Peringatan Keamanan

Excessive doses can be expected to produce enhanced pharmacological effects. Overdosage may increase the risk of histamine release and cardiovascular effects, especially hypotension.

Atracurium besylate

DB00732

small molecule approved

Deskripsi

A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.

Struktur Molekul 2D

Berat 1243.49
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) The elimination half-life is approximately 20 minutes.
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1113 Data
Buprenorphine Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Atracurium besylate.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Atracurium besylate.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Atracurium besylate.
Hydrocodone Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Atracurium besylate.
Magnesium sulfate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Atracurium besylate may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Atracurium besylate.
Mirtazapine Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Atracurium besylate.
Orphenadrine Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Atracurium besylate.
Pramipexole Atracurium besylate may increase the sedative activities of Pramipexole.
Ropinirole Atracurium besylate may increase the sedative activities of Ropinirole.
Rotigotine Atracurium besylate may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Atracurium besylate.
Sodium oxybate Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Atracurium besylate.
Thalidomide Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Capreomycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Capreomycin.
Cyclosporine The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Cyclosporine.
Doxycycline The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Doxycycline.
Lymecycline The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Lymecycline.
Framycetin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Framycetin.
Clomocycline The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Clomocycline.
Quinine The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Quinine.
Vancomycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Vancomycin.
Tigecycline The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Tigecycline.
Oxytetracycline The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Oxytetracycline.
Chloroquine The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Chloroquine.
Demeclocycline The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Demeclocycline.
Mecamylamine The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Mecamylamine.
Tobramycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Tobramycin.
Tetracycline The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Tetracycline.
Gentamicin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Gentamicin.
Etacrynic acid The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Etacrynic acid.
Quinidine The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Quinidine.
Metacycline The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Metacycline.
Netilmicin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Netilmicin.
Neomycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Neomycin.
Streptomycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Streptomycin.
Colistimethate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Colistimethate.
Kanamycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Kanamycin.
Rolitetracycline The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Rolitetracycline.
Magnesium oxide The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium oxide.
Magnesium cation The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium cation.
Paromomycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Paromomycin.
Lincomycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Lincomycin.
Ribostamycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Ribostamycin.
Geneticin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Geneticin.
Apramycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Apramycin.
Gentamicin C1a The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Gentamicin C1a.
Neamine The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Neamine.
Arbekacin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Arbekacin.
Viomycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Viomycin.
Puromycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Puromycin.
Magnesium hydroxide The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium hydroxide.
Magnesium trisilicate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium trisilicate.
Magnesium chloride The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium chloride.
Magnesium acetate tetrahydrate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium acetate tetrahydrate.
Magnesium carbonate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium carbonate.
Magnesium citrate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium citrate.
Magnesium glycinate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium glycinate.
Magnesium Aluminum Silicate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium Aluminum Silicate.
Dihydrostreptomycin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Dihydrostreptomycin.
Hygromycin B The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Hygromycin B.
Sisomicin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Sisomicin.
Plazomicin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Plazomicin.
Magnesium silicate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium silicate.
Penimepicycline The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Penimepicycline.
Magnesium aspartate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium aspartate.
Isepamicin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Isepamicin.
Magnesium gluconate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium gluconate.
Magnesium orotate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium orotate.
Magnesium phosphate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium phosphate.
Magnesium acetate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium acetate.
Procainamide The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Procainamide.
Dantrolene The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Dantrolene.
Piperacillin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Piperacillin.
Magnesium stearate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Magnesium stearate.
Colistin The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Colistin.
Secretin porcine The therapeutic efficacy of Secretin porcine can be decreased when used in combination with Atracurium besylate.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Atracurium besylate.
Spironolactone Spironolactone may increase the neuromuscular blocking activities of Atracurium besylate.
Botulinum toxin type A The risk or severity of adverse effects can be increased when Atracurium besylate is combined with Botulinum toxin type A.
Botulinum toxin type B The risk or severity of adverse effects can be increased when Atracurium besylate is combined with Botulinum toxin type B.
Ethanol Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Atracurium besylate may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Atracurium besylate.
Fluvoxamine The risk or severity of adverse effects can be increased when Atracurium besylate is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Atracurium besylate is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Atracurium besylate is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Atracurium besylate is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Atracurium besylate is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Atracurium besylate is combined with Sertraline.

Target Protein

Neuronal acetylcholine receptor subunit alpha-2 CHRNA2

Referensi & Sumber

Synthesis reference: Steven A. Chamberlin, Ashok V. Bhatia, Deborah A. Davis, Keith A. Drengler, "Process for the preparation and isolation of atracurium besylate." U.S. Patent US5684154, issued September, 1995.

Contoh Produk & Brand

Produk: 26 • International brands: 0
Produk
  • Atracurium - (for Multiple Dose Vial - With Preservative)
    Solution • 10 mg / mL • Intravenous • Canada • Approved
  • Atracurium - (for Single Dose )
    Solution • 10 mg / mL • Intravenous • Canada • Approved
  • Atracurium Besylate
    Injection, solution • 50 mg/5mL • Intravenous • US • Generic • Approved
  • Atracurium Besylate
    Injection, solution • 100 mg/10mL • Intravenous • US • Generic • Approved
  • Atracurium Besylate
    Injection • 10 mg/1mL • Intravenous • US • Generic • Approved
  • Atracurium Besylate
    Injection • 10 mg/1mL • Intravenous • US • Generic • Approved
  • Atracurium Besylate
    Injection • 10 mg/1mL • Intravenous • US • Generic • Approved
  • Atracurium Besylate
    Injection • 10 mg/1mL • Intravenous • US • Generic • Approved
Menampilkan 8 dari 26 produk.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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