An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. It is generally well tolerated by patients.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Aclidinium | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Aclidinium. |
| Mianserin | Mianserin may increase the anticholinergic activities of Pirenzepine. |
| Mirabegron | The risk or severity of urinary retention can be increased when Pirenzepine is combined with Mirabegron. |
| Potassium chloride | The risk or severity of gastrointestinal ulceration can be increased when Pirenzepine is combined with Potassium chloride. |
| Pramlintide | The risk or severity of reduced gastrointestinal motility can be increased when Pramlintide is combined with Pirenzepine. |
| Secretin porcine | The therapeutic efficacy of Secretin porcine can be decreased when used in combination with Pirenzepine. |
| Tiotropium | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Tiotropium. |
| Topiramate | The risk or severity of hyperthermia and oligohydrosis can be increased when Pirenzepine is combined with Topiramate. |
| Umeclidinium | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Umeclidinium. |
| Glycopyrronium | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Glycopyrronium. |
| Botulinum toxin type A | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Botulinum toxin type A. |
| Glucagon | Pirenzepine may increase the gastrointestinal motility reducing activities of Glucagon. |
| Sulpiride | Pirenzepine may increase the anticholinergic activities of Sulpiride. |
| Botulinum toxin type B | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Botulinum toxin type B. |
| Eluxadoline | The risk or severity of constipation can be increased when Pirenzepine is combined with Eluxadoline. |
| Ramosetron | The risk or severity of constipation can be increased when Pirenzepine is combined with Ramosetron. |
| Naltrexone | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Naltrexone. |
| Bezitramide | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Bezitramide. |
| Tramadol | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Tramadol. |
| Morphine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Morphine. |
| Codeine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Codeine. |
| Hydromorphone | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Hydromorphone. |
| Methadone | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Methadone. |
| Meperidine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Meperidine. |
| Oxycodone | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Oxycodone. |
| Butorphanol | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Butorphanol. |
| Dextropropoxyphene | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Dextropropoxyphene. |
| Pentazocine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Pentazocine. |
| Sufentanil | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Sufentanil. |
| Alfentanil | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Alfentanil. |
| Fentanyl | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Fentanyl. |
| Nalbuphine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Nalbuphine. |
| Levorphanol | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Levorphanol. |
| Remifentanil | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Remifentanil. |
| Buprenorphine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Buprenorphine. |
| Hydrocodone | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Hydrocodone. |
| Diphenoxylate | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Diphenoxylate. |
| Oxymorphone | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Oxymorphone. |
| Dezocine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Dezocine. |
| Levacetylmethadol | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Levacetylmethadol. |
| Methadyl acetate | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Methadyl acetate. |
| Dihydroetorphine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Dihydroetorphine. |
| Diamorphine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Diamorphine. |
| Ethylmorphine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Ethylmorphine. |
| Etorphine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Etorphine. |
| Dextromoramide | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Dextromoramide. |
| Desomorphine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Desomorphine. |
| Carfentanil | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Carfentanil. |
| Dihydrocodeine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Dihydrocodeine. |
| Alphacetylmethadol | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Alphacetylmethadol. |
| Dihydromorphine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Dihydromorphine. |
| Tapentadol | The risk or severity of urinary retention and constipation can be increased when Pirenzepine is combined with Tapentadol. |
| Ketobemidone | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Ketobemidone. |
| DPDPE | The risk or severity of adverse effects can be increased when Pirenzepine is combined with DPDPE. |
| Lofentanil | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Lofentanil. |
| Opium | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Opium. |
| Normethadone | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Normethadone. |
| Piritramide | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Piritramide. |
| Alphaprodine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Alphaprodine. |
| Nicomorphine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Nicomorphine. |
| Meptazinol | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Meptazinol. |
| Phenoperidine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Phenoperidine. |
| Phenazocine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Phenazocine. |
| Tilidine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Tilidine. |
| Carfentanil, C-11 | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Carfentanil, C-11. |
| Benzhydrocodone | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Benzhydrocodone. |
| Naloxegol | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Naloxegol. |
| Trospium | The risk or severity of adverse effects can be increased when Trospium is combined with Pirenzepine. |
| Oxyphenonium | The risk or severity of adverse effects can be increased when Oxyphenonium is combined with Pirenzepine. |
| Benzatropine | The risk or severity of adverse effects can be increased when Benzatropine is combined with Pirenzepine. |
| Disopyramide | The risk or severity of adverse effects can be increased when Disopyramide is combined with Pirenzepine. |
| Metixene | The risk or severity of adverse effects can be increased when Metixene is combined with Pirenzepine. |
| Terfenadine | The risk or severity of adverse effects can be increased when Terfenadine is combined with Pirenzepine. |
| Buclizine | The risk or severity of adverse effects can be increased when Buclizine is combined with Pirenzepine. |
| Trihexyphenidyl | The risk or severity of adverse effects can be increased when Trihexyphenidyl is combined with Pirenzepine. |
| Oxyphencyclimine | The risk or severity of adverse effects can be increased when Oxyphencyclimine is combined with Pirenzepine. |
| Procyclidine | The risk or severity of adverse effects can be increased when Procyclidine is combined with Pirenzepine. |
| Hyoscyamine | The risk or severity of adverse effects can be increased when Hyoscyamine is combined with Pirenzepine. |
| Methscopolamine bromide | The risk or severity of adverse effects can be increased when Methscopolamine bromide is combined with Pirenzepine. |
| Darifenacin | The risk or severity of adverse effects can be increased when Darifenacin is combined with Pirenzepine. |
| Tridihexethyl | The risk or severity of adverse effects can be increased when Tridihexethyl is combined with Pirenzepine. |
| Anisotropine methylbromide | The risk or severity of adverse effects can be increased when Anisotropine methylbromide is combined with Pirenzepine. |
| Atropine | The risk or severity of adverse effects can be increased when Atropine is combined with Pirenzepine. |
| Nicardipine | The risk or severity of adverse effects can be increased when Nicardipine is combined with Pirenzepine. |
| Mecamylamine | The risk or severity of adverse effects can be increased when Mecamylamine is combined with Pirenzepine. |
| Homatropine methylbromide | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Homatropine methylbromide. |
| Benzquinamide | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Benzquinamide. |
| Propantheline | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Propantheline. |
| Dicyclomine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Dicyclomine. |
| Tropicamide | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Tropicamide. |
| Cocaine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Cocaine. |
| Quinidine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Quinidine. |
| Amantadine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Amantadine. |
| Methantheline | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Methantheline. |
| Cycrimine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Cycrimine. |
| Cyclopentolate | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Cyclopentolate. |
| Tolterodine | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Tolterodine. |
| Oxybutynin | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Oxybutynin. |
| Pentolinium | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Pentolinium. |
| Trimethaphan | The risk or severity of adverse effects can be increased when Pirenzepine is combined with Trimethaphan. |