Overdosage may be associated with transient disturbances of vision and psychic alterations. The oral LD 50 is 3.6 g/kg, 3.1 g/kg and 3.8 g/kg in the mouse, rat, and rabbit respectively.
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Deferasirox | The serum concentration of Thiabendazole can be increased when it is combined with Deferasirox. |
| Peginterferon alfa-2b | The serum concentration of Thiabendazole can be increased when it is combined with Peginterferon alfa-2b. |
| Leflunomide | The serum concentration of Thiabendazole can be decreased when it is combined with Leflunomide. |
| Teriflunomide | The serum concentration of Thiabendazole can be decreased when it is combined with Teriflunomide. |
| Caffeine | The metabolism of Caffeine can be decreased when combined with Thiabendazole. |
| Theophylline | The metabolism of Theophylline can be decreased when combined with Thiabendazole. |
| Dyphylline | The metabolism of Dyphylline can be decreased when combined with Thiabendazole. |
| Pentoxifylline | The metabolism of Pentoxifylline can be decreased when combined with Thiabendazole. |
| Mercaptopurine | The metabolism of Mercaptopurine can be decreased when combined with Thiabendazole. |
| Aminophylline | The metabolism of Aminophylline can be decreased when combined with Thiabendazole. |
| Oxtriphylline | The metabolism of Oxtriphylline can be decreased when combined with Thiabendazole. |
| Theobromine | The metabolism of Theobromine can be decreased when combined with Thiabendazole. |
| Fenethylline | The metabolism of Fenethylline can be decreased when combined with Thiabendazole. |
| 8-azaguanine | The metabolism of 8-azaguanine can be decreased when combined with Thiabendazole. |
| 7,9-Dimethylguanine | The metabolism of 7,9-Dimethylguanine can be decreased when combined with Thiabendazole. |
| Xanthine | The metabolism of Xanthine can be decreased when combined with Thiabendazole. |
| 7-Deazaguanine | The metabolism of 7-Deazaguanine can be decreased when combined with Thiabendazole. |
| Guanine | The metabolism of Guanine can be decreased when combined with Thiabendazole. |
| 9-Methylguanine | The metabolism of 9-Methylguanine can be decreased when combined with Thiabendazole. |
| Peldesine | The metabolism of Peldesine can be decreased when combined with Thiabendazole. |
| Hypoxanthine | The metabolism of Hypoxanthine can be decreased when combined with Thiabendazole. |
| 9-Deazaguanine | The metabolism of 9-Deazaguanine can be decreased when combined with Thiabendazole. |
| Propentofylline | The metabolism of Propentofylline can be decreased when combined with Thiabendazole. |
| Valomaciclovir | The metabolism of Valomaciclovir can be decreased when combined with Thiabendazole. |
| 3-isobutyl-1-methyl-7H-xanthine | The metabolism of 3-isobutyl-1-methyl-7H-xanthine can be decreased when combined with Thiabendazole. |
| Uric acid | The metabolism of Uric acid can be decreased when combined with Thiabendazole. |
| Doxofylline | The metabolism of Doxofylline can be decreased when combined with Thiabendazole. |
| 6-O-benzylguanine | The metabolism of 6-O-benzylguanine can be decreased when combined with Thiabendazole. |
| Lisofylline | The metabolism of Lisofylline can be decreased when combined with Thiabendazole. |
| Lobucavir | The metabolism of Lobucavir can be decreased when combined with Thiabendazole. |
| Cafedrine | The metabolism of Cafedrine can be decreased when combined with Thiabendazole. |
| Theodrenaline | The metabolism of Theodrenaline can be decreased when combined with Thiabendazole. |
| Bamifylline | The metabolism of Bamifylline can be decreased when combined with Thiabendazole. |
| Proxyphylline | The metabolism of Proxyphylline can be decreased when combined with Thiabendazole. |
| Acefylline | The metabolism of Acefylline can be decreased when combined with Thiabendazole. |
| Etamiphylline | The metabolism of Etamiphylline can be decreased when combined with Thiabendazole. |
| Pentifylline | The metabolism of Pentifylline can be decreased when combined with Thiabendazole. |
| Bufylline | The metabolism of Bufylline can be decreased when combined with Thiabendazole. |
| Bromotheophylline | The metabolism of Bromotheophylline can be decreased when combined with Thiabendazole. |
| Furafylline | The metabolism of Furafylline can be decreased when combined with Thiabendazole. |
| 8-chlorotheophylline | The metabolism of 8-chlorotheophylline can be decreased when combined with Thiabendazole. |
| PCS-499 | The metabolism of PCS-499 can be decreased when combined with Thiabendazole. |
| Zolmitriptan | The metabolism of Zolmitriptan can be decreased when combined with Thiabendazole. |
| Abiraterone | The serum concentration of Thiabendazole can be increased when it is combined with Abiraterone. |
| Cyproterone acetate | The metabolism of Thiabendazole can be increased when combined with Cyproterone acetate. |
| Primidone | The metabolism of Thiabendazole can be increased when combined with Primidone. |
| Rifampin | The metabolism of Thiabendazole can be increased when combined with Rifampicin. |
| Albendazole | The metabolism of Thiabendazole can be increased when combined with Albendazole. |
| Carbamazepine | The metabolism of Thiabendazole can be increased when combined with Carbamazepine. |
| Moxifloxacin | The metabolism of Thiabendazole can be decreased when combined with Moxifloxacin. |
| Lidocaine | The metabolism of Thiabendazole can be decreased when combined with Lidocaine. |
| Mexiletine | The metabolism of Thiabendazole can be decreased when combined with Mexiletine. |
| Alosetron | The metabolism of Thiabendazole can be decreased when combined with Alosetron. |
| Ketoconazole | The metabolism of Thiabendazole can be decreased when combined with Ketoconazole. |
| Gatifloxacin | The metabolism of Thiabendazole can be decreased when combined with Gatifloxacin. |
| Simeprevir | The metabolism of Thiabendazole can be decreased when combined with Simeprevir. |
| Lobeglitazone | The metabolism of Thiabendazole can be decreased when combined with Lobeglitazone. |
| Pazufloxacin | The metabolism of Thiabendazole can be decreased when combined with Pazufloxacin. |
| Osilodrostat | The metabolism of Thiabendazole can be decreased when combined with Osilodrostat. |
| Osimertinib | The serum concentration of Thiabendazole can be decreased when it is combined with Osimertinib. |
| Vemurafenib | The serum concentration of Thiabendazole can be increased when it is combined with Vemurafenib. |
| Cyclosporine | Cyclosporine may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Icosapent | Icosapent may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Cefotiam | Cefotiam may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Mesalazine | Mesalazine may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Cefmenoxime | Cefmenoxime may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Cefmetazole | Cefmetazole may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Pamidronic acid | Pamidronic acid may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Tenofovir disoproxil | Tenofovir disoproxil may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Indomethacin | Indomethacin may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Cidofovir | Cidofovir may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Cefpiramide | Cefpiramide may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Ceftazidime | Ceftazidime may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Loracarbef | Loracarbef may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Cefalotin | Cefalotin may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Ketorolac | Ketorolac may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Tenoxicam | Tenoxicam may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Celecoxib | Celecoxib may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Cefotaxime | Cefotaxime may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Tolmetin | Tolmetin may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Foscarnet | Foscarnet may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Piroxicam | Piroxicam may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Cephalexin | Cephalexin may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Fenoprofen | Fenoprofen may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Valaciclovir | Valaciclovir may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Valdecoxib | Valdecoxib may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Sulindac | Sulindac may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Bacitracin | Bacitracin may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Amphotericin B | Amphotericin B may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Cephaloglycin | Cephaloglycin may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Flurbiprofen | Flurbiprofen may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Adefovir dipivoxil | Adefovir dipivoxil may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Pentamidine | Pentamidine may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Etodolac | Etodolac may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Sulfasalazine | Sulfasalazine may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Phenylbutazone | Phenylbutazone may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Meloxicam | Meloxicam may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Carprofen | Carprofen may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Cefaclor | Cefaclor may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |
| Diflunisal | Diflunisal may decrease the excretion rate of Thiabendazole which could result in a higher serum level. |