Prilocaine

DB00750

small molecule approved

Deskripsi

A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)

Struktur Molekul 2D

Berat 220.3107
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Prilocaine is metabolized in both the liver and the kidney and excreted via the kidney.

Interaksi Makanan

1 Data
  • 1. Take separate from meals. This is only required when prilocaine is used in the mouth, as it may cause numbness, which can cause bite injury when eating.

Interaksi Obat

1605 Data
Buprenorphine Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Prilocaine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Prilocaine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Prilocaine.
Hydrocodone Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Prilocaine.
Magnesium sulfate The therapeutic efficacy of Prilocaine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Prilocaine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Prilocaine.
Mirtazapine Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Prilocaine.
Orphenadrine Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Prilocaine.
Pramipexole Prilocaine may increase the sedative activities of Pramipexole.
Ropinirole Prilocaine may increase the sedative activities of Ropinirole.
Rotigotine Prilocaine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Prilocaine.
Sodium oxybate The risk or severity of CNS depression can be increased when Prilocaine is combined with Sodium oxybate.
Suvorexant Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Prilocaine.
Thalidomide Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Butalbital The risk or severity of methemoglobinemia can be increased when Butalbital is combined with Prilocaine.
Phenytoin The risk or severity of methemoglobinemia can be increased when Phenytoin is combined with Prilocaine.
Acetaminophen The risk or severity of methemoglobinemia can be increased when Acetaminophen is combined with Prilocaine.
Nitroprusside The risk or severity of methemoglobinemia can be increased when Nitroprusside is combined with Prilocaine.
Sulfadiazine The risk or severity of methemoglobinemia can be increased when Sulfadiazine is combined with Prilocaine.
Nitric Oxide The risk or severity of methemoglobinemia can be increased when Nitric Oxide is combined with Prilocaine.
Quinine The risk or severity of methemoglobinemia can be increased when Quinine is combined with Prilocaine.
Celecoxib The risk or severity of methemoglobinemia can be increased when Celecoxib is combined with Prilocaine.
Flutamide The risk or severity of methemoglobinemia can be increased when Flutamide is combined with Prilocaine.
Chloroquine The risk or severity of methemoglobinemia can be increased when Chloroquine is combined with Prilocaine.
Nitrofurantoin The risk or severity of methemoglobinemia can be increased when Nitrofurantoin is combined with Prilocaine.
Nitroglycerin The risk or severity of methemoglobinemia can be increased when Nitroglycerin is combined with Prilocaine.
Isosorbide dinitrate The risk or severity of methemoglobinemia can be increased when Isosorbide dinitrate is combined with Prilocaine.
Sulfamethoxazole The risk or severity of methemoglobinemia can be increased when Sulfamethoxazole is combined with Prilocaine.
Isosorbide mononitrate The risk or severity of methemoglobinemia can be increased when Isosorbide mononitrate is combined with Prilocaine.
Benzocaine The risk or severity of methemoglobinemia can be increased when Benzocaine is combined with Prilocaine.
Primaquine The risk or severity of methemoglobinemia can be increased when Primaquine is combined with Prilocaine.
Phenobarbital The risk or severity of methemoglobinemia can be increased when Phenobarbital is combined with Prilocaine.
Zopiclone The risk or severity of methemoglobinemia can be increased when Zopiclone is combined with Prilocaine.
Metoclopramide The risk or severity of methemoglobinemia can be increased when Metoclopramide is combined with Prilocaine.
Antipyrine The risk or severity of methemoglobinemia can be increased when Antipyrine is combined with Prilocaine.
Phenazopyridine The risk or severity of methemoglobinemia can be increased when Phenazopyridine is combined with Prilocaine.
Amyl Nitrite The risk or severity of methemoglobinemia can be increased when Amyl Nitrite is combined with Prilocaine.
Isometheptene The risk or severity of methemoglobinemia can be increased when Isometheptene is combined with Prilocaine.
Mafenide The risk or severity of methemoglobinemia can be increased when Mafenide is combined with Prilocaine.
Nitrous oxide The risk or severity of methemoglobinemia can be increased when Nitrous oxide is combined with Prilocaine.
Cyclophosphamide The risk or severity of methemoglobinemia can be increased when Cyclophosphamide is combined with Prilocaine.
Ifosfamide The risk or severity of methemoglobinemia can be increased when Ifosfamide is combined with Prilocaine.
Sulfasalazine The risk or severity of methemoglobinemia can be increased when Sulfasalazine is combined with Prilocaine.
Sulfanilamide The risk or severity of methemoglobinemia can be increased when Sulfanilamide is combined with Prilocaine.
Sulfapyridine The risk or severity of methemoglobinemia can be increased when Sulfapyridine is combined with Prilocaine.
Valproic acid The risk or severity of methemoglobinemia can be increased when Valproic acid is combined with Prilocaine.
Bupivacaine The risk or severity of methemoglobinemia can be increased when Bupivacaine is combined with Prilocaine.
Procaine The risk or severity of methemoglobinemia can be increased when Procaine is combined with Prilocaine.
Mepivacaine The risk or severity of methemoglobinemia can be increased when Mepivacaine is combined with Prilocaine.
Articaine The risk or severity of methemoglobinemia can be increased when Articaine is combined with Prilocaine.
Tetracaine The risk or severity of methemoglobinemia can be increased when Tetracaine is combined with Prilocaine.
Ropivacaine The risk or severity of methemoglobinemia can be increased when Ropivacaine is combined with Prilocaine.
Rasburicase The risk or severity of methemoglobinemia can be increased when Rasburicase is combined with Prilocaine.
Aminosalicylic acid The risk or severity of methemoglobinemia can be increased when Aminosalicylic acid is combined with Prilocaine.
Hydroxyurea The risk or severity of methemoglobinemia can be increased when Hydroxyurea is combined with Prilocaine.
Hyaluronidase (ovine) Hyaluronidase (ovine) can cause an increase in the absorption of Prilocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Hyaluronidase (human recombinant) Hyaluronidase (human recombinant) can cause an increase in the absorption of Prilocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Hyaluronidase Hyaluronidase can cause an increase in the absorption of Prilocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Prilocaine.
Ethanol Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Prilocaine.
Fluvoxamine The risk or severity of adverse effects can be increased when Prilocaine is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Prilocaine is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Prilocaine is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Prilocaine is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Prilocaine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Prilocaine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Prilocaine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Prilocaine is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Prilocaine is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when Prilocaine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Prilocaine is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Prilocaine is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Prilocaine is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Prilocaine is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Prilocaine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Prilocaine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Prilocaine is combined with Alaproclate.
Dapsone The risk or severity of methemoglobinemia can be increased when Dapsone is combined with Prilocaine.
Technetium Tc-99m tilmanocept Prilocaine may decrease effectiveness of Technetium Tc-99m tilmanocept as a diagnostic agent.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Prilocaine.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with Prilocaine.
Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with Prilocaine.
Promazine The risk or severity of CNS depression can be increased when Promazine is combined with Prilocaine.
Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Prilocaine.
Imipramine The risk or severity of CNS depression can be increased when Imipramine is combined with Prilocaine.
Chlorpromazine The risk or severity of CNS depression can be increased when Chlorpromazine is combined with Prilocaine.
Gallamine triethiodide The risk or severity of CNS depression can be increased when Gallamine triethiodide is combined with Prilocaine.
Triflupromazine The risk or severity of CNS depression can be increased when Triflupromazine is combined with Prilocaine.

Target Protein

Sodium channel protein type 5 subunit alpha SCN5A

Referensi & Sumber

Contoh Produk & Brand

Produk: 141 • International brands: 4
Produk
  • 4% Citanest Forte Dental With Epinephrine 1:200,000
    Solution • - • Infiltration • Canada • Approved
  • 4% Citanest Plain Dental
    Solution • 40 mg / mL • Infiltration • Canada • Approved
  • ACAT SUK Kit (Accelerated COVID-19 Antibody Test Single Use Kit)
    Kit • - • Topical • US
  • ACT Kit (Accelerated COVID-19 Test Kit)
    Kit • - • Topical • US
  • AgonEaze
    Kit • - • Topical • US
  • AgonEaze
    Kit • - • Topical • US
  • Anodyne LPT
    Kit • - • Topical • US • Generic • Approved
  • Aprizio Pak
    Cream; Kit • - • Topical • US
Menampilkan 8 dari 141 produk.
International Brands
  • Citanest — AstraZeneca
  • Prilotekal — Goldshield
  • Takipril — Meduna
  • Xylonest — AstraZeneca

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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