabolism of Pimavanserin can be increased when combined with Hydrocortamate.
Estetrol The metabolism of Estetrol can be increased when combined with Hydrocortamate.
Infigratinib The metabolism of Infigratinib can be increased when combined with Hydrocortamate.
Cyclosporine The metabolism of Cyclosporine can be increased when combined with Hydrocortamate.
Dofetilide The metabolism of Dofetilide can be increased when combined with Hydrocortamate.
Theophylline The metabolism of Theophylline can be increased when combined with Hydrocortamate.

Target Protein

Glucocorticoid receptor NR3C1

Referensi & Sumber

Synthesis reference: British Patent 879,208; October 4, 1961.

Contoh Produk & Brand

Produk: 0 • International brands: 4
International Brands
  • Etacort — Angelini
  • Magnacort — Pfizer
  • Ulcort
  • Ulcort top

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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