Peringatan Keamanan

Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.

Isoflurophate

DB00677

small molecule approved investigational withdrawn

Deskripsi

An irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically. (From Martindale, The Extra Pharmacopoeia, 29th ed, p1330)

Struktur Molekul 2D

Berat 184.1457
Wujud liquid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

292 Data
Dipyridamole The therapeutic efficacy of Isoflurophate can be decreased when used in combination with Dipyridamole.
Ephedrine Isoflurophate may increase the neuromuscular blocking activities of Ephedrine.
Bambuterol Isoflurophate may increase the neuromuscular blocking activities of Bambuterol.
Clevidipine Isoflurophate may increase the neuromuscular blocking activities of Clevidipine.
Sar9, Met (O2)11-Substance P Isoflurophate may increase the neuromuscular blocking activities of Sar9, Met (O2)11-Substance P.
Mirabegron Isoflurophate may increase the neuromuscular blocking activities of Mirabegron.
Moxisylyte Isoflurophate may increase the neuromuscular blocking activities of Moxisylyte.
Propacetamol Isoflurophate may increase the neuromuscular blocking activities of Propacetamol.
Procaine Isoflurophate may increase the neuromuscular blocking activities of Procaine.
Cocaine Isoflurophate may increase the neuromuscular blocking activities of Cocaine.
Trimethaphan Isoflurophate may increase the neuromuscular blocking activities of Trimethaphan.
Doxacurium Isoflurophate may increase the neuromuscular blocking activities of Doxacurium.
Chloroprocaine Isoflurophate may increase the neuromuscular blocking activities of Chloroprocaine.
Tubocurarine Isoflurophate may increase the neuromuscular blocking activities of Tubocurarine.
Aclidinium Isoflurophate may increase the neuromuscular blocking activities of Aclidinium.
Butyrylthiocholine Isoflurophate may increase the neuromuscular blocking activities of Butyrylthiocholine.
Oxybuprocaine Isoflurophate may increase the neuromuscular blocking activities of Oxybuprocaine.
Benzonatate Isoflurophate may increase the neuromuscular blocking activities of Benzonatate.
Succinylcholine The metabolism of Succinylcholine can be decreased when combined with Isoflurophate.
Tramadol The therapeutic efficacy of Tramadol can be decreased when used in combination with Isoflurophate.
Trospium The therapeutic efficacy of Trospium can be decreased when used in combination with Isoflurophate.
Oxyphenonium The therapeutic efficacy of Oxyphenonium can be decreased when used in combination with Isoflurophate.
Butabarbital The therapeutic efficacy of Butabarbital can be decreased when used in combination with Isoflurophate.
Butalbital The therapeutic efficacy of Butalbital can be decreased when used in combination with Isoflurophate.
Benzatropine The therapeutic efficacy of Benzatropine can be decreased when used in combination with Isoflurophate.
Ziprasidone The therapeutic efficacy of Ziprasidone can be decreased when used in combination with Isoflurophate.
Disopyramide The therapeutic efficacy of Disopyramide can be decreased when used in combination with Isoflurophate.
Talbutal The therapeutic efficacy of Talbutal can be decreased when used in combination with Isoflurophate.
Pentobarbital The therapeutic efficacy of Pentobarbital can be decreased when used in combination with Isoflurophate.
Amitriptyline The therapeutic efficacy of Amitriptyline can be decreased when used in combination with Isoflurophate.
Ipratropium The therapeutic efficacy of Ipratropium can be decreased when used in combination with Isoflurophate.
Methadone The therapeutic efficacy of Methadone can be decreased when used in combination with Isoflurophate.
Olanzapine The therapeutic efficacy of Olanzapine can be decreased when used in combination with Isoflurophate.
Metixene The therapeutic efficacy of Metixene can be decreased when used in combination with Isoflurophate.
Terfenadine The therapeutic efficacy of Terfenadine can be decreased when used in combination with Isoflurophate.
Buclizine The therapeutic efficacy of Buclizine can be decreased when used in combination with Isoflurophate.
Clozapine The therapeutic efficacy of Clozapine can be decreased when used in combination with Isoflurophate.
Doxylamine The therapeutic efficacy of Doxylamine can be decreased when used in combination with Isoflurophate.
Trihexyphenidyl The therapeutic efficacy of Trihexyphenidyl can be decreased when used in combination with Isoflurophate.
Oxyphencyclimine The therapeutic efficacy of Oxyphencyclimine can be decreased when used in combination with Isoflurophate.
Procyclidine The therapeutic efficacy of Procyclidine can be decreased when used in combination with Isoflurophate.
Profenamine The therapeutic efficacy of Profenamine can be decreased when used in combination with Isoflurophate.
Secobarbital The therapeutic efficacy of Secobarbital can be decreased when used in combination with Isoflurophate.
Promazine The therapeutic efficacy of Promazine can be decreased when used in combination with Isoflurophate.
Hyoscyamine The therapeutic efficacy of Hyoscyamine can be decreased when used in combination with Isoflurophate.
Cyproheptadine The therapeutic efficacy of Cyproheptadine can be decreased when used in combination with Isoflurophate.
Imipramine The therapeutic efficacy of Imipramine can be decreased when used in combination with Isoflurophate.
Methscopolamine bromide The therapeutic efficacy of Methscopolamine bromide can be decreased when used in combination with Isoflurophate.
Metharbital The therapeutic efficacy of Metharbital can be decreased when used in combination with Isoflurophate.
Fluoxetine The therapeutic efficacy of Fluoxetine can be decreased when used in combination with Isoflurophate.
Chlorpromazine The therapeutic efficacy of Chlorpromazine can be decreased when used in combination with Isoflurophate.
Darifenacin The therapeutic efficacy of Darifenacin can be decreased when used in combination with Isoflurophate.
Tridihexethyl The therapeutic efficacy of Tridihexethyl can be decreased when used in combination with Isoflurophate.
Triflupromazine The therapeutic efficacy of Triflupromazine can be decreased when used in combination with Isoflurophate.
Dextromethorphan The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Isoflurophate.
Anisotropine methylbromide The therapeutic efficacy of Anisotropine methylbromide can be decreased when used in combination with Isoflurophate.
Nortriptyline The therapeutic efficacy of Nortriptyline can be decreased when used in combination with Isoflurophate.
Amoxapine The therapeutic efficacy of Amoxapine can be decreased when used in combination with Isoflurophate.
Atropine The therapeutic efficacy of Atropine can be decreased when used in combination with Isoflurophate.
Thiopental The therapeutic efficacy of Thiopental can be decreased when used in combination with Isoflurophate.
Nicardipine The therapeutic efficacy of Nicardipine can be decreased when used in combination with Isoflurophate.
Mecamylamine The therapeutic efficacy of Mecamylamine can be decreased when used in combination with Isoflurophate.
Pirenzepine The therapeutic efficacy of Pirenzepine can be decreased when used in combination with Isoflurophate.
Paroxetine The therapeutic efficacy of Paroxetine can be decreased when used in combination with Isoflurophate.
Homatropine methylbromide The therapeutic efficacy of Homatropine methylbromide can be decreased when used in combination with Isoflurophate.
Scopolamine The therapeutic efficacy of Scopolamine can be decreased when used in combination with Isoflurophate.
Isoflurane The therapeutic efficacy of Isoflurane can be decreased when used in combination with Isoflurophate.
Benzquinamide The therapeutic efficacy of Benzquinamide can be decreased when used in combination with Isoflurophate.
Clidinium The therapeutic efficacy of Clidinium can be decreased when used in combination with Isoflurophate.
Propiomazine The therapeutic efficacy of Propiomazine can be decreased when used in combination with Isoflurophate.
Propantheline The therapeutic efficacy of Propantheline can be decreased when used in combination with Isoflurophate.
Primidone The therapeutic efficacy of Primidone can be decreased when used in combination with Isoflurophate.
Dicyclomine The therapeutic efficacy of Dicyclomine can be decreased when used in combination with Isoflurophate.
Biperiden The therapeutic efficacy of Biperiden can be decreased when used in combination with Isoflurophate.
Brompheniramine The therapeutic efficacy of Brompheniramine can be decreased when used in combination with Isoflurophate.
Methylphenobarbital The therapeutic efficacy of Methylphenobarbital can be decreased when used in combination with Isoflurophate.
Quinidine The therapeutic efficacy of Quinidine can be decreased when used in combination with Isoflurophate.
Amantadine The therapeutic efficacy of Amantadine can be decreased when used in combination with Isoflurophate.
Maprotiline The therapeutic efficacy of Maprotiline can be decreased when used in combination with Isoflurophate.
Methantheline The therapeutic efficacy of Methantheline can be decreased when used in combination with Isoflurophate.
Hexafluronium The therapeutic efficacy of Hexafluronium can be decreased when used in combination with Isoflurophate.
Cycrimine The therapeutic efficacy of Cycrimine can be decreased when used in combination with Isoflurophate.
Desloratadine The therapeutic efficacy of Desloratadine can be decreased when used in combination with Isoflurophate.
Glycopyrronium The therapeutic efficacy of Glycopyrronium can be decreased when used in combination with Isoflurophate.
Tolterodine The therapeutic efficacy of Tolterodine can be decreased when used in combination with Isoflurophate.
Oxybutynin The therapeutic efficacy of Oxybutynin can be decreased when used in combination with Isoflurophate.
Promethazine The therapeutic efficacy of Promethazine can be decreased when used in combination with Isoflurophate.
Diphenhydramine The therapeutic efficacy of Diphenhydramine can be decreased when used in combination with Isoflurophate.
Pentolinium The therapeutic efficacy of Pentolinium can be decreased when used in combination with Isoflurophate.
Doxepin The therapeutic efficacy of Doxepin can be decreased when used in combination with Isoflurophate.
Flavoxate The therapeutic efficacy of Flavoxate can be decreased when used in combination with Isoflurophate.
Desipramine The therapeutic efficacy of Desipramine can be decreased when used in combination with Isoflurophate.
Orphenadrine The therapeutic efficacy of Orphenadrine can be decreased when used in combination with Isoflurophate.
Phenobarbital The therapeutic efficacy of Phenobarbital can be decreased when used in combination with Isoflurophate.
Escitalopram The therapeutic efficacy of Escitalopram can be decreased when used in combination with Isoflurophate.
Quetiapine The therapeutic efficacy of Quetiapine can be decreased when used in combination with Isoflurophate.
Levacetylmethadol The therapeutic efficacy of Levacetylmethadol can be decreased when used in combination with Isoflurophate.
Diphenidol The therapeutic efficacy of Diphenidol can be decreased when used in combination with Isoflurophate.
Aripiprazole The therapeutic efficacy of Aripiprazole can be decreased when used in combination with Isoflurophate.
Chlorprothixene The therapeutic efficacy of Chlorprothixene can be decreased when used in combination with Isoflurophate.

Target Protein

Acetylcholinesterase ACHE
Cholinesterase BCHE
Serotransferrin TF

Referensi & Sumber

Synthesis reference: U.S. Patent 2,409,039.

Contoh Produk & Brand

Produk: 0 • International brands: 4
International Brands
  • Diflupyl
  • Floropryl — Merck
  • Fluopryl — Merck
  • Neoglaucit

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul