Peringatan Keamanan

Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.

Cephaloglycin

DB00689

small molecule approved

Deskripsi

A cephalorsporin antibiotic that is no longer commonly used.

Struktur Molekul 2D

Berat 405.425
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Well absorbed following oral administration.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

796 Data
Probenecid The serum concentration of Cephaloglycin can be increased when it is combined with Probenecid.
Foscarnet The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Foscarnet.
Mannitol The risk or severity of nephrotoxicity can be increased when Mannitol is combined with Cephaloglycin.
Tenofovir disoproxil Cephaloglycin may increase the nephrotoxic activities of Tenofovir disoproxil.
Tenofovir alafenamide Cephaloglycin may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir Cephaloglycin may increase the nephrotoxic activities of Tenofovir.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Cephaloglycin.
Cyclosporine The risk or severity of nephrotoxicity can be increased when Cyclosporine is combined with Cephaloglycin.
Icosapent The risk or severity of nephrotoxicity can be increased when Icosapent is combined with Cephaloglycin.
Cefotiam The risk or severity of nephrotoxicity can be increased when Cefotiam is combined with Cephaloglycin.
Mesalazine The risk or severity of nephrotoxicity can be increased when Mesalazine is combined with Cephaloglycin.
Cefmenoxime The risk or severity of nephrotoxicity can be increased when Cefmenoxime is combined with Cephaloglycin.
Cefmetazole The risk or severity of nephrotoxicity can be increased when Cefmetazole is combined with Cephaloglycin.
Indomethacin The risk or severity of nephrotoxicity can be increased when Indomethacin is combined with Cephaloglycin.
Triamterene The risk or severity of nephrotoxicity can be increased when Triamterene is combined with Cephaloglycin.
Cefpiramide The risk or severity of nephrotoxicity can be increased when Cefpiramide is combined with Cephaloglycin.
Loracarbef The risk or severity of nephrotoxicity can be increased when Loracarbef is combined with Cephaloglycin.
Cefalotin The risk or severity of nephrotoxicity can be increased when Cefalotin is combined with Cephaloglycin.
Nabumetone The risk or severity of nephrotoxicity can be increased when Nabumetone is combined with Cephaloglycin.
Ketorolac The risk or severity of nephrotoxicity can be increased when Ketorolac is combined with Cephaloglycin.
Tenoxicam The risk or severity of nephrotoxicity can be increased when Tenoxicam is combined with Cephaloglycin.
Celecoxib The risk or severity of nephrotoxicity can be increased when Celecoxib is combined with Cephaloglycin.
Cefotaxime The risk or severity of nephrotoxicity can be increased when Cefotaxime is combined with Cephaloglycin.
Tolmetin The risk or severity of nephrotoxicity can be increased when Tolmetin is combined with Cephaloglycin.
Rofecoxib The risk or severity of nephrotoxicity can be increased when Rofecoxib is combined with Cephaloglycin.
Fenoprofen The risk or severity of nephrotoxicity can be increased when Fenoprofen is combined with Cephaloglycin.
Valdecoxib The risk or severity of nephrotoxicity can be increased when Valdecoxib is combined with Cephaloglycin.
Diclofenac The risk or severity of nephrotoxicity can be increased when Diclofenac is combined with Cephaloglycin.
Sulindac The risk or severity of nephrotoxicity can be increased when Sulindac is combined with Cephaloglycin.
Bacitracin The risk or severity of nephrotoxicity can be increased when Bacitracin is combined with Cephaloglycin.
Amphotericin B The risk or severity of nephrotoxicity can be increased when Amphotericin B is combined with Cephaloglycin.
Adefovir dipivoxil The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Adefovir dipivoxil.
Pentamidine The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Pentamidine.
Mefenamic acid The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Mefenamic acid.
Naproxen The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Naproxen.
Sulfasalazine The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Sulfasalazine.
Phenylbutazone The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Phenylbutazone.
Meloxicam The risk or severity of methemoglobinemia can be increased when Cephaloglycin is combined with Meloxicam.
Carprofen The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Carprofen.
Tacrolimus The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Tacrolimus.
Etacrynic acid The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Etacrynic acid.
Ceforanide The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Ceforanide.
Salicylic acid The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Salicylic acid.
Acetylsalicylic acid The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Acetylsalicylic acid.
Hydrochlorothiazide The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Hydrochlorothiazide.
Balsalazide The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Balsalazide.
Cefditoren The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefditoren.
Atazanavir The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Atazanavir.
Colistimethate The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Colistimethate.
Cefuroxime The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefuroxime.
Cefapirin The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefapirin.
Cefprozil The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefprozil.
Olsalazine The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Olsalazine.
Lumiracoxib The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Lumiracoxib.
Cefamandole The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefamandole.
Cefazolin The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefazolin.
Cefonicid The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefonicid.
Cefoperazone The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefoperazone.
Cefoxitin The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefoxitin.
Ceftizoxime The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Ceftizoxime.
Magnesium salicylate The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Magnesium salicylate.
Salsalate The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Salsalate.
Choline magnesium trisalicylate The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Choline magnesium trisalicylate.
Cefepime The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefepime.
Cefacetrile The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefacetrile.
Cefpodoxime The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefpodoxime.
Antrafenine The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Antrafenine.
Aminophenazone The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Aminophenazone.
Antipyrine The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Antipyrine.
Tiaprofenic acid The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Tiaprofenic acid.
Lopinavir The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Lopinavir.
Etoricoxib The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Etoricoxib.
Hydrolyzed Cephalothin The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Hydrolyzed Cephalothin.
Cephalothin Group The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cephalothin Group.
Oxyphenbutazone The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Oxyphenbutazone.
Latamoxef The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Latamoxef.
Nimesulide The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Nimesulide.
Benoxaprofen The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Benoxaprofen.
Metamizole The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Metamizole.
Zomepirac The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Zomepirac.
Ceftobiprole The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Ceftobiprole.
Cimicoxib The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cimicoxib.
Ceftaroline fosamil The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Ceftaroline fosamil.
Lornoxicam The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Lornoxicam.
Zaltoprofen The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Zaltoprofen.
Azapropazone The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Azapropazone.
Parecoxib The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Parecoxib.
Salicylamide The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Salicylamide.
Kebuzone The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Kebuzone.
Isoxicam The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Isoxicam.
Indoprofen The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Indoprofen.
Ibuproxam The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Ibuproxam.
Floctafenine The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Floctafenine.
Fenbufen The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Fenbufen.
Etofenamate The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Etofenamate.
Epirizole The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Epirizole.
Cefaloridine The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefaloridine.
Cefminox The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Cefminox.
Dexibuprofen The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Dexibuprofen.
Droxicam The risk or severity of nephrotoxicity can be increased when Cephaloglycin is combined with Droxicam.

Target Protein

Penicillin-binding protein 1B mrcB

Referensi & Sumber

Synthesis reference: Wall, W.F., Fatherey, M. and Boothroyd, 6.; U.S. Patent 3,422,103; January 14,1969; assigned to Glaxo Laboratories, Ltd. Pfeiffer, R.R. and Bottorff, E.M.; US. Patent 3,497,505; February 24,1970; assigned to Eli Lilly & Co. Jackson, B.G.; U.S. Patent 3,671,449; June 20,1972; assigned to Eli Lilly & Co.
Artikel (PubMed)
  • PMID: 2133431
    Tune BM, Hsu CY: The renal mitochondrial toxicity of beta-lactam antibiotics: in vitro effects of cephaloglycin and imipenem. J Am Soc Nephrol. 1990 Nov;1(5):815-21.
  • PMID: 2930580
    Tune BM, Fravert D, Hsu CY: Oxidative and mitochondrial toxic effects of cephalosporin antibiotics in the kidney. A comparative study of cephaloridine and cephaloglycin. Biochem Pharmacol. 1989 Mar 1;38(5):795-802.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Kafocin — Lilly

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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