Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of Hetacillin results from the inhibition of cell wall synthesis and is mediated through Hetacillin binding to penicillin binding proteins (PBPs). Hetacillin has been withdrawn from the market since it has been discovered that it has no therapeutic advantage compared to non-ester derivatives like ampicillin.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Methotrexate | The excretion of Methotrexate can be decreased when combined with Hetacillin. |
| Probenecid | The excretion of Hetacillin can be decreased when combined with Probenecid. |
| Doxycycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Doxycycline. |
| Lymecycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Lymecycline. |
| Clomocycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Clomocycline. |
| Tigecycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Tigecycline. |
| Oxytetracycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Oxytetracycline. |
| Demeclocycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Demeclocycline. |
| Tetracycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Tetracycline. |
| Metacycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Metacycline. |
| Minocycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Minocycline. |
| Rolitetracycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Rolitetracycline. |
| Sarecycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Sarecycline. |
| Eravacycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Eravacycline. |
| Omadacycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Omadacycline. |
| Penimepicycline | The therapeutic efficacy of Hetacillin can be decreased when used in combination with Penimepicycline. |
| Mycophenolate mofetil | The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Hetacillin. |
| Mycophenolic acid | The serum concentration of Mycophenolic acid can be decreased when it is combined with Hetacillin. |
| Picosulfuric acid | The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Hetacillin. |
| Diethylstilbestrol | The therapeutic efficacy of Diethylstilbestrol can be decreased when used in combination with Hetacillin. |
| Etonogestrel | The therapeutic efficacy of Etonogestrel can be decreased when used in combination with Hetacillin. |
| Desogestrel | The therapeutic efficacy of Desogestrel can be decreased when used in combination with Hetacillin. |
| Megestrol acetate | The therapeutic efficacy of Megestrol acetate can be decreased when used in combination with Hetacillin. |
| Levonorgestrel | The therapeutic efficacy of Levonorgestrel can be decreased when used in combination with Hetacillin. |
| Progesterone | The therapeutic efficacy of Progesterone can be decreased when used in combination with Hetacillin. |
| Medroxyprogesterone acetate | The therapeutic efficacy of Medroxyprogesterone acetate can be decreased when used in combination with Hetacillin. |
| Norethisterone | The therapeutic efficacy of Norethisterone can be decreased when used in combination with Hetacillin. |
| Estradiol | The therapeutic efficacy of Estradiol can be decreased when used in combination with Hetacillin. |
| Ethynodiol diacetate | The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Hetacillin. |
| Mifepristone | The therapeutic efficacy of Mifepristone can be decreased when used in combination with Hetacillin. |
| Norgestimate | The therapeutic efficacy of Norgestimate can be decreased when used in combination with Hetacillin. |
| Ethinylestradiol | The therapeutic efficacy of Ethinylestradiol can be decreased when used in combination with Hetacillin. |
| Mestranol | The therapeutic efficacy of Mestranol can be decreased when used in combination with Hetacillin. |
| Drospirenone | The therapeutic efficacy of Drospirenone can be decreased when used in combination with Hetacillin. |
| Estrone sulfate | The therapeutic efficacy of Estrone sulfate can be decreased when used in combination with Hetacillin. |
| Octylphenoxy polyethoxyethanol | The therapeutic efficacy of Octylphenoxy polyethoxyethanol can be decreased when used in combination with Hetacillin. |
| Cyproterone acetate | The therapeutic efficacy of Cyproterone acetate can be decreased when used in combination with Hetacillin. |
| Trestolone | The therapeutic efficacy of Trestolone can be decreased when used in combination with Hetacillin. |
| Norelgestromin | The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Hetacillin. |
| Gestodene | The therapeutic efficacy of Gestodene can be decreased when used in combination with Hetacillin. |
| Hydroxyprogesterone caproate | The therapeutic efficacy of Hydroxyprogesterone caproate can be decreased when used in combination with Hetacillin. |
| Ulipristal | The therapeutic efficacy of Ulipristal can be decreased when used in combination with Hetacillin. |
| Dienogest | The therapeutic efficacy of Dienogest can be decreased when used in combination with Hetacillin. |
| Norethynodrel | The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Hetacillin. |
| Norgestrel | The therapeutic efficacy of Norgestrel can be decreased when used in combination with Hetacillin. |
| Cloprostenol | The therapeutic efficacy of Cloprostenol can be decreased when used in combination with Hetacillin. |
| Gestrinone | The therapeutic efficacy of Gestrinone can be decreased when used in combination with Hetacillin. |
| Nomegestrol | The therapeutic efficacy of Nomegestrol can be decreased when used in combination with Hetacillin. |
| Lynestrenol | The therapeutic efficacy of Lynestrenol can be decreased when used in combination with Hetacillin. |
| Gossypol | The therapeutic efficacy of Gossypol can be decreased when used in combination with Hetacillin. |
| Ormeloxifene | The therapeutic efficacy of Ormeloxifene can be decreased when used in combination with Hetacillin. |
| Chlormadinone | The therapeutic efficacy of Chlormadinone can be decreased when used in combination with Hetacillin. |
| Norgestrienone | The therapeutic efficacy of Norgestrienone can be decreased when used in combination with Hetacillin. |
| Quingestanol | The therapeutic efficacy of Quingestanol can be decreased when used in combination with Hetacillin. |
| Demegestone | The therapeutic efficacy of Demegestone can be decreased when used in combination with Hetacillin. |
| Etynodiol | The therapeutic efficacy of Etynodiol can be decreased when used in combination with Hetacillin. |
| Testosterone enanthate | The therapeutic efficacy of Testosterone enanthate can be decreased when used in combination with Hetacillin. |
| Estradiol benzoate | The therapeutic efficacy of Estradiol benzoate can be decreased when used in combination with Hetacillin. |
| Estradiol cypionate | The therapeutic efficacy of Estradiol cypionate can be decreased when used in combination with Hetacillin. |
| Estradiol valerate | The therapeutic efficacy of Estradiol valerate can be decreased when used in combination with Hetacillin. |
| Nomegestrol acetate | The therapeutic efficacy of Nomegestrol acetate can be decreased when used in combination with Hetacillin. |
| Norethindrone enanthate | The therapeutic efficacy of Norethindrone enanthate can be decreased when used in combination with Hetacillin. |
| Capreomycin | The serum concentration of Capreomycin can be decreased when it is combined with Hetacillin. |
| Framycetin | The serum concentration of Framycetin can be decreased when it is combined with Hetacillin. |
| Amikacin | The serum concentration of Amikacin can be decreased when it is combined with Hetacillin. |
| Tobramycin | The serum concentration of Tobramycin can be decreased when it is combined with Hetacillin. |
| Gentamicin | The serum concentration of Gentamicin can be decreased when it is combined with Hetacillin. |
| Netilmicin | The serum concentration of Netilmicin can be decreased when it is combined with Hetacillin. |
| Neomycin | The serum concentration of Neomycin can be decreased when it is combined with Hetacillin. |
| Streptomycin | The serum concentration of Streptomycin can be decreased when it is combined with Hetacillin. |
| Kanamycin | The serum concentration of Kanamycin can be decreased when it is combined with Hetacillin. |
| Paromomycin | The serum concentration of Paromomycin can be decreased when it is combined with Hetacillin. |
| Ribostamycin | The serum concentration of Ribostamycin can be decreased when it is combined with Hetacillin. |
| Geneticin | The serum concentration of Geneticin can be decreased when it is combined with Hetacillin. |
| Apramycin | The serum concentration of Apramycin can be decreased when it is combined with Hetacillin. |
| Gentamicin C1a | The serum concentration of Gentamicin C1a can be decreased when it is combined with Hetacillin. |
| Neamine | The serum concentration of Neamine can be decreased when it is combined with Hetacillin. |
| Arbekacin | The serum concentration of Arbekacin can be decreased when it is combined with Hetacillin. |
| Puromycin | The serum concentration of Puromycin can be decreased when it is combined with Hetacillin. |
| Dihydrostreptomycin | The serum concentration of Dihydrostreptomycin can be decreased when it is combined with Hetacillin. |
| Hygromycin B | The serum concentration of Hygromycin B can be decreased when it is combined with Hetacillin. |
| Sisomicin | The serum concentration of Sisomicin can be decreased when it is combined with Hetacillin. |
| Plazomicin | The serum concentration of Plazomicin can be decreased when it is combined with Hetacillin. |
| Isepamicin | The serum concentration of Isepamicin can be decreased when it is combined with Hetacillin. |
| Colistin | The serum concentration of Colistin can be decreased when it is combined with Hetacillin. |
| BCG vaccine | The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Hetacillin. |
| Typhoid vaccine | The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Hetacillin. |
| Acemetacin | Acemetacin may decrease the excretion rate of Hetacillin which could result in a higher serum level. |
| Dicoumarol | Hetacillin may increase the anticoagulant activities of Dicoumarol. |
| Phenindione | Hetacillin may increase the anticoagulant activities of Phenindione. |
| Warfarin | Hetacillin may increase the anticoagulant activities of Warfarin. |
| Phenprocoumon | Hetacillin may increase the anticoagulant activities of Phenprocoumon. |
| Acenocoumarol | Hetacillin may increase the anticoagulant activities of Acenocoumarol. |
| 4-hydroxycoumarin | Hetacillin may increase the anticoagulant activities of 4-hydroxycoumarin. |
| Coumarin | Hetacillin may increase the anticoagulant activities of Coumarin. |
| (R)-warfarin | Hetacillin may increase the anticoagulant activities of (R)-warfarin. |
| Ethyl biscoumacetate | Hetacillin may increase the anticoagulant activities of Ethyl biscoumacetate. |
| Fluindione | Hetacillin may increase the anticoagulant activities of Fluindione. |
| Clorindione | Hetacillin may increase the anticoagulant activities of Clorindione. |
| Diphenadione | Hetacillin may increase the anticoagulant activities of Diphenadione. |