Nicergoline

DB00699

small molecule approved investigational

Deskripsi

An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.

Struktur Molekul 2D

Berat 484.386
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

912 Data
Valsartan Nicergoline may decrease the antihypertensive activities of Valsartan.
Ramipril Nicergoline may decrease the antihypertensive activities of Ramipril.
Reserpine Nicergoline may decrease the antihypertensive activities of Reserpine.
Remikiren Nicergoline may decrease the antihypertensive activities of Remikiren.
Torasemide Nicergoline may decrease the antihypertensive activities of Torasemide.
Guanadrel Nicergoline may decrease the antihypertensive activities of Guanadrel.
Olmesartan Nicergoline may decrease the antihypertensive activities of Olmesartan.
Chlorthalidone Nicergoline may decrease the antihypertensive activities of Chlorthalidone.
Nitroprusside Nicergoline may decrease the antihypertensive activities of Nitroprusside.
Minoxidil Nicergoline may decrease the antihypertensive activities of Minoxidil.
Treprostinil Nicergoline may decrease the antihypertensive activities of Treprostinil.
Bendroflumethiazide Nicergoline may decrease the antihypertensive activities of Bendroflumethiazide.
Fosinopril Nicergoline may decrease the antihypertensive activities of Fosinopril.
Trandolapril Nicergoline may decrease the antihypertensive activities of Trandolapril.
Metolazone Nicergoline may decrease the antihypertensive activities of Metolazone.
Benazepril Nicergoline may decrease the antihypertensive activities of Benazepril.
Bosentan Nicergoline may decrease the antihypertensive activities of Bosentan.
Enalapril Nicergoline may decrease the antihypertensive activities of Enalapril.
Cyclothiazide Nicergoline may decrease the antihypertensive activities of Cyclothiazide.
Candoxatril Nicergoline may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Nicergoline may decrease the antihypertensive activities of Mecamylamine.
Losartan Nicergoline may decrease the antihypertensive activities of Losartan.
Moexipril Nicergoline may decrease the antihypertensive activities of Moexipril.
Eplerenone Nicergoline may decrease the antihypertensive activities of Eplerenone.
Lisinopril Nicergoline may decrease the antihypertensive activities of Lisinopril.
Metyrosine Nicergoline may decrease the antihypertensive activities of Metyrosine.
Hydroflumethiazide Nicergoline may decrease the antihypertensive activities of Hydroflumethiazide.
Cryptenamine Nicergoline may decrease the antihypertensive activities of Cryptenamine.
Perindopril Nicergoline may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Nicergoline may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Nicergoline may decrease the antihypertensive activities of Fenoldopam.
Indapamide Nicergoline may decrease the antihypertensive activities of Indapamide.
Eprosartan Nicergoline may decrease the antihypertensive activities of Eprosartan.
Chlorothiazide Nicergoline may decrease the antihypertensive activities of Chlorothiazide.
Quinapril Nicergoline may decrease the antihypertensive activities of Quinapril.
Telmisartan Nicergoline may decrease the antihypertensive activities of Telmisartan.
Hydrochlorothiazide Nicergoline may decrease the antihypertensive activities of Hydrochlorothiazide.
Trichlormethiazide Nicergoline may decrease the antihypertensive activities of Trichlormethiazide.
Irbesartan Nicergoline may decrease the antihypertensive activities of Irbesartan.
Deserpidine Nicergoline may decrease the antihypertensive activities of Deserpidine.
Pentolinium Nicergoline may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Nicergoline may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Nicergoline may decrease the antihypertensive activities of Diazoxide.
Bretylium Nicergoline may decrease the antihypertensive activities of Bretylium.
Guanethidine Nicergoline may decrease the antihypertensive activities of Guanethidine.
Epoprostenol Nicergoline may decrease the antihypertensive activities of Epoprostenol.
Hydralazine Nicergoline may decrease the antihypertensive activities of Hydralazine.
Polythiazide Nicergoline may decrease the antihypertensive activities of Polythiazide.
Cilazapril Nicergoline may decrease the antihypertensive activities of Cilazapril.
Saprisartan Nicergoline may decrease the antihypertensive activities of Saprisartan.
Spirapril Nicergoline may decrease the antihypertensive activities of Spirapril.
Tienilic acid Nicergoline may decrease the antihypertensive activities of Tienilic acid.
Sitaxentan Nicergoline may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Nicergoline may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Nicergoline may decrease the antihypertensive activities of Diethylnorspermine.
Pinacidil Nicergoline may decrease the antihypertensive activities of Pinacidil.
Temocapril Nicergoline may decrease the antihypertensive activities of Temocapril.
Riociguat Nicergoline may decrease the antihypertensive activities of Riociguat.
Macitentan Nicergoline may decrease the antihypertensive activities of Macitentan.
Hexamethonium Nicergoline may decrease the antihypertensive activities of Hexamethonium.
Aliskiren Nicergoline may decrease the antihypertensive activities of Aliskiren.
Nicorandil Nicergoline may decrease the antihypertensive activities of Nicorandil.
Rauwolfia serpentina root Nicergoline may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Nicergoline may decrease the antihypertensive activities of Enalaprilat.
Selexipag Nicergoline may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Nicergoline may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Nicergoline may decrease the antihypertensive activities of Imidapril.
BQ-123 Nicergoline may decrease the antihypertensive activities of BQ-123.
Cicletanine Nicergoline may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Nicergoline may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Nicergoline may decrease the antihypertensive activities of Zofenopril.
Guanoxan Nicergoline may decrease the antihypertensive activities of Guanoxan.
Delapril Nicergoline may decrease the antihypertensive activities of Delapril.
Vincamine Nicergoline may decrease the antihypertensive activities of Vincamine.
Linsidomine Nicergoline may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Nicergoline may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Nicergoline may decrease the antihypertensive activities of Tolonidine.
Endralazine Nicergoline may decrease the antihypertensive activities of Endralazine.
Cadralazine Nicergoline may decrease the antihypertensive activities of Cadralazine.
Cyclopenthiazide Nicergoline may decrease the antihypertensive activities of Cyclopenthiazide.
Bietaserpine Nicergoline may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Nicergoline may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Nicergoline may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Nicergoline may decrease the antihypertensive activities of Guanoclor.
Muzolimine Nicergoline may decrease the antihypertensive activities of Muzolimine.
Xipamide Nicergoline may decrease the antihypertensive activities of Xipamide.
Candesartan Nicergoline may decrease the antihypertensive activities of Candesartan.
Tocopherylquinone Nicergoline may decrease the antihypertensive activities of Tocopherylquinone.
Benazeprilat Nicergoline may decrease the antihypertensive activities of Benazeprilat.
Fosinoprilat Nicergoline may decrease the antihypertensive activities of Fosinoprilat.
Ramiprilat Nicergoline may decrease the antihypertensive activities of Ramiprilat.
Perindoprilat Nicergoline may decrease the antihypertensive activities of Perindoprilat.
Quinaprilat Nicergoline may decrease the antihypertensive activities of Quinaprilat.
Furosemide Nicergoline may decrease the antihypertensive activities of Furosemide.
Captopril Nicergoline may decrease the antihypertensive activities of Captopril.
Levamlodipine Nicergoline may decrease the antihypertensive activities of Levamlodipine.
Buthiazide Nicergoline may decrease the antihypertensive activities of Buthiazide.
Azilsartan medoxomil Nicergoline may decrease the antihypertensive activities of Azilsartan medoxomil.
Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Nicergoline.
Icosapent The risk or severity of hypertension can be increased when Icosapent is combined with Nicergoline.

Target Protein

Alpha-1A adrenergic receptor ADRA1A

Referensi & Sumber

Artikel (PubMed)
  • PMID: 18666801
    Winblad B, Fioravanti M, Dolezal T, Logina I, Milanov IG, Popescu DC, Solomon A: Therapeutic use of nicergoline. Clin Drug Investig. 2008;28(9):533-52.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
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Sekuens Gen/Protein (FASTA)

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